Clinical trials: Pain, completed
Laparoscopic Cholecystectomy, Optic Nerve Sheath Diameter Measurement
Effects of Bolus Versus Infusion Ketamine During Laparoscopic Cholecystectomy
This prospective, randomized, controlled study evaluated the effects of different ketamine administration strategies in adult patients undergoing elective laparoscopic cholecystectomy under general anesthesia.
- Conditions
- Laparoscopic Cholecystectomy, Optic Nerve Sheath Diameter Measurement, Ketamine, Postoperative Pain
- Trial name
- ketamine (NCT07900854)
- Testing
- ketamine bolus, ketamin infusion, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Pain, Acute Otitis Media
Study to Assess the Safety and Efficacy of Benzocaine for Pain Relief in Children Presenting With Acute Otitis Media
To assess the clinical safety and efficacy of the Benzocaine relative to placebo in pain relief associated with acute otitis media.
- Trial name
- NCT02092454
- Testing
- Benzocaine
- Where
- 3 sites in United States
- Volunteers
- 65 people
- Sponsor
- Otic Therapy, LLC
Endometriosis
Effects of Intravenous Lidocaine on Endometriosis Pain
We are doing this research study to find out if intravenous (in your vein, "IV") lidocaine can lessen pain from endometriosis. The U.S.
- Trial name
- NCT01968694
- Testing
- IV Lidocaine, IV diphenhydramine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Inflammatory Response, Radiculopathy
Inflammatory Markers in Lumbar Radicular Pain Treated With PRF and TFESI
This retrospective observational study aims to evaluate the predictive value of systemic inflammatory markers in determining treatment response in patients with lumbar radicular pain treated with a combination of pulsed…
- Conditions
- Inflammatory Response, Radiculopathy, Radiculopathy Lumbar, Chronic Pain
- Trial name
- NCT07495566
- Testing
- Lumbar Dorsal Root Ganglion Pulsed Radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 264 people
- Sponsor
- Ankara Etlik City Hospital
Healthy, Hyperalgesia
Influence of Genetics in Pain Sensitivity
The purpose of this study is to learn more about the role of genetics in pain sensitivity. Pain perception varies widely among individuals, and information gained from this trial may lead to better methods of preventing and…
- Conditions
- Healthy, Hyperalgesia, Pain
- Trial name
- NCT00001956
- Testing
- Blood draw, Oral surgery, Tissue biopsy
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Hemophilia
Resistance Training With Blood Flow Restriction in Hemophilia
The main objectives of this study are to evaluate safety and chronic effects of a low-load resistance exercise intervention (elbow flexions and extensions, and knee extensions) with blood flow restriction in people with…
- Trial name
- HemoBFR (NCT05568524)
- Testing
- BFRT, Control
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- University of Valencia
Rotator Cuff Tear, Postoperative Pain
Interscalene Block With and Without Liposomal Bupivacaine in Shoulder Surgery
The purpose of this study is to examine the difference in perioperative pain after shoulder surgery with a standard bupivacaine nerve block compared to liposomal bupivacaine enhanced nerve block alone in TSA and ARCR.
- Trial name
- NCT03728946
- Testing
- Liposomal Bupivacaine
- Where
- 6 sites in United States
- Volunteers
- 100 people
- Sponsor
- Orthopaedic & Neurosurgery Specialists
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)), Myocardial Infarction
Telerehabilitation in Coronary Heart Disease
Cardiovascular diseases are the main cause of death worldwide. Aerobic fitness is related to long-term survival and a reduction in mortality and recurrent nonfatal myocardial infarction in subjects with cardiovascular disease.
- Conditions
- Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)), Myocardial Infarction, Percutaneous Transluminal Cutting Balloon Angioplasty of Popliteal Vein Using Fluoroscopic Guidance
- Trial name
- TRiCH (NCT02047942)
- Testing
- Center-based cardiac rehabilitation, Home-based training with telemonitoring guidance
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- KU Leuven
Pain, Postoperative
Dipyrone Versus Acetaminophen in the Control of Postoperative Pain
Adequate postoperative pain management is challenging for practitioners despite recent advances in pain control techniques and analgesic agents.
- Trial name
- NCT00841841
- Testing
- dipyrone and acetaminophen
- Volunteers
- 30 people
- Sponsor
- University Center of Araraquara
Knee Osteoarthritis
Safety and Efficacy of Lorecivivint (SM04690) for the Treatment of Knee Osteoarthritis (STRIDES)
This phase 3 study was a multicenter, randomized, double-blind, placebo-controlled study of lorecivivint injected intra-articularly (IA) into the target (most painful) knee joint of moderately to severely symptomatic…
- Trial name
- NCT05603754
- Testing
- Lorecivivint
- Where
- 44 sites in United States
- Volunteers
- 499 people
- Sponsor
- Biosplice Therapeutics, Inc.
Knee Osteoarthritis
Ambulatory Continuous Adductor Canal Block to Facilitate Same Day Discharge Following Total Knee Arthroplasty: A Pilot Study
Patients scheduled to undergo total knee arthroplasty will receive motor sparing knee blocks with continuous adductor canal block along with multimodal analgesia started pre-operatively and continued into the postoperative…
- Trial name
- NCT02228759
- Testing
- Adductor canal block
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Patellofemoral Pain Syndrome
Early Intervention for Adolescents With Patellofemoral Pain Syndrome
Self-reported, unspecific knee pain is highly prevalent among adolescents. A large proportion of the unspecific knee pain can be attributed to Patellofemoral Pain Syndrome (PFPS). There are a number of treatment options for PFPS.
- Trial name
- NCT01438762
- Testing
- Patient information and education, Information, education and physiotherapy
- Where
- Denmark
- Volunteers
- 102 people
- Sponsor
- Mogens Berg Laursen
Osteoarthritis
Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Osteoarthritis
This study is being done to test the safety and efficacy of LY3016859 for the treatment of osteoarthritis pain. This trial is part of the chronic pain master protocol H0P-MC-CPMP (NCT05986292) which is a protocol to accelerate…
- Trial name
- NCT04456686
- Testing
- LY3016859
- Where
- 33 sites in United States, Puerto Rico
- Volunteers
- 117 people
- Sponsor
- Eli Lilly and Company
Pain, Postoperative, Endodontically Treated Teeth
Postoperative Pain Intensity Associated With the Use of Different Nickel Titanium Instrumentation Systems
In this study the effect of different engine-driven nickel titanium (Ni-Ti) instrumentation systems (OneShape, Revo S and WaveOne) on postoperative dental pain in patients with asymptomatic teeth after a single-appointment root…
- Trial name
- NCT03478241
- Testing
- Group 1: single file rotary motion, Group 2: multiple file rotary motion, Group 3: single file reciprocal motion
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Neuropathy, Painful, Chemotherapy-induced Peripheral Neuropathy
Lidocaine for Oxaliplatin-induced Neuropathy
Oxaliplatin-induced neuropathy is a major dose-limiting side effect in patients with colorectal cancer treated with the FOLFOX chemotherapy regimen.
- Conditions
- Neuropathy, Painful, Chemotherapy-induced Peripheral Neuropathy, Colorectal Cancer
- Trial name
- NCT03254394
- Testing
- Lidocaine Hydrochloride, FOLFOX regimen
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Washington University School of Medicine
Osteoarthritis of the Knee, Chronic Lower Back Pain
A Study to Assess the Analgesic Efficacy of ASP7962 in Patients With Pain Due to Osteoarthritis of the Knee
The purpose of the study is to evaluate the analgesic efficacy of ASP7962 relative to placebo. This study will also evaluate the efficacy of ASP7962 relative to placebo on pain on walking, function and stiffness; the time course…
- Trial name
- OAK (NCT02611466)
- Testing
- ASP7962, Naproxen
- Where
- 34 sites in Belgium, Czechia and 4 more
- Volunteers
- 215 people
- Sponsor
- Astellas Pharma Europe B.V.
Pain, Postoperative, Nerve Block
Paravertebral Blocks for Breast Cancer Surgery
This research project intends to look at the effect that a certain type of freezing injection, called a paravertebral block, has on the pain after an operation for breast cancer, the amount of pain relief that is needed and the…
- Trial name
- NCT01904266
- Testing
- GA + paravertebral block
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Alberta
Myelopathy Cervical, Kyphosis Post Surgical
Comparison Between C3-6 Laminoplasty and C3 Laminectomy With Cervical Laminoplasty
Investigators performed a prospective randomized controlled trial for comparing postoperative clinical and radiological outcomes between C3 laminectomy with laminoplasty and C3-6 laminoplasty.
- Conditions
- Myelopathy Cervical, Kyphosis Post Surgical, Neck Pain, Ossification of Posterior Longitudinal Ligament
- Trial name
- NCT05006495
- Testing
- C3 laminectomy, C3 laminoplasty
- Where
- South Korea
- Volunteers
- 126 people
- Sponsor
- Seoul National University Hospital
Neck Pain, Chronic Neck Pain
Effect of Added Load on Map-Based Proprioceptive Training in Chronic Neck Pain
The purpose of this study is to find out whether adding an external load to a map-based cervical proprioceptive training program provides additional benefit for people with chronic neck pain.
- Trial name
- NCT07900295
- Testing
- Weightless map-based proprioceptive training, Weighted map-based proprioceptive training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Musculoskeletal Pain
Students' Lifestyle Behaviour and Later Health Care Utilization Due to Musculoskeletal Pain
This study aims to assess whether there is an association between students' lifestyle behaviour, in terms of physical activity level, sleep duration, smoking status, alcohol consumption and use of cannabis and other illegal…
- Trial name
- NCT06157112
- Testing
- Lifestyle behaviour (exposure in a observational study)
- Where
- Norway
- Volunteers
- 50,054 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
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