Clinical trials: Pain Management and Care
Ventilator Lung; Newborn
NIPE as an Indicator of Pain in Sedated/Ventilated Patient Under 3 Years-old Hospitalized in Intensive Care Unit
The main objective is to assess correlation between Newborn Infant Parasympathetic Index values and external evaluation by Comfort Behaviour Scale during painful medical cares in sedated intubated children admitted in pediatric…
- Trial name
- NIPE (NCT04195672)
- Testing
- NIPE (MDoloris®) and CBS values
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Lille
Pain, Anxiety
Virtual Reality for Burn Wound Care Pain Control
The investigators propose to study the effects of virtual reality (VR) on patients' pain perception during burn wound care. Such variables include psychiatric diagnosis and standard pain coping (i.e. pain catastophizer vs.
- Trial name
- NCT00663013
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Weill Medical College of Cornell University
Patients With Acute Pain Admitted to the Intensive Care Unit
Epidural vs. Systemic Analgesia in the Intensive Care Unit
Many patients admitted to the general intensive care unit suffer from pain, whether acute or chronic. Those patients include post-operative patients, multi trauma, acute pancreatitis and patients with multiple rib fractures.
- Trial name
- NCT04996524
- Testing
- epidural analgesia
- Where
- Israel
- Volunteers
- 647 people
- Sponsor
- Meir Medical Center
Burns, Pain
Comparison of Monitored Anesthesia Care Using Remifentanil or Fentanyl for Major Dressing Changes in Burns
During their hospitalization, burn patients frequently require dressing changes that may be painful. Deep analgesia and sedation are used but carry the risk of remnant somnolence and other effects of anesthesia such as dizziness…
- Trial name
- NCT00326859
- Testing
- remifentanil
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Montreal Burn Centre
Critically Ill, Renal Replacement Therapy
Analgesia Nociception Index to Explore Autonomic Nervous System in Patients With Continuous Renal Replacement Therapy
The Analgesia Nociception Index (ANI) reflects the balance between sympathetic and parasympathetic tone. It is based on a specific interpretation of the R-R interval variation.
- Trial name
- UFANI (NCT06285162)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Chronic Pain, Complex Regional Pain Syndrome
Complex Regional Pain Syndrome: Analgesic Outcome
This retrospective observational study aims to describe the use and analyze the effectiveness of various analgesic interventions in patients diagnosed with Complex Regional Pain Syndrome (CRPS) at the Pain Management Center of…
- Trial name
- NCT07228949
- Where
- 2 sites in Canada
- Volunteers
- 201 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Pain, Chronic, Communication Research
Improving Communication About Pain and Opioids
The overall goal of this protocol is to pilot test a clinician training intervention that uses standardized patients (trained actors playing patient roles) as instructors who impart communication skills to primary care…
- Conditions
- Pain, Chronic, Communication Research, Opioid Use
- Trial name
- NCT03629197
- Testing
- Clinicians - Communication skills training, Clinician Control, Patient seeing trained clinician
- Where
- 2 sites in United States
- Volunteers
- 95 people
- Sponsor
- University of California, Davis
End-of-Life, Physical Suffering
Virtual Reality Therapy to Improve Physical and Psychological Symptoms and Quality of Life for End-of-life Patients on a Palliative Care Unit
People with advanced and life-threatening illnesses experience challenges across multiple domains of function including physical, psychological, social, and spiritual.
- Conditions
- End-of-Life, Physical Suffering, Psychological Distress
- Trial name
- NCT04966260
- Testing
- Standardized Virtual Reality, Control, Personalized Virtual Reality
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- Baycrest
Aortic Valve Replacement
Innovative Device for Pain Management by Millimeter Band Radiation: Electronic-Pain Killer
The objective of this study is to evaluate a new medical device in the management of pain. The principle of this new treatment is based on the emission of electromagnetic radiation in millimeter band.
- Trial name
- EPIKARD (NCT03889288)
- Testing
- Medical device - electronic-pain killer
- Where
- France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Grenoble
Chronic Pain, Opioid Use
Developing and Pilot Testing an Opioid Tapering Protocol
This study proposes to pilot test an intervention to facilitate opioid pain reliever (OPR) tapering in primary care. The intervention will incorporate a clinician embedded within primary care to follow tapering dose schedules to…
- Conditions
- Chronic Pain, Opioid Use, Analgesia
- Trial name
- TapPro (NCT04257695)
- Testing
- TapPro
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Albert Einstein College of Medicine
Colorectal Neoplasms
Safety and Efficacy Study of Intravenous Lidocaine After Colorectal Surgery: LIDOREHAB
The purpose of this study is to check if lidocaine intravenous administration during surgery and 24 hours after surgery, associated with standardised management of the patient, helps to accelerate recovery and to improve the…
- Trial name
- NCT00236249
- Testing
- Lidocaine
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Oral Mucositis
Ozone Therapy for Cancer Therapy-Related Oral Mucositis
This retrospective observational study will evaluate clinical data already available from adult cancer patients who developed cancer therapy-related oral mucositis during radiotherapy and/or chemotherapy and who were managed in…
- Trial name
- OMUC-O3 (NCT07638904)
- Testing
- Combined Ozone-Based Oral Care Protocol
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- University of Pavia
Single Level Lumbar Decompression and Fusion Spine Surgery
Multimodal Analgesia vs. Routine Care Pain Management for Lumbar Spine Fusion Surgery: A Prospective Randomized Study
The purpose of this study is to determine if post-operative pain and rate of recovery are improved in patients undergoing spine surgery using MMA (multimodal analgesia) compared to usual analgsic care.
- Trial name
- NCT02202369
- Testing
- Multimodal Analgesia Treatment, Standard of Care Pain Management Protocol
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Post ICU Syndrome, Chronic Pain
Early Care Program for the Management of Post-ICU Syndrome and Chronic Pain After COVID-19 Infection.
COVID-19 (coronavirus 2019) disease has led to a large number of hospital admissions, many of which require admission to intensive care (ICU).
- Conditions
- Post ICU Syndrome, Chronic Pain, Covid-19
- Trial name
- PAIN-COVID (NCT04394169)
- Testing
- Intervention program
- Where
- Spain
- Volunteers
- 102 people
- Sponsor
- Hospital Clinic of Barcelona
Endometriosis, Chronic Pain
Virtual Mindfulness for the Management of Endometriosis Pelvic Pain.
Endometriosis is a gynecologic condition that can cause severe pelvic pain and significantly impair quality of life. Endometriosis symptoms cannot always be controlled by medical therapy or surgery alone, indicating a need for…
- Trial name
- NCT05554497
- Testing
- Mindfulness-based stress reduction curriculum
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Acute Pain
Virtual Reality Use for Peri-Procedural Analgesia and Anxiolysis
Currently, most analgesic regimens for painful bedside procedures rely on pharmacologic sedation or high doses of opioids (e.g.: nurse-administered IV opioids, anxiolytics, and sedatives; patient-controlled analgesia…
- Trial name
- NCT04218396
- Testing
- Virtual Reality use during painful bedside procedure, Standard Treatment during painful bedside procedure
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Pain, Chronic, Cancer Pain
Telemedicine Versus In-Person Follow-up for Cancer Pain Management: An Equity and Cost Analysis Comparison Using a Prospective Quasi-Experimental Design
Cancer is the second leading cause of death worldwide, with approximately 18.1 million new cases and 9.6 million deaths reported in 2018.
- Conditions
- Pain, Chronic, Cancer Pain, Cancer Related Pain
- Trial name
- NCT05628246
- Testing
- Telemedicine, In-person
- Where
- Thailand
- Volunteers
- 193 people
- Sponsor
- Mahidol University
Arthroscopic Shoulder Surgery
Erector Spinae Block Versus Shoulder Periarticular Anesthetic Infiltration for Arthroscopic Shoulder Surgery
Arthroscopic shoulder surgery is a common and minimally invasive procedure utilized for different shoulder pathologies, but it is often associated with moderate to severe postoperative pain that may interfere with patients'…
- Trial name
- NCT03691922
- Testing
- Erector Spinae Plane (ESP) Block, Periarticular Infiltration (PAI)
- Where
- Canada
- Volunteers
- 62 people
- Sponsor
- McMaster University
Chronic Pain
Observational Trial of Qigong for Patients in Pain
This observational study documented outcomes resulting from qigong practice as a complementary self-care practice. All subjects continued with their usual medical care.
- Trial name
- NCT04279639
- Testing
- qigong
- Volunteers
- 35 people
- Sponsor
- Nova Scotia Health Authority
Burns, Pain
Virtual Reality in Burn Pain Management
To examine the safety and efficacy of Virtual Reality (VR) distraction therapy in burn patients experiencing severe procedural pain during wound care.
- Trial name
- NCT00593086
- Testing
- Pain management, Standard of care/no virtual reality game
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- United States Army Institute of Surgical Research