Clinical trials: Pain Severity
Angina Pectoris
To Assess the Anti-anginal Safety and Efficacy of Ivabradine in Subjects With Stable,Symptomatic Chronic Angina
Arms Assigned Interventions Experimental: Ivabradine Ivabradine 5 mg twice a day for first 4 weeks and 7.5mg twice a day when positive ETT and HR>60times/min or negative ETT and HR>80times/min of subjects.
- Trial name
- NCT02623569
- Testing
- Ivabradine, Atenolol
- Where
- 3 sites in China
- Volunteers
- 336 people
- Sponsor
- Xintong Pharmacy Company
Procedural Anxiety, Fear
Effects of Virtual Reality, Cold-Vibration Due To Intravenous Catheterization on Pain, Fear and Anxiety on Children
This is a randomized controlled trial. The aim of the study is to the effects of Virtual Reality and Local Cold-Vibration applications in reducing anxiety, fear and pain due to intravenous catheterization (PIC) in children aged…
- Conditions
- Procedural Anxiety, Fear, Procedural Pain, Child, Only
- Trial name
- NCT05435105
- Testing
- Virtual reality, Local cold-vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Cervical Pain
Effectiveness of Muscle Energy Technique (MET) Versus Stretching Exercises In Acute And Subacute Postural Neck Pain
This study will provide better evidence that which technique is more effective in acute and subacute postural neck pain. To find out the effectiveness of Muscle energy technique (MET) and stretching exercises in acute and…
- Trial name
- NCT06221566
- Testing
- Muscle Energy Technique, Stretching Exercises
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Dow University of Health Sciences
Hospital Acquired Infections
Comparative Effectiveness of Yakson Touch and a Dextrose-Sweetened Pacifier for Reducing Phlebotomy-Induced Pain in Term Neonates
To compare the effects of Yakson Touch, the Dextrose-Sweetened Pacifier, and routine care on physiological responses, pain intensity, and behavioral outcomes among term neonates undergoing phlebotomy.
- Trial name
- Yakson Touch; (NCT07788066)
- Testing
- Yakson Touch, Dextrose-Sweetened Pacifier
- Volunteers
- 2 people
- Sponsor
- RAK Medical and Health Sciences University
Pain, Acute
Methoxyflurane Analgesia for Paediatric Injuries
This is a randomised, double-blind, multicentre, placebo controlled study to evaluate the safety and efficacy of methoxyflurane (Penthrox®) for the treatment of acute pain in children and adolescents from 6 to less than 18 years…
- Trial name
- MAGPIE (NCT03215056)
- Testing
- Methoxyflurane, Normal saline
- Where
- 11 sites in Ireland, United Kingdom
- Volunteers
- 192 people
- Sponsor
- Medical Developments International Limited
Cerebral Palsy
Chronic Pain In a Greek Population With Cerebral Palsy
The aim of this observational, cross-sectional study is to effectuate a survey of chronic pain in a population of children, adolescents and adults with various forms of cerebral palsy in an educational and therapeutic setting in…
- Trial name
- CPPain (NCT04628156)
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- Cerebral Palsy Greece - Open Door
Clinically Diagnosed Endometriotic Patient Was Defined as a Woman Who Has Pelvic Pain and at Least One Evidence of PV or TVS
Effectiveness of Levonorgestrel-intrauterine System (LNG-IUS) Versus Depot Medroxyprogesterone Acetate (DMPA) in Treatment of Pelvic Pain in Clinically Diagnosed Endometriotic Patients
The primary objective : To compare effectiveness of pain control in endometriosis associated pelvic pain between LNG-IUS and DMPA The secondary objective : To compare vaginal bleeding pattern, side effect, continuation rate…
- Trial name
- NCT02894151
- Testing
- Depot medroxyprogesterone acetate, LNG-IUS
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Nephrolithotomy, Percutaneous, Anesthetics, Local
Efficiency of Erector Spinae Plane Block For Patients Undergoing Percutaneous Nephrolithotomy
Investigators' goal is to determine whether Erector Spinae Plane Block would provide a better analgesia, help mobilization and early discharge or increase satisfaction for patients undergoing Percutaneous Nephrolithotomy(PNL).
- Conditions
- Nephrolithotomy, Percutaneous, Anesthetics, Local, Nerve Block, Erector Spinae Plane Block
- Trial name
- NCT03652103
- Testing
- Ultrasound Guided Erector Spinae Plane Block Catheterisation, Bupivacaine 0.25% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Bozyaka Training and Research Hospital
Spinal Cord Diseases, Spinal Cord Injuries
An Open-Label Long-Term Study Of Pregabalin For The Treatment Of Central Neuropathic Pain
The purpose of this study is to assess the safety of the long-term use of pregabalin at doses up to 600 mg/day in patients with central neuropathic pain (post spinal cord injury pain, post stroke pain, and multiple sclerosis…
- Conditions
- Spinal Cord Diseases, Spinal Cord Injuries, Neuralgia, Pain
- Trial name
- NCT01202227
- Testing
- pregabalin
- Where
- 26 sites in Japan
- Volunteers
- 104 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Spondyloarthritis
SKIPPAIN - Speed of Onset of SecuKinumab-Induced Relief From Pain in Patients With AxIal SpoNdyloarthritis
The purpose of the study was to evaluate the efficacy and safety of secukinumab 150 mg compared to placebo in the early management (Baseline to Week 8) of spinal pain, disease activity, fatigue, and predictability of disease…
- Trial name
- SKIPPAIN (NCT03136861)
- Testing
- AIN457
- Where
- 66 sites in Belgium, Bulgaria and 15 more
- Volunteers
- 383 people
- Sponsor
- Novartis Pharmaceuticals
Irreversible Pulpitis, Tooth Extraction
Efficacy of Computer Controlled Intraosseous Anesthesia in Pediatric Dental Patients
To evaluate the effectiveness of intra-osseous anesthesia using Quicksleepr5 in pain elimination during dental treatment in maxillary and mandibular primary molars, compared to conventional anesthesia.
- Trial name
- NCT06245161
- Testing
- Quicksleeper5, conventional anesthesia
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Pain, Fear
Stress Ball Use During Cataract Surgery: Effects on Pain, Fear and Satisfaction
The aim of this study is to determine the effect of stress ball use during cataract surgery on patients' pain, fear, and satisfaction levels.
- Conditions
- Pain, Fear, Stress Ball, Nursing
- Trial name
- SBUDCS (NCT07452770)
- Testing
- Use of a stress ball during cataract surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Bezmialem Vakif University
Lumbar Spine Instability, Lumbar Spinal Stenosis
Modified-Thoracolumbar Interfascial Plane Block and Erector Spinae Plane Block Following Lumbar Instrumentation Surgery
Ultrasound (US)-guided peripheral nerve blocks have been used increasily due to the advantages of ultrasound in anesthesia practice. TLIP block is one of these nerve blocks performed under US guidance.
- Conditions
- Lumbar Spine Instability, Lumbar Spinal Stenosis, Lumbar Disc Disease, Lumbar Spine Degeneration
- Trial name
- NCT04189341
- Testing
- Erector spinae plane block (Group E), Modified-thoracolumbar interfascial plane block
- Where
- Turkey (Türkiye)
- Sponsor
- Medipol University
Labor Pain, Labor Long
The Effect of Fatima Ana's Hand on Birth Pain and Duration
Research Question: Does the Anastatica Hierochuntica have an effect on labor pain and duration? Methods: This study was planned as a a double blind randomized controlled experimental study.
- Trial name
- NCT05196841
- Testing
- Anastatica Hierochuntica
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Postoperative Pain
Ultrasound-guided Rectus Sheath Block In Children
Inguinal hernia repair is one of the common day-case surgery in children. The aim of this study is to compare the effects of ultrasound guided rectus sheath block and intravenous tramadol on peroperative anesthetic requirement…
- Trial name
- NCT02291705
- Testing
- rectus sheath block, Tramadol
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Acupuncture Analgesia, Acupuncture
ACU_Knee: Role of Acupuncture in Knee Prosthetic Surgery
Post-operative analgesia after total knee arthroplasty (TKA) has always been a challenge in the anesthesiological setting, having to combine good pain control and the need for early mobilization, both factors that can affect the…
- Conditions
- Acupuncture Analgesia, Acupuncture, Acupuncture Therapy, Total Knee Anthroplasty
- Trial name
- ACU_Knee (NCT07123805)
- Testing
- Acupuncture group
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Musculoskeletal Injury, Muscle Weakness
The ADAPTation to Therapeutic Resistance Training (ADAPT) Study
In 2018, the Academic Department of Military Rehabilitation (ADMR) published a pilot randomised controlled trial (RCT), demonstrating the feasibility and acceptability of integrating twice-daily blood flow restriction (BFR)…
- Trial name
- NCT05719922
- Testing
- Resistance Training
- Where
- 6 sites in United Kingdom
- Volunteers
- 150 people
- Sponsor
- Defence Medical Rehabilitation Centre, UK
Shoulder Impingement, Shoulder Pain
Comparison of Shoulder Stretches
Various stretches are used to lengthen the posterior shoulder capsule. No study has reported the comparison of the pragmatic posterior capsular stretch and cross body stertch
- Conditions
- Shoulder Impingement, Shoulder Pain, Adhesive Capsulitis, Rotator Cuff Tears
- Trial name
- NCT05324722
- Testing
- pragmatic posterior capsular stretch, cross body stretch
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Helping Hand Institute of Rehabilitation Sciences
Chronic Hip Joint Pain, Prearthritic Hip Disease
Movement Pattern Training in People With Intra-articular, Prearthritic Hip Disorders
Intra-articular, prearthritic hip disorders (PAHD) result in substantial dysfunction in young adults and are proposed precursors to hip osteoarthritis (OA).
- Trial name
- NCT02913222
- Testing
- Rehabilitation
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Washington University School of Medicine
Chronic Musculoskeletal Pain, Chronic Pain
Active Coping Program for Chronic Musculoskeletal Pain: A Controlled Clinical Study
Chronic musculoskeletal pain is a highly prevalent condition that is often associated with persistent pain, physical disability, and maladaptive psychosocial factors such as pain catastrophizing, fear of movement, and central…
- Trial name
- NCT07322822
- Testing
- Active Coping Program, Usual Care
- Where
- Spain
- Volunteers
- 169 people
- Sponsor
- Universidad de Extremadura
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