Clinical trials: Pain, completed
Back Pain, Neck Pain
Spine Pain INtervention to Enhance Care Quality And Reduce Expenditure
Low back and neck pain are among the leading causes of medical visits, lost productivity and disability. There is an urgent need to identify effective and efficient ways of helping subjects with acute spine pain while guiding…
- Trial name
- SPINE CARE (NCT03083886)
- Testing
- Identify, Coordinated, Enhanced (ICE) Decision Making + PCP led care, Individualized Postural Therapy (IPT) + PCP led care, Usual PCP led care
- Where
- 8 sites in United States
- Volunteers
- 3,087 people
- Sponsor
- Brigham and Women's Hospital
Hysteroscopy
Pericervical Analgesia Versus Analesia With Nitrous Oxide (N2O) in Outpatien Operative Hysteroscopy With Miniresector
This research will have the aim of evaluating and comparing the effectiveness of two methods (analgesia with nitrous oxide and pericervical analgesia, excluding the use of paracervical block due to the increased risk of…
- Trial name
- NCT06092541
- Testing
- Intervention Group: pericervical anesthesia, Nitroux Oxide anesthesia
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ospedale degli Infermi di Biella
Procedural Pain, Venipuncture
Leap Motion Controller for Pain During Venipuncture in Pediatrics
Venipuncture is the most frequent invasive procedure in hospitals and clinics. In the pediatric population this is very often associated with fear, anxiety, distress and enhanced perception of pain.
- Trial name
- LeapRCT (NCT05441241)
- Testing
- Leap Motion Controller, Traditional distraction techniques
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- IRCCS Burlo Garofolo
Stable Angina
Downstream Molecular Signals of P2Y12 Receptors in Hyporeactive Patients Under Clopidogrel Treatment A Possible Mechanism of HOTPR(High On-Treatment Platelet Reactivity)
The investigators designed the following experiment to observe the pattern of administration in vitro, which can be completely excluded liver enzyme cytochrome P450 metabolism under the influence and observe the relevant P2Y12…
- Trial name
- NCT03190005
- Testing
- clopidogrel
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Taipei City Hospital
Major Depressive Disorder
A Study in Depression and Associated Painful Physical Symptoms
The purpose of this study is to find out if 60 mg of duloxetine given once a day by mouth for 8 weeks to patients diagnosed with major depressive disorder, who also report associated painful physical symptoms, is better than…
- Trial name
- NCT01070329
- Testing
- Duloxetine
- Where
- 34 sites in United States, Puerto Rico
- Volunteers
- 527 people
- Sponsor
- Eli Lilly and Company
Healthy
Electrical Stimulation With Different Currents: the Effects on Force, Tolerance and Fatigue in Healthy Subjects
Muscle strength is the amount of force generated by muscle contraction. It could be measured with an isometric dynamometer. This is a validated tool that could be used to measure Maximal Voluntary Isometric Contraction (MVIC) and…
- Trial name
- NCT03340337
- Testing
- Neo-Russian, Aussie, RBS
- Where
- Argentina
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto Universitario de Ciencias de la Salud Fundación H.A. Barceló
Postoperative Pain, Postoperative Nausea and Vomiting
Effect of Steroids on Post-tonsillectomy Morbidities
This study aims to evaluate the effect of postoperative systemic rapid onset and short acting dexamethasone followed by a tapering dose of oral prednisolone on post-tonsillectomy morbidities.
- Trial name
- NCT02401529
- Testing
- IV dexamethasone, Oral prednisolone, Paracetamol
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Fahd General Hospital
Cancer
PAIN-LESS: Understanding and Alleviating Pain for Cancer Patients in Academic and Community Hospitals
This study will increase knowledge of patient preferences for pain treatments, and improve the ability to meet patients pain management needs.
- Trial name
- NCT02559375
- Testing
- Survey
- Where
- United States
- Volunteers
- 466 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Chronic Pain
Measuring Chronic Pain Impact: Measurement Enhancement for Chronic Pain
Many complementary and integrative health approaches have been shown to be effective for chronic pain and included in guidelines.
- Trial name
- NCT04426812
- Testing
- No intervention; just data collection
- Where
- United States
- Volunteers
- 11,146 people, healthy volunteers welcome
- Sponsor
- RAND
Fibromyalgia
Transcranial Direct Current Stimulation (tDCS) as Treatment Method for Pain in Fibromyalgia
The purpose of this study is to investigate Transcranial Direct Current Stimulation as treatment method for pain in fibromyalgia.
- Trial name
- NCT01598181
- Testing
- tDCS NeuroConn DC-stimulator plus
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- University Hospital of North Norway
Osteoarthritis of the Knee
Hydros and Hydros-TA Joint Therapy for Pain Associated With Knee Osteoarthritis
The purpose of this study is to evaluate the safety and efficacy of Hydros-TA Joint Therapy for relief of pain due to OA of the knee.
- Trial name
- NCT02022930
- Testing
- Hydros, Hydros-TA, Triamcinolone Acetonide
- Where
- 5 sites in Australia, Canada and 1 more
- Volunteers
- 510 people
- Sponsor
- Carbylan Therapeutics, Inc.
Facet Joint Pain
The Cervical Trident Study
This observational retrospective study evaluates the efficacy of RF with the three-tined expandable electrode needle compared to before treatment in the treatment of chronic cervical facet joint pain.
- Trial name
- NCT05353465
- Testing
- Radiofrequency denervation of the cervical facet joint
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Ospedale Regionale di Lugano
Migraine, Episodic Migraine
Study of Two Digital Therapeutics for the Prevention of Episodic Migraine
Randomized study of two digital therapeutics for the prevention of episodic migraine
- Conditions
- Migraine, Episodic Migraine, Headache, Headache, Migraine
- Trial name
- ReMMi-D (NCT05853900)
- Testing
- ReMMi-D Digital Therapeutic
- Where
- United States
- Volunteers
- 568 people
- Sponsor
- Click Therapeutics, Inc.
Knee Osteoarthritis, Knee Arthritis
Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Knee Arthroplasty
Effect of perineurial dexamethasone and dexmedetomidine on erector spinal plane block duration for knee arthroplasty
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Disease, Knee Pain Chronic
- Trial name
- NCT06470100
- Testing
- 0.9% Sodium Chloride Injection, Dexamethasone, Dexmedetomidine
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Low Back Pain
Implementation of a Best Practice Primary Health Care Model for Low Back Pain
POPULATION: Low back pain (LBP) is a major health problem commonly requiring health care. In Sweden, primary care professionals require an evidenced based model of care for LBP.
- Trial name
- BetterBack (NCT03147300)
- Testing
- Current routine practice, Multifaceted implementation of the BetterBack
- Where
- Sweden
- Volunteers
- 467 people
- Sponsor
- Linkoeping University
Irritable Bowel Syndrome
A Randomized Controlled Pilot Trial of Mesalazine in Patients With Irritable Bowel Syndrome
Emerging evidence indicates the presence of low-grade mucosal inflammation and its pathogenetic role in IBS. The aim of this pilot study is to provide that mesalazine treatment of IBS patients reduces low grade colonic…
- Trial name
- NCT00774007
- Testing
- mesalazine
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- SOFAR S.p.A.
Labor Pain, Labor Onset
The Effects of Breathing Exercises and Virtual Reality Applications During Pregnancy and Labor.
Aim and Objectives: The purpose of this study was to determine the effects of breathing exercises and virtual reality applications during pregnancy and labor on labor pain, duration, and birth satisfaction.
- Conditions
- Labor Pain, Labor Onset, Patient Satisfaction, Virtual Reality
- Trial name
- NCT05527236
- Testing
- Breathing Exercise, Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Semra Çevik, phD
Joint Pain, Knee Osteoarthritis
Efficacy and Safety of Celecoxib/Acetaminophen Versus Celecoxib for Diagnosed Osteoarthritis in Acute Exacerbation
This is a Phase III, longitudinal, multicenter, randomized, double-blind clinical trial designed to evaluate the efficacy and safety of a fixed-dose combination of celecoxib and acetaminophen compared to celecoxib monotherapy for…
- Conditions
- Joint Pain, Knee Osteoarthritis, Hip Osteoarthritis
- Trial name
- PRECEDENT (NCT06863636)
- Testing
- Celecoxib + Acetaminophen, Celecoxib
- Where
- Mexico
- Volunteers
- 231 people
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Superficial Cervical Block, Postoperative Pain
The Effect of Superficial Cervical Block Application on Postoperative Opioid Consumption in Patients Undergoing Anterior Cervical Discectomy Surgery
This randomized controlled trial aims to evaluate the effect of superficial cervical block on postoperative opioid consumption in patients undergoing anterior cervical discectomy surgery.
- Trial name
- NCT06755736
- Testing
- superficial cervical plexus block
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Medipol University
Mastectomy, Postoperative Pain
Comparison of Postoperative Analgesic Effectiveness of Superficial and Deep Serratus Plane Blocks for Mastectomy
Pain after breast surgery can be quite severe and can significantly affect quality of life. By successfully treating acute pain, it is aimed to prevent the formation of pain memory and to ensure that chronic pain never occurs.
- Conditions
- Mastectomy, Postoperative Pain, Analgesia
- Trial name
- NCT06438211
- Testing
- superficial or deep serratus anterior plane block for mastectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- TC Erciyes University
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