Clinical trials: Pain Severity
Brain Injury, Chronic
Hyperbaric Oxygen for Traumatic and Non-traumatic Brain Injury
The purpose of this study is to examine whether 40 hyperbaric oxygen sessions has effect on long-term symptoms after brain injury.
- Trial name
- HYBOBI2 (NCT01986205)
- Testing
- Hyperbaric Oxygen, Minimal pressure air
- Where
- 2 sites in United States
- Volunteers
- 49 people
- Sponsor
- Lindell Weaver
Hepatectomy, Analgesia, Epidural
Bupivacaine Levels in Liver Resection Patients
Bupivacaine is a local anesthetic commonly used to manage postoperative pain. Liver resection patients typically have an epidural catheter placed preoperatively through which they receive a continuous infusion of bupivacaine and…
- Trial name
- NCT03145805
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Jessica Burjorjee, MD, FRCPC
Pain, Chronic, Lumbar Radiculopathy
Study on the Use of Intraoperative Neurophysiological Monitoring in Spinal Cord Stimulator Trials
This is an observational pilot study. The spinal cord stimulator (SCS) procedure and neuromonitoring device is not under investigation. Neuromonitoring is typically performed on this patient population receiving SCS trials here.
- Conditions
- Pain, Chronic, Lumbar Radiculopathy, SCS
- Trial name
- SCS-Monitor (NCT05540756)
- Where
- United States
- Sponsor
- University of Chicago
Carotid Artery Disease, Stroke
Natural History of Carotid Atherosclerosis
A prospective study of 700 patients with coronary artery disease will undergo non invasive evaluation of their carotid arteries by ultrasound and microwave radiometry.
- Conditions
- Carotid Artery Disease, Stroke, Myocardial Infarction, Angina Pectoris
- Trial name
- NCT01521351
- Where
- Greece
- Volunteers
- 700 people
- Sponsor
- National and Kapodistrian University of Athens
Breakthrough Pain, Pain Due to Certain Specified Procedures
Procedural Pain in Palliative Care: Prevalence, Intensity and Treatment
This study aims to assess self reported procedural pain compared with background pain and evaluate pain intensity differences across six standard procedures.
- Conditions
- Breakthrough Pain, Pain Due to Certain Specified Procedures, Pain, Cancer
- Trial name
- NCT02437929
- Testing
- Mobilization, Positioning, Personal Hygiene Care
- Where
- Italy
- Volunteers
- 1,079 people
- Sponsor
- Antea Foundation
Appendicitis, Chronic Post-Procedural Pain
Pain and Discomfort After Appendectomy in Children
Appendectomy is the most common surgical procedure. Chronic abdominal pain is an uncommon complication following appendectomy. It is observed that pediatric patients who have undergone abdominal surgical procedure complained of…
- Trial name
- NCT03791229
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Sakarya University
Postoperative Pain
Dexamethasone or Clonidine as Adjuncts to Ropivacaine for Caudal Analgesia on Analgesia Duration in Children
Comparing the duration of pain relief from caudal analgesia when adjuncts like dexamethasone, clonidine, or saline (salt water) are added to ropivacaine.
- Trial name
- NCT02773602
- Testing
- Dexamethasone, Clonidine, Normal Saline
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Acute Pulpitis
Pain Measured by NRS and EEG in Acute Pulpitis
The aim of the proposed study is to investigate and comprehensively understand pain perception in patients diagnosed with symptomatic acute pulpitis who are resistant to inferior alveolar nerve block (IANB).
- Trial name
- NCT06526572
- Testing
- Brain wave analysis using electroencephalography (EEG)., Numerical rate Scale (NRS)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cleveland Dental Institute
Pain
Does Local Cooling of Testis in Patients With Epididymitis Relieve Pain and Reduce Quantity of Analgetics Intake?
The investigators propose to examine the effect of local cooling of testis in participants with acute epididymitis or orchiepididymitis on participants reported pain level and analgetics consumption.
- Trial name
- NCT02943772
- Testing
- Local hypothermia, Control
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Kaplan Medical Center
Total Shoulder Arthroplasty, Pain Management
ZYNRELEF vs Continuous Catheter for Pain Management Following Shoulder Arthroplasty
The purpose of this study is to determine if local intra-operative application of ZYNRELEF (topical medication) during shoulder replacement surgery improves pain control (as defined by opioid consumption after surgery) compared…
- Trial name
- NCT07280195
- Testing
- Zynrelef, Bupivacaine
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Washington University School of Medicine
Fibromyalgia, Whiplash
Diffuse Noxious Inhibitory Controls (DNIC): Nociceptive Modulation and Interaction With Neurocognitive Performance in Chronic Pain
Diffuse noxious inhibitory control In order to quantify central sensitization in chronic pain patients, the Diffuse Noxious Inhibitory Control (DNIC) model has been used frequently.
- Conditions
- Fibromyalgia, Whiplash, Chronic Pain
- Trial name
- NCT01172795
- Testing
- Relaxation session, Neurocognitive test battery
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
IUD Insertion Pain
Efficacy of Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Reduction During Intrauterine Device (IUD) Insertion in Outpatient Gynecology
Pain with intrauterine device (IUD) insertion is very common and there are few options for patients to help reduce this pain. Transcutaneous electric nerve stimulators (TENS) are a non-invasive procedure that may help reduce the…
- Trial name
- NCT06335823
- Testing
- Transcutaneous electrical nerve stimulation (TENS)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Postoperative Pain After Knee Arthroscopy
Effect of Pregabalin or Adductor Canal Block on Postoperative Analgesia
arthroscopically Anterior Cruciate Ligament Reconstruction (ACL) under spinal anesthesia were included in this study.
- Trial name
- NCT03530280
- Testing
- pregabalin (lyrica), adductor canal block including bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Ankara Diskapi Training and Research Hospital
Cardiac Surgery, Sternotomy
Pecto-Intercostal Fascial Plane Block Catheter Trial for Reduction of Sternal Pain
One of the most painful aspects of open heart surgery is the incision made through the skin and the sternum to access the heart (a "sternotomy").
- Conditions
- Cardiac Surgery, Sternotomy, Acute Pain
- Trial name
- NCT05054179
- Testing
- Ropivacaine 0.2% Injectable Solution Bolus, Normal Saline Infusion, Ropivacaine 0.2% Injectable Solution Infusion
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of British Columbia
Back Pain Lower Back, Magnetic Therapy
High Intensity Focused Electromagnetic Therapy on Pain and Quality of Life in Patients With Lumbar Disc Prolapse
Determine whether high intensity focused electromagnetic therapy has a significant effect on pain and quality of life in patients with lumbar disc prolapse.
- Trial name
- NCT07278596
- Testing
- High intensity focused electromagnetic therapy (HIFEMT), Stabilization exercise program
- Volunteers
- 60 people
- Sponsor
- Middle East University
Chronic Pain
Singing for Chronic Pain, a New Intervention for the Management of Chronic Pain
The aim of the project is to determine the feasibility of delivering a Singing for Chronic Pain (SCP) programme to patients with chronic pain attending a pain clinic.
- Trial name
- NCT04111861
- Testing
- Singing
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Royal Cornwall Hospitals Trust
Pain, Inflammation
Hyperbaric Oxygen Therapy Attenuates Central Sensitization Induced by a Thermal Injury in Human Volunteers (HBO)
The hypothesis of this investigation is to observe if HBO have an anti-inflammatory effect in humans induced by tonic heat stimulation.
- Conditions
- Pain, Inflammation, Hyperalgesia
- Trial name
- NCT02025686
- Testing
- Hyperbaric Oxygen, Normal ambient conditions
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Per Rotbøll Nielsen
Chemotherapy-induced Peripheral Neuropathy
A New Method for Identifying Sensory Changes in Painful Chemotherapy-induced Peripheral Neuropathy (CIPN)
The investigators propose that using the Diode Laser fiber type Selective Stimulator (DLss) in patients with chemotherapy-induced peripheral neuropathy (CIPN) will allow for the assessment of changes in small-fiber pain…
- Trial name
- NCT03687970
- Testing
- Brief Pain Inventory, Hospital Anxiety and Depression Scale, Neuropathic Pain Symptom Inventory
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Washington University School of Medicine
Post Cesarean Section Pain
Rectus Muscle Re-approximation at Cesarean Delivery
We include in our study 200 pregnant women, primigravidas, at term who underwent elective lower segment Cesarean section for the first time among the age group of 20 - 35 years.
- Trial name
- NCT03296969
- Testing
- cesarean section, Rectus muscle approximation
- Volunteers
- 200 people
- Sponsor
- Cairo University
Cervicogenic Headache
Ischemic Compression Technique Versus Jones Technique in Cervicogenic Headache Patients
The primary objective of the study is to determine the effects of Jones and Ischemic compression technique on pain, range of motion and disability in patients with cervicogenic headache.
- Trial name
- NCT06875869
- Testing
- Jones technique, Ischemic compression therapy
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
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