Clinical trials: Pain Management and Care
Carcinoma
Pain and Fatigue Study
Patients with advanced cancer who are undergoing chemotherapy and who report pain and fatigue at intake in the past 24 hours or at a level 2 or higher of pain or fatigue at a 3 or higher on a 10-point scale will be assigned…
- Trial name
- NCT00006253
- Testing
- Nurse, Non-nurse coach
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Michigan State University
Burns, Burn Wound
Virtual Reality Adjunct for Procedural Pain and Anxiety Management in Burn Wound Care
This randomized controlled trial is designed to evaluate the efficacy of immersive virtual reality (VR) as an adjunct to standard analgesia during dressing changes in adult burn patients.
- Conditions
- Burns, Burn Wound, Procedural Pain, Anxiety Acute
- Trial name
- VR-Burn (NCT06913270)
- Testing
- Immersive Virtual Reality Distraction (IVRD), Nature Video Distraction (NVD)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al Hayah University In Cairo
Pain, Pain Acute
The PainSMART Research Program: Evaluating a Pain Education Strategy for Patients Seeking Primary Care Physiotherapy
The goal of this clinical trial is to test the PainSMART-strategy in a population of patients seeking primary care physiotherapy for pain related to muscles, joints and bones, so called musculoskeletal pain.
- Conditions
- Pain, Pain Acute, Pain, Chronic, Self Efficacy
- Trial name
- PainSMART (NCT06187428)
- Testing
- PainSMART-strategy, Usual physiotherapy management
- Where
- 6 sites in Sweden
- Volunteers
- 494 people
- Sponsor
- Kajsa Johansson
Central Nervous System Diseases
Dexmedetomidine in Patients After Intracranial Surgery
Dexmedetomidine is a highly selective a2-adrenoreceptor agonist that produces dose-dependent sedation and analgesia without respiratory depression.
- Trial name
- NCT01445639
- Testing
- Dexmedetomidine, Normal saline
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Capital Medical University
Substance Withdrawal Syndrome
Opioids Withdrawal Syndrome in Critically Ill Patients: a Multicenter Prospective Cohort Study
Critically ill patients who are mechanically ventilated may require prolonged administration of sedatives and analgesics. Their prolonged use has been associated with withdrawal symptoms upon rapid weaning in critically ill…
- Trial name
- WAAICUP (NCT02318290)
- Testing
- Opiates
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Pain Management, Nursing Homes
Improving Pain Management in Nursing Homes: A Research Project to Enhance Care Practices
This study aims to improve the way pain is managed in nursing homes. It focuses on training staff, creating better systems to track pain, and involving residents and their families in decision-making.
- Conditions
- Pain Management, Nursing Homes, Elderly, Pain
- Trial name
- NCT06984042
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Centre Hospitalier de Gonesse
Postpartum Pain, Episiotomy Pain
Skin-to-Skin Contact, Cheek Contact and Episiotomy Pain Control
This randomized controlled trial aimed to evaluate the effects of skin-to-skin contact and kangaroo care on pain control during and after episiotomy repair following vaginal birth.
- Conditions
- Postpartum Pain, Episiotomy Pain, Postpartum Care
- Trial name
- NCT07471724
- Testing
- Skin-to-Skin Contact, Cheek-to-Cheek Contact
- Where
- Turkey (Türkiye)
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Ege University
Nociceptive Pain
Guiding Sufentanil Administration With Skin Conductance in Mechanically Ventilated Intensive Care Patients
Opioid administration in mechanically ventilated patients in the intensive care unit (ICU) is essential to maintaining patient respiratory and hemodynamic stability.
- Trial name
- NCT04696016
- Testing
- Skin conductance guided antinociception, Standard care antinociception
- Volunteers
- 30 people
- Sponsor
- Erasme University Hospital
Chronic Pain, Chronic Nonmalignant Pain
Chronic Pain Self-Management With Integrative Yoga Therapy (IYT)
The purpose of this study was to evaluate efficacy of chronic pain self-management program in community settings to adopt Integrative Yoga Therapy (IYT).
- Trial name
- NCT04313426
- Testing
- Integrative Yoga Therapy
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- Aarogyam UK
Post-Dental Gingival Pain, Gingival Swelling
Efficacy and Safety of HA35 Gel for Post-Dental Gingival Pain and Swelling
This is a prospective, single-arm, open-label, pilot clinical study to evaluate the efficacy and safety of 10% high-concentration 35 kDa hyaluronan (HA35) gel delivered via gel-soaked cotton balls in patients with gingival pain…
- Conditions
- Post-Dental Gingival Pain, Gingival Swelling, Postoperative Oral Pain, Dental Procedure-Related Discomfort
- Trial name
- HA35 (NCT07584655)
- Testing
- 10% High-Concentration 35 kDa Hyaluronan (HA35) Oral Topical Gel
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nakhia Impex LLC
Pain, Perioperative
Study To Investigate The Effectiveness Of Pregabalin For Management Of Patients Undergoing Total Hip Replacement
The purpose of this study is the investigate if pregabalin started a day before surgery and continued for 14 days post-operatively can reduce post-operative pain, relieve pre- and post-operative anxiety and sleep disturbances.
- Trial name
- NCT00905437
- Testing
- Pregabalin
- Where
- 7 sites in India
- Volunteers
- 72 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Low Back Pain
The Costs and Effectiveness of Cognitive Functional Therapy for People with Persistent Low Back Pain in Coventry.
Previous studies have shown Cognitive Functional Therapy (CFT) results in sustained clinically important improvements compared to a variety of interventions for persistent low back pain (LBP).
- Trial name
- NCT06161753
- Testing
- Cognitive Functional Therapy
- Where
- United Kingdom
- Volunteers
- 61 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Anxiety, Pain
Hypnotic Communication To Reduce Anxiety And Pain During Prostate Biopsy (HYCapp)
This single-centre randomized controlled study (HYCapp) will evaluate whether "hypnotic communication" (a structured, non-drug communication technique delivered by health professionals trained in clinical hypnosis) can reduce…
- Trial name
- HYCapp (NCT07476547)
- Testing
- Hypnotic Communication, Routine Prostate Biopsy
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Pain, Postoperative
An Efficacy and Safety Study to Compare Fentanyl Ionsys and Routine Care With Intravenous (IV) Morphine Patient-controlled Analgesia (PCA) in Participants Who Have Undergone Elective Major Abdominal or Orthopedic Surgery
The purpose of this study is to evaluate the mobilization characteristics, clinical use, safety and Ease of Care (EOC) of a fentanyl Iontophoretic Transdermal Patient Controlled Analgesia (PCA) system (Ionsys) and morphine…
- Trial name
- NCT00766506
- Testing
- Fentanyl IONSYS, Morphine IV PCA
- Where
- 7 sites in United Kingdom
- Volunteers
- 108 people
- Sponsor
- Janssen-Cilag Ltd.
Abdominal Pain Care
Improving Pain Management for Older Adults in the Emergency Department (ED)
The goals of this exploratory study are to determine the feasibility of integrating electronic clinical decision support into routine clinical pain care for adults in the ED setting and gather data on whether or not such clinical…
- Trial name
- NCT01962610
- Testing
- ePCA and Pain keycept intervention
- Where
- United States
- Volunteers
- 4,693 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Surgery-Complications
Factors Influencing PAP and Its PM Among Patient Undergoing Elective Surgeries at Tertiary Care Hospital Mardan
Postsurgical acute pain is a critical factor impacting recovery, patient satisfaction, and the risk of complications in surgical patients.
- Trial name
- NCT06768866
- Testing
- Gruop 1
- Where
- Pakistan
- Volunteers
- 386 people
- Sponsor
- Superior University
Chronic Low-back Pain, Patient Activation
Self-Management of Chronic Low Back Pain: Targeting Patient Activation
Patients with chronic low back (cLBP) pain report reduced physical function and ability to participate in social roles and are more likely to use opioid pain medications.
- Trial name
- NCT06236529
- Testing
- Health Behavior Change Counseling, Self-management program
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Johns Hopkins University
Obstetric Anesthesia Care
Obstetric Anaesthesia And Analgesia Month Attributes - International
A national survey of current practices, preferred drug and technique choices for obstetric anesthesia and analgesia in Czech Republic and Slovak Republic.
- Trial name
- OBAAMA-INT (NCT02380586)
- Testing
- Obstetric anesthesia and analgesia
- Where
- Czechia
- Volunteers
- 3,040 people
- Sponsor
- Brno University Hospital
Acute Pain
Rebooting Infant Pain Care: Using Machine Learning and Skin-to-Skin Contact to Exponentially Improve Neonatal Intensive Care Unit Practice
To address the current limitations related to infant pain assessment in the NICU, our international team of knowledge users and health/natural science/engineering/social science researchers have come together to build a machine…
- Trial name
- BabyAIBabyCalm (NCT05579496)
- Where
- 2 sites in Canada, United Kingdom
- Volunteers
- 400 people
- Sponsor
- York University
Pain, Chronic, Opioid Use Disorder
Pain and Opioid Management in Older Adults
The extent and depth of the ongoing opioid crisis are well known and many interventions are under way in the United States and other countries to alleviate its devastating impact on individuals and the society.
- Trial name
- RISE-OK (NCT05037682)
- Testing
- Dissemination and Implementation Research
- Where
- United States
- Volunteers
- 1,035 people
- Sponsor
- University of Oklahoma