Clinical trials: Painful
Headache
Retrospective Evaluation of Patient Failure to Follow-up at a Community Based Headache Clinic
This is a retrospective review of the records of patients seen at the Kilgo Headache Clinic in Alabama between 7/1/05 and 6/30/07.
- Trial name
- NCT00690989
- Volunteers
- 200 people
- Sponsor
- Kilgo Headache Clinic
Low Back Pain, Stress
Effects of Global Postural Reeducation on Psychophysical Wellbeing in Housewives With Chronic Non-specific LBP.
This study aims to explore the multidimensional impact of Global postural reeducation in a population that is not only physically overburdened but also psychologically strained due to the demands of domestic life.
- Conditions
- Low Back Pain, Stress, Sleep Quality
- Trial name
- NCT07203950
- Testing
- global postural reeducation with conventional therapy, conventional therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Metabolic Syndrome
Serum Concentrations, Physical and Psychological Well-being in Metabolic Syndrome
The purpose of this study was to investigate the serum concentrations, physical and psychological well-being characteristics in patients having chronic musculoskeletal pain with metabolic syndrome, and to compare patients without…
- Trial name
- NCT03338868
- Testing
- Body composition, Physical activity level, Musculoskeletal pain intensity
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ataturk Training and Research Hospital
Diaphragmatic Paralysis, Pain, Chest
Phrenic Nerve Reconstruction for the Treatment of Diaphragmatic Paralysis: Patient Experiences and Reported Outcomes.
This study utilizes a grounded theory methodology to explore patient experiences of phrenic nerve reconstructive surgery as a treatment for diaphragmatic paralysis.
- Conditions
- Diaphragmatic Paralysis, Pain, Chest, Breath Shortness
- Trial name
- NCT06243718
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Advanced Reconstructive Surgery Alliance
Acute Pain, Post Operative Pain
Pharmacogenetic-guided Choice of Post-surgery Analgesics
Pharmacogenomics (PGx) is the study of how genes affect a person's response to drugs. PGx testing for certain genes can help predict the risk of side effects or therapeutic failure from analgesics.
- Trial name
- PRECISE (NCT05548660)
- Testing
- Pharmacogenetic testing, Pharmacist note with genotype-guided analgesic recommendations, Pharmacist detailed note with genotype-guided recommendations per CPIC guidelines
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- University of Pennsylvania
Spine Condition, Low Back Pain
Influence of Flexion Distraction Manipulation on Measures of Performance and Postural Control
This research study will evaluate human performance and postural balance changes during the course of care with flexion distraction manipulation in multiple chiropractic practices.
- Trial name
- NCT06965920
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Keiser University College of Chiropractic Medicine
Kinesiophobia, Pain, Acute
Adaptation of the Motor System to Experimental Pain
This study aims to measure the impact of an experimental pain on electromyography, kinematics of motion and motor cortical excitability.
- Trial name
- KinesioPoint (NCT05396820)
- Testing
- Experimental pain
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universite du Littoral Cote d'Opale
Pain
Effect of the DentalVibe Injection System on Pain During Local Anesthesia Injections in Children
Title: Effect of the DentalVibe injection system on pain during local anesthesia injections in children. Purpose: The purpose of this study is to compare self-reported pain scale measurements using the Wong-Baker FACES pain…
- Trial name
- NCT03374982
- Testing
- DentalVibe
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Nebraska
Back Muscle Spasm, Back Pain
Efficacy and Safety of Tolperisone in Subjects With Pain Due to Acute Back Muscle Spasm
This is a double-blind, randomized, placebo-controlled, multicenter study of the efficacy and safety of tolperisone (a non-opioid) or placebo administered in subjects with pain due to acute back muscle spasm.
- Conditions
- Back Muscle Spasm, Back Pain, Back Strain, Back Spasm Upper
- Trial name
- RESUME-1 (NCT04671082)
- Testing
- Tolperisone Hydrochloride
- Where
- 56 sites in United States
- Volunteers
- 1,004 people
- Sponsor
- Neurana Pharmaceuticals, Inc.
Pain, Postoperative
The Effect of Gabapentin, Ketamine and Dexamethasone on Pain and Opioