Clinical trials: Pain, completed
Opioid Dependence, Pain
The Effects of Minocycline in Opioid-maintained Patients
Opioids are the most commonly utilized pharmacological treatment for moderate to severe pain. However, their clinical value is hindered by the development of opioid-induced hyperalgesia (OIH).
- Trial name
- NCT02359006
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Yale University
Migraine, Migraine in Adolescence
Mindfulness-Based Intervention for Adolescents With Chronic Migraine
The goal of this study is to assess feasibility and acceptability of a mindfulness-based intervention adapted for adolescents with migraine to inform a future randomized trial assessing effects of the intervention on…
- Trial name
- NCT06414109
- Testing
- BREATHE-Migraine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Colorado, Denver
Pain
Is the Efficacy of Epidural Steroid Injections Related to the Different Volume Injections?
This study was aimed to investigate the impact of using different epidural volumes. Patients with acute discogenic pain were included in the study.
- Trial name
- NCT02343432
- Testing
- Triamcinolone, Epidural Volume, Bupivacaine
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Neslihan Uztüre
Effect of Progressive Relaxation Exercise
Progressive Relaxation Exercise on Pain, Anxiety and Patient Satisfaction
This single-center, prospective, randomized controlled trial was completed with a total of 70 patients, 35 in each of the intervention and control groups.
- Trial name
- NCT06871332
- Testing
- Progressive relaxation exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- TC Erciyes University
Hernia
Long-term Results After Endoscopic Total Extraperitoneal Repair of Recurrent Inguinal Hernia
Evaluation of long-term results for chronic pain and impairment of daily activities after endoscopic total extraperitoneal repair of recurrent inguinal hernia with inguinal pain questionnaire (IPQ).
- Trial name
- NCT00683098
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- St. Claraspital AG
Pain, Postoperative
Implementing Genomics in Practice (IGNITE): CYP2D6 Genotype-Guided Pain Management in Patients Undergoing Arthroplasty Surgery
This will be a randomized, open-labeled pilot pragmatic clinical trial. Patients undergoing arthroplasty surgery will be recruited from the University of Florida (UF) Health Gainesville and the Villages Orthopedic clinics for…
- Trial name
- NCT03534063
- Testing
- CYP2D6-guided opioid therapy
- Where
- 3 sites in United States
- Volunteers
- 260 people
- Sponsor
- University of Florida
Pain, Patient Satisfaction
Patient-controlled Sedation in Port Implantation (PACSPI-1)
The purpose of this prospective, observational study is to assess the feasibility of patient-controlled sedation (PCS) for implantation of subcutaneous venous ports (SVP).
- Trial name
- PACSPI-1 (NCT04631393)
- Testing
- Propofol Alfentanil
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Stefanie Seifert
Back Pain, Neuralgia
Evaluation of Spinal Cord Stimulation Pulse Rate On Clinical Outcomes
Clinical study to estimate the optimal frequency for stimulation of the spinal cord to achieve relief from back pain.
- Trial name
- PROCO (NCT02549183)
- Testing
- Boston Scientific PRECISION Spinal Cord Stimulator System
- Where
- 3 sites in United Kingdom
- Volunteers
- 22 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
Hemiplegic Shoulder Pain
Comparison of Effectiveness of Low Dose Laser and Transcutaneous Electrical Stimulation in Hemiplegic Shoulder
The primary aim of this study is to compare the efficacy of Transcutaneous Electrical Nerve Stimulation (TENS) and Low Level Laser Therapy (LLLT), which are analgesic modalities that play an important role in the treatment of…
- Trial name
- NCT07203222
- Testing
- Low Dose Laser, TENS, Conventional physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara Etlik City Hospital
Bariatric Surgery Candidate, Morbid Obesity
Erector Spinae Plane Block Versus Opioid Based General Anesthesia During Laparoscopic Bariatric Surgery
bilateral continuous erector spinae plane blockade may represent a valuable alternatives to thoracіc epidurals analgaesіa in treatment of thoracic neuropathic pain.
- Conditions
- Bariatric Surgery Candidate, Morbid Obesity, Visceral Pain
- Trial name
- NCT03798522
- Testing
- bilateral ultrasound guided erector spinae plane block, Nalbuphine
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dry Eye
Effect of Povidone-iodine 5% Vs 1% on the Ocular Surface in Intravitreal Injections of Anti-VEGF
Objective and subjective comparison between the use of povidone-iodine 1% vs 5% as antiseptic in patients that need anti-VEGF intravitreal injection
- Trial name
- anti-VEGF (NCT06710951)
- Testing
- Change of normal concentration of povidone-iodine 5% to 1%
- Where
- Mexico
- Volunteers
- 88 people
- Sponsor
- José Gerardo García Aguirre
Postoperative Pain, Obesity
Comparison of Two Magnesium Sulfate Protocols in Opioid-Free Anesthesia for Bariatric Surgery
This retrospective observational study aims to compare postoperative morphine consumption in patients undergoing bariatric surgery with opioid-free anesthesia (OFA) using two different intravenous magnesium sulfate administration…
- Conditions
- Postoperative Pain, Obesity, Bariatric Surgery, Opioid-free Anesthesia
- Trial name
- OFA-MG (NCT07077031)
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Hospital HM Nou Delfos
Laparoscopic Cholecystectomy, Postoperative Pain
Local Infiltration With Levobupivacaine During Laparoscopic Cholecystectomy
Randomized controlled trial on laparoscopic cholecystectomy. Interventional group: preincisional infiltration with levobupivacaine. Control group: no local infiltration.
- Conditions
- Laparoscopic Cholecystectomy, Postoperative Pain, Local Infiltration, Levobupivacaine
- Trial name
- NCT04697329
- Testing
- Preincisional infiltration with levobupivacaine
- Where
- Spain
- Volunteers
- 233 people
- Sponsor
- Hospital Universitario de Móstoles
Neuropathic Pain, Spinal Cord Injuries (SCI)
High-frequency Alternating Current Stimulation for Neurophatic Pain in Spinal Cord Injury
To investigate the safety and effectiveness of transcutaneous electrical stimulation with 40 kHz alternating currents combined with standard treatment compared to placebo electrical stimulation plus standard treatment for…
- Trial name
- NCT07359677
- Testing
- Active group 40 kHz
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Castilla-La Mancha
Pelvic Girdle Pain, Diastasis Recti and Weakness of the Linea Alba
The Association Between Pelvic Floor Muscle Function, Diastasis Recti and Postpartum Pelvic Girdle Pain - a Matched Case Control Study.
Background: Pregnancy-related pelvic girdle pain (PGP) can appear during pregnancy, directly after labour or can be delayed to 3 weeks postpartum.
- Conditions
- Pelvic Girdle Pain, Diastasis Recti and Weakness of the Linea Alba, Pelvic Floor Disorders
- Trial name
- NCT04757077
- Where
- Poland
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Żelazna Medical Centre, LLC
Chronic Pain
OXN PR Tablet 5/2.5 mg and20/10 mg PK Study in Chinese Moderate to Severe Chronic Non-malignant Patients
This is an open-label, randomized, single-dose, parallel group study. The objectives of this study are to assess pharmacokinetics of oxycodone and naloxone from oxycodone/naloxone (OXN) prolonged release (PR) tablet 5/2.5 mg (OXN…
- Trial name
- NCT02880475
- Testing
- OXN PR tablet
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Mundipharma (China) Pharmaceutical Co. Ltd
Chronic Neuropathic Pain
EEG Theta Band Rhythm in SCS
The investigators want to assess if reversal in EEG theta power during trial phase can serve as an objective marker for sustained clinical response, identifying true responders, and if the changes in EEG pattern during trial with…
- Trial name
- NCT07820657
- Testing
- Reversal in EEG Theta Power
- Where
- United Kingdom
- Volunteers
- 23 people
- Sponsor
- Walton Centre NHS Foundation Trust
Osteoarthritis, Knee
A Study To Investigate Whether PF-04457845 Is Effective In Treating Pain, Is Safe And Tolerable In Patients With Osteoarthritis Of The Knee
Inactivation of the FAAH (Fatty Acid Amide Hydrolase) enzyme has been shown to relieve pain and inflammation in animal studies. PF-04457845 has been shown to inactivate the FAAH enzyme in animals and healthy human volunteers.
- Trial name
- NCT00981357
- Testing
- PF-04457845, Naproxen
- Where
- 7 sites in United States, Canada and 1 more
- Volunteers
- 76 people
- Sponsor
- Pfizer
Rotator Cuff Injury
Rehabilitation After Rotator Cuff Repair
A new postoperative regimen with a new bandage technique after surgery results in a better shoulder function and quality of life after surgery - than traditional postoperative regimen with shoulder lock and abductor cushion.
- Trial name
- NCT02261701
- Testing
- Early mobilization, Post surgery shoulder lock
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Uppsala University
Low Back Pain
Blood Flow Restriction Training as a Targeted Intervention for Rowers With Back Pain.
The purpose of this graduate student research study is to compare the effects of low-load blood flow restriction training (LL-BFR) and heavy-load training (HLT) in high-volume rowers with mild low back pain or recurrent low back…
- Trial name
- NCT07130812
- Testing
- blood flow restriction, Heavy load resistance training
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
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