Clinical trials: Pain Modulation
Myogenic Temporomandibular Joint Disorders, Myofacial Pain
Efficacy of PRP Injections in Reducing Pain for Myogenous TMD Patients
This study aims to evaluate whether intramuscular injections of platelet-rich plasma (PRP) are more effective than isotonic saline in reducing pain and improving jaw function in individuals diagnosed with myogenous…
- Conditions
- Myogenic Temporomandibular Joint Disorders, Myofacial Pain, Masseter Muscle
- Trial name
- NCT07606378
- Testing
- Saline (0.9% NaCl), Platelet rich plasma (PRP)
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska Institutet
Chronic Stable Angina, Periprocedural Myocardial Damage
MYocardial DAmage AND MIcrobiota STUDY
MYDA-MI study is a randomized, placebo controlled, double blind study performed in San Filippo Neri Hospital, Roma, Italy. The planned study duration is 18 months.
- Trial name
- MYDA-MI (NCT02908776)
- Testing
- Probiotic
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- San Filippo Neri General Hospital
Healthy, Musculoskeletal Pain
Pain Modulatory Profiles in Massage for Healthy Participants
One in ten adults experience widespread pain. Neck pain, for example, is a prevalent condition with a high rate of recurrence that affects between 10.4% and 21.3% of the population annually.
- Trial name
- NCT03490474
- Testing
- Pain Inducing Massage, Pain Free Massage, Coldpressor
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Florida
Adolescent Idiopathic Scoliosis, Cerebral Palsy
Pain Assessment in Children Undergoing Spine Surgery
Musculoskeletal (MSK) pain is one of the most common types of pain among children and adolescents. Recurring episodes of MSK pain conditions have a major impact on the daily lives.
- Trial name
- NCT04244760
- Testing
- Pain assessment for verbal patients, Pain assessment for non-verbal patients
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- Catherine Ferland
Osteoarthritis, Fibromyalgia
Assessing Central Aspects of Pain
BACKGROUND: Chronic pain continues for more than 12 weeks despite medication or treatment. Chronic pain is the main symptom of muscle and joint problems, rarely explained by damage to the muscle and joints alone.
- Conditions
- Osteoarthritis, Fibromyalgia, Chronic Low Back Pain, Inflammatory Arthritis
- Trial name
- AsCent (NCT06518278)
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- University of Nottingham
Vasectomy, Pain, Postoperative
Virtual Reality Technology for Vasectomy Pain Modulation
This study will evaluate whether or not wearing a virtual reality (VR) headset reduces pain and anxiety in patients undergoing vasectomy.
- Conditions
- Vasectomy, Pain, Postoperative, Anxiety Postoperative
- Trial name
- NCT05591274
- Testing
- SmileyScope Virtual Reality Headset
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Miami
Rumination, Chronic Pain
Modulation of Cortical Brain Activity During Attentional Control
The goal of this study is to determine whether an open-loop sham neurofeedback system can effectively modulate EEG alpha rhythms, which are associated with attentional control.
- Conditions
- Rumination, Chronic Pain, Fibromyalgia
- Trial name
- NCT06748976
- Testing
- Control
- Where
- Argentina
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Council of Scientific and Technical Research, Argentina
Chronic Pain, Headache
Placebo Impacts Sleep and Pain Modulation in Chronic Pain
The goal of this free-choice parallel design clinical trial is to examine the potential beneficial effects of using open-label placebo (OLP) in improving chronic pain related outcomes and sleep quality in people with…
- Trial name
- NCT06225817
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- University of Maryland, Baltimore
Fibromyalgia
EFFECTS OF A FULL SPECTRUM CANNABIS EXTRACT WITH DIFFERENT DOSES OF CBD AND THC ON THE MODULATION OF FIBROMYALGIA: A PILOT, MULTICENTER, OPEN LABEL CLINICAL TRIAL (FRIDINHA)
The Fridinha Project is a pilot, multicenter, open-label clinical trial that will investigate the therapeutic effects of different CBD and THC dosages in modulating fibromyalgia, a syndrome characterized by widespread chronic…
- Trial name
- NCT07498023
- Testing
- Cannabis
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Federal University of Latin American Integration
Healthy
Pain Inhibitory Effects of Other Pain Induced by Mechanical Pressure Compared to Electrical Stimulation and Cold Water.
The objective is to estimate the effects on pain thresholds of a painful mechanical stimulus on the upper trapezius compared to a painful electrical stimulus and a diffuse noxious stimulus using the cold water hand immersion test.
- Trial name
- NCT05730127
- Testing
- Conditioning stimulus
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Josue Fernandez Carnero