Clinical trials: Pain Management and Care
Pain
Pain Management of Intensive Care Unit Patients
The purpose of this study is to evaluate the effect of an algorithm, where ICU patients pain are assessed systematically with valid pain assessment tools and where pain is treated after pain intensity score.
- Trial name
- NCT01599663
- Testing
- Pain management algorithm
- Where
- Norway
- Volunteers
- 650 people
- Sponsor
- Ostfold Hospital Trust
Pain, Pain Management
Effective Screening for Pain Study
In light of the importance of pain and widespread interest in patient-centeredness, the Department of Veterans Affairs (VA) has been emphasizing and successfully making pain and its management a routine feature of the health…
- Trial name
- ESP (NCT01816763)
- Testing
- NRS pain one week, PEG, DVPRS
- Where
- 3 sites in United States
- Volunteers
- 569 people
- Sponsor
- VA Office of Research and Development
Chronic Pain
Computerized Decision Support Tool for Pain Management in Primary Care
Chronic pain is highly prevalent, compromises quality of life, and increases care utilization. Primary care providers are challenged to provide effective treatments, use opioid therapy appropriately, and address the adverse…
- Trial name
- NCT04716621
- Testing
- Early intervention, Delayed intervention
- Volunteers
- 528 people
- Sponsor
- MJHS Institute for Innovation in Palliative Care
Malignant Bowel Obstruction, Cancer Pain
Lidocaine Infusions for Pain in Patients With Malignant Bowel Obstruction
Malignant bowel obstruction is a frequent complication of advanced cancer, particularly of abdominal and pelvic origin, and most affected patients experience pain.
- Conditions
- Malignant Bowel Obstruction, Cancer Pain, Intestinal Obstruction
- Trial name
- NCT07856251
- Testing
- Lidocaine
- Volunteers
- 50 people
- Sponsor
- Fundación Santa Fe de Bogota
Burns, Pain
Comparison of Monitored Anesthesia Care Using Remifentanil or Fentanyl for Major Dressing Changes in Burns
During their hospitalization, burn patients frequently require dressing changes that may be painful. Deep analgesia and sedation are used but carry the risk of remnant somnolence and other effects of anesthesia such as dizziness…
- Trial name
- NCT00326859
- Testing
- remifentanil
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Montreal Burn Centre
Lumbar Spine Fusion, Pain
Epidural Analgesia Versus IV Analgesia in Lumbar Spine Fusions
1. Protocol Title - A Comparison of Epidural Analgesia with Standard Care Following Lumbar Spinal Fusion: A Prospective Randomized Study 2.
- Conditions
- Lumbar Spine Fusion, Pain, Back Pain
- Trial name
- NCT01986946
- Testing
- Epidural Catheter - Dilaudid, Dilaudid
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Duke University
Critically Ill, Renal Replacement Therapy
Analgesia Nociception Index to Explore Autonomic Nervous System in Patients With Continuous Renal Replacement Therapy
The Analgesia Nociception Index (ANI) reflects the balance between sympathetic and parasympathetic tone. It is based on a specific interpretation of the R-R interval variation.
- Trial name
- UFANI (NCT06285162)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Quality of Life
Acupuncture and Integrative Care in Gynecological Surgery
Patients undergoing surgical procedures for gynecological cancer are frequently challenged by intense anxiety prior to surgery, reflecting the accompanying uncertainty regarding the diagnosis, treatment and prognosis of their…
- Trial name
- NCT03560388
- Testing
- Acupuncture and touch/relaxation
- Where
- Israel
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Breast Cancer, Postoperative Recovery
ERAS Protocols in Breast Conserving Surgery
Enhanced Recovery After Surgery (ERAS) protocols have been of increasing interest in the surgical community for decades. The emphasis has been development of protocols to maximize pain control post-operatively without the use of…
- Trial name
- ERAS (NCT06938581)
- Testing
- ERAS Protocol, Standard Perioperative Care
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- University of Nebraska
Pelvic Pain, Distress, Emotional
Pelvic Pain Education and Skills Training for Women Veterans
The goals of this pilot randomized clinical trial are three-fold: 1) to test the feasibility of conducting a larger randomized trial using a brief Acceptance and Commitment Training (ACT) group intervention for women veterans…
- Trial name
- NCT06062043
- Testing
- Brief ACT with CPP Education Treatment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Baylor College of Medicine
Dysmenorrhea
Dysmenorrhea Exploration in Teenagers, Their Parents and Caregivers
Teenagers experimenting severe dysmenorrhea also face age-specific challenges, particularly impacting their self-confidence, self-esteem, and relations.
- Trial name
- DEMETER (NCT05414825)
- Testing
- focus group interview
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Osteoarthritis, Knee
Efficacy of UniRelieverTM Offloading Brace in the Management of Knee Osteoarthritis
The objective of this study is to assess the efficacy and performance of a new semi-rigid offloading brace in the management of knee osteoarthritis.
- Trial name
- UNIBRACE (NCT05905809)
- Testing
- UniRelieverTM offloading brace (THUASNE), Unloader One® X brace (Össur)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Thuasne
Low Back Pain, Pain
Care Management for the Effective Use of Opioids
The CAre Management for the Effective use of Opioids (CAMEO) trial is a 2-arm randomized clinical trial to compare the effectiveness of pharmacological vs. behavioral approaches for chronic lower back pain.
- Trial name
- CAMEO (NCT01236521)
- Testing
- Pharmacological (MED), Behavioral treatment (CBT)
- Where
- United States
- Volunteers
- 261 people
- Sponsor
- VA Office of Research and Development
Abdominal Surgery, Respiratory Failure
Metabolites of Tramadol in the Postoperative Surgical Patients
Tramadol is opioid analgesic widely used to treat moderate to severe pain. It is metabolized by cytochrome CYP2D6 into two major metabolites: pharmacologically active metabolite O-desmethyltramadol (M1) and inactive…
- Conditions
- Abdominal Surgery, Respiratory Failure, Renal Failure, Liver Dysfunction
- Trial name
- METRAS (NCT04004481)
- Testing
- Postoperative analgesia using tramadol
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- Osijek University Hospital
Chronic Pain
Chronic Pain Management In Primary Care Using Behavioral Health Consultants
The purpose of this randomized pragmatic trial is to assess the effect of monthly booster contacts on long-term Brief Cognitive Behavioral Therapy for Chronic Pain (BCBT-CP) pain outcomes compared to BCBT-CP without a booster in…
- Trial name
- NCT04680000
- Testing
- Brief Cognitive Behavioral Therapy for Chronic Pain (BCBT-CP), BCBT-CP Booster
- Where
- 3 sites in United States
- Volunteers
- 716 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Surgery, Pain
Evaluation of the Interest of the Instillation of Saline Intraperitoneally (INSI ) Versus Instillation of Naropin the Surgical Site Versus Lung Recruitment Maneuvers ( PVM ) in the Management of Pain After Laparoscopic Cholecystectomy in Ambulatory Care
Known to reduce analgesics and length of hospitalization in conventional surgery, laparoscopy is characterized by frequent post-operative pain and can decrease the patient's quality of immediate postoperative life and sometimes…
- Trial name
- VSD (NCT02819544)
- Testing
- Sodium chloride administration, Ropivacaine administration
- Where
- 2 sites in France
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Pain
Influence of Physostigmine on Patient-Controlled Analgesia (PCA) in Postoperative Intensive Care Patients
The study is to evaluate the influence of physostigmine in the postoperative period in intensive care patients considering pain quality, opioid consumption, hemodynamics and mobilisation.
- Trial name
- ANA06103 (NCT00608621)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Klinikum Ludwigshafen
Sickle Cell Disease
Osteopathic Manipulation in the Management of Pain Associated With Sickel Cell Disease
Background: Sickle cell disease is the most common monogenic disease in the world caused by a mutation in the β-globin gene which creates abnormal hemoglobin called HbS.
- Trial name
- OSTEODREP (NCT05632289)
- Testing
- osteopathic manipulative therapy
- Where
- France
- Volunteers
- 37 people
- Sponsor
- College Osteopathique de Provence Aix-Marseille
Chronic Pain, Acute Pain
Lexington Observational Study of Treatment With Compounded Pain Creams
A two-year + 3 Mo. observational study to track compliance and outcomes in adult patients prescribed compounded pharmaceutical creams for the treatment of pain.
- Trial name
- TrackingCPC (NCT02195752)
- Testing
- Compounded Pain Cream
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Lexington Independent Studies, LLC
Craniotomy, Neurosurgical Patients
an Analgesia-first Strategy Without Hypnotic Sedatives in Adult Patients Admitted to the Intensive Care Unit After Neurosurgical Craniotomy
Analgesia and sedation are core components of intensive care unit (ICU) care. They are used to relieve pain and anxiety, prevent harmful physiological stress responses, improve tolerance of invasive devices and mechanical…
- Trial name
- NCT06727435
- Testing
- analgesia-first strategy without hypnotic sedatives
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Beijing Tiantan Hospital