Clinical trials: Pain Intervention
Symptomatic Irreversible Pulpitis
Vital Pulp Therapy Versus Root Canal Treatment for Irreversible Pulpitis With Incipient Apical Periodontitis Diagnosed Using Artificial Intelligence This Keeps: the Main Intervention (Vital Pulp Therapy) the Comparison (Root Canal Treatment) the Condition (Irreversible Pulpitis With Incipient Apic
This study evaluates postoperative pain and treatment outcomes following vital pulp therapy and root canal treatment in patients with symptomatic teeth.
- Trial name
- NCT07549620
- Testing
- Vital Pulp Therapy, Root Canal Treatment
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Ain Shams University
Degenerative Lumbar Spine Causing Back and/or Leg Pain, Lumbar Spine Degeneration
A Prospective, Multicenter Observational Study on MAST™ (Minimal Access Spinal Technologies) Fusion Procedures for the Treatment of the Degenerative Lumbar Spine
The aim of the study is to observe and document surgical practice and evaluate patients' outcomes following a MAST™ single or double level instrumented fusion procedure using PLIF (Posterior Lumbar Interbody Fusion) or TLIF…
- Trial name
- MASTERS-D (NCT01143324)
- Testing
- MAST™ procedure
- Where
- 19 sites in Austria, Belgium and 12 more
- Volunteers
- 255 people
- Sponsor
- Medtronic Spinal and Biologics
Endometriosis, Endometriosis (Diagnosis)
Effect of Fish-Derived Lipids in Women With Endometriosis
Endometriosis is a chronic inflammatory gynecological disease that may be associated with pelvic pain, painful menstruation, reduced quality of life, impaired daily functioning, and changes in nutritional and metabolic health.
- Trial name
- fish-endo (NCT07800442)
- Testing
- Fish-derived lipid supplementation, Diet based on the Healthy Eating Plate recommendations
- Where
- Poland
- Volunteers
- 46 people
- Sponsor
- Angelika Bogusz
Chronic Pain
VETERANS AFFAIRS AUGUSTA
Chronic pain is a prevalent and debilitating condition among Veterans, often accompanied by depression, anxiety, sleep disturbances, and social isolation.
- Trial name
- NCT07776600
- Testing
- My AI Companion
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Companion IQ, Inc
Cancer
Digital Intervention for Symptom Management in Cancer and Opioid Sparing Using Virtual Reality (DISCOVR) Study
Patients living with cancer commonly have chronic pain due to the disease or to cancer treatments. Virtual reality, a new technology that immerses the user in pleasant, diverting, and exciting virtual environments, may lower…
- Trial name
- DISCOVR (NCT07228377)
- Testing
- virtual reality pain therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medstar Health Research Institute
Complex Regional Pain Syndrome Type I of the Upper Limb
Effects of Repetitive Electric Sensory Stimulation (RSS) as Intervention in Complex-regional-pain-syndrome Type I (CRPS)
The purpose of this study is to test a specific nerve stimulation protocol as therapeutic option in patients diagnosed with CRPS (complex regional pain syndrome) of the upper extremity.
- Trial name
- NCT01915329
- Testing
- RSS (repetitive sensory stimulation)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Ruhr University of Bochum
Burn Patients, Pain Management
Comfort Communication Model Intervention for Burn Pain and Pain Anxiety
This single-center, randomized controlled trial will evaluate the effect of a nursing intervention based on the COMFORT Communication Model on procedural pain and burn-specific pain anxiety in adult outpatient burn patients…
- Conditions
- Burn Patients, Pain Management, Nursing Interventions
- Trial name
- NCT07385339
- Testing
- Comfort Communication Model
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Baskent University
Neck Pain, Pain in Arm, Unspecified
Manual Cervical Distraction: Measuring Chiropractic Delivery for Neck Pain Clinical Trial
The purpose of the Manual Cervical Distraction: Measuring Chiropractic Delivery for Neck Pain Clinical Trial is to examine the patient-centered clinical and biomechanical outcomes, doctor treatment delivery, and believability…
- Trial name
- MCD (NCT01765751)
- Testing
- Manual Cervical Distraction
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Palmer College of Chiropractic
Chronic Low-back Pain, Degenerative Disc Disease
Postmarket Clinical Follow-Up Study on Arcadius XP L® Interbody Fusion Device
The purpose of this study is to collect clinical and radiological mid-term (min. 1 year) data on the ArcadiusXP L® lumbar stand-alone cage in a post-market clinical follow-up study (PMCF) limited to 60 patients.
- Conditions
- Chronic Low-back Pain, Degenerative Disc Disease, Spondylolysis Lumbar, Postdiscectomy Syndrome
- Trial name
- ARREST (NCT05944081)
- Testing
- ArcadiusXP L® Interbody Fusion System
- Where
- 3 sites in Germany
- Sponsor
- Aesculap AG
Coronary Artery Disease
FAME II - Fractional Flow Reserve (FFR) Guided Percutaneous Coronary Intervention (PCI) Plus Optimal Medical Treatment (OMT) Verses OMT
The overall purpose of the FAME II trial is to compare the clinical outcomes, safety and cost-effectiveness of FFR-guided PCI plus optimal medical treatment (OMT) versus OMT alone in patients with stable coronary artery disease.
- Trial name
- NCT01132495
- Testing
- Stenting plus OMT, OMT, Standard of care
- Where
- 29 sites in United States, Belgium and 11 more
- Volunteers
- 1,170 people
- Sponsor
- Abbott Medical Devices
Coronary Artery Disease
Functional Assessment by Virtual Online Reconstruction. The FAVOR III Europe Trial
Quantitative Flow Ratio (QFR) is a novel method for evaluating the functional significance of coronary stenosis. QFR is estimated based on two angiographic projections.
- Trial name
- NCT03729739
- Testing
- QFR-based diagnostic strategy, FFR-based diagnostic strategy
- Where
- 35 sites in Denmark, France and 9 more
- Volunteers
- 2,001 people
- Sponsor
- Aarhus University Hospital Skejby
Peripheral Vascular Disease
Lower Extremity Regional Anesthesia and Infrainguinal Bypass Grafting
In this investigation, the investigators will attempt to demonstrate that patients who have received nerve blocks (regional anesthesia) prior to open surgical vascular bypass of the lower extremities (infrainguinal bypass…
- Trial name
- NCT01803165
- Testing
- Single shot femoral and sciatic nerve block
- Sponsor
- University of Nebraska
Pain
iMpact of therapeUtic Live muSic on Pain and Distress Levels During Interventions in the paediatriC Emergency Department
The Emergency Department (ED) can be stressful and traumatic, especially for children and young people, and the clinical environment can be a frightening, unfamiliar space, which adds to an already anxious experience.
- Trial name
- Music:ED (NCT03956667)
- Testing
- Live Music
- Where
- United Kingdom
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Alder Hey Children's NHS Foundation Trust
Non-specific Low Back Pain
Effect of Reassuring Information on Danish Workers Who Experience Low Back Pain in the Following Year.
RCT study of the effect of an educational-based intervention on low back pain-related outcomes concerning beliefs and behaviour.
- Trial name
- VRRPF (NCT01918228)
- Testing
- Talks about what science says about LBP
- Where
- Denmark
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Procedural Pain, Child, Only
Effect of Acupressure on Interventional Pain in Infants
This study will be conducted to investigate the effect of acupressure, to be applied to the GallBladder (GB) 31 "Fengshi" acupuncture point before the vaccinations, on interventional pain caused by the vaccinations in infants.
- Trial name
- NCT05166551
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Fibromyalgia Syndrome
Osteopathic Medicine in Fibromyalgia Syndrome
The purpose of this study is to evaluate the analgesic effects of a 6 weeks osteopathic treatment on patients with fibromyalgia.
- Trial name
- FIBROPATHIC (NCT02343237)
- Testing
- Osteopathic treatment, Factitious osteopathic treatment
- Where
- France
- Volunteers
- 101 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myocardial Infarction, Percutaneous Coronary Intervention
Text Message Intervention to Improve Cardiac Rehab Participation
Cardiac rehabilitation (CR) is strongly recommended for patients with coronary heart disease. However, patient enrollment and completion of cardiac rehabilitation is low.
- Conditions
- Myocardial Infarction, Percutaneous Coronary Intervention, Coronary Artery Bypass Surgery, Heart Valve Repair or Replacement
- Trial name
- NCT03346278
- Testing
- Text Messaging Intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Washington
Neck Pain
Cervical Mobilization vs. Standard Physical Therapy for Chronic Neck Pain
Neck pain is a common problem in our society, accounting for 20% of all chiropractic visits. Physical therapy interventions for chronic neck pain have been chosen based on the patient's symptoms and examination findings.
- Trial name
- NCT01092715
- Testing
- Spinal mobilization, Massage, Neck exercises
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Mayo Clinic
Arthritis
The Effect of Music Therapy Intervention on Pain and Anxiety in Adult Patients Undergoing Total Shoulder Arthroplasty
The purpose of this study is to determine if music therapy interventions as adjunct to standard surgical care reduces pre- and post-operative pain and anxiety in patients undergoing total shoulder arthroplasty as compared with…
- Trial name
- NCT02692768
- Testing
- Live Music Therapy, Recorded Music Therapy, Control
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- April Armstrong
Spinal Cord Injuries, Neuropathic Pain
Virtual Walking Intervention for Neuropathic Pain in Spinal Cord Injury
The purpose of this study is to determine if playing a virtual reality walking game can help improve neuropathic pain in adults with chronic spinal cord injury.
- Trial name
- VRWalk (NCT05005026)
- Testing
- VR Game 1, VR Game 2
- Where
- 3 sites in United States, Australia
- Volunteers
- 250 people
- Sponsor
- Texas A&M University