Clinical trials: Pain Reduction
Opioid Abuse (Disorder), Opioid Analgesia
Reducing Opioid Use After Upper Extremity Surgery: Testing Lower Prescriptions and Pill Quantity
The goal of this clinical trial is to evaluate strategies for optimizing postoperative multimodal pain regimens and reducing opioid dependency in patients undergoing upper extremity surgery.
- Conditions
- Opioid Abuse (Disorder), Opioid Analgesia, Opioid Analgesic Adverse Reaction, Opioid Consumption
- Trial name
- NCT07750639
- Testing
- Naproxen, Acetaminophen, oxycodone
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- AdventHealth
Bladder Cancer
Enhancing Patient Comfort and Reducing Anxiety During Flexible Cystoscopy and Bladder Instillation in Bladder Cancer Patients: A Randomized Controlled Trial and Observational Study
The goal of this clinical trial is to learn if certain comfort-enhancing interventions can reduce pain and anxiety during flexible cystoscopy and bladder instillation in patients with bladder cancer.
- Trial name
- Flexi-comfort (NCT07204301)
- Testing
- Optimized Timing of Intravesical Lidocaine Gel, Calming Music During Procedure, Visual Distraction with Screen Content
- Where
- Canada
- Volunteers
- 378 people
- Sponsor
- Western University, Canada
Post Operative Pain Control, Narcotic Use
Sprix for Postoperative Pain Control Following Gynecologic Surgery
The ongoing opioid epidemic has altered both how physicians prescribe narcotics and patients' perceptions of those prescriptions.
- Conditions
- Post Operative Pain Control, Narcotic Use, Pelvic Organ Prolapse, Urinary Incontinence , Stress
- Trial name
- NCT04444830
- Testing
- Sprix
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Louisville
Trigger Finger, Pain
Using the Gate Control Theory of Pain to Decrease Pain During Trigger Finger Corticosteroid Injections
The goal of this clinical trial is to investigate a new noninvasive technique that patients may use to help reduce the pain that they experience during cortisone injections for trigger fingers.
- Trial name
- TFGCT (NCT06401473)
- Testing
- Ipsilateral Scratch Task, Motor Distraction Task
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Grand Canyon University
Skin Laxity
Feasibility Study: Compare the Effectiveness Between Two Pain Medications When Used Prior to Ultherapy™ Treatments
This study will compare the effectiveness of two pain medications for reducing discomfort during an Ultherapy treatment.
- Trial name
- NCT01708473
- Testing
- Advil, Lortab, Ulthera System Treatment
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Piriformis Syndrome
Comparative Effects of PIR and PFS on Pain, Hip ROM, and Disability in Piriformis Syndrome
This randomized clinical trial evaluates the effectiveness of Post-Isometric Relaxation (PIR) and Post-Facilitation Stretching (PFS) for managing pain, improving hip abduction and internal rotation, and enhancing functional…
- Trial name
- PIR-PFS RCT (NCT07255053)
- Testing
- Post Isometric Relaxation (PIR), Post Facilitation Stretching (PFS)
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Faisalabad
Elbow Fractures
Efficacy of the Buzzy System on Pain and Fear Reduction in Elbow Fracture Pin Removal
The goal of this study is to determine if the Buzzy System, a vibrating ice pack shaped like a bee reduces pain in removal of elbow fracture pin.
- Trial name
- NCT07520851
- Testing
- Flash Cards, Buzzy Ice pack
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Breast Cancer With Metastatic Bone Disease
Study Comparing Full-dose Radiotherapy Versus Reduced Dose in the Management of Bone Metastasis in Patients With Breast Cancer Receiving Zoledronic Acid
The aim of this prospective, randomized, open-label, multicentric clinical study is to assess the effícacy and tolerability of zoledronic acid 4 mg IV infused over 15 minutes every 4 weeks for a total of 6 infusions, in…
- Trial name
- NCT00172029
- Testing
- Zoledronic acid
- Where
- 7 sites in Turkey (Türkiye)
- Volunteers
- 116 people
- Sponsor
- Novartis
Pain
Reducing Pain With Focused Music Listening
Pain-reducing effects of music listening are well-established, but the effects are small and their clinical relevance questionable.
- Trial name
- PainMusic (NCT05267795)
- Testing
- Experimentally-induced pain
- Where
- Norway
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Persistent Postsurgical Pain, Breast Cancer Female
Preventing Persistent Pain and Reducing Depressive and Anxious Symptoms Following Mastectomy and Lumpectomy
The proposed study will be a pilot randomized controlled trial comparing treatment as usual (TAU) to treatment as usual plus a brief Acceptance and Commitment Therapy (ACT) intervention (TAU + ACT) with mastectomy and lumpectomy…
- Conditions
- Persistent Postsurgical Pain, Breast Cancer Female, Ductal Carcinoma in Situ
- Trial name
- NCT03430765
- Testing
- Acceptance and Commitment Therapy
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Katherine Hadlandsmyth
Chronic Pain
Mindfulness-based Stress Reduction (MBSR) for Reduction of Chronic Pain and Drug Therapie
Mindfulness-Based Cognitive Therapy (MBCT) combines ideas of traditional cognitive therapies with meditative practices aimed at cultivating mindfulness.
- Trial name
- Chronicare (NCT05843409)
- Testing
- Mindfulness-based stress reduction (MBSR)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda Socio Sanitaria Territoriale di Lecco
Pain
Evaluation of the Role of Tramadol 50mg as an Analgesic During Outpatient Hysteroscopy
The purpose of this study is to evaluate the role of Tramadol 50mg in reducing pain during outpatient hysteroscopy.
- Trial name
- NCT02068209
- Testing
- Tramadol
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Cairo University
Foot Pain
Reducing Foot Pain and Peak Plantar Pressure in Patients With Foot Pain
The research project aims to evaluate the effectiveness of OrthoFeet Hands-Free therapeutic shoes and prefabricated inserts in patients with foot pain.
- Trial name
- NCT06516900
- Testing
- OrthoFeet HandsFree Therapeutic Shoe
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Texas Rio Grande Valley
Pain in Preterm Neonates
Role of Oral Sucrose in Reducing the Pain to Orogastric Tube Insertion in Preterm Neonates
RESEARCH HYPOTHESIS Orally administered sucrose 2 minutes prior to the procedure of OGT insertion reduces pain associated with the procedure.
- Trial name
- NCT00949104
- Testing
- Sucrose, Double distilled water
- Where
- India
- Volunteers
- 120 people
- Sponsor
- Lady Hardinge Medical College
Low Back Pain
Dry Needling at the Thoracolumbar Junction on Measures of Sympathetic Outflow and Flexibility
Dry needling (DN) is becoming more frequently performed by physical therapists around the world to treat musculoskeletal pain. Dry needling is a form of trigger point therapy that evolved from using injections of local…
- Trial name
- NCT03630172
- Testing
- Dry needling
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Nova Southeastern University
Pain Management
Effectiveness of Bupivacaine, Ketorolac, Ketamine, vs Bupivacaine Alone in Reducing Postoperative Pocket Pain
Bupivacaine is the most widely used local anesthetic agent across majority of the Cardiac Implantable Electronic device (CIED) implant procedures in the United States.
- Trial name
- NCT05575999
- Testing
- Bupivacaine alone OR Bupivacaine-Ketorolac-Ketamine (BKK) Combination
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Cancer, Chemotherapy Induced Pain
Effect of Geranium Inhalation Aromatherapy on Pain and Blood Pressure in Cancer Patients Undergoing Chemotherapy
This randomized controlled trial aims to examine the effect of geranium inhalation aromatherapy on pain and blood pressure among Indonesian cancer patients undergoing intravenous chemotherapy.
- Conditions
- Cancer, Chemotherapy Induced Pain, Blood Pressure Changes in Cancer Patients, Chemotherapy Side Effects
- Trial name
- NCT07292844
- Testing
- Geranium Inhalation Aromatherapy
- Where
- Indonesia
- Volunteers
- 90 people
- Sponsor
- Universitas Muhammadiyah Surakarta
Neonatal Disease, Neonatal Disorder
Reducing Pain and Promoting Neurodevelopment Among Preterm Neonates
To determine the effects of multisensory stimulation and soft tissue therapy on procedural pain and neurodevelopment among neonates admitted to the NICU is the aim of the study.
- Trial name
- NCT04366102
- Testing
- Multisensory stimulation with soft tissue therapy, Routine hospital care
- Where
- India
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Carpal Tunnel Syndrome
Pain Reduction Produced by Different Treatments in Carpal Tunnel Syndrome
Pain reduction effects of the median nerve neural mobilization technique (a physiotherapy treatment) will be compared to those produced by a pharmaceutical treatment and the absence of treatment, in subjects who suffer carpal…
- Trial name
- NCT04119739
- Testing
- Median nerve neural mobilization, Ibuprofen Arginine
- Where
- Venezuela
- Volunteers
- 117 people
- Sponsor
- Francisco Unda Solano
Fibromyalgia
Effectiveness of Physical Exercise in Women With Fibromyalgia
Fibromyalgia (FMS) is a syndrome expressed by chronic widespread body pain which leads to reduced physical function and frequent use of health care services. Exercise training is commonly recommended as a treatment.
- Trial name
- NCT00498264
- Testing
- walking program, resistance muscular exercise
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Federal University of São Paulo