Clinical trials: Pain Management and Care
Back Pain, Back Pain With Radiation
Feasibility of Spinal Manual Therapy Interventions for a Future Clinical Study of Back Pain
This study aims to compare two different spinal manual therapy interventions of the back to determine if they are viable and acceptable for a future study investigating the treatment of patients with back pain.
- Conditions
- Back Pain, Back Pain With Radiation, Back Pain, Low
- Trial name
- NCT05778396
- Testing
- Active spinal manual therapy protocol, Control spinal manual therapy protocol
- Where
- Switzerland
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Fear, Pain Management
Influence of Preoperative Fear on Pain and Postoperative Outcomes
Fear of anesthesia plays a crucial role in the perioperative setting and can negatively affect recovery. The main objective is to assess the relationship between fear of anesthesia, surgeries, and hospitals and poorer…
- Conditions
- Fear, Pain Management, Anxiety, Complications of Surgical Procedures or Medical Care
- Trial name
- POSPoFe (NCT06785389)
- Testing
- Fear of anesthesia, surgery and hospitals scale, State-Trait Anxiety Inventory, Nummerical Rating Scale for postoperative pain
- Where
- Spain
- Volunteers
- 138 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Distal Radius Fractures
Mechanical Modalities vs. Standard Care for Edema and Pain Management After DRF Fixation
This single-blinded, randomized controlled trial (RCT) will evaluate the added benefit of mechanical modalities (continuous passive motion (CPM) and intermittent pneumatic compression (IPC)) when integrated into standard therapy…
- Trial name
- NCT06913920
- Testing
- Continuous Passive Motion (CPM), Intermittent Pneumatic Compression (IPC), Standard Therapy Program
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al Hayah University In Cairo
Labor Pain, Virtual Reality
Virtual Reality, Experience During Labour; a Qualitative Research (VIREL)
Childbirth is associated with labour pain and can be regarded as one of the most serious kinds of pain. Labour pain management methods include pharmacological and non-pharmacological methods.
- Conditions
- Labor Pain, Virtual Reality, Analgesia, Pain
- Trial name
- VIREL (NCT04858984)
- Testing
- Virtual Reality
- Where
- Netherlands
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Burns, Pain
Music Therapy and Pain Management in Burn Patients.
This is a randomized clinical trial studying the effectiveness of music therapy (i.e. MAR - Music-Assisted Relaxation) on pain intensity in burn patients hospitalized at the Adults Intensive Care Unit of the University Hospital…
- Trial name
- NCT04571255
- Testing
- Music-Assisted Relaxation
- Where
- Colombia
- Volunteers
- 82 people
- Sponsor
- Fundación Santa Fe de Bogota
Single Level Lumbar Decompression and Fusion Spine Surgery
Multimodal Analgesia vs. Routine Care Pain Management for Lumbar Spine Fusion Surgery: A Prospective Randomized Study
The purpose of this study is to determine if post-operative pain and rate of recovery are improved in patients undergoing spine surgery using MMA (multimodal analgesia) compared to usual analgsic care.
- Trial name
- NCT02202369
- Testing
- Multimodal Analgesia Treatment, Standard of Care Pain Management Protocol
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Perioperative Anxiety, Perioperative Pain Management
Evaluation of the Effectiveness of Virtual Reality as an Adjunct to Standard Care in Managing Perioperative Anxiety and Pain in Patients Undergoing Lower Limb Orthopedic Surgery Under Spinal Anesthesia
The goal of this clinical trial is to evaluate whether virtual reality (VR) can effectively reduce perioperative anxiety and pain in patients undergoing lower limb orthopedic surgery under spinal anesthesia.
- Conditions
- Perioperative Anxiety, Perioperative Pain Management, Hemodynamic Stability, Satisfaction
- Trial name
- NCT07134764
- Testing
- Virtual reality session
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Sfax
Opioid-use Disorder, Chronic Pain
Randomized Trial of ACT and a Care Management App in Primary Care-based Buprenorphine Treatment
The proposed IMPOWR Research Center at Montefiore-Einstein (IMPOWR-ME) will create a multidisciplinary and synergistic program of research to test multimodal treatments that address both chronic pain and opioid use disorder.
- Trial name
- NCT05039554
- Testing
- Acceptance and commitment therapy, Valera Smartphone Application, Treatment as Usual
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Albert Einstein College of Medicine
Nursing Caries, Pain, Postoperative
Effect of Foot Bath on Postoperative Sleep Quality and Pain
One of the most common problems in patients in the postoperative period is pain and the associated deterioration in sleep quality. Deterioration in sleep quality can cause pain to be perceived more severely.
- Conditions
- Nursing Caries, Pain, Postoperative, Sleep Deprivation
- Trial name
- NCT05705908
- Testing
- Hot Foot Bath 1, Hot Foot Bath 2
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Low Back Pain, Chronic Pain
Nonpharmacologic Pain Management in FQHC Primary Care Clinics
The goal of this study is to improve pain management and reduce opioid reliance for patients with chronic back pain in Utah Federally-Qualified Health Centers (FQHCs).
- Trial name
- BeatPain Utah (NCT04923334)
- Testing
- Brief Pain Teleconsult, Telehealth Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- University of Utah
Surgery, Critical Illness
Sedation Optimisation Strategy (S.O.S.) Ventilation
Use of sedatives and analgesics is common in mechanically ventilated patients hospitalized in Intensive Care Unit (ICU). That is called " sedation " and aimed to reduce both pain and anxiety and also to allow an effective and…
- Conditions
- Surgery, Critical Illness, Mechanical Ventilation Complication, Organ Dysfunction Syndrome
- Trial name
- NCT01486121
- Testing
- Therapy strategy
- Where
- 3 sites in France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Montpellier
Anesthesia, Consensus Development
Anesthesia Core Quality Metrics Consensus Delphi Study
To develop a ranked list of up to 20 metrics, which can be used to evaluate the quality of anesthesia, perioperative care, and acute pain management for adult inpatient non-cardiac surgical patients for use in quality improvement…
- Trial name
- NCT05386082
- Testing
- Modified Delphi process
- Where
- 3 sites in Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Music Therapy, Critical Care
Music Use for Sedation In Critically Ill Children
Stress induced by pain and anxiety is common in pediatric intensive care unit (PICU) patients and can impede the delivery of care as well as their recovery.
- Conditions
- Music Therapy, Critical Care, Analgesia, Ventilators, Mechanical
- Trial name
- MUSiCC (NCT03497559)
- Testing
- Music
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Alberta
Pain Management, Pain Assessment
Effectiveness and Implementation of a Clinical Pain Management Dashboard for the NICU
This study protocol describes a type 1 hybrid effectiveness-implementation study evaluating a clinical decision support dashboard for neonatal pain management in a tertiary NICU.
- Conditions
- Pain Management, Pain Assessment, Neonatal Intensive Care, Implementation Research
- Trial name
- NCT07629661
- Testing
- Implementation of clinical pain management dashboard
- Where
- Netherlands
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Abdominal Surgery, Thoracic Surgery
Parent/Nurse Controlled Analgesia in the Neonatal Intensive Care Unit
The aim of this study is to examine the safety and effectiveness of 2 morphine delivery systems for post-surgical neonates. The investigators hypothesize that this study will be feasible to conduct, and that neonates receiving…
- Trial name
- PNCA (NCT01823497)
- Testing
- Morphine
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Medical College of Wisconsin
Respiratory Depression, Sedation
Incidence of Opioid-Induced Respiratory Depression in Medical and Trauma Patients
The primary objective of this prospective, blinded observational study is to correlate assessment of sedation and respiratory status with capnography and pulse oximetry monitoring in hospitalized adult medical and trauma patients…
- Trial name
- NCT03647696
- Sponsor
- Poudre Valley Health System
Low Back Pain, Recurrent, Low Back Pain
Managing Non-acute Low Back Symptoms in Occupational Health: Two Trials
The purpose of this study is: Epidemiological part: characteristics of low back pain patients from a forestry company in Finland. Data is collected from occupational health databases and self administered questionnaires.
- Trial name
- NCT00908102
- Testing
- Moderate, Mild, Mild vs. NC
- Where
- Finland
- Volunteers
- 505 people
- Sponsor
- University of Helsinki
Procedural Pain
Intranasal Fentanyl in Preterm Infants Undergoing Peripherally Inserted Central Catheter Placement
The purpose of this feasibility clinical trial is to explore the role of intranasal fentanyl for pain associated with PICC placement in preterm infants.
- Trial name
- INFENT PICC (NCT06590870)
- Testing
- Fentanyl, Normal saline
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Mount Sinai Hospital, Canada
Dexmedetomidine, Ketamine
Safety and Efficacy of Esketamine - Dexmedetomidine Combination Versus Dexmedetomidine Monotherapy for Hyperactive Delirium in ICU Patients on Non-Invasive Respiratory Support (SEED-NIRS Trial): Study Protocol of a Randomized Controlled Trial
This investigator-initiated, randomized, controlled, single-blind, superiority trial aims to assess the efficacy and safety of esketamine combined with dexmedetomidine for the management of agitation or delirium in intensive care…
- Conditions
- Dexmedetomidine, Ketamine, Analgesia, Respiratory Therapy
- Trial name
- SEED-NIRS (NCT07377981)
- Testing
- Esketamine combined with dexmedetomidine, Dexmedetomidine
- Where
- China
- Volunteers
- 356 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Pain Management
Regional Block for Postoperative Free Flap Care
The purpose of this protocol is to evaluate the safety and efficacy of regional anesthesia for head and neck patients undergoing microvascular free flap reconstruction.
- Trial name
- NCT04080739
- Testing
- ropivicaine 0.2%
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham