Clinical trials: Pain in Pediatric Dentistry
Dental Anxiety
Comparison of Virtual Reality and Mixed Reality Head-Mounted Displays for Dental Anxiety Control During Local Anesthesia in Children
Dental anxiety is a common problem in children and may negatively affect cooperation, pain perception, and treatment success during dental procedures.
- Trial name
- NCT07398105
- Testing
- Audiovisual Distraction Using Head-Mounted Display
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Abnormal Labial Frenum Frenectomy, Frenectomy
Pain After Diode Laser Frenectomy in Children
This prospective single-group clinical study aims to evaluate postoperative pain following diode laser-assisted frenectomy in pediatric patients and to assess the agreement between different pediatric pain assessment scales.
- Trial name
- PED-FREN (NCT07706023)
- Testing
- Diode Laser-Assisted Frenectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
the Impact of Modern Anesthesia Techniques Applied in Pediatric Dentistry on Physiological Parameters
Comparison of the Effects of Intraosseous Anesthesia Performed With the SleeperOne5 Computer-Controlled Device and Conventional Mandibular Nerve Block on Behavior and Pain Control During Anesthesia Administration in Children Aged 5-9
The injection stage is the most intense cause of anxiety during dental treatment in the pediatric patient group. It is aimed to keep the pain sensation at a minimum during this process.
- Trial name
- NCT07198997
- Testing
- digital anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Saglik Bilimleri Universitesi
Computer-controlled Local Anesthesia
Effectiveness of Computerized Local Anesthesia in Reducing Local Anesthesia in Reducing Child Pain During Injection
Pain and anxiety management during injection of local anesthesia are major challenges in pediatric dentistry. The injection of local anesthesia is often perceived by children as the most painful step , The introduction of…
- Trial name
- RCT (NCT07688018)
- Testing
- star pen, Conventional 4% articaine delivery by carpule syringe
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria
Pain Management
Ibuprofen as a Pain Management in Pediatric Dentistry
Abstract Introduction: Administration of non-steroidal anti-inflammatory drugs (NSAIDs) before tooth extraction may reduce post-surgical pain, but there is a lack of research.
- Trial name
- NCT04476069
- Testing
- IBUPROFEN
- Where
- Saudi Arabia
- Volunteers
- 56 people
- Sponsor
- Princess Nourah Bint Abdulrahman University
Anesthesia
Jet Injectors Versus Conventional Anesthetic Technique in Children
This clinical study was conducted to compare the needleless Comfort-in jet injector device and the conventional needle technique in terms of 1. Pain level during the administration of local anesthesia in children. 2.
- Trial name
- NCT06314984
- Testing
- Group I A (Conventional needle syringe), Group I B (Conventional needle syringe), Group II A (Comfort-in Jet Injector)
- Where
- Egypt
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Pain, Extraction, Tooth
Comparison of Pain Perception in A Group of Pediatric Patients Undergoing Maxillary Primary Molar Extraction Using A Novel Anesthetic Device Versus Traditional Infiltration
This study aims to compare the pain felt by children during tooth extraction using two different techniques for giving local anesthesia.
- Trial name
- SO5PED (NCT07124052)
- Testing
- SleeperOne 5, (Conventional Infiltration Anesthesia)
- Volunteers
- 2 people
- Sponsor
- Aya Hesham ElSayed Mohamed ElTanahy
Dental Fear, Anesthesia, Local
Effectiveness of Synapse Transcutaneous Electronic Nerve Stimulation (TENS) During Dental Procedures Among Children
Dental Fear and Anxiety (DFA) are at higher levels among children and often leads to avoidance of dental treatment. Negative experiences in the early years such as experience of pain during injections, fillings, or extractions…
- Conditions
- Dental Fear, Anesthesia, Local, Pediatric Dentistry
- Trial name
- NCT03779659
- Testing
- Synapse TENS device, Topical anesthetic gel
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston University
Dental Anxiety, Pain Management
Wand STA vs SleeperOne for Pediatric Local Anesthesia (WASO-Kids)
This randomized, single-blind, split-mouth trial compares the acceptance of two computer-controlled local anaesthetic delivery (CCLAD) systems - Wand® STA and SleeperOne⑤ - in children aged 4-9 years undergoing comparable…
- Trial name
- WASO-Kids (NCT07754851)
- Testing
- Computer-controlled local anesthetic delivery system (pressure-sensing, single-tooth anesthesia type), Computer-controlled local anesthetic delivery system (corded, pen-style electronic type)
- Where
- Greece
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Dental Anxiety, Pediatric Dental Patients
Effect of Music on Anxiety, Pulse Rate, and Pain During Fissure Sealant Application in Children
This study aimed to evaluate the effects of music on anxiety, heart rate, and pain perception in children during fissure sealant application, and to compare the effectiveness of clinician-selected and patient-selected music.
- Conditions
- Dental Anxiety, Pediatric Dental Patients, Dental Procedures, Pain Perception
- Trial name
- NCT07536828
- Testing
- Music intervention 1, Music intervention 2
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Nigde Omer Halisdemir University
Pain
Does Preventive Analgesia Improve the Outcome of Demerol-Vistaril Procedural Sedations in Pediatric Dentistry
All healthcare providers strive continually to improve the outcome of their treatment approaches. The investigators hypothesize that preventive analgesics administered before a child is sedated with a Demerol-Vistaril regimen…
- Trial name
- Analgesia (NCT01971853)
- Testing
- Oral Analgesics
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Local Anesthesia Injection Pain
Evaluation of Computer-controlled Local Anesthesia in Children - a Clinical Trial
The goal of this clinical trial is to learn if Computer Controlled Local Anesthetic Delivery (CCLAD) results in lower pain during local anesthesia administration for infiltration in the buccal region of the upper jaw in patients…
- Trial name
- NCT06785480
- Testing
- Computer Controlled Local Anesthetic Delivery (CCLAD), Conventional metallic syringe
- Where
- Belgium
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Inflamed and Infected Primary Molars in Children, Effectiveness of Buffered Local Anesthesia During Dental Extraction
Evaluate Buffering Local Anesthetic in Inflamed Teeth
This randomized, double-blinded, split-mouth clinical trial evaluates the effect of buffering local anesthetic with sodium bicarbonate in pediatric dental extractions.
- Trial name
- NCT07120594
- Testing
- Unbuffered lidocaine 2% with epinephrine 1:80,000, Buffered lidocaine 2% with epinephrine 1:80,000
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Latakia University
Dental Anxiety, Pain
Efficacy of Hypnosis in Anxiety/Pain Reduction in Children During Pulpotomies
Anxiety and pain are emotions that the child often experiences in the dental office, generating the appearance of negative, uncooperative and even disruptive behaviors during the treatment; these make it difficult for dental care…
- Trial name
- NCT03739346
- Testing
- Hypnosis, Tell, show, do technique
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alejandra Ramírez Carrasco
Dental Anxiety, Pain
SleeperOne vs. Conventional Infiltration: Pain Perception in Mandibular Primary Molar Extraction
This clinical trial is being conducted in the Department of Pediatric Dentistry, Faculty of Dentistry, Cairo University. The purpose of the study is to compare the pain perception and comfort of children during tooth extraction…
- Conditions
- Dental Anxiety, Pain, Pain Management, Extraction, Tooth
- Trial name
- SOTIMAN (NCT07156396)
- Testing
- SleeperOne®, dental Hitec, France, Conventional Infiltration
- Volunteers
- 28 people
- Sponsor
- Ameera Alaa Eldin Abdalazim Khalifa
Tooth Extraction, Dental Anxiety
Comparison of Needle-Free Injection and Conventional Syringe for Tooth Extractions in Children
The goal of this clinical trial is to learn whether a needle-free injection system can make tooth extraction less stressful for children than a conventional dental syringe.
- Conditions
- Tooth Extraction, Dental Anxiety, Procedural Pain, Anesthesia, Dental
- Trial name
- NCT07548892
- Testing
- Needle-Free Jet Injection System, Conventional Syringe Injection
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Pediatric, Radiography
Comparison of Post-operative Pain in Relation to Working Length Assessment by Electronic Apex Locator and Digital Radiography in Permanent Teeth Among Pediatric Patients
This randomized, double-blind clinical trial was conducted at the College of Dentistry, Jouf University, Kingdom of Saudi Arabia, between August 2024 and February 2025.
- Trial name
- NCT07181252
- Testing
- Working length of root
- Where
- Saudi Arabia
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Jouf University
Traditional Local Anesthesia, Computer-controlled Electronic Anesthesia
Pain and Anxiety in Pediatric Dentistry: Computer-Controlled vs. Traditional Anesthesia
The purpose of this clinical study is to evaluate how different local anesthesia techniques affect pain and anxiety levels in children undergoing dental treatment.
- Conditions
- Traditional Local Anesthesia, Computer-controlled Electronic Anesthesia, Dental Anxiety, Anxiety in Children
- Trial name
- NCT07156487
- Testing
- Digital Anesthesia with SleeperOne 5, Infiltration Anesthesia with a Metal Cartridge Syringe, Mandibular Block Anesthesia with a Metal Cartridge Syringe
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Dicle University
Pediatric Dentistry
Buffered Lidocaine in the Pediatric Dental Patient
Local anesthetic buffered with sodium bicarbonate has been suggested to reduce pain, discomfort and onset time of local anesthesia on injection into tissue, compared to non-buffered solutions.
- Trial name
- NCT04055116
- Testing
- Buffered Lidocaine
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Geisinger Clinic
Local Anesthetic Infiltration, Topical Anesthesia
Topical Cryoanesthesia Versus Benzocaine in Pediatric Dentistry
This clinical study tested and compared two ways (cold-base technique or "cryoanesthesia" and conventional benzocaine gel) to reduce pain from dental injections in children.
- Conditions
- Local Anesthetic Infiltration, Topical Anesthesia, Pain Perception
- Trial name
- No acronym (NCT07351383)
- Testing
- Local Anesthesia (lidocaine hydrochloride)
- Where
- Mexico
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí