Clinical trials: Painful
Pain
A Study of YZJ-4729 Tartrate Injection for the Treatment of Pain After Orthopedic Surgery
The primary objective is to evaluate the analgesic efficacy and safety of IV YZJ-4729 Tartrate Injection in patients with acute postoperative pain following Orthopedic surgery
- Trial name
- NCT06901830
- Testing
- YZJ-4729, Active Comparator: Morphine
- Where
- 21 sites in China
- Volunteers
- 150 people
- Sponsor
- Shanghai Haiyan Pharmaceutical Technology Co., Ltd.
Patellofemoral Osteoarthritis
Proximal and Distal Therapeutic Approach in Pain and Lower Limb Kinematic in People With Patellofemoral Osteoarthritis
This is a crossover study that will investigate the immediate effects of a proximal therapeutic approach (SERF strap) and a distal one (foot orthoses) on knee pain intensity, global change, symptoms, ease of performance and…
- Trial name
- NCT04332900
- Testing
- Elastic hip strap, Insole
- Volunteers
- 30 people
- Sponsor
- Universidade Federal de Sao Carlos
Somatoform Disorders
Stress and Health Interview for Primary Care Patients With Medically Unexplained Symptoms
The goal of this study is to test the feasibility and acceptability of providing an experiential assessment interview that targets emotional and stressful experiences in primary care.
- Trial name
- NCT02151500
- Testing
- Stress and Health Interview
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Wayne State University
Osteoarthritis Hip, Joint Disease
Mobilization With Movement in Patients With Osteoarthritis of the Hip
The concept of mobilization with movement, also referred to as a Mulligan mobilization, has not been studied in patients with hip osteoarthritis, subsisting questions about the possible effects in this population.
- Conditions
- Osteoarthritis Hip, Joint Disease, Musculoskeletal Diseases, Pathologic Processes
- Trial name
- MWM (NCT02390336)
- Testing
- Real mobilization-with-movement (MWM)
- Volunteers
- 40 people
- Sponsor
- Natália Maria Oliveira Campelo
Rotator Cuff Tear
Effects of Kinesiotaping on Muscular Activity, Mobility, Strength and Pain After Rotator Cuff Surgery
Kinesiotape (KT) is widely used in musculoskeletal rehabilitation as an adjuvant to treatment but minimal evidence supports its use.
- Trial name
- NCT03379636
- Testing
- kinesiotape
- Volunteers
- 39 people
- Sponsor
- Clinique Romande de Readaptation
Temporomandibular Disorders (TMDs)
Investigation of the Effects of Different Treatment Approaches in Jaw (Temporomandibular) Joint Disorders
Temporomandibular joint disorders (TMD) are common conditions that may cause jaw pain, limited jaw movement, and reduced quality of life.
- Trial name
- NCT07392671
- Testing
- Conventional Physiotherapy and Rehabilitation Program, Limbic-Oriented Manual Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University
Postoperative Pain Management in Total Knee Arthroplasty
Efficacy of an AFCN Proxy Block in Post-TKA Multimodal Pain Management
This randomized controlled trial evaluates the additive effect of Supra-Sartorial Subcutaneous Infiltration (SSSI) when performed in combination with intermittent adductor canal block (iACB) and posterior capsule local…
- Trial name
- NCT07191964
- Testing
- Supra-Sartorial Subcutaneous Infiltration (SSSI), intermittent adductor canal block (iACB), posterior capsule local infiltration analgesia (PC-LIA)
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Taipei Medical University WanFang Hospital
Pain, Postoperative
Postoperative Analgesic Efficacy of Adjuvant Quadratus Lumborum Block in Open Inguinal Hernia Surgery
Evaluation of Postoperative Analgesic Efficacy of Adjuvant Use in Quadratus Lumborum Blocks
- Trial name
- NCT06664164
- Testing
- ANTERİOR QUADRATUS LUMBORUM BLOCK, ANTERİOR QUADRATUS LUMBORUM BLOCK WİTH ADJUVANT
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Maxillofacial Injuries, Maxillofacial Trauma
Superficial Cervical Plexus Block for Orthognathic Surgery
US-guided superficial cervical plexus block (SCPB) may be used for several head and neck surgeries. Local anesthetic is injected under the sternocleidomastoid muscle for SCPB.
- Conditions
- Maxillofacial Injuries, Maxillofacial Trauma, Maxillofacial Abnormalities, Maxillofacial Dysostosis
- Trial name
- NCT04442009
- Testing
- Group SCPB
- Where
- Turkey (Türkiye)
- Sponsor
- Medipol University
Long COVID, Long Covid19
Stellate Ganglion Block to Treat Long COVID 19 Case Series
An assessment of the effectiveness of Stellate Ganglion Block in alleviating symptoms of Long COVID-19.
- Conditions
- Long COVID, Long Covid19, Post-COVID-19 Syndrome, Post Acute COVID-19 Syndrome
- Trial name
- NCT05812209
- Testing
- Stellate Ganglion Block
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Metamorphosis LTD
Physical Disability, Low Back Pain, Recurrent
The Effect of a Developed Perioperative Rehabilitation Pathway Following Lumbar Arthrodesis
To compare the current rehabilitation pathway with the implementation of a newly developed rehabilitation pathway for patients with a single and double level lumbar arthrodesis.
- Conditions
- Physical Disability, Low Back Pain, Recurrent, Surgery
- Trial name
- NCT03427099
- Testing
- Rehabilitation with a biopsychosocial focus, Control group
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Healthy
Modulation of Painful Perception
The objective of the study is to evaluate in healthy volunteers, the influence of empathy on pain perception. It is widely accepted in the clinical management that the feeling of listening to the patients' pain would have a…
- Trial name
- MODOU (NCT02528578)
- Testing
- thermal stimulation delivered by a thermode., functional MRI
- Where
- 2 sites in France
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Healthy
The Effect of Transcranial Direct Current Stimulation of the Primary Motor and Somatosensory Cortex on Pain Thresholds.
The purpose of this study is to investigate the modulatory effect of a novel tDCS configuration on the pain sensitivity in healthy subjects.
- Trial name
- NCT04658485
- Testing
- Active tDCS
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Coronary Artery Disease, Acute Coronary Syndrome
A Registry Study on Genetics and Biomarkers of Acute Coronary Syndrome
This is a national registry study to determine genetics risk factors and serial biomarkers of Acute Coronary Syndrome.
- Conditions
- Coronary Artery Disease, Acute Coronary Syndrome, Acute Myocardial Infarction, Unstable Angina
- Trial name
- ARSGB-ACS (NCT03752515)
- Where
- 6 sites in China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Beijing Institute of Heart, Lung and Blood Vessel Diseases
Migraine, Pain
The Effects of a Long-lasting Infusion of Vasoactive Intestinal Peptide (VIP) in Episodic Migraine Patients
Vasoactive intestinal peptide (VIP) is a peptide of 28 amino acid residues that belongs to the glucagon/secretin superfamily of peptides.
- Conditions
- Migraine, Pain, Neurologic Manifestations, Signs and Symptoms
- Trial name
- NCT04260035
- Testing
- Vasoactive Intestinal Polypeptide (VIP), Sterile saline
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Danish Headache Center
Chronic Pain
2B Active: Outpatient Rehabilitation for Adolescents With Chronic Pain
The purpose of this study is to evaluate whether a multimodal rehabilitation program effectively reduces functional disability in adolescents with chronic musculoskeletal pain, compared to care as usual.
- Trial name
- NCT02181725
- Testing
- Multimodal Rehabilitation Program, Care as Usual
- Where
- 4 sites in Netherlands
- Volunteers
- 60 people
- Sponsor
- Maastricht University Medical Center
Degeneration of Lumbar Intervertebral Disc
Qualitative Pain Measurement at Patients With Degenerative Low Back Pain
The purpose of the study is: to measure sensitization of the nociceptive system at patients with low back pain in order to carry out a necessary surgical procedure to examine a possible association between low back pain and…
- Trial name
- NCT01980576
- Where
- Denmark
- Volunteers
- 1 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Pain, Postoperative, Analgesia
Ultrasound-Guided Bilateral Transversalis Fascia Plane Block With vs Without Dexamethasone for Cesarean Delivery
Cesarean delivery is one of the most frequently performed surgical procedures worldwide, and effective postoperative pain management is essential to facilitate early mobilization, maternal-infant bonding, breastfeeding, and…
- Trial name
- NCT07736989
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Bahçeşehir University
Postoperative Confusion, Postoperative Delirium
Autonomous Nervous System Regulated Paediatric Anaesthesia With Dexmedetomidine or Placebo
The goal of this randomized, double blinded study is to examine in children whether postoperative agitation can be reduced. The main question it aims to answer is Will optimized, monitor guided analgesic treatment and…
- Conditions
- Postoperative Confusion, Postoperative Delirium, Postoperative Pain, Acute, Postoperative Complications
- Trial name
- ANNA (NCT05785689)
- Testing
- Dexmedetomidine
- Where
- Denmark
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Breast Cancer
Musculoskeletal Pain in Postmenopausal, Early Breast Cancer Patients Receiving Aromatase Inhibitor Therapy - A Pilot Study
In 2005, the EBCIG demonstrated the efficacy of tamoxifen in improving overall survival in hormone receptor positive breast cancers.
- Trial name
- AIMS (NCT00653718)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
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