Clinical trials: Pain, completed
Nociceptive Pain, Surgical Procedure, Unspecified
Automatic Remifentanil Administration Guided by ANI During Propofol Anesthesia
Prospective Randomized Monocentric Clinical Trial during propofol anesthesia. The aim of the study is to test whether the use of a medical device designed to automatically administer remifentanil during surgery based on expert…
- Trial name
- ANI-LOOP (NCT03556696)
- Testing
- ANI-REMI-loop, remifentanil pK/pD target administration device, Remifentanil
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Lille
Shoulder Impingement Syndrome
Short-term Effects of Thoracic Manipulation in Shoulder Impingement
The hypothesis of this study is that thoracic spine manipulation would reduce pain in subjects with SIS and cause changes in scapular kinematics and muscle activity in subjects with impingement symptoms and in asymptomatic…
- Trial name
- NCT02083796
- Testing
- Shoulder impingement_TSM, Asymptomatic_TSM
- Where
- Brazil
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Painful Diabetic Neuropathy
An Open-label follow-on Trial to Assess the Long-term Safety and Efficacy of Oral SPM 927 in Subjects With Diabetic Neuropathy
The primary objective of the trial is to assess the tolerability and safety of long-term SPM 927 administration in subjects with diabetic neuropathy.
- Trial name
- NCT00861042
- Testing
- SPM927/Lacosamide
- Volunteers
- 69 people
- Sponsor
- UCB Pharma
Dental Pain, Dental Anxiety and Child Behavior Are Assess in Response to Dental Injection
Effect of Computer-controlled vs. Conventional Injection on Pain and Anxiety in Children
This randomized controlled trial aims to compare the effectiveness of Computer-Controlled automatic injection device versus conventional injection techniques in pediatric dental patients.
- Trial name
- NCT07193342
- Testing
- computer controlled automatic injection (Star pen® system), conventional anesthetic syringe
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Future University in Egypt
Neck Pain
The Effects of Spinal Mobilizations on Neck Pain and Sympathetic Nervous System Activity in People With Neck Pain
This study investigates the effects of spinal mobilizations on neck symptoms and sympathetic nervous system activity in people with neck pain.
- Trial name
- NCT03507920
- Testing
- Neck passive mobilizations, Manual contact
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- King's College London
Irritable Bowel Syndrome
Administration of a Molecular Complex of Resins, Polysaccharides and Polyphenols in Irritable Bowel Syndrome.
This study is aimed to investigate the efficacy and safety of Colilen IBS, a Medical Device made of natural substances, even when taken in addition to other therapies, for the treatment of Irritable Bowel Syndrome.
- Trial name
- NCT05016024
- Testing
- Colilen IBS
- Where
- 7 sites in Germany, Italy
- Volunteers
- 71 people
- Sponsor
- Aboca Spa Societa' Agricola
Pain, Postoperative, Mammaplasty
Efficacy of Liposomal Bupivacaine for Prolonged Postoperative Analgesia in Patient Undergoing Breast Reconstruction With Tissue Expander
Patients undergoing breast reconstruction with tissue expanders will be treated with a local anesthetic during their procedure and monitor their post-operative pain level and amount of oral pain medication taken.
- Trial name
- NCT04278846
- Testing
- Depofoam bupivacaine, Bupivacaine hydrochloride (HCl)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Cleveland Clinic
Pain, Postoperative, Surgery
Effect of Music on Pain and Comfort Levels After Laparoscopic Abdominal Surgery
It is planned to examine the effects of local music on pain and comfort levels in patients undergoing laparoscopic abdominal surgery and to make a comparison between Turkey and Iran with the results obtained.
- Trial name
- NCT06820788
- Testing
- music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bitlis Eren University
Pain
Combined Medication for Improved Analgesia in Superficial Pain
This research study is being done to assess if a combination of medications can enhance the relief of superficial pain (pain at the surface of the skin, such as sunburn pain).
- Trial name
- NCT02194088
- Testing
- Diclofenac and Atropine combination drug
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Cervicogenic Headache
Prevalence of Cervicogenic Headache in Lab Technicians
The purpose of the study is to determine the prevalence of cervicogenic headache among lab technicians
- Trial name
- NCT07067242
- Where
- Pakistan
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Elite College of Management Sciences, Gujranwala, Pakistan
Post Operative Pain
Pain Reduction Using Two Cold Irrigating Protocols in Teeth With Vital Pulps.
The goal of this clinical research was to relate the incidence of post-endodontic pain after one-visit root canal treatment using two cold protocols of irrigation.
- Trial name
- EP18 (NCT03559127)
- Testing
- For the Group A. Applied Cryotherapy at 6 oC, For the Group B. Applied Cryotherapy at 2.5 oC, Control Group (CG). Applied irrigant at room temperature
- Where
- 3 sites in Mexico
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Placebo Effect, Pain Intensity
The Influence of Expectations on Post-needling Soreness and Pain Processing After Dry Needling Treatment
The general objective of the study is to determine the effectiveness on local mechanical hypoalgesia, pain intensity, disability and psychological variables of the deep dry needling technique on a latent trigger point of the…
- Conditions
- Placebo Effect, Pain Intensity, Disability, Dry Needling
- Trial name
- NCT04571827
- Testing
- Dry Needling
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Intrapartum - Moderate and Severe Anaemia
World Maternal Antifibrinolytic Trial_2
Postpartum haemorrhage (PPH) is responsible for about 100,000 maternal deaths every year, almost all of which occur in low and middle income countries.
- Trial name
- WOMAN-2 (NCT03475342)
- Testing
- Tranexamic Acid
- Where
- 41 sites in Nigeria, Pakistan and 2 more
- Volunteers
- 15,068 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Chronic Migraine
Use of the Tx360 Nasal Applicator in the Treatment of Chronic Migraine
Migraine imposes a substantial burden on patients in terms of diminished daily functioning, quality of life, and financial loss.
- Trial name
- Tx360 (NCT01709708)
- Testing
- Marcaine, Saline
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Tian Medical Inc.
Pain, Anxiety
The Effect of Virtual Reality and Music Therapy on Physiological Parameters and Anxiety
Background and Aim: Invasive procedures such as intravenous , intramuscular and subcutaneous Injection practices are among the most frequently performed nursing interventions in ıntensive care units.
- Conditions
- Pain, Anxiety, Physiological Parameter
- Trial name
- NCT06649617
- Testing
- Control Group (Standard Procedure), Music Therapy Group, Virtual Reality Group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Acute Pain
ANI Versus Standard Care in Surgical Patients Receiving Balanced Sevoflurane-Fentanyl Anesthesia
This study aims to be a randomized, controlled study of ANI-guided opioid administration versus standard clinical practice in surgical patients undergoing general anesthesia with balanced sevoflurane-fentanyl.
- Trial name
- NCT03684590
- Testing
- ANI-guided opioid administration, Standard opioid administration
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Low Back Pain
PNF vs Pilates Exercises in Patients With CLBP
Low back pain (LBP) is a common health problem that affects people all over the world and is a leading cause of disability, affecting work performance and overall health.
- Trial name
- NCT05148013
- Testing
- Pilates exercise, PNF exercise
- Where
- Cyprus
- Volunteers
- 60 people
- Sponsor
- Eastern Mediterranean University
Rheumatoid Arthritis - Rheumatism
Application of Warm Water and Warm Salt Water to Patients With Rheumatoid Arthritis
This pretest-posttest randomized controlled study aimed to determine the effect of warm salt water and warm water bath applied to the hands and feet on pain, fatigue, sleep quality, and functional capacity in patients with…
- Trial name
- NCT05888220
- Testing
- warm salt water bath
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Acute Pain, Surgery
Auriculotherapy for Surgical Pain
The current opioid epidemic has led to a renewed interest in exploring non-pharmacological techniques to treat post-operative pain.
- Conditions
- Acute Pain, Surgery, Shoulder Pain
- Trial name
- NCT03860259
- Testing
- Auriculotherapy cryopuncture device without nitrogen gas, Auriculotherapy cryopuncture device with nitrogen gas
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jacques E. Chelly
Nerve Block, Pain, Postoperative
TAP vs. ESP Block for Gynecological Post Operative Pain
The goal of this double blind randomized controlled trial is to compare transversus abdominis plane block and erector spinae plane block in gynecological surgery patients.
- Trial name
- NCT06044779
- Testing
- Transversus Abdominis Plane Block using 0.25% Bupivacaine, Erector Spinae Plane Block using 0.25% Bupivacaine
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Padjadjaran
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