Clinical trials: Pain Response
Toothache
Benzocaine Gel Toothache Dose-Response Study
To evaluate the efficacy and safety of benzocaine gel products for the relief of toothache and to assess the subject's compliance with proposed label directions.
- Trial name
- NCT00474175
- Testing
- benzocaine
- Where
- 8 sites in United States
- Volunteers
- 577 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Diabetes, Peripheral Neuropathy
Lidocaine for Diabetic Peripheral Neuropathy
Diabetic nerve pain [painful diabetic peripheral neuropathy] is a common medical problem with few reliably effective treatments.
- Conditions
- Diabetes, Peripheral Neuropathy, Pain
- Trial name
- NCT02363803
- Testing
- lidocaine
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Washington University School of Medicine
Wound Care, Pain Intensity
Pain Medicine for Wound Care Procedures
This is a randomized double-blind study to determine if the administration of a small-dose of ketamine (an anesthetic)added to morphine (an opioid) contributes to reducing pain intensity during open wound care procedure (WCP)in…
- Conditions
- Wound Care, Pain Intensity, Hyperalgesia, Nausea
- Trial name
- NCT00701909
- Testing
- Morphine plus Ketamine
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 12 people
- Sponsor
- University of California, San Francisco
Painful Osteoarthritis of the Knee
A Study of the Efficacy and Safety of MEDI7352 in Participants With Painful Osteoarthritis of the Knee
This is a Phase IIb randomised, double-blind, placebo-controlled, dose-response study in participants with painful osteoarthritis (OA) of the knee.
- Trial name
- BESPOKE (NCT04675034)
- Testing
- MEDI7352
- Where
- 41 sites in Denmark, Estonia and 4 more
- Volunteers
- 345 people
- Sponsor
- AstraZeneca
Labor Pain
Epidural Neostigmine for Labor Pain
The purpose of this study is to see which dose of epidural neostigmine is the best additive to use with the numbing medication used in an epidural during labor.
- Trial name
- NCT00779467
- Testing
- Neostigmine, Bupivacaine, fentanyl
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Wake Forest University
Muscle Injury, Recovery
Efficacy of a Controlled Short-term Trial of Cannabidiol (CBD) Ingestion on Reducing Symptomatic Response and Facilitating Recovery After Induced Muscle Injury
We aim to determine the efficacy of a controlled short-term trial of CBD ingestion for reducing symptomatic response and facilitating recovery following induced muscle injury.
- Conditions
- Muscle Injury, Recovery, Pain Relief
- Trial name
- NCT04586712
- Testing
- Active CBD
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Florida
Fibromyalgia
Discontinuation Study of the Durability of Effect of Milnacipran for the Treatment of Fibromyalgia
The purpose of this study is to evaluate the durability of effect of milnacipran for the treatment of fibromyalgia in patients receiving long-term milnacipran treatment and to characterize the effects of milnacipran on multiple…
- Trial name
- NCT01014585
- Testing
- Milnacipran
- Where
- 58 sites in United States
- Volunteers
- 340 people
- Sponsor
- Forest Laboratories
Osteo Arthritis Knee
Study of Pain Catastrophizing
This study proposes to experimentally manipulate pain catastrophizing in order to investigate the neural mechanisms by which pain catastrophizing influences the experience of pain among non-Hispanic Blacks (NHBs) and non…
- Trial name
- SPAC (NCT03836586)
- Testing
- Cognitive-Behavioral Intervention, Pain Education
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Florida
Migraine
Efficacy and Tolerability of Rimegepant for the Prevention of Migraine in Adults With History of Inadequate Response to Oral Preventive Medications
This study is being conducted to evaluate the efficacy and tolerability of rimegepant for migraine prophylaxis in adults with a history of inadequate response to oral preventive medications
- Trial name
- NCT05518123
- Testing
- Rimegepant
- Where
- 111 sites in United States, Australia and 12 more
- Volunteers
- 962 people
- Sponsor
- Pfizer