Clinical trials: Pain Severity
Chronic Low Back Pain, Manual Therapy
Neuroscience Pain Education in Patients with Chronic Low Back Pain
The cognitive educational strategies such as neuroscience pain education, has been a popular and promising technique for treatment patients with chronic pain.
- Conditions
- Chronic Low Back Pain, Manual Therapy, Neuroscience Pain Education
- Trial name
- NCT03886636
- Testing
- neuroscience pain education, manual therapy, home exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Kutahya Health Sciences University
Meniscectomy, Osteo Arthritis Knee
AIR (Artificial Implant for Medial Meniscus Replacement) Study
The AIR Study is a multi-center, prospective, interventional clinical trial with the objective to evaluate the safety and performance of the Trammpolin® meniscus prosthesis system.
- Trial name
- AIR (NCT03696836)
- Testing
- Trammpolin® meniscus prosthesis
- Where
- 3 sites in Netherlands
- Volunteers
- 5 people
- Sponsor
- ATRO Medical B.V.
Neck Pain
Distance Learning and Neck Problems During Pandemic Period
For people who use computers a lot, Work-related musculoskeletal disorders of the neck are a common problem . It is generally agreed that the etiology of work-related neck disorders is multidimensional which is associated with…
- Trial name
- NCT04925999
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Misr University for Science and Technology
Cancer, Pain
A Study to Compare the Titration Efficacy and Safety of Control-released Oxycodone and Immediate-released Oxycodone in Patients With Moderate to Severe Cancer Pain
This study is to evaluate the efficacy and safety of a titration method by selects 10 mg control-released (CR) oxycodone tablet as background drug in combined with immediate-released (IR) oxycodone, compared to conventional…
- Trial name
- NCT03176199
- Testing
- Oxycodone
- Where
- 4 sites in Taiwan
- Volunteers
- 30 people
- Sponsor
- Taiwan Mundipharma Pharmaceuticals Ltd.
Nerve Block/Methods
Comparing Suprascapular Nerve Block and Interscalene Block for Post-thoracotomy Pain in Pediatric Patients.
The goal of this clinical trial is to determine which regional block provides superior analgesia in pediatric patients undergoing thoracic surgery.
- Trial name
- NCT07796399
- Testing
- Interscalene brachial plexus block, anterior Supraclavicular nerve block, Thoracic Epidural Analgesia (TEA) only
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Children's Cancer Hospital Egypt 57357
Pain
Sensory Distribution and Postoperative Analgesia of Ultrasound-Guided Interfascial Plane Blocks in Living Liver Donors
Living liver donor hepatectomy at our institution routinely includes ultrasound-guided interfascial plane blocks as part of postoperative analgesia.
- Trial name
- NCT07252063
- Testing
- interfascial plane block, patient controlled analgesia device, cutaneus sensory mapping
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bahçeşehir University
Abdominal Pain, Irritable Bowel Syndrome
Pain Processing and Pain Neuroscience Education in Children With Chronic Abdominal Pain
The primary scientific objective of the study entails examining whether altered endogenous pain inhibition is present in children with functional abdominal pain (FAP) and irritable bowel syndrome (IBS) compared with healthy…
- Trial name
- NCT02880332
- Testing
- Usual care, Pain Neuroscience education, Extra care
- Where
- Belgium
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Back Pain, Low
Effects of Myofascial Release Therapy and Endurance Training on Mechanical Back Pain
This study is a randomized clinical trial to determine the effects of myofascial release therapy versus endurance training of trunk extensor muscles on pain, disability and muscle endurance in patients with mechanical back pain.
- Trial name
- NCT05272098
- Testing
- Group A will receive myofascial release therapy + conventional physical therapy, Group B will receive endurance training of the trunk extensor muscles + conventional physical therapy
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Pain, Procedural, Pain, Postoperative
The Effect of Vibration and Cold on Pain and Anxiety Associated With Chest Tube Removal Following CABG
Removal of chest tubes after coronary artery bypass graft (CABG) surgery can cause severe pain and anxiety, which may negatively affect the recovery process.
- Conditions
- Pain, Procedural, Pain, Postoperative, Coronary Artery Bypass Surgery, Chest Tubes
- Trial name
- CABG (NCT06217263)
- Testing
- Vibration device, Vibration device&Cold application pack
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Istanbul University - Cerrahpasa
Chronic Postsurgical Pain, Chronic Post-surgical Pain
Prevention of Postsurgical Chronic Pain in Children and Adolescents (PREVENDOL)
Chronic postsurgical pain is a health problem with a great societal impact: approximately 20% of all children and adolescents undergoing surgery will develop chronic pain.
- Conditions
- Chronic Postsurgical Pain, Chronic Post-surgical Pain, Chronic Postoperative Pain, Chronic Post-operative Pain
- Trial name
- NCT06638437
- Testing
- Cognitive-behavioral therapy
- Where
- 3 sites in Spain
- Volunteers
- 125 people
- Sponsor
- University Rovira i Virgili
Rib Fractures, Pain Acute
Ultrasound Guided Serratus Anterior Plane Block in ED Patients With Rib Fractures
The goal of this clinical trial is to test the effectiveness of the Serratus Anterior Plane Block in patients with rib fractures.
- Conditions
- Rib Fractures, Pain Acute, Regional Anesthesia, Opioid Use
- Trial name
- NCT06299137
- Testing
- Serratus Anterior Plane Block, Ropivacaine injection
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rhode Island Hospital
Pain
Efficacy of Topical Lidocaine to Decrease Discomfort With Intranasal Midazolam Administration
The purpose of this study was to establish whether premedication with topical lidocaine would reduce the pain associated with IN midazolam administration in children.
- Trial name
- NCT02396537
- Testing
- Lidocaine, Midazolam, 0.9% Saline
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Abdomen, Acute, Other Acute Pain
Low Dose Ketamine (LDK) Versus Morphine for Acute Pain Control in the Emergency Department
The purpose of this study is to compare the safety and effectiveness of intravenous low dose ketamine (LDK) to the industry standard of morphine (MOR) in regards to controlling acute pain in the emergency department.
- Conditions
- Abdomen, Acute, Other Acute Pain, Flank Pain, Back Pain
- Trial name
- NCT01538745
- Testing
- Ketamine, Morphine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Brooke Army Medical Center
Digestive Oncology, Supportive Care
Donepezil for Oxaliplatin-induced Neuropathy Peripheral Neuropathy: Proof of Concept Study
The use of oxaliplatin in the treatment of colorectal or pancreas cancer induces (>75% of patients) severe sensorimotor neuropathy decreasing the quality of life of cancer survivors.
- Trial name
- DONEPEZOX (NCT05254639)
- Testing
- DONEPEZIL
- Where
- 34 sites in France
- Volunteers
- 77 people
- Sponsor
- University Hospital, Clermont-Ferrand
Brachial Plexus Blocks
Perineural Dexamethasone, Dexmedetomidine, or Their Combination to Reduces Rebound Pain After Supraclavicular Brachial Plexus Block
Dexmedetomidine, an α2 adrenoceptor agonist, and dexamethasone, a potent anti-inflammatory steroid, are commonly used, effective, and safe adjuvants to peripheral nerve block (PNB).
- Trial name
- NCT07299877
- Testing
- Group A (Dexamethasone), Group B (Dexmedetomidine), Group C (Dexamethasone + Dexmedetomidine)
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Al-Azhar University
Post Operative Pain, Postoperative Nausea and Vomiting
Postoperative Analgesia in Hip Arthroplasty
The goal of this clinical trial is to compare the analgesic effectiveness of two blocks in hip arthroplasty. The main question it aims to answer is -Which block is more efficient? Researchers will compare the suprainguinal fascia…
- Conditions
- Post Operative Pain, Postoperative Nausea and Vomiting, Hip Osteoarthritis
- Trial name
- NCT07153575
- Testing
- suprainguinal fascia iliaca block, Pericapsular nerve group (PENG) block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Balikesir University
Breast Cancer, Postoperative Pain
Liposomal Bupivacaine in Implant Based Breast Reconstruction
Objectives: 1. To evaluate the effect of liposomal bupivacaine on postoperative pain levels. 2. To evaluate the effect of liposomal bupivacaine on postoperative opioid consumption and opioid related adverse events. 3.
- Trial name
- NCT02659501
- Testing
- Liposomal bupivacaine, Bupivacaine with epinephrine, Morphine sulfate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Loma Linda University
Ankle Sprain
Proof-of-concept Study of NSAID Hydrogel Patch in Treatment of Acute Pain
The safety and the efficacy of the Esflurbiprofen Hydrogel Patch will be assessed in comparing with placebo in the treatment of acute pain due to ankle sprain
- Trial name
- NCT02729207
- Testing
- Esflurbiprofen Hydrogel Patch
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Teikoku Seiyaku Co., Ltd.
Mastectomy, Pain, Acute
Stellate Ganglion Block for Prevention of Post Mastectomy Depression
Complications after mastectomy include chronic pain and depression.
- Conditions
- Mastectomy, Pain, Acute, Pain, Chronic
- Trial name
- SGB (NCT06263907)
- Testing
- Stellate gangalion block
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Mansoura University
Neck Pain, Unilateral Blindness
Unilateral Blindness/ Unilateral Deafness-relation to Neck Pain
Neck pain is a common complaint in the general population affecting 10-15% of the general population. females more than men. Known risk factors are: Trauma, Repetitive lifting of heavy objects at work, driving vibrating vehicles…
- Conditions
- Neck Pain, Unilateral Blindness, Unilateral Deafness
- Trial name
- NCT00589407
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Hadassah Medical Organization
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