Clinical trials: Pain Management and Care
Trismus, Edema
Management of Postoperative Complications After Mandibular Third Molar Extraction Using Submucosal Triamcinolone Injection, Kinesiology Taping, and Standard Care
The surgical removal of impacted lower wisdom teeth (mandibular third molars) frequently leads to uncomfortable postoperative symptoms, including pain, facial swelling (edema), and restricted jaw movement (trismus).
- Conditions
- Trismus, Edema, Pain
- Trial name
- NCT07719270
- Testing
- Triamcinolone Acetonide 10mg, Kinesiology Taping, Standard Postoperative Care
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Allama Iqbal Medical College
Intensive Care Unit Patients, Pain Management
Effects of Voice Records on Patient Outcomes Surgical Intensive Care Unit
This randomized kontrolled study is aimed to contribute to the literature on recognising, evaluating and reducing stress in the intensive care unit, which is one of the main responsibilities of surgical nurses, and to increase…
- Conditions
- Intensive Care Unit Patients, Pain Management, Stress Response
- Trial name
- NCT07007754
- Testing
- Voice recording playback
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Aydin Adnan Menderes University
Pain
Study of Medication Compliance - a Comparison of Patients in Pain Management and Pre-surgical Patients
In this study medication compliance regarding current drug use is investigated using toxicological analyzes in two patient groups: patients from a pain management department and pre-surgical control patients.
- Trial name
- NCT01625065
- Where
- Germany
- Volunteers
- 343 people
- Sponsor
- Ruhr University of Bochum
Acute Low Back Pain, Musculoskeletal Pain
Physiotherapy in Emergency Department for Acute Lumbar Spasm
This retrospective observational study aims to evaluate the effectiveness of physiotherapy interventions-such as manual therapy, electrotherapy (TENS), and individualized exercise programs-in managing acute lumbar spasm in…
- Conditions
- Acute Low Back Pain, Musculoskeletal Pain, Emergency Care
- Trial name
- PT-ED (NCT06987656)
- Testing
- Standard Pharmacologic Treatment, Physiotherapy Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Duzce University
Analgesia
Efficacy and Safety of Remifentanil for Mechanically Ventilated Patients in Intensive Care Unit
Remifentanil has been approved by the FDA for continuation as an analgesic into the immediate postoperative period in adult patients under the direct supervision of an anesthesia practitioner in a postoperative anesthesia care…
- Trial name
- NCT05641909
- Testing
- Remifentanil, Fentanyl
- Where
- 18 sites in China
- Volunteers
- 138 people
- Sponsor
- Southeast University, China
HIV Infection, Pain
Targeting Effective Analgesia in Clinics for HIV - Intervention
The TEACH randomized controlled trial will test the effectiveness of a collaborative care intervention directed towards physicians who provide care for HIV-infected persons to improve the quality of care for prescribing chronic…
- Conditions
- HIV Infection, Pain, Drug Dependence
- Trial name
- TEACH (NCT02564341)
- Testing
- Collaboration with an IT enabled nurse care manager, Education and academic detailing, Facilitated access to a specialist in addictions
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Boston Medical Center
Analgesia, Ketamine Toxicity
Efficacy and Safety of Continuous Infusion of Ketamine in Pediatric Intensive Care Unit (KISS Study)
This study, prospectively evaluate the efficacy and safety of ketamine administered in continuous infusion lasted more than 12 hours in children admitted to Pediatric Intensive Care Unit of Padova.
- Conditions
- Analgesia, Ketamine Toxicity, Bronchospasm, Sedation Complication
- Trial name
- KISS (NCT04427605)
- Where
- Italy
- Volunteers
- 57 people
- Sponsor
- Azienda Ospedaliera di Padova
Labor Pain
Intermittent Automated Devices for Labor Analgesia in Emilia Romagna
The study aims to determine whether the use of automated intermittent devices for labor analgesia could prevent the increase of instrumental deliveries, with same analgesia.
- Trial name
- PA-RER (NCT02710877)
- Testing
- Programmed Intermittent bolus, Manual epidural bolus, Levobupivacaine
- Where
- 3 sites in Italy
- Volunteers
- 671 people
- Sponsor
- University of Modena and Reggio Emilia
Chronic Pain
Group-based Integrative Pain Management (IPMP+ Pilot)
Socioeconomically disadvantaged populations have a high prevalence of chronic pain, exacerbated by social isolation, intersectional stigma, and disparities in pain assessment and treatment options.
- Trial name
- NCT05906784
- Testing
- group acupuncture, Integrative Group Medical Visits
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of California, San Francisco
Pain, Pain Management
Individualized Analgesia in the Intensive Care Unit With a New Pain Assessment Bundle and Protocolized Analgesia Adjustments
Both severe pain and opioid therapy are associated with negative effects. The experience of pain is common in the intensive care unit, but it is highly individual and difficult to assess, as patients are often unable to…
- Conditions
- Pain, Pain Management, Critical Illness
- Trial name
- INVISIBLE (NCT07473115)
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University of Zurich
Pain Management, Traditional Chinese Medicine
Bringing Acute and Wellness Care to Underserved Populations Using Traditional Chinese Medicine
At a time when there is so much focus in the United States on reducing the cost of health care delivery while maximizing the effectiveness of health care performance, Traditional Chinese Medicine (acupuncture, herbal treatment…
- Trial name
- NCT01059487
- Testing
- Traditional Chinese Medicine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Chicago College of Oriental Medicine
Critical Illness, Post Intensive Care Unit Syndrome
pEEG Monitoring Effect on Delirium, Ventilator Days, and PICS
The goal of this multi-site observational study is to compare delirium rates, days on mechanical ventilation, and Post Intensive Care Syndrome (PICS) rates in adult Intensive Care Unit (ICU) patients.
- Conditions
- Critical Illness, Post Intensive Care Unit Syndrome, Post Intensive Care Syndrome, Mechanical Ventilation Complication
- Trial name
- NCT06019078
- Testing
- SedLine
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Fraser Health
Back Pain, Low Back Pain
Standardizing Management of Patients With Low Back Pain in Primary Care and Physical Therapy
The purpose of this study is to compare the clinical outcomes and costs associated with two different management strategies for patients with acute low back pain who consult their primary care physician.
- Trial name
- NCT00769626
- Testing
- Usual Care, Early Treatment
- Where
- 3 sites in United States
- Volunteers
- 15 people
- Sponsor
- Intermountain Health Care, Inc.
Cancer, Pain
Improving Cancer Pain Management Through Self-Care
This study will test two different doses of a psychoeducational intervention to improve cancer pain management. In addition, the study will determine if the changes in pain management behaviors that the patients and family…
- Trial name
- NCT00708019
- Testing
- PRO-SELF PLUS Pain Management Program
- Where
- 2 sites in United States
- Volunteers
- 185 people
- Sponsor
- University of California, San Francisco
General Surgery
Inflammation and Postoperative Tramadol Analgesia
Patients will be admitted in the intensive care unit after major abdominal surgery. All patients will receive 100 mg of tramadol intravenously every 6 hours.
- Trial name
- NCT04330157
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- Osijek University Hospital
Pain, Scars
Survey Study for Pain Management, Wound Care, Scar Care or UDT
This is a survey study that will be given to patients who have been prescribed a topical compound for pain management, wound care or scar care or to patients who have been requested to do a urinary drug test (UDT) by their…
- Conditions
- Pain, Scars, Wounds, Urinary Drug Testing
- Trial name
- NCT02195063
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Rahm Foundation
Pain
Vibration and Shotblocker Use in Pregnant Women While Giving Tetanus + Diphtheria Vaccine
Tetanus-diphtheria vaccine administered to pregnant women may cause pain during and after administration. Due to the pain that may occur, the compliance of pregnant women towards the vaccine may be impaired.
- Trial name
- NCT05701904
- Testing
- Local mechanical vibration, Shotblocker group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Palliative Care, Pain Management
Medical Hypnosis and Music for Palliative Care
The goal of this randomized controlled trial is to evaluate the efficacy of a personalized multimodal intervention program (MuzHyp) including hypnosis, music or their combination to improve palliative care at home.
- Conditions
- Palliative Care, Pain Management, Anxiety, Well-being
- Trial name
- MuzhypforPC (NCT05951257)
- Testing
- Personalized multimodal intervention involving hypnosis and/or music
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Laval University
Oral Mucositis, Oral Stomatitis
Ozone Therapy for Oral Mucositis in Patients Receiving Head and Neck Cancer Radio- and Chemotherapy
Oral mucositis is a frequent and painful side effect of radio- and chemotherapy, especially in patients with head and neck cancer.
- Conditions
- Oral Mucositis, Oral Stomatitis, Head and Neck Cancer Squamous Cell Carcinoma, Radiotherapy Induced Mucositis
- Trial name
- OZOMUC (NCT07199712)
- Testing
- Ozone Therapy (In-Office and Home-Based Treatment)
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- University of Pavia
Abdominal Surgery, Postoperative Recovery
Effect of AI-Personalized Virtual Reality on Postoperative Recovery After Major Abdominal Surgery
Major abdominal surgery is frequently associated with postoperative pain, anxiety, delayed recovery, and prolonged hospitalization.
- Conditions
- Abdominal Surgery, Postoperative Recovery, Postoperative Pain, Length of Hospital Stay
- Trial name
- VR-RECOVER (NCT07493499)
- Testing
- Immersive Virtual Reality (VR), Standard Perioperative Care and Enhanced Recovery Protocol
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Alexandria University