Clinical trials: Pain Management, completed
Post-operative Pain, Acute
Adductor Canal Blocks With Bupivacaine and Magnesium After Same-day Discharge Total Knee Arthroplasty Improve Post-operative Pain Relief and Decrease Opioid Consumption: a Prospective Randomized Controlled Trial
The purpose of this study is to determine whether the addition of magnesium to bupivacaine for the post-operative adductor canal blocks (ACB) can decrease opioid consumption and improve pain management for patients after same-day…
- Trial name
- NCT05004636
- Testing
- Adding Magnesium as an adjuvant to the adductor canal Block (ACB) for same-day discharge total knee arthroplasty
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Wayne State University
Neck Pain, Cervical Radiculopathy
Paramedian CESI vs Selective Nerve Root PRF for Lower Cervical Radicular Pain
This study aims to compare the efficacy of ultrasound-guided selective cervical nerve root pulsed radiofrequency (PRF) versus fluoroscopy-guided paramedian cervical epidural steroid administration (CESI) for the treatment of…
- Trial name
- NCT05950321
- Testing
- Paramedian cervical epidural steroid injection, Selective nerve root pulsed radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Musculoskeletal Pain, Chronic Pain
N-of-1 Trials Using mHealth in Chronic Pain
Chronic musculoskeletal pain is an important problem, and treatments are often prescribed in a "trial and error" fashion. Clinicians prescribe a treatment to a patient and then wait and see if the treatment is successful.
- Trial name
- PREEMPT (NCT02116621)
- Testing
- Trialist Intervention, smartphone
- Where
- 2 sites in United States
- Volunteers
- 215 people
- Sponsor
- University of California, Davis
Thyroid Goiter, Thyroid Nodule
Analgesia for Thyroidectomy Using Bilateral Superficial Cervical Plexus Block With Bupivacaine Only or Adding Ketorolac to it.
Thyroidectomy is considered a common operation with moderate to severe postoperative pain in some patients. Patients are divided into two groups.
- Trial name
- NCT05180214
- Testing
- Bupivacain, Ketorolac
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Sohag University
Fall Patients, Pain
Physiotherapy in Emergency Department: a Service Analysis From a French Hospital
The skills of physiotherapists have been employed to enhance access to optimal care in Emergency Departments (ED). No study has yet been conducted on the practices in France.
- Conditions
- Fall Patients, Pain, Sprains, Respiratory Insufficiency
- Trial name
- NCT06528899
- Testing
- Physical Therapy
- Where
- 2 sites in France
- Volunteers
- 461 people
- Sponsor
- Université de Nantes
Catheterization
Effect of Thermomechanical Stimulation Device and Virtual Reality Glasses During Peripheral Intravenous Catheterization
The study was conducted as a randomized controlled experimental study to determine the effect of Thermomechanical Stimulation Device (Buzzy®) and Virtual Reality Goggles (VRG) applied during peripheral intravenous catheterization…
- Trial name
- NCT05422287
- Testing
- Virtual Reality Glasses, Thermomechanical Stimulation Device
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Ankara Yildirim Beyazıt University
Postoperative Pain
Patient-Driven Analgesic Protocol Selection for Post-Cesarean Pain Management
The ability to predict pain and then apply modified treatment protocols has been limited. Current practice is for physicians to select standard post-operative pain treatment protocols without patient consultation.
- Trial name
- NCT02605187
- Testing
- No choice given, Choice given, Ibuprofen
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Stanford University
Injections, Spinal, Cancer
Place of Intrathecal Analgesia to Improve the Quality of Life of Painful Cancer Patients
The intrathecal analgesia is a recommended technic to treat persistent pain in cancer patient but little used, whose the technical conditions require hospital multidisciplinary expertise and coordination associated to a link…
- Trial name
- QUALITHEC01 (NCT04388449)
- Where
- 3 sites in France
- Volunteers
- 24 people
- Sponsor
- Institut Cancerologie de l'Ouest
Labor, Epidural Analgesia
Pulse Pressure Variability With Position Before EPIdural Analgesia
Fetal heart rate abnormalities are common. Miller et al. have demonstrated that new onset fetal heart rate abnormalities after initial labor epidural dosing occur more frequently in women with a low admission pulse pressure than…
- Trial name
- PP-PERI (NCT03126136)
- Testing
- Nicom (TM)
- Where
- 4 sites in France
- Volunteers
- 1 people
- Sponsor
- Hopital Foch
Labor Pain
Intrathecal Hydromorphone for Labor Analgesia
This study will investigate the dose of hydromorphone which will relieve the pain of women in labor when delivered directly in the area around the spinal cord (i.e., intrathecal injection).
