Clinical trials: Pain Management and Care
Osteoarthritis, Pain
Celebrex Total Knee Arthroplasty Study
This study will investigate the benefits of administering celecoxib (Celebrex), a selective cyclooxygenase -2 (COX-2) inhibitor, in treating osteoarthritis (OA) subjects undergoing elective unilateral primary total knee…
- Trial name
- NCT00359151
- Testing
- Celecoxib
- Where
- 7 sites in United States
- Volunteers
- 22 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Labour Pains, Massage
Effect of Nonpharmacological Methods on The Active Phase Of Labour
The aim of this clinical trial is to evaluate the effects of methods such as exercise and hot showers applied during the active phase of labour on labour pain, labour duration, mode of delivery, newborn health, and the labour…
- Conditions
- Labour Pains, Massage, Exercise
- Trial name
- EFPCMUAPLBO (NCT07060339)
- Testing
- Exercise Programme, Hot Shower Programme, Combined Application (Exercise + Hot Shower)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Chronic Pain, Opioid Use
Developing and Pilot Testing an Opioid Tapering Protocol
This study proposes to pilot test an intervention to facilitate opioid pain reliever (OPR) tapering in primary care. The intervention will incorporate a clinician embedded within primary care to follow tapering dose schedules to…
- Conditions
- Chronic Pain, Opioid Use, Analgesia
- Trial name
- TapPro (NCT04257695)
- Testing
- TapPro
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Albert Einstein College of Medicine
Labor Pain
Intermittent Automated Devices for Labor Analgesia in Emilia Romagna
The study aims to determine whether the use of automated intermittent devices for labor analgesia could prevent the increase of instrumental deliveries, with same analgesia.
- Trial name
- PA-RER (NCT02710877)
- Testing
- Programmed Intermittent bolus, Manual epidural bolus, Levobupivacaine
- Where
- 3 sites in Italy
- Volunteers
- 671 people
- Sponsor
- University of Modena and Reggio Emilia
Pulpitis
Efficacy of Oral Prednisolone on Pain Reduction in Emergency Care of Acute Irreversible Pulpitis
Irreversible pulpitis is an inflammatory condition of the dental pulp, highly painful, representing one of the main reasons for consulting dental emergency.
- Trial name
- PULPISOLONE (NCT02629042)
- Testing
- Partial endodontic treatment under local and/or locoregional anesthesia, prednisolone
- Where
- France
- Volunteers
- 5 people
- Sponsor
- University Hospital, Bordeaux
Chronic Low-back Pain, Patient Activation
Self-Management of Chronic Low Back Pain: Targeting Patient Activation
Patients with chronic low back (cLBP) pain report reduced physical function and ability to participate in social roles and are more likely to use opioid pain medications.
- Trial name
- NCT06236529
- Testing
- Health Behavior Change Counseling, Self-management program
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Johns Hopkins University
Pain
Analgesic Efficacy of Hypnosis and Virtual Reality in Repetitive Pain Care
The originality of this study is the comparison of different distractibility techniques (hypnosis and virtual reality) in the very heterogenous contexts of pain management. This study will consider all types of care situations.
- Trial name
- PADIS (NCT04869553)
- Testing
- Management pain with distraction methods ABC, Management pain with distraction methods BCA, Management pain with distraction methods CAB
- Where
- 5 sites in France
- Volunteers
- 52 people
- Sponsor
- Lille Catholic University
Pain Management
Usage and Plan of Care Changes Due to Drug Screenings
The purpose of this minimal risk, observational survey is to document the accuracy, benefits, and how qualitative and quantitative results affect patients' plan of care.
- Trial name
- NCT02995278
- Testing
- Does not include a drug needing FDA approval and therefore it is not by definition, a Clinical Drug Trial as defined by FDA.
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Data Collection Analysis Business Management
Post Partum, Cesarean Birth
The Use of Photobiomodulation for Pain and Healing in Cesarean Section
Good incisional wound healing and postoperative pain are the primary concerns regarding cesarean delivery, as it can lead to serious complications and delayed recovery for patients.
- Conditions
- Post Partum, Cesarean Birth, Pain Management, Wound Care
- Trial name
- NCT07806526
- Testing
- Photobiomodulation (PBM), Standard Hospital Treatment
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Postoperative Care, Analgesia Assessment
Posthectomy in Pediatric Elective Surgery : a Comparison of Perioperative Analgesia Using Echo-guided Penile Block and Pudendal Block With neurostimuLation Technique
Context : Posthectomy is a surgical procedure that concerns around 30% of the male population, mainly in pediatrics. As this procedure is mainly performed on an outpatient basis, the implementation of an enhanced rehabilitation…
- Conditions
- Postoperative Care, Analgesia Assessment, Posthectomy, Postoperative Analgesia
- Trial name
- PinEAPPLE (NCT07191938)
- Testing
- Ultrasound guided penile block, Neurostimulation guided pudendal block
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Caen
Critically Ill
Managing Acute Pain in Critically Ill Non-communicative Palliative Care Patients
The purpose of this project is to test an innovative method for managing pain in acutely ill hospitalized patients who are not able to report their pain verbally to health care professionals.
- Trial name
- NCT02127086
- Testing
- Intervention Group
- Where
- United States
- Volunteers
- 377 people
- Sponsor
- University of Maryland, Baltimore
Pain, Pain Management
Ultrasound-guided Interscalene Block Versus Infraspinatus-Teres Minor Plane Block in Shoulder Arthroscopy
This study aims to compare the efficacy and safety of ultrasound-guided Interscalene block (ISB) versus Infraspinatus-Teres minor (ITM) interfacial plane block in shoulder arthroscopic surgery.
- Conditions
- Pain, Pain Management, Pain Management in Postoperative Care
- Trial name
- (ISB)-(ITM) (NCT07016386)
- Testing
- Group A: will receive an ultrasound-guided interscalene block (ISB), Group B:will receive an ultrasound-guided infraspinatus-teres minor (ITM) interfacial plane block
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Virtual Reality, Distraction
Virtual Reality (VR) Could Be a Good Alternative to Relaxing or Pain-relieving Medication
We want to investigate whether Virtual Reality (VR) could be a good alternative to the relaxing or pain-relieving medications that are often used to alleviate anxiety when patients undergo surgery under local anesthesia.
- Conditions
- Virtual Reality, Distraction, Elderly (people Aged 65 or More)
- Trial name
- NCT06649383
- Testing
- Virtual reality
- Where
- 2 sites in Sweden
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Pether Jildenstal
Coronary Disease, Cardiovascular Disease
Gender Differences in the Development, Treatment and Prognosis of Coronary Disease: A CALIBER Study
The initial manifestation of symptomatic coronary disease can range from angina (or symptoms of angina), unheralded acute coronary syndrome (ACS), or unheralded coronary death.
- Trial name
- NCT01164371
- Volunteers
- 1,758,584 people
- Sponsor
- University College, London
Intensive Care, Neonatal, Analgesia
Dexmedetomidine for Analgosedation to Newborn Infants During Neonatal Intensive Care
A prospective pharmacokinetic (PK), pharmacodynamic (PD) and pharmacogenetic (PG) observation study, including the PK/PD/PG relationship, on dexmedetomidine administered for analgesia and sedation to postsurgical and other…
- Conditions
- Intensive Care, Neonatal, Analgesia, Hypnotics and Sedatives
- Trial name
- NCT06482775
- Testing
- dexmedetomidine
- Where
- 2 sites in Sweden
- Sponsor
- Region Skane
Cystitis, Interstitial
Smartphone-based Self-care Education Program for Women With Interstitial Cystitis: Educational Remote IC Aide
To implement and assess clinical efficacy of a text message and multimedia-based program that (i) remotely delivers first- and second-line American Urological Association (AUA) treatments of IC/BPS; (ii) integrates treatment of…
- Trial name
- ERICA (NCT05260112)
- Testing
- ERICA
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Pennsylvania
Pain Management, Postoperative Care
The Effect of the Strategic Game Tangram on Postoperative Patient Outcomes
The aim of this study was to investigate the effects of playing tangram game after surgery on pain, fatigue and comfort levels in patients undergoing abdominal surgery.
- Conditions
- Pain Management, Postoperative Care, Nursing Care
- Trial name
- NCT07031271
- Testing
- Tangram game
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Aydin Adnan Menderes University
Monitoring Noxious Events Using EEG-Derived Pain Indices, Procedural Sedation and Analgesia
qNOX Response to Nociceptive Motor Events During Procedural Sedation
The goal of this observational study is to evaluate whether the CONOX monitor can detect pain during sedation in patients undergoing urological procedures.
- Conditions
- Monitoring Noxious Events Using EEG-Derived Pain Indices, Procedural Sedation and Analgesia, Monitored Anesthesia Care
- Trial name
- MO-NOX (NCT07413848)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara University
Chronic Pain, Cancer Pain
UDOPAL Study: Home-Based Interventional Approach to Pain Management in Home-Hospitalized Patients
The UDOPAL Study proposes an innovative home-based care approach for the management of pain in patients admitted to the Home Hospitalization Unit (UHD).
- Conditions
- Chronic Pain, Cancer Pain, Neuropathic Pain, Palliative Care
- Trial name
- UDOPAL (NCT07265492)
- Testing
- UDOPAL model
- Volunteers
- 100 people
- Sponsor
- Hospital de Manises
Pain
Assessment of Pain Monitoring With ANI/NIPE Monitor Program in Pediatric Cardiac Surgery Postoperative.
The main objective is to assess correlation between ANI/NIPE values and external evaluation COMFORT B scale during painful medical cares and during said comfort medical cares in intubated children admitted in pediatric intensive…
- Trial name
- ANI/NIPE (NCT02834481)
- Testing
- ANI/NIPE
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Toulouse