Clinical trials: Pain Monitoring
Cancer, Chronic Obstructive Pulmonary Disease (COPD
Detection of Electrodermal Activity in Pain 2
The goal of this study is to investigate the association between self-reported pain and electrodermal activity and to create an algorithm that detects pain and provides timely alarms for rising pain levels in patients with…
- Conditions
- Cancer, Chronic Obstructive Pulmonary Disease (COPD, Pain
- Trial name
- DEEP 2 (NCT06677593)
- Where
- Denmark
- Volunteers
- 37 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Healthy, Acute Pain
Detection of Electrodermal Activity in Pain 1
The goal of this study is to investigate the association between self-reported pain and electrodermal activity and to develop an algorithm that detects pain-related changes in electrodermal activity in healthy volunteers…
- Trial name
- DEEP 1 (NCT06678217)
- Testing
- Stroop task, Cold pressor test
- Where
- Denmark
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Hvidovre
Analgesia, Nociceptive Pain
Effect of ANI on Intraoperative Opioid Consumption
The aim of the study is to compare the analgesic nociception index (ANI), which is used to determine the dose of analgesic agent needed in the intraoperative period, with the conventional method in patients with erector spinae…
- Conditions
- Analgesia, Nociceptive Pain, Nerve Block, Pain
- Trial name
- NCT05106452
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Cesarean Section, Postoperative Pain After Cesarean Section
Nociception Level Index Monitoring During Cesarean Section
This prospective randomized controlled trial evaluated the effect of nociception level (NOL) index-guided intraoperative analgesia on postoperative pain management in patients undergoing elective cesarean section under general…
- Conditions
- Cesarean Section, Postoperative Pain After Cesarean Section, Pain Management
- Trial name
- NOL-CS (NCT07720440)
- Testing
- Nociception Level Index Monitoring, Standard Intraoperative Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istinye University
Pain, Postoperative
Wearable Electrocardiogram Monitoring Device and Smartphone Application in Perioperative Pain Management
This study aims to develop a wearable electrocardiograph monitoring device and smartphone application in perioperative pain management, also to evaluate relationship between postoperative pain and heart rate variability.
- Trial name
- NCT04686526
- Where
- China
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Nociceptive Pain, Anesthesia
Comparison of the Surgical Pleth Index and the Nociception Level Index in the Pediatric Population
This observational study aims to compare two nociception monitoring methods. The Nociception Level (NOL) index and the Surgical Pleth Index (SPI) in the pediatric population during general anesthesia.
- Conditions
- Nociceptive Pain, Anesthesia, Pediatric Anesthesia, Nociception Monitoring
- Trial name
- NOLvsSPI (NCT07084935)
- Testing
- Connecting all patients to the nociception level index(NOL) and the surgical pleth index (SPI), All patient will receive a tetanic stimuli (60mA, 100hz) of 5 seconds before start of incision
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Radboud University Medical Center
Anesthesia, Pain
Pupillometry Guided Remifentanil Administration In Pediatric Anesthesia
The aim of this prospective randomized study is to evaluate the impact of peroperative pupillometry monitoring on per and post-operative opioid consumption in pediatric anesthesia.
- Conditions
- Anesthesia, Pain, Child
- Trial name
- NCT02683837
- Testing
- Remifentanil, Pupillometry, Sevoflurane
- Where
- Switzerland
- Sponsor
- University Hospital, Geneva
Pain, Anesthesia
Analgesia-Nociception Index Guided Intraoperative Remifentanil Administration Versus Standard Practice:Evaluation of Perioperative Opioid Use
This study compares two groups of patients undergoing a gynecological surgey under general anesthesia: one group in which intraoperative analgesia is guided by the Analgesia-nociception index, and another group in which…
- Trial name
- MONIDOL-ANI (NCT03498820)
- Testing
- Analgesia Nociception Index, Remifentanil
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Evaluation of Blood Volume and Perceived Pain During Fingerstick Monitoring of Blood Glucose
The procurement of blood for SMBG, usually via a finger stick, is considered by many patients to be the most painful portion of diabetes therapy.
- Trial name
- NCT00741390
- Testing
- BD/33G, OTM / 33G, OTU/28G
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- Becton, Dickinson and Company
Patellofemoral Syndrome
Patient Self Monitoring of Physical Therapy Exercise
Our objective is to develop an IBEHR (Image-Based Electronic Health Record) to show patients how to reproduce at home the exercises prescribed by their physical therapist (PT) in clinic.
- Trial name
- NCT01781325
- Testing
- IBEHR
- Where
- United States
- Sponsor
- University of Washington
Anesthesia
Newborn Infant Parasympathetic Evaluation (NIPE) Index After Standardized Tetanic Stimulations Under General Anesthesia
NIPE monitor is the recently developed pediatric version of the ANI monitor, which is used in adults to monitor analgesia during general anesthesia.
- Trial name
- NIPESTIM (NCT04381637)
- Testing
- NIPE monitor, Tetanic stimulations
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Lille
Lumbar Herniated Disc
Evaluation of Minimally Invasive Microdiscectomy Versus Conventional Open Microdiscectomy For Lumbar Herniated Disc
Overall Objective: To evaluate pain and functional status of patients undergoing surgical correction for lumbar herniated disc, pre- and post-surgery, using subjective (VAS, Oswestry, PSQI, Patient Expectation), as well as…
- Trial name
- NCT00927056
- Testing
- Microdiscectomy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Critical Illness, Pain
Pervasive Sensing and AI in Intelligent ICU
Important information related to the visual assessment of patients, such as facial expressions, head and extremity movements, posture, and mobility are captured sporadically by overburdened nurses, or are not captured at all.
- Conditions
- Critical Illness, Pain, Delirium, Confusion
- Trial name
- NCT05127265
- Testing
- Video Monitoring, Accelerometer Monitoring, Noise Level Monitoring
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Florida
Chronic Pain, Hypercapnia
CO2 Monitoring Study
Opioids are an effective instrument for patients with acute and chronic pain. Their route of administration ranges from transdermal to subcutaneous application through to Intravenous Patient-Controlled Analgesia (IV-PCA).
- Conditions
- Chronic Pain, Hypercapnia, Quality of Life
- Trial name
- NCT02068274
- Where
- Switzerland
- Volunteers
- 17 people
- Sponsor
- Cantonal Hospital, Baselland
Breast Cancer
The Effect of Digital Technology-Supported Education on Patients Undergoing Breast Reconstruction After Mastectomy: A Randomized Controlled Study
The goal of this randomized, controlled study is to test the effectiveness of digital technology-supported education on patients undergoing breast reconstruction after mastectomy.
- Trial name
- NCT06166953
- Testing
- digital technology-supported education
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Baskent University
Postoperative Pain, Patient Controlled Analgesia
Monitoring Postoperative Patient-controlled Analgesia (PCA)
The introduction of Acute Pain Service (APS), 1985, specialized pain management could be offered to the inpatient care. An example of this is patient-controlled analgesia (PCA), which is a technique that is used mostly after…
- Conditions
- Postoperative Pain, Patient Controlled Analgesia, Surgery, Nurse-Patient Relations
- Trial name
- NCT03697278
- Testing
- Smith medical CADDsolis
- Where
- 2 sites in Sweden
- Volunteers
- 90 people
- Sponsor
- Pether Jildenstal
Cesarean Delivery
An Observational Study Measuring in a Non-invasive Approach the Nociception Level Index and Its Association With Pain and Anxieiy Perception Evaluated by Questionnaires, in Awake Women During Elective Cesarean Delivery Under Spinal Anesthesiaanxiety
The Nociception Level (NOL) Index is a multiparametric, non-invasive monitor that objectively assesses nociception by integrating several autonomic physiological signals.
- Trial name
- NCT07726316
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Michael Grach
Gynecologic Laparoscopic Surgery, Hysterectomy
Impact of Nociceptive-Level (NOL) Intraoperative Guided Analgesia During Gynecological Laparoscopic Surgery Under General Anesthesia
The aim of the present study is to show that the use of the NOL device in addition to the Standard of Care (based on mean arterial blood pressure and heart rate values) to guide the administration of opioids compared to the…
- Conditions
- Gynecologic Laparoscopic Surgery, Hysterectomy, Oophorectomy
- Trial name
- NOLGYN (NCT03776838)
- Testing
- Intravenous Fentanyl guided by SoC+NOL, Intravenous Fentanyl guided by SoC
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Pain, Anesthesia
NoL and BIS Monitoring on Patients Recovery and Safety After Surgery
So far, only vital signs (mostly, blood pressure and heart rate) helped the anesthesiologist to administer hypnotic agents or analgesics.
- Trial name
- CINAAMON (NCT03410485)
- Testing
- BIS index/NoL index, Variation of baseline mean arterial pressure
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Shoulder Pain, Chronic Pain
Feasibility of Near-infrared Spectroscopy to Measure Cortical Pain Pathway (Brain) Activation During Dry Needling
The benefit experienced by some patients when treated with dry needling,1 combined with the field-expedient nature of this intervention, make dry needling uniquely suited for the military healthcare environment.
- Conditions
- Shoulder Pain, Chronic Pain, Musculoskeletal Injury
- Trial name
- NCT04170803
- Testing
- Dry Needling
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Army-Baylor University Doctoral Program in Physical Therapy