- Trial name
- NCT01598506
- Testing
- Hydromorphone
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Emory University
Adductor Canal Block, Postop Analgesia for Knee
Adductor Canal Block Ultrasound Anatomy in Volunteers
There has been dispute about the location at which the adductor canal block should be performed (3-6). Two Common approaches have been used for ultrasound guided adductor canal blocks with the 'point of entry' being: 1.
- Trial name
- NCT03008564
- Testing
- Ultrasound scanning of the lower limb in volunteers
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Temporomandibular Joint Disorders
Complementary Medicine Approaches to TMD Pain Management
This study will determine whether selected complementary approaches to temporomandibular joint (TMJ) pain management-acupuncture are as effective as usual care.
- Trial name
- NCT00010621
- Testing
- Acupuncture, chiropractic therapy, bodywork therapy
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Headache, Intranasal Ketamine
"THINK Trial: Treatment of Headache With IntraNasal Ketamine: A Randomized Controlled Trial Evaluating the Efficacy of Intranasal Ketamine Versus Standard Therapy in the Management of Primary Headache Syndromes in the Emergency Department"
This is a randomized, single-blind, placebo controlled trial to evaluate the efficacy of sub-dissociative dose ketamine versus standard care therapy for acute headache management of in patients presenting to the emergency…
- Trial name
- THINK (NCT03081416)
- Testing
- Ketamine, Normal saline, Metoclopramide
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Infant Pain Management
White Noise and Buzzy for Reducing Pain During Infant Vaccination
This randomized controlled trial aims to evaluate the effectiveness of two non-pharmacological methods-white noise and the Buzzy device-in reducing pain experienced by infants during routine vaccination.
- Trial name
- NCT07286721
- Testing
- Standard Care (in control arm)
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
Pain, Post Operative Pain
Phase II Study of Inhaled AeroLEF for Analgesia After ACL Knee Surgery
To evaluate the safety and efficacy of self-titration to effective analgesia with inhaled AeroLEF in patients with moderate/severe acute pain in the post-surgical setting.
- Trial name
- Pain (NCT00791804)
- Testing
- AeroLEF
- Where
- 2 sites in Canada
- Volunteers
- 19 people
- Sponsor
- YM BioSciences
Femur Fracture
Compartment Psoas Block Efficacy and Safety
A randomized controlled trial to assess the efficacy and safety of the prolonged compartment psoas block for analgesia and anesthesia for femur surgery in the elderly
- Trial name
- NCT04648332
- Testing
- Bupivacaine Hydrochloride
- Where
- Ukraine
- Volunteers
- 90 people
- Sponsor
- Bogomolets National Medical University
Surgery, Obese
The Interest of the ANI in the Monitoring of Peroperative Analgesia in Bariatric Surgery
The intraoperative assessment of analgesia remains problematic and no analgesia monitor is used in routine practice.
- Trial name
- ANI (NCT03103698)
- Testing
- To demonstrate the monitoring of perioperative analgesia, Standard preoperative evaluation of analgesia
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Lumbar Disc Herniation
QLB vs mTLIP for Lumbar Spinal Surgery
Ultrasound-guided quadratus lumborum block (QLB) is a fascial plane block where local anesthetic is injected adjacent to the quadratus lumborum muscle with the goal of anesthetizing the thoracolumbar nerves.
- Trial name
- NCT05217121
- Testing
- Quadratus Lumborum Block, Modified-thoracolumbar interfascial plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Gastric Cancer
Effect of Pneumoperitoneum on Remifentanil Requirements in the Surgical Pleth Index-guided Analgesia
The primary purpose of this study is to investigate the effect of pneumoperitoneum on remifentanil requirements in the surgical pleth index-guided analgesia for laparoscopic gastrectomy.
- Trial name
- NCT03788447
- Testing
- High end-tidal CO2, Low CO2 group
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Ajou University School of Medicine
The Duration of Motor Block May Vary Between 12-36 Hrs
The Use of Bupivacaine and Ropivacaine for Sciatic Nerve Block
The duration of motor block for infragluteal parabiceps sciatic nerve block following total knee replacement may vary between 12-36 hrs depending on the amount of local anesthetic given.
- Trial name
- NCT01272921
- Testing
- Bupivacaine, Ropivacaine
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Northwestern University
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