Clinical trials: Pain Monitoring
Electroencephalography, Critical Care
Sedation Monitoring Using Frontal Electroencephalogram, Electromyogram and Hemodynamic Responses to Pain in Critical Care
Purpose: Assessing nociception and sedation in mechanically ventilated patients in the ICU is challenging, with few reliable methods available for continuous monitoring.
- Conditions
- Electroencephalography, Critical Care, Electromyography
- Trial name
- NCT04472247
- Testing
- Continuous EEG and EMG monitoring, with derived variables
- Where
- 2 sites in Finland
- Volunteers
- 30 people
- Sponsor
- University of Helsinki
Breast Neoplasms, Musculoskeletal Pain
Multicomponent Care for Aromatase Inhibitor-Related Musculoskeletal Symptoms
Breast cancer patients who receive endocrine therapy particularly aromatase inhibitors often experience aromatase inhibitors associated symptoms (AIMSS) such as joint and muscle pain along with stiffness and fatigue that can…
- Conditions
- Breast Neoplasms, Musculoskeletal Pain, Arthralgia, Musculoskeletal Diseases
- Trial name
- AIMSS-CARE (NCT07409948)
- Testing
- Multicomponent Care for Aromatase Inhibitor-Related Musculoskeletal Symptoms (AIMSS-CARE)
- Volunteers
- 88 people
- Sponsor
- Addis Ababa University
Intraoperative Neurophysiological Monitoring, Pain Management
Effect of a Bolus of Clonidine Systemically Administered on the Excitability of the Spinal Motoneurons of the Lower Extremity
The purpose of this study is to assess the effect of IV clonidine administration on lower limb spinal motoneuron excitability during standardized total intravenous anesthesia (propofol and remifentanil).
- Trial name
- EXCICLON (NCT02592915)
- Testing
- Clonidine hydrochloride, Single bolus of physiologic sodium chloride serum administered IV after induction and obtaining a stable anaesthetic level
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Queen Fabiola Children's University Hospital
Osteoarthritis, Knee
Bayer OA Knee Pain Pilot
The objective of this study is to investigate if MRI can be used to evaluated effect of knee artery embolization for knee osteoarthritis.
- Trial name
- NCT05349682
- Testing
- dynamic contrast enhanced MRI, geniculate artery embolization
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medical University of South Carolina
Pain
ADVANCE: Assessment for Defining Variability in Anesthesia Through Novel Clinical EEG
The present study is designed to compare prospectively whether sBIS, sEMG, or CVI variability (brain monitoring) can be used to predict unwanted intraoperative responses (high blood pressure, fast heart rate, tearing, etc.) to…
- Trial name
- CVI (NCT00689130)
- Where
- 4 sites in United States, Spain
- Volunteers
- 120 people
- Sponsor
- Medtronic - MITG
Nociceptive Pain, Monitoring, Intraoperative
Pain Assessment by Pupil Dilation Reflex (PDR) and Pupillary Pain Index (PPI) in Response to Noxious Stimulation in Anesthetized Adults
After conduction a pilot study, pupillary dilation reflex (PDR) is measured in response to nociceptive stimulation perioperatively.
- Trial name
- NCT03140241
- Testing
- PDR measurement
- Where
- Belgium
- Volunteers
- 34 people
- Sponsor
- University Hospital, Antwerp
Neuropathic Pain, Chronic Pain
Analysis of Selected Biochemical Parameters in Cerebrospinal Fluid and Peripheral Blood in the Treatment of Neuropathic Pain Using Spinal Cord Stimulation (SCS)
This project aims to identify key cells and molecules involved in the development and modulation of neuropathic pain treated with spinal cord stimulation (SCS).
- Conditions
- Neuropathic Pain, Chronic Pain, Spinal Cord Stimulation (SCS)
- Trial name
- NCT07153211
- Testing
- Immunological Factors
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Pawel Sokal
Pain, Monitoring, Intraoperative
Evaluation of the Pupil Dilation Reflex in Response to Noxious Stimulation in Anaesthetized Children. A Proof of Concept Trial
After conduction a pilot study, pupillary dilation reflex (PDR) is measured in response to nociceptive stimulation perioperatively in infants, children and adolescents.
- Trial name
- Pain@OR-kids (NCT03449732)
- Testing
- PDR measurement
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Antwerp
Chest Pain
Monitoring of Nontraumatic Chest Pain Borne by the "Department of Emergency Help Medicalized" (SAMU)
Support pre-hospital chest pain remains a difficult problem in both pre hospital regulation that when supported by the Mobile Services Emergency and Intensive Care (SMUR).
- Trial name
- DOLORES (NCT01236157)
- Where
- France
- Volunteers
- 1,816 people
- Sponsor
- French Cardiology Society
Respiratory Insufficiency, Metabolic Disease
Is Venous to Arterial Conversion (v-TAC) of Blood Gas Reliable in Critical Ill Patients in the ICU?
Objective: Arterial blood gas (ABG) is essential in the clinical assessment of potential acutely ill patients venous to arterial conversion (v-TAC), a mathematical method, has recently been developed to convert peripheral venous…
- Conditions
- Respiratory Insufficiency, Metabolic Disease, Acidosis, Alkalosis
- Trial name
- NCT03309423
- Testing
- venous to arterial conversion (v-TAC)
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Aalborg University
Rheumatological Injection, Pain Management
The Value of Standardized Respiratory Rate Monitoring Exercises During Rheumatological Injection Procedures
The goal of this clinical trial is to demonstrate the non-inferiority of standardized breathing control exercises on perceived pain during rheumatological injections procedures compared to standard care consisting of the addition…
- Conditions
- Rheumatological Injection, Pain Management, Respiratory Monitoring
- Trial name
- Respi-IR (NCT07172984)
- Testing
- Anesthesia, breathing group
- Where
- France
- Volunteers
- 136 people
- Sponsor
- Centre Hospitalier Metropole Savoie
Pain Measurement
Pain Monitoring of Herniated Disc Surgery Patients With Oura Ring
The objective of this research study is to show whether data given by Oura ring could be used to objectively measure patients pain and well-being before and after disc surgery.
- Trial name
- NCT05129007
- Testing
- Oura ring
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Tampere University Hospital
Angina, Unstable, Non-ST-Segment Elevation Myocardial Infarction (NSTEMI)
Rehabilitation After Acute Coronary Syndrome: a New Telemonitoring Strategy
Cardiac rehabilitation after an acute coronary syndrome is recognised in the latest guidelines and recommendations published by the major scientific societies as a class I indication.
- Conditions
- Angina, Unstable, Non-ST-Segment Elevation Myocardial Infarction (NSTEMI), ST-segment Elevation Myocardial Infarction (STEMI)
- Trial name
- NCT04942977
- Testing
- telemonitoring, Centre-based cardiac rehabilitation
- Where
- 2 sites in Spain
- Volunteers
- 67 people
- Sponsor
- Catcronic Salut SL
Analgesia, Scoliosis Idiopathic
Multidisciplinary Perioperative Care Pathway in Adolescents Undergoing Posterior Spinal Fusion Surgery
Posterior Spinal fusion (PSF) is one of the most invasive orthopedic surgical procedures in children and adolescents, often characterized by extensive tissue trauma, and severe postoperative pain.
- Conditions
- Analgesia, Scoliosis Idiopathic, Surgery, Postoperative Pain
- Trial name
- NCT04038229
- Testing
- Enhanced recovery pathway
- Where
- Belgium
- Volunteers
- 33 people
- Sponsor
- University Hospital, Antwerp
Stable Angina Pectoris
Evaluation and Comparison of Several Point-of-care Platelet Function Tests in Predicting Clinical Outcomes in Clopidogrel Pre-treated Patients Undergoing Elective PCI.
The purpose of this study is to investigate whether the level of Platelet Inhibition as assessed with five point-of-care platelet function assays correlates with clinical (periprocedural) outcomes such as Acute Myocardial…
- Trial name
- NCT00352014
- Where
- Netherlands
- Volunteers
- 1,000 people
- Sponsor
- R&D Cardiologie
Awareness Under Anesthesia
Monitoring Awareness and Pain Under Anesthesia Using a New EEG Based System
General anesthesia (GA) is the process of induction of unconsciousness in order to undergo surgery. Unlike sleep, a process of "anesthesia" is not related at all, 'Sleep' and does not include dreams - but is done by using drugs…
- Trial name
- NCT02938325
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Postoperative Pain
Monitoring Pupillary Reflex Dilatation for Optimized Postoperative Opioid Delivery Before Extubation.
The study will be designed to investigate the effect of pupillometry guided compared to non-PPI-guided postoperative pain therapy, conducted immediately at the end of surgery before extubation, on total postoperative opioid…
- Trial name
- NCT04594382
- Testing
- Pupillometry-Opioid treatment, Pupillometry -standardized opioid treatment
- Where
- Austria
- Volunteers
- 140 people
- Sponsor
- Medical University of Vienna
Regional Anesthesia Success, Pain Monitor During Anesthesia
Comparison of Caudal and Quadratus Lumborum Blocks With Pain Monitoring in Children
Study Type: Prospective, Randomized, Observational Clinical Study Primary Purpose: The primary objective of this study is to compare the analgesic efficacy of caudal block (CB) and quadratus lumborum block (QLB) in children…
- Conditions
- Regional Anesthesia Success, Pain Monitor During Anesthesia, Quadratus Lumborum Nerve Block, Caudal Block for Postoperative Analgesia
- Trial name
- NCT07398573
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ankara Etlik City Hospital
Pain
Acute Pain Oscillation in Electroencephalographic Monitoring Under General Anaesthesia
Chronic pain is an undesirable condition that impacts predominantly quality of life at all levels. Chronic pain might occur in healthy young patients when acute postoperative pain is undertreated and persists in time.
- Trial name
- EEGpain (NCT05873894)
- Testing
- EEG
- Where
- 2 sites in Spain
- Volunteers
- 50 people
- Sponsor
- Hospital General Universitario de Valencia
Intensive Care, Surgical, Anesthesia, General
Nociception Level Index as Monitorization of Pain at the Intensive Care
The aim of our study is to evaluate the effectiveness of a nociception monitor in providing adequate postoperative analgesia for patients needing critical care after surgery.
- Trial name
- NCT05762666
- Testing
- nociception level index monitor
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital