Clinical trials: Pain Reduction, open to volunteers
Dental Anxiety in Children, Dental Pain
Kaleidoscope Compared to Tell-Show-Do for Reducing Children Pain and Anxiety During Pulp Therapy
The goal of this clinical trial is to investigate if Kaleidoscope glasses help children feel less pain and worry during dental work. It will also explore if these glasses help children feel more comfortable with the dentist.
- Trial name
- NCT07595731
- Testing
- behavior management using Kaleidoscope glasses (SOL, country of origin: China)., behavior management using the Tell-Show-Do technique and Kaleidoscope glasses (SOL, country of origin: China)., behavior management using the Tell-Show-Do technique.
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpotomies Primary Teeth, Anxiety
Dental Game Impact on Kids' Pulpotomy Pain and Anxiety
The aim of this study is to evaluate the effect of a dental simulation game on reducing pain and anxiety during primary teeth pulpotomy.
- Conditions
- Pulpotomies Primary Teeth, Anxiety, Pain
- Trial name
- Electronic (NCT07072559)
- Testing
- dental simulation game, tell show do
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Preventing Propofol Pain on Injection
Comparative Efficacy of IV Parecoxib vs Lidocaine in Reducing Propofol Injection Pain
Propofol is the most popular IV anaesthetic agent used for induction, however one of its known side effects is causing pain on injection, the gold standard method in preventing this pain is using lidocaine prior to injecting…
- Trial name
- NCT07116304
- Testing
- Lidocaine, a local anaesthetic., Parecoxib 40mg
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oman Medical Speciality Board
Chronic Pain, Chronic Insomnia
Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain
The goal of this study is to test two behavioral interventions for chronic insomnia in individuals with chronic pain and use prescribed opioid medication to treat their chronic pain.
- Conditions
- Chronic Pain, Chronic Insomnia, Opioid Use
- Trial name
- NCT06345872
- Testing
- CBT-I, Treatment as usual, Tapered Withdrawal
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Dental Pain and Sensation Disorder, Pain, Postoperative
Efficacy of Preoperative Administration of Gabapentin in 3rd Molar Dental Extraction.
This study is a double-blind, randomized, prospective, placebo-controlled single-center clinical research study in which 600 mg of gabapentin or placebo will be administered 2 hours preoperatively to 49 patients each undergoing…
- Trial name
- NCT04860141
- Testing
- Gabapentin 600mg
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Dental Fear and Anxiety
Assessing the Efficacy of Lemongrass and Lavender Aromatherapy in Reducing Dental Anxiety and Pain Associated With Local Anesthetic Injections in Pediatric Dental Patients
The goal of this clinical trial is to evaluate whether aromatherapy using lemongrass or lavender essential oils can reduce dental anxiety and pain perception in children aged 7-11 years undergoing local anesthetic administration…
- Trial name
- NCT07113080
- Testing
- lavender essential oil inhaled using face mask, lemongrass essential oil inhaled using face mask
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hiba Ahmed Eltayeb
Dental Pain, Facial Swelling
Comparing Obturation Using Bioceramic Nano-coated Gutta-percha With Bioceramic Sealer Versus Traditional Gutta-percha With Resin Sealer for Reducing Postoperative Pain and Swelling After Root Canal Treatment in Necrotic Single-rooted Teeth.
A randomized clinical trial will compare two root canal filling approaches in necrotic single-rooted teeth. The test group will receive bioceramic mono-block obturation using bioceramic nano-coated gutta-percha with a bioceramic…
- Trial name
- NCT07600099
- Testing
- Resin sealer with conventional gutta percha., Bioceramic sealer with bioceramic gutta-percha.
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain Management, Fear
Distraction Methods for Reducing Pain and Fear During Blood Draw in Children
Blood draw is a common invasive procedure that can cause pain and fear in children. This randomized controlled trial aims to compare the effects of pinwheel blowing, 3D hologram viewing, and sugar-free gum chewing on pain and…
- Trial name
- PED-DISTRACT (NCT07770191)
- Testing
- 3D Hologram Viewing, Pinwheel Blowing, Gum Chewing
- Where
- Turkey (Türkiye)
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Gülsev Kutman
Postoperative Pain
RCT to Test Regional Anesthesia Effect on Decreased Opiate Use
Examining use of strong pain medication with the use of perioperative anesthetic medications vs no use of the same perioperative medication
- Trial name
- NCT06989866
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Retinal Disease
Safety and Tolerability of IRX-101 in Patients Receiving Intravitreal Injections
This is a randomized, double-masked study to evaluate the tolerability and safety of IRX-101 versus 5% povidone-iodine (PI) in subjects receiving intravitreal anti-VEGF injections.
- Trial name
- COMFORT (NCT05750589)
- Testing
- IRX-101, Providone-Iodine
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- iRenix Medical, Inc.
Healthy, Behavior Management
Effect of Vibrasthetic Device on Pain Reduction During Local Anesthesia in Pediatric Patients
The goal of this clinical trial is to test if children aged between 6 and 14 years who are receiving a dental injection will feel less pain by using a vibration device applied to the injection site during the injection compared…
- Trial name
- NCT07306650
- Testing
- Vibrating device, Manual vibration
- Where
- Saudi Arabia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Peripheral Intravenous Cannulation, Pain Management
Is Pain Ease (New Formula) Safe and Effective in Reducing Pain Associated With Peripheral Intravenous Cannulation (PIV)?
The goal of this clinical trial is to learn if Pain Ease (new formula) is more effective than Nature's Tears in reducing pain associated with Peripheral Intravenous Cannulation (PIV), also known as an IV.
- Trial name
- NCT07821476
- Testing
- Sterile water, Vapocoolant spray
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gebauer Company
Abuse, Drug, Pain
THC and CBD: A Controlled Human Study Probing a Harm Reduction Strategy
The purpose of this research is to assess the impact of CBD on the effects of THC.
- Trial name
- THC-REDUX (NCT06859710)
- Testing
- THC, CBD 20 mg, CBD 40 mg
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Procedural Anxiety, Procedural Pain
Stress Ball and Empathic Verbal-Tactile Interventions for Reducing Anxiety and Pain in Mammography and Breast Ultrasonography: A Randomized Trial
This prospective, randomized controlled trial aims to determine the effects of stress ball use and empathic verbal communication with therapeutic touch on anxiety and pain perception in women undergoing mammography and breast…
- Conditions
- Procedural Anxiety, Procedural Pain, Breast Imaging
- Trial name
- NCT07562828
- Testing
- Stress Ball, Empathic Verbal-Tactile Intervention
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Myofascial Trigger Point Pain (MTrP)
High Intensity Laser Therapy (HILT) on Myofascial Trigger Points.
The aim of the study is to evaluate the effects of HILT on cervical flexibility and pain reduction in myofascial trigger points. The research will be carried out in the Physiotherapy laboratory of Andrés Bello University.
- Trial name
- HILT (NCT04445545)
- Testing
- High intensity laser therapy (HILT), Therapeutic Ultrasound (US), Stretching exercise
- Where
- 2 sites in Chile
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Quiropraxia y Equilibrio
Shoulder Pain, Abdominal Pain (AP)
Outcome of Active Aspiration Versus Simple Compression to Remove Residual Gas From Abdominal Cavity in Reducing Pain After Laparoscopic Cholecystectomy
The aim of this study is to compare outcome of active aspiration versus simple compression to remove residual gas from abdominal cavity in reducing pain after laparoscopic cholecystectomy.
- Trial name
- Lap Chole (NCT07299656)
- Testing
- Group A (Active Aspiration), simple compression
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Cesarean Section Pain
Postoperative in Cesarean Section, the Women Suffering from Pain Due to Wound "incisional Pain", High Level Laser One of Most Effective Methods That Promoting Healing and Decrease Pain so It Will Effective If Use in Decreasing Pain of Cesarian Section
High power laser is safe and effective methods, it's uses increasing one day after day in decreasing pain and promoting healing so its use in postoperative cesarian section will help mothers to overcome pain and return to ADLs…
- Trial name
- NCT06793293
- Testing
- High level laser, Non-steroidal anti- inflammatory drugs and antibiotics
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Reducing Pain With Nexplanon Implant Insertion
Vapocoolant Spray to Reduce Pain With Nexplanon Insertion
The purpose of this study is to assess if Pain Ease vapocoolant spray decreases pain associated with lidocaine injection during Nexplanon insertion procedures.
- Trial name
- NCT06933381
- Testing
- Vapocoolant spray
- Where
- 3 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Queen's Medical Center
Anxiety, Fear
Robotic and Aquarium Fish for Reducing Pain, Fear, and Anxiety in Children
This study aims to find out whether robotic fish and aquarium fish can help reduce pain, fear, and anxiety in children during painful medical procedures.
- Conditions
- Anxiety, Fear, Pain, Child
- Trial name
- NCT07769385
- Testing
- Robotic Fish
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Inonu University
Labor Pain
Left Lateral Position vs Supine Position to Reduce Active Labor Duration
This randomized clinical trial aims to compare the effect of the left lateral decubitus position versus the supine position on the duration of the active phase of labor in nulliparous women.
- Trial name
- DLI-SP (NCT07411352)
- Testing
- Left Lateral Decubitus Group, Supine Position Group
- Where
- Honduras
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras