Clinical trials: Pain Palliation
Paediatric Oncology Palliative Care
Developing a Symptom List for Children With Cancer
Primary Objective The aim of this research study is to develop a comprehensive inventory of symptoms that occur in children with advanced cancer who are receiving a specialist palliative care service.
- Trial name
- NCT02726815
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Pain
Marijuana in Combination With Opioids in Palliative and Hospice Patients
Study Objectives: Primary reduction of pain and reduction in overall opioid utilization. Secondary improvement in overall patient well being, weight stabilization with increased appetite, improved oxygen saturation, improvement…
- Trial name
- NCT03233633
- Testing
- Medical Marijuana
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- The Connecticut Hospice Inc.
Cancer Pain, Erector Spinae Plane Block
Intermittent Erector Spinae Plane Block Via Subcutaneous Port for Cancer Pain
Cancer-related pain is a common and challenging problem in patients with lung cancer, often requiring long-term pain management.
- Trial name
- NCT07396558
- Testing
- Erector Spinae Plane Block
- Where
- Vietnam
- Volunteers
- 180 people
- Sponsor
- Hanoi Medical University
Cancer, Heart Failure
Virtual Reality as an Adjunct to Management of Pain and Anxiety in Palliative Care
Virtual reality has been shown to be an effective way to treat pain and anxiety in various different settings. Palliative care is an area of medicine that often deals with patients suffering from pain and anxiety.
- Conditions
- Cancer, Heart Failure, Copd, ALS
- Trial name
- NCT04138095
- Testing
- Virtual Reality
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Riverview Health Centre
Mild Traumatic Brain Injury, Headaches Posttraumatic
SMART Concussion Trial: Symptom Management vs Alternative Randomized Treatment of Concussion Trial
Given the rising rates of concussion in youth ages 10-19 and the significant proportion of young people who remain symptomatic for months following concussion, research evaluating the efficacy of multifaceted treatment options…
- Conditions
- Mild Traumatic Brain Injury, Headaches Posttraumatic, Neck Pain, Dizziness
- Trial name
- SMART (NCT05446597)
- Testing
- Symptom-specific Headache Treatment, Symptom-specific Dizziness &/or Neck Pain Treatment, Multimodal Concussion Treatment
- Where
- Canada
- Volunteers
- 62 people
- Sponsor
- University of Calgary
Bone Metastases
A Phase III Randomized Trial Comparing Stereotactic Body Radiation Therapy (SBRT) vs Conventional Palliative Radiation Therapy for Painful Bone Metastases
To compare increasing doses and different treatment schedules of stereotactic body radiation therapy (SBRT) against standard treatment scheduling.
- Trial name
- NCT06065449
- Testing
- Radiation Therapy
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Peripheric Neuropathy
Effect of Hilotherapy in the Management of Symptoms Related to Taxane-Associated Peripheral Neuropathy
In this randomized controlled study, it was aimed to determine the effect of hilotherapy on quality of life and comfort level in the management of symptoms related to taxane-associated peripheral neuropathy in patients with…
- Trial name
- NCT07345221
- Testing
- Hilotherapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Nuran Ayşen Pamir Aksoy
Pain, Pain Management
mHealth Intervention for Pain Self Management
This is a feasibility pilot test of a single-arm intervention to evaluate the beta version of an mHealth app-based behavioral intervention prior to scaling for a randomized controlled trial (RCT).
- Conditions
- Pain, Pain Management, Symptom Monitoring, Symptom Management
- Trial name
- PsyMINT (NCT07332377)
- Testing
- Mobile Health (mHealth) Intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Virginia Commonwealth University
Cancer
Care Partners: Web-based Support for Caregivers of Veterans Undergoing Chemotherapy
Given the growing strain on the Veterans Administration resulting from increasing caseloads of cancer patients, interventions are badly needed that assist patients in managing their illness, improve quality of life and avoid…
- Trial name
- NCT00983892
- Testing
- Caregiver website
- Where
- 2 sites in United States
- Volunteers
- 134 people
- Sponsor
- VA Office of Research and Development
Pain Cancer
Subcutaneous Versus Intravenous Morphine When Switching From Oral to Parenteral Route in Palliative Cancer Patients
The investigators aim to establish whether the intravenous or the subcutaneous route of administration has clinically significant advantages when parenteral administration of morphine is started with a combination of continuous…
- Trial name
- SIM (NCT05236647)
- Testing
- Morphine
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University Hospital, Akershus
Oncology, Cancer Pain
Pain ASsessment in CAncer Patients by Machine LEarning (PASCALE)
In cancer patients, the integration between anticancer therapies and palliative care is of fundamental importance. In this context, telemedicine can improve the quality of life (QoL) of chronic patients through self-management…
- Conditions
- Oncology, Cancer Pain, Quality of Life
- Trial name
- PASCALE (NCT04726228)
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- National Cancer Institute, Naples
Depression, Palliative Care
Methylphenidate for Depressed Cancer Patients Receiving Palliative Care
The purpose of this study is to determine whether methylphenidate is an effective treatment for depression and to document the safety and tolerability of methylphenidate in combination with an Selective Serotonin Reuptake…
- Conditions
- Depression, Palliative Care, Cancer, Mental Disorder
- Trial name
- NCT00129467
- Testing
- Methylphenidate, Selective Serotonin Uptake Inhibitor (SSRI)
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- US Department of Veterans Affairs
Cancer of Head and Neck, Pain, Face
Focused Ultrasound (FUS) Mesencephalotomy for Head & Neck Cancer Pain
This proposed pilot study will investigate the safety and initial effectiveness of focused ultrasound lesioning of the contralateral mesencephalon for severe, opioid-resistant pain associated with head and neck cancer
- Conditions
- Cancer of Head and Neck, Pain, Face, Pain, Neck
- Trial name
- NCT03894553
- Testing
- ExAblate Neuro
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Jeff Elias, MD
Neoplasm Metastasis, Pain
Virtual Reality for Advanced Cancer Pain
Background Pain is commonly experienced by people who are living with advanced (incurable) cancer. There is evidence to suggest virtual reality could help to relieve this pain: however, this evidence is poor quality with the…
- Conditions
- Neoplasm Metastasis, Pain, Palliative Care
- Trial name
- VRcan (NCT06534580)
- Testing
- Virtual Reality
- Where
- 4 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- University College, London
Palliative Care
Acupuncture Intervention for AYA With Cancer
The aim of the study is to innovatively extend acupuncture research in adult oncology to adolescents and young adults (AYA) by piloting a tailored acupuncture protocol for pain management in AYA in the Children's Hospital of…
- Trial name
- NCT03516799
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Children's Hospital of Philadelphia
Aspiration; Syndrome
The Effect of Listening to Stories and Watching Cartoon Film on Pain in the Aspiration Process in Children Receiving Palliative Care
The aim of this study is to determine the effect of listening to fairy tales and watching cartoons on pain in the aspiration process in play-age children receiving palliative care.
- Trial name
- NCT06010771
- Testing
- Listening to fairy tales, Watching Cartoon Film
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Gamze Akay
Painful Bone Metastases, Breast Carcinoma
MRI Guided High Intensity Focused Ultrasound (HIFU) and ThermoDox for Palliation of Painful Bone Metastases
This study will evaluate treatment with High Intensity Focused Ultrasound (HIFU)in combination with ThermoDox (liposomal doxorubicin) is safe and effective in reducing pain for patients with painful bone metastases.
- Conditions
- Painful Bone Metastases, Breast Carcinoma, Non-small Cell Lung Cancer, Small Cell Lung Cancer
- Trial name
- NCT01640847
- Testing
- High Intensity Focused Ultrasound (HIFU) in combination with ThermoDox
- Sponsor
- Imunon
Neoplasm Metastasis
Pilot Study to Test the Feasibility and the Efficacy of the German Language Adapted PRO-SELF© Plus Pain Control Program
The purpose of this pilot study is to refine and test an advanced and adapted German version of the PRO-SELF© Plus Pain Control Program (PCP), an educational intervention directed at cancer pain patients and their families to…
- Trial name
- PEINCA (NCT00920504)
- Testing
- German PRO-SELF(c) Plus Pain Control Program (PCP), Standard Care
- Where
- Germany
- Volunteers
- 39 people
- Sponsor
- University Hospital, Basel, Switzerland
End of Life, Pain
Assessment of the Interest of ANI in the Non-communicating Patient in Palliative Care
Comfort evaluation is one of the major challenges in the palliative care setting, particularly when it comes to non-communicative patients.
- Conditions
- End of Life, Pain, Analgesia
- Trial name
- ANI-CARE (NCT05454202)
- Testing
- ANI
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Lille
Pain Management, Nurse
The Effect of Pain Management Education Program on Pain Management Self-Efficacy Among Nurses Caring for Palliative Care Patients: A Quasi-Experimental Study
The goal of this quasi-experimental research designed as a single-group pre-test post-test model is to evaluate the effect of an educational intervention aimed at improving the pain management self-efficacy of nurses providing…
- Conditions
- Pain Management, Nurse, Self Efficacy, Palliative Care
- Trial name
- P-EASE (NCT07685665)
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University