Clinical trials: Pain Management and Care
Myalgia of Mastication Muscle
Behavioral Therapy and Self-care vs Thermoformed Occlusal Splints in the Treatment of Masticatory Muscles Pain
The objective of this study was to compare the clinical effectiveness of personalized thermoformed occlusal splints together with behavioral and self-care therapy in the management of myalgia of the masticatory muscles.
- Trial name
- NCT04588636
- Testing
- behavioral and self-care therapy, rigid occlusal splint (ROS), soft occlusal splint (SOS)
- Where
- Chile
- Volunteers
- 46 people
- Sponsor
- Universidad Nacional Andres Bello
Osteoarthritis, Knee
Efficacy of UniRelieverTM Offloading Brace in the Management of Knee Osteoarthritis
The objective of this study is to assess the efficacy and performance of a new semi-rigid offloading brace in the management of knee osteoarthritis.
- Trial name
- UNIBRACE (NCT05905809)
- Testing
- UniRelieverTM offloading brace (THUASNE), Unloader One® X brace (Össur)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Thuasne
Pain, Postoperative, Opioid Use Disorder
Patient Engagement in Perioperative Pain Management Project
Previously, the study team evaluated the implementation and effectiveness of the Johns Hopkins Perioperative Pain Program (PPP), which coordinates continuum of care for surgical patients on chronic opioid therapy throughout the…
- Trial name
- NCT05252767
- Testing
- Patient Engagement Tools, Educational Guide
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Johns Hopkins University
Chest Pain
A Care Management Intervention for Non-cardiac Chest Pain
The investigators developed and implemented an eight-week multicomponent care management intervention for non-cardiac chest pain. Team members including a cardiologist, nurse, and psychiatrist.
- Trial name
- NCCP (NCT04904198)
- Testing
- Care Management Intervention for non-cardiac chest pain
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Uterine Evacuation
The Impact of Doulas in Early Pregnancy Management
The purpose of the study is to examine the impact of doula support for women undergoing a manual vacuum aspiration (MVA) for an early pregnancy failure or undesired pregnancy.
- Trial name
- NCT02165540
- Testing
- Doula
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Surgery
Effectiveness of Animation-Based Education Given to Elderly Patients Undergoing Coronary Artery Bypass Graft Surgery
It was conducted to measure the effectiveness of animation-based training given to elderly patients who will undergo coronary artery bypass graft surgery on the patients' pain, fear, anxiety and self-care management.
- Trial name
- NCT06928025
- Testing
- Preoperative Education
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ayşegül Sena Pirgaip Yavuz
Laceration of Skin
IN Ketamine vs IN Midazolam and Fentanyl for Laceration Repair
Often, repair of the cuts (laceration repair) proves to be traumatic for the children and the parents. Nasal spray (Intranasal/IN) approaches for procedural pain reduction, such as during dental work, have been demonstrated to…
- Trial name
- NCT03528512
- Testing
- Ketamine, Midazolam and fentanyl
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Corewell Health East
Anxiety, Pain
Effect of Augmented Reality on Dental Anxiety and Pain Perception in Children
The aim of this study is to reduce dental anxiety in children by using augmented reality (AG) with a special content and innovative interactive methods, to determine the level of stress experienced by patients during dental…
- Trial name
- NCT06530654
- Testing
- Distraction by dentist, Distraction by cartoon movie, AG-active distraction group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Pain
Description of the Use of Subcutaneous Acetaminophen in Palliative Care Unit in France: Descriptive Questionnaire Survey
Acetaminophen is a drug commonly used in palliative care unit, for its antalgic and antipyretic effects. Several administration routes are possible but the use of the sub-cutaneous route is actually not supported by…
- Trial name
- EnPasc (NCT03349853)
- Volunteers
- 131 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Chronic Pain
Comprehensive Opioid Management in Patient Aligned Care Teams
This study will enroll Veterans with chronic pain who have been receiving opioid medications (like methadone, percocet, oxycontin) on a regular basis for at least 3 months to treat their pain.
- Trial name
- COMPACT (NCT01737073)
- Testing
- IVR self-management, Opioid monitoring, Enhanced usual care
- Where
- 2 sites in United States
- Sponsor
- VA Office of Research and Development
Pain Management, Wound Care
The Application of Virtual Reality Goggles During the First Wound Dressing After Open Heart Surgery
The aim of this study is to examine the effect of virtual reality glasses, a non-pharmacological method used in pain and anxiety management in nursing practices, on the pain, anxiety, and vital parameters perceived by patients…
- Conditions
- Pain Management, Wound Care, Heart Surgery, Heart Surgery Via Sternotomy
- Trial name
- NCT07068594
- Testing
- Virtual Reality Goggles
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Aydin Adnan Menderes University
Pregnancy, Labor Pain
Storytelling for Provider Empathy & Patient Trust in Obstetric Care
Aim 3 is a provider-focused pilot randomized controlled trial evaluating a digital storytelling intervention to increase obstetric care providers' empathy and to examine associations with postpartum patient trust.
- Trial name
- NCT07588308
- Testing
- Digital storytelling video + written reflection, General culturally sensitive care materials
- Volunteers
- 120 people
- Sponsor
- Duke University
Non Pharmacological Pain Management
Effect of Facilitated Tucking and Gentle Human Touch on Procedural Pain Among Neonates
This is a Randomized Control Trial intended to investigate the effect of two non-pharmacological interventions on procedural pain among neonates.
- Trial name
- NCT06415240
- Testing
- Facilitated Tucking, Gentle Human Touch
- Where
- 2 sites in Pakistan
- Volunteers
- 159 people
- Sponsor
- Shifa Tameer-e-Millat University
Dental Pain, Dental Anxiety
Evaluation of the Sedative Effect of Contextualized Music Listening on Patient Pain and Anxiety in a Dental Care Setting
The goal of this clinical study is to determine whether listening to culturally and personally contextualized music can reduce pain and anxiety in adults undergoing dental procedures.
- Trial name
- NCT07543042
- Testing
- Baseline Assessment (T0), Control Condition - Silence (Pre-Music Phase), Music Listening Condition (Intervention Phase)
- Where
- Lebanon
- Volunteers
- 30 people
- Sponsor
- Rawane El Dimachki
Severe, Acute Pain in a Pre-hospital Setting
Pre-hospital Morphine Titration : Comparison of 0,05 Versus 0,1 mg/kg
Efficacy and safety of morphine titration on acute pain in emergency medical mobile units with initial bolus of 0.1 mg/kg plus 0.05 mg/kg versus morphine titration with initial bolus of 0.05 mg/kg plus 0.025 mg/kg
- Trial name
- NCT00237731
- Testing
- morphine
- Where
- France
- Volunteers
- 106 people
- Sponsor
- University Hospital, Toulouse
Burn
VRH Pain Reduction During Burn Wound Care and Physical Therapy
Using Virtual Reality Hypnosis to relief pain and anxiety for burn patients.
- Trial name
- VRH (NCT00260221)
- Testing
- using VR hypnosis/distraction and audio hypnosis
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Pain, Post-operative Pain Control
Effect of Lidocaine in Reducing Opioids Requirement in Day Care Surgery
1. *Reduced opioid consumption 2. *Decreased pain scores 3. *Fewer opioid-related side effects 4. *Improved patient satisfaction
- Conditions
- Pain, Post-operative Pain Control, Post-operative Pain
- Trial name
- NCT06717672
- Testing
- Lidocaine 2% without vessel constrictor, Normal Saline
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Liaquat National Hospital & Medical College
Post-operative Pain, Acute, Opioid Use, Unspecified
Patient Centered Post-Op Pain Management Software Tool Interventional Study Verses Standard of Care
The goal of this clinical trial is to learn if the Pain Coach App will result in less opioids being prescribed to and used by patients undergoing Shoulder/Hip/Knee Arthroplasty surgery while maintaining the same or better pain…
- Conditions
- Post-operative Pain, Acute, Opioid Use, Unspecified, Arthroplasty Complications, Knee Osteoarthritis
- Trial name
- NCT06469177
- Testing
- Pain Coach App
- Where
- Canada
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Perioperative Care, Chronic Post-operative Pain
Optimized Acute Pain Control With Parecoxib in Uniportal Video-assisted Thoracoscopic Surgery.
Chronic pain after thoracic surgery has been a bothering problem since the era of thoracotomy. The prevalence of chronic pain no matter in thoracotomy or video-assisted thoracoscopic surgery is about 30 to 47%.
- Trial name
- NCT05150431
- Testing
- Parecoxib
- Where
- Taiwan
- Volunteers
- 58 people
- Sponsor
- National Taiwan University Hospital
Procedural Sedation
Intranasal Ketamine and Midazolam Mixture for Procedural Sedation in Children With Mental Disabilities:
Ketamine and Midazolam are well known sedative drugs that can be given through different routes such as intravenous, intramuscular, oral, rectal and intranasal route.
- Trial name
- NCT03860831
- Testing
- Ketamine + midazolam
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University