Clinical trials: Pain, completed
Pain
Does Alkalinization Reduce Perceived Pain Levels During Sentinel Lymph Node Imaging?
Pain during nuclear medicine breast lymphnode detection procedures has been reported as high as 8.8/10. Using Sodium Bicarbonate to alkalinize the radio-pharmaceutical injection, pain can safely be reduced from 6.6/10 to 4.7/10…
- Trial name
- buffering SLN (NCT01660412)
- Testing
- Standard of Care First, ph Altered first
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Arkansas
Post-operative Pain Management, Hip Fracture Surgery
Comparison of Analgesic Efficacy of PENB Block with FICB in Post Operative Hip Fracture Patients
This study was done to evaluate two different interventions for postoperative pain control in patients undergoing hip surgeries. Fifty patients, divided in two equal groups, were included in the study.
- Trial name
- NCT05810012
- Testing
- PENG block, FICB Block
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Pain Medicine Department
Diabetic Neuropathy, Painful; Diabetic Neuropathies
Safety, Tolerability and Preliminary Efficacy of AZD5213 in Combination With Pregabalin in Subjects With PDN and Good Pain Reporting Ability
This is a 2-part study. In Part 1 of the study, subjects will undergo a pain reporting training program in which a painful stimulus will be applied to the subject's hand, and the subjects will be asked to report how painful the…
- Trial name
- NCT01928381
- Testing
- AZD5213 + pregabalin, pregabalin capsules
- Where
- 9 sites in United States
- Volunteers
- 150 people
- Sponsor
- AstraZeneca
Pain, Postoperative, Ketamine Adverse Reaction
Neuropsychiatric and Cardiovascular Side Effects in Ketamine Analgesic Infusions
Evaluation of neuropsychiatric and cardiovascular side effects of low dose ketamine analgesic infusion for postoperative pain
- Trial name
- NCT03525912
- Testing
- Ketamine
- Where
- Colombia
- Volunteers
- 101 people
- Sponsor
- Universidad de Antioquia
Total Shoulder Arthroplasty
Exparel for Total Shoulder Arthroplasty
The primary objective of this study is to determine if Exparel leads to better pain scores at 24, 48 and 72 hours after Total Shoulder Arthroplasty (TSA) compared to a pain pump.
- Trial name
- NCT04364867
- Testing
- Exparel, Pain Pump
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Norton Healthcare
Post-surgical Pain
Hydromorphone Hydrochloride Epidural Preemptive Analgesia for Postoperative Pain After Cesarean Section
Acute pain often occurs after cesarean section, which can lead to stress and inflammatory response in the body, which will not only affect the postpartum recovery speed of the puerpera, but also inhibit the secretion of prolactin…
- Trial name
- HHEPA (NCT06823180)
- Testing
- Hydromorphone hydrochloride low dose, Hydromorphone hydrochloride high dose, 0.9% sodium chloride
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Liquan Liang
Hypothermia
Study to Determine the Effects of Pre-warming on OR Patient Temperatures and Surgical Outcomes
The application of active warming to patients whether awake or under general anesthesia has been proven safe in numerous studies and it is common practice to use warmers.
- Trial name
- NCT02177903
- Testing
- Bair Paws Patient Adjustable Warming System
- Where
- Canada
- Volunteers
- 220 people
- Sponsor
- Solventum US LLC
Post Operative Pain
The Efficacy of SPSIPB on Postoperative Pain and Analgesic Consumption in Patients Undergoing VATS
The aim of this study is to investigate the postoperative analgesic efficacy of SPSIPB and its effect on opioid consumption in patients undergoing video-assisted thoracoscopic surgery (VATS).
- Trial name
- NCT05901103
- Testing
- Serratus posterior superior intercostal plane block (SPSIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Cumhuriyet University
Muscle Soreness
Topical CBD's Effects on Soreness and Performance
Exercise-induced muscle damage (EIMD) results from unaccustomed exercise and can lead to delayed onset muscle soreness (DOMS). Impairments associated with EIMD and DOMS can result in moderate-to-severe discomfort and hindered…
- Trial name
- NCT06320327
- Testing
- Cannabidiol cream
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Joseph Pastina
Low Back Pain
Are Acceptance and Commitment Related to Treatment Response in Chronic Low Back Pain
The main objective of this study is to evaluate whether acceptance (measured by the AAQ-II questionnaire) is prognostic of algo-functional changes measured by the Oswestry Disability Index, ODI) at 6 months.
- Trial name
- COP-PAIN (NCT02426970)
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Acute Pain, Surgery
Comparison of Epidural and TAP Block in Abdominal Surgery
This study will compare the infiltrative transversusabdominis plane (TAP) block with liposomal bupivacaine to epidural analgesia (EA) in major abdominal surgery .
- Conditions
- Acute Pain, Surgery, Regional Anesthesia
- Trial name
- NCT01848951
- Testing
- Epidural, TAP Block
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Nebraska
Procedural Pain, Acute Pain
Fan-Assisted Local Cooling for Pain During Intravenous Cannulation in Adults
Inserting an intravenous (IV) cannula is one of the most frequently performed procedures in clinical practice, and it is commonly experienced as painful. Before the needle is inserted, the skin is routinely cleaned with alcohol.
- Conditions
- Procedural Pain, Acute Pain, Peripheral Intravenous Catheterization
- Trial name
- NCT07740837
- Testing
- Fan-assisted local cooling, Standard alcohol skin preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Antalya Health Sciences University
Breast Cancer, Recurrent Breast Cancer
Acupuncture in Treating Women With Stage I, Stage II, or Stage III Breast Cancer With Aromatase Inhibitor-Related Joint Pain
RATIONALE: Acupuncture may help relieve moderate or severe joint pain caused by aromatase inhibitors. PURPOSE: This randomized phase II trial is studying acupuncture in treating women with stage I, stage II, or stage III breast…
- Conditions
- Breast Cancer, Recurrent Breast Cancer, Stage I Breast Cancer, Stage II Breast Cancer
- Trial name
- NCT01013337
- Testing
- acupuncture therapy
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Submucosal Resection of the Nasal Septum (SMR)
Four vs. Ten Local Anesthetic Injections for SMR
Submucosal resection of the nasal septum (SMR) could be performed under local anesthetic infiltration performed through ten injections in addition to general anesthesia which was associated with less postoperative pain and…
- Trial name
- NCT02463370
- Testing
- suprazygomatic maxillary area infiltration, non-suprazygomatic maxillary area infiltration
- Where
- Lebanon
- Volunteers
- 120 people
- Sponsor
- Makassed General Hospital
Postoperative Pain
Comparison of the Efficacy of PENG Block in Combination With LFCN Block and Wound Infiltration
The ultrasound-guided approach for the blockade of articular branches of femoral and obturator nerves, pericapsular nerve group (PENG) block, is an effective method for postoperative analgesia in hip surgeries.
- Trial name
- NCT04681222
- Testing
- LFCN, Wound infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Derince Training and Research Hospital
Post-operative Pain
Open Thyroid Surgery With Pillow Versus no Pillow for Better Post-operative Outcomes
Primary: To compare the post-operative pain in patients with neck extension and without neck extension. Secondary: To determine the benefit of neck exposure and peri-operative complications, which include duration of operation…
- Trial name
- NCT01620151
- Testing
- Extended neck with standard support or pillow
- Where
- 2 sites in Hong Kong
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Low Back Pain
The Effectiveness of Wet Cupping on Persistent Non-specific Low Back Pain
The hypothesis of this study is that the improvement of Numeric Rating Scale (NRS) for Pain at the end of the study will be greater in the Wet Cupping Treatment group than in the Waiting Control group.
- Trial name
- NCT00925951
- Testing
- Wet Cupping, Acetaminophen
- Where
- South Korea
- Volunteers
- 37 people
- Sponsor
- Korea Institute of Oriental Medicine
Cancer, Cancer Pain
Effect of Music on Pain and Anxiety in Palliative Cancer Patients
Background: Cancer patients receiving palliative care often endure a variety of distressing symptoms, most notably pain and anxiety.
- Conditions
- Cancer, Cancer Pain, Palliative Care, Anxiety
- Trial name
- NCT07262151
- Testing
- Music Application, Procedures for the Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Karamanoğlu Mehmetbey University
Gut Health
Effectiveness of a Butyrate Formulation and Butyrate + Polyphenol Formulation on Gut Health, Permeability and Associated Symptoms
The purpose of this study is the assess the effectiveness and safety of a Butyrate formulation and a Butyrate + Polyphenol formulation on gut health, permeability and associated symptoms
- Trial name
- NCT06419231
- Testing
- Butyrate Formulation, Butyrate + Polyphenol Formulation
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.
Chest Pain, Acute Coronary Syndrome
Diagnostic Accuracy of Multislice CT Angiography for Acute Chest Pain
The ACUTE CT trial is designed to test whether the assessment of chest structures by high-resolution multislice computed tomography (CT) provides equivalent diagnostic accuracy for patient with acute chest pain or other potential…
- Conditions
- Chest Pain, Acute Coronary Syndrome, Pulmonary Embolism, Aortic Dissection
- Trial name
- ACUTE CT (NCT00855231)
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Washington
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