Clinical trials: Pain Management and Care
Primary Immunodeficiency Diseases (PID)
Virtual Reality on Pain and Fear Levels of Children With Primary Immunodeficiency
In this study, it is aimed to investigate the effect of virtual reality and tablet video viewing intervention on pain and fear levels and vital signs of children during peripheral venous catheter placement for intravenous…
- Trial name
- NCT07004803
- Testing
- Virtual reality video watching, Tablet video watching
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Dr. Hatice Dönmez
Migraine
ZAP, US. Zomig for Appropriate for Primary Care
The purpose of this study is to determine how useful and effective the use of ZOMIG-ZMT™ (zolmitriptan) 5.0 mg and ZOMIG® Nasal Spray (zolmitriptan) 5.0 mg is for patients, in treating migraine over a period of 6 months
- Trial name
- NCT00637286
- Testing
- Zolmitriptan
- Volunteers
- 120 people
- Sponsor
- AstraZeneca
Constipation, Abdominal Pain
Effect of Abdominal Massage on Palliative Care Patients
Constipation is defined as infrequent defecation or difficulty in evacuation. Although the constipation problem is mostly self-managed by the patients, 22% mostly refer to primary health care providers (>50%), resulting in large…
- Conditions
- Constipation, Abdominal Pain, Palliative Care
- Trial name
- NCT05580679
- Testing
- Abdominal massage
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bartın Unıversity
Cancer Pain, Opioid Use
Epidural Association of Morphine and Ropivacaine for Cancer Pain Treatment
In 2012, more than 14 million cases of cancer were diagnosed worldwide, with the forecast for 2025 exceeding 20 million. Pain is the most critical symptom that accompanies cancer.
- Conditions
- Cancer Pain, Opioid Use, Cost Analysis, Palliative Care
- Trial name
- NCT05558397
- Testing
- Interventional Group (Epidural morphine), Control Group (Oral morphine)
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Federal de Alfenas
Pain
Self-management Support in Cancer Pain
Pain is a prevalent and distressing symptom in patients with cancer, having an enormous impact on functioning and quality of life.
- Trial name
- NCT02333968
- Testing
- Self-management support
- Where
- 2 sites in Netherlands
- Volunteers
- 174 people
- Sponsor
- Maastricht University Medical Center
Postoperative Pain
Efficacy of EXPAREL in Comparison to Standard of Care for the Treatment of Post Operative Dental Implant Pain
This study is researching managing postsurgical pain by injecting both short-acting local anesthetics and EXPAREL® at the time of surgery and reviewing if it could reduce or eliminate the need for postsurgical opioids and improve…
- Trial name
- FAST (NCT02533440)
- Testing
- EXPAREL and Local Anesthetics, Oral Opioid and Local Anesthetics
- Where
- 3 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Bellaire Facial Surgery Center
Labor Pain, Virtual Reality
Virtual Reality, Experience During Labour; a Qualitative Research (VIREL)
Childbirth is associated with labour pain and can be regarded as one of the most serious kinds of pain. Labour pain management methods include pharmacological and non-pharmacological methods.
- Conditions
- Labor Pain, Virtual Reality, Analgesia, Pain
- Trial name
- VIREL (NCT04858984)
- Testing
- Virtual Reality
- Where
- Netherlands
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Upper Abdominal Malignancies, Upper Gastrointestinal Cancer
Comparison of CT-Guided Celiac Plexus Neurolysis and Pharmacotherapy
After enrolment, patients were randomly assigned to two groups by means of a lottery procedure, whereby each patient blindly chose one of two labelled slips, resulting in group assignment to receive.
- Trial name
- NCT07761650
- Testing
- CT-guided celiac plexus neurolysis, Standard pharmacotherapy
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Mayo Hospital Lahore
Neurological Impairment
Music Therapy for Pain Modification in Pediatric Palliative Care
The purpose of this within-subjects randomized controlled trial is to determine whether two music therapy interventions are efficacious in reducing pain symptoms, in order to improve the quality of care for children in pediatric…
- Trial name
- NCT01456884
- Testing
- Live guitar and vocal music therapy, Vibroacoustic Music Therapy
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- University of British Columbia
Pediatric Oncology
The Effects of Nonpharmacological Methods Used in Subcutaneous Application on Pain, Anxiety, and Fear Levels in Children
Childhood cancers are increasing globally and require long-term invasive treatments, particularly subcutaneous applications that often cause pain, swelling, and anxiety.
- Trial name
- NCT07163104
- Testing
- Kaleidoscope, Buzzy, Cognitive behavioral intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Zubeyde Ezgi Ercelik
Sedative Adverse Reaction, Analgesic Adverse Reaction
The Use of Midazolam and Remifentanil During Dialysis Access Procedures
BACKGROUND: Sedation and analgesia are related to unexpected adverse events in chronic renal failure patients undergoing arteriovenous fistula placement procedures under monitored anesthesia care (MAC).
- Conditions
- Sedative Adverse Reaction, Analgesic Adverse Reaction, Midazolam Adverse Reaction, Adverse Reaction to Drug
- Trial name
- NCT04226443
- Testing
- Midazolam intravenous injection, Remifentanil intravenous bolus dose
- Volunteers
- 99 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Acute Pain
Benzodiazepines for the Reduction of Distress and Pain During and After Emergency Department Care
In this proposal, the investigators will determine if a single dose of oral lorazepam reduces distress, pain severity, and need for opiate analgesics both in the ED and in the acute recovery period after discharge.
- Trial name
- NCT03756038
- Testing
- Lorazepam
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Maria Pacella
Chronic Pain
Adapting and Implementing a Nurse Care Management Model to Care for Rural Patients With Chronic Pain
Chronic pain affects over 20% U.S. adults and has debilitating effects on quality of life and physical and mental health. Individuals living in rural communities experience higher rates of chronic pain as well as poorer health…
- Trial name
- AIM-CP (NCT06407115)
- Testing
- Cognitive Behavioral Therapy (CBT), Exercise Counseling and tele-EnhanceFitness, Care Coordination
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- University of Washington
Critical Illness
the Research of Analgesia and Sedation Effect of Remifentanil on ICU Short Operation
Remifentanil is one kind of opiates with strong analgesic effect,which has the rapid onset and short lasting duration. Remifentanil usually is used to help reducing the pain of patients with mechanical ventilation in ICU.
- Trial name
- NCT02635802
- Testing
- Remifentanil, Lidocaine, Remifentanil+Lidocaine
- Volunteers
- 1,500 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Postoperative Pain, Satisfaction with Care
Thoracic Spinal Versus Thoracic Epidural Anesthesia for Patients with Chronic Obstructive Pulmonary Disease Undergoing Supine Percutaneous Nephrolithotomy for Management of Renal Stones.
Owing to the elevated risk of perioperative comorbidities, chronic obstructive and restrictive pulmonary disorders can be a challenging task for the anesthetist.
- Trial name
- NCT06663488
- Testing
- Thoracic epidural anesthesia, Thoracic spinal anesthesia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Temporomandibular Disorders
CONDOR Temporomandibular Muscle and Joint Disorders (TMJD) Survey
The purpose of study was to characterize using an online questionnaire the feasibility of recruiting dentists in primary care dental practices in the practice-based research network and documenting their current initial care for…
- Trial name
- NCT01201512
- Where
- United States
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network
Depression, Pain
Improving Care of Patients With Heart Failure
Heart failure (HF) affects more than 5 million Americans and is a major source of morbidity and mortality. Despite optimal management, over half of patients with HF suffer from pain, dyspnea, fatigue, and depression that diminish…
- Conditions
- Depression, Pain, Dyspnea, Quality of Life
- Trial name
- NCT01461681
- Testing
- Symptom Management Service for Heart failure
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Analgesia
Pharmacoeconomic Consequences Of Analgesia in the Intensive Care Unit (ICU)
This study will be a multicentre randomized, open-label, phase IIIb study. This study will evaluate two different techniques of sedation: an analgesia based regimen with remifentanil versus a conventional sedation based regimen…
- Trial name
- NCT00436345
- Testing
- Remifentanil, Propofol
- Where
- 6 sites in Italy
- Volunteers
- 39 people
- Sponsor
- GlaxoSmithKline
Intensive Care Patients, Pain
The Effect of Acupressure Applied to Icu on Pain and Physiological Parameters
The aim of this experimental study is to determine the effect of acupressure applied to intensive care patients on pain and physiological parameters (blood pressure, heart rate, respiration and oxygen saturation).
- Trial name
- EFFECTOFACU (NCT06271226)
- Testing
- acupressure, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ondokuz Mayıs University
Fascial Plane Block, ICU Length of Stay
Postoperative Analgesia and Ventilation After Cardiac Surgery
Cardiac surgery performed via median sternotomy is associated with significant postoperative pain due to extensive tissue trauma, sternal bone healing, and mediastinal retraction.
- Conditions
- Fascial Plane Block, ICU Length of Stay, Mechanical Ventilation Duration, Oxygenation
- Trial name
- NCT07475884
- Testing
- conventional analgesic regimen, Fascial Plane Blocks
- Where
- Turkey (Türkiye)
- Volunteers
- 206 people
- Sponsor
- Bursa City Hospital