Clinical trials: Pain Management
Pain Management
BreEStim in Managing Neuropathic Pain After Spinal Cord Injury (SCI)
The purpose of this study is to compare the effectiveness of innovative intervention of breathing controlled electrical stimulation (BreEStim) and sham BreEStim and Transcutaneous Electrical Nerve Stimulation (TENS) in management…
- Trial name
- NCT07659743
- Testing
- Active BreEStim Treatment, The TENS Treatment
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pain Management
Hypnosis Antalgia Emergency Stitching
Pain is one of the most common reasons patients seek care in emergency departments. Managing pain effectively is an important part of emergency care because it can improve patients' comfort and overall experience.
- Trial name
- HYPNAUS (NCT07872891)
- Testing
- hypnotic guidance
- Volunteers
- 134 people
- Sponsor
- University Hospital, Angers
Pain Management, Nurse
The Effect of Pain Management Education Program on Pain Management Self-Efficacy Among Nurses Caring for Palliative Care Patients: A Quasi-Experimental Study
The goal of this quasi-experimental research designed as a single-group pre-test post-test model is to evaluate the effect of an educational intervention aimed at improving the pain management self-efficacy of nurses providing…
- Conditions
- Pain Management, Nurse, Self Efficacy, Palliative Care
- Trial name
- P-EASE (NCT07685665)
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Pain Management
Analgesic Efficacy of Ultrasound-Guided Deep Iliacus Plane Block in Patients Undergoing Hip Fracture Surgery
Hip fracture surgery is commonly associated with moderate to severe postoperative pain, which may delay mobilization and increase the need for opioid analgesics.
- Trial name
- NCT07716540
- Testing
- Ultrasound-Guided Deep Iliacus Plane Block With Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Total Knee Arthroplasty (TKA), Total Knee Arthroplasty \(TKA\)
Suzetrigine in TKA
Total knee replacements are among the most common and painful orthopedic procedures performed worldwide, often requiring intensive analgesia to support early ambulation and recovery.
- Conditions
- Total Knee Arthroplasty (TKA), Total Knee Arthroplasty \(TKA\), Total Knee Replacement, Total Knee Replacement Surgery
- Trial name
- NCT07864896
- Testing
- Suzetrigine
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Surgical, Anxiety
Virtual Reality Therapy to Improve Arthroplasty Outcomes
Virtual reality (VR) has recently emerged as a non-medication-based method to manage anxiety. The patient wears a VR headset and is offered an immersive environment with hypnotic components with sound and imagery in a 3D…
- Conditions
- Surgical, Anxiety, Pain Management, Joint (Knee or Hip Replacement)
- Trial name
- VROOM (NCT07872670)
- Testing
- Virtual Reality Headset, Blood Samples, Questionnaires
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- NHS Highland Research, Development and Innovation Organisation
Postsurgical Pain Management, Postsurgical Pain, Chronic
An Artificial Intelligence Driven Approach to Optimize Patient Selection for a Transitional Pain Service
The goal of this clinical trial is to learn whether a pain-management program called a Transitional Pain Service can help prevent long-term pain and reduce opioid needs after surgery in adult surgical patients who may be at…
- Conditions
- Postsurgical Pain Management, Postsurgical Pain, Chronic, Opioid Use After Surgery
- Trial name
- TPS-Select (NCT07296770)
- Testing
- TPS-Select, Pharmacologic Pain Management, Interventional Pain Procedures
- Where
- United States
- Volunteers
- 474 people
- Sponsor
- University of California, San Francisco
Low Level Laser Therapy, Healthy
Effect of GaAlAs 940 Laser on Pain and Wound Healing After Free Gingival Graft
This randomized controlled clinical trial aims to evaluate the biomodulatory effects of a 940-nm GaAlAs diode laser on postoperative pain control and wound healing at the palatal donor site following free gingival graft…
- Conditions
- Low Level Laser Therapy, Healthy, Postoperative Pain Management, Wound Healing
- Trial name
- NCT07308912
- Testing
- 940 nm GaAlAs diode laser, palatal stent
- Where
- Vietnam
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Anterior Cruciate Ligament Reconstruction, Pain Management
Comparison of Analgesic Effects of ACB Versus ACB Combined With BiFeS Block in ACL Reconstruction Surgery
Anterior cruciate ligament (ACL) reconstruction is commonly associated with moderate to severe postoperative pain, particularly during the early postoperative period and rehabilitation.
- Trial name
- NCT07859397
- Testing
- Adductor Canal Block, BiFeS Block
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Ankara Etlik City Hospital
Artroscopic Surgery, Pain Management
Suzetrigine for Analgesiain Arthroscopic Rotator Cuff Repair
The goal of this prospective is to determinate if Suzetrigine decreased de use of opioids in patients that undergo an arthroscopic rotator cuff repair.
- Conditions
- Artroscopic Surgery, Pain Management, Pain After Shoulder Surgery, Opioid Consumption
- Trial name
- SOAR (NCT07866638)
- Testing
- Suzetrigine (Journavx), Standard multimodal analgesia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Rheumatological Injection, Pain Management
The Value of Standardized Respiratory Rate Monitoring Exercises During Rheumatological Injection Procedures
The goal of this clinical trial is to demonstrate the non-inferiority of standardized breathing control exercises on perceived pain during rheumatological injections procedures compared to standard care consisting of the addition…
- Conditions
- Rheumatological Injection, Pain Management, Respiratory Monitoring
- Trial name
- Respi-IR (NCT07172984)
- Testing
- Anesthesia, breathing group
- Where
- France
- Volunteers
- 136 people
- Sponsor
- Centre Hospitalier Metropole Savoie
Pain Management
A Clinical Trial of MK-6916 in Participants With Pain After Bunion Removal Surgery (MK-6916-007)
Researchers are looking for new treatments for pain. While there are many approved treatments for pain, the treatments do not work well for everyone. People can also become addicted to certain pain medicines.
- Trial name
- NCT07862595
- Testing
- MK-6916, Hydrocodone/acetaminophen (HB/APAP), Rescue Medication
- Volunteers
- 380 people
- Sponsor
- Merck Sharp & Dohme LLC
Prostate Cancer, Pain Management
The Influence of Music on perceiVed paIn and leVels of Anxiety whiLe unDergoing transperIneal Prostate Biopsy: the VIVALDI Trial
Prostate biopsy is the key examination for the histological diagnosis of prostate cancer. This procedure can be performed via the transrectal (TR) or transperineal (TP) approach.
- Trial name
- VIVALDI (NCT07234097)
- Testing
- Music intervention
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Multiple Sclerosis, Pilates Exercise
The Effect of Remotely Delivered Pilates on Physical , and Psychological Outcomes in Individuals With Multiple Sclerosis
Objectives Objective 1: To determine the effects of a 16-week remotely delivered Pilates intervention on walking endurance, walking speed, balance, fatigue, and pain compared to a waitlist control group in individuals with MS.
- Conditions
- Multiple Sclerosis, Pilates Exercise, Walking, Balance
- Trial name
- MS (NCT07504120)
- Testing
- Pilates
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Illinois at Chicago
Pain Management, C Section
Pain After Scheduled Cesarean Delivery: Spinal Morphine With or Without Levobupivacaine Wound Infiltration
The goal of this observational study is to learn whether injecting a numbing medicine (levobupivacaine, a local anesthetic) into the surgical wound at the end of a cesarean delivery improves pain control in women who also receive…
- Conditions
- Pain Management, C Section, Obstetric Pain, Levobupivacaine
- Trial name
- LEVO-CS (NCT07859956)
- Testing
- Levobupivacaine, Intrathecal Morphine
- Where
- Colombia
- Volunteers
- 336 people
- Sponsor
- Fundación Santa Fe de Bogota
Knee Osteoarthritis, Postoperative Pain Management
Effect of iPACK and BiFeS Blocks on Quality of Recovery After Total Knee Arthroplasty
This prospective, randomized, double-blind clinical trial aims to compare the effects of two different posterior knee analgesia techniques-iPACK block (Interspace Between the Popliteal Artery and the Capsule of the posterior…
- Conditions
- Knee Osteoarthritis, Postoperative Pain Management, Total Knee Arthroplasty
- Trial name
- BiFeS-TKA (NCT07248072)
- Testing
- Adductor Canal Block (ACB) Only, IPACK block, BiFeS Block
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Ataturk University
Pain After Total Knee Arthroplasty, Pain Management
Combined Distal Femoral Nerve Block for Pain Control After Knee Replacement
The goal of this clinical trial is to see whether a combined distal femoral nerve block improves pain relief after total knee replacement in adults having planned surgery.
- Trial name
- FEM-COMB (NCT07629388)
- Testing
- Combined distal femoral nerve block, Saphenous nerve block alone, Standard perioperative care in both groups
- Where
- France
- Volunteers
- 240 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Hormone Therapy-induced Arthralgia, Phytotherapy
Evaluation of the Efficacy and Acceptability of a Phytotherapy Combining Devil's Claw, Blackcurrant and Meadowsweet for the Management of Aromatase Inhibitor-induced Arthralgia in Patients Treated for Localized Breast Cancer in the Adjuvant Setting
Adjuvant hormonotherapy is a cornerstone of treatment for localized hormone receptor-positive (HR+) breast cancer, accounting for approximately 80% of patients.
- Conditions
- Hormone Therapy-induced Arthralgia, Phytotherapy, Symptom Management, Adjuvant Treatment
- Trial name
- ERABLE (NCT07859319)
- Testing
- Phytotherapy Dietary Supplement (Harpagophytum, Meadowsweet, and Blackcurrant), Patient Experience Questionnaire
- Where
- 3 sites in France
- Volunteers
- 105 people
- Sponsor
- Hospices Civils de Lyon
Burn Patients, Pain Management
Comfort Communication Model Intervention for Burn Pain and Pain Anxiety
This single-center, randomized controlled trial will evaluate the effect of a nursing intervention based on the COMFORT Communication Model on procedural pain and burn-specific pain anxiety in adult outpatient burn patients…
- Conditions
- Burn Patients, Pain Management, Nursing Interventions
- Trial name
- NCT07385339
- Testing
- Comfort Communication Model
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Baskent University
Pain, Fear
The Effect of Buzzy® and a Stress Ball on Reducing Pain and Fear During Peripheral Intravenous Cannulation in Children
This study aims to compare the effects of Buzzy®, a device that applies cold and vibration, and a stress ball on pain and fear during intravenous catheter insertion in children aged 7-12 years.
- Conditions
- Pain, Fear, Pain Management
- Trial name
- NCT07851909
- Testing
- Buzzy, Stress Ball
- Where
- Turkey (Türkiye)
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Akdeniz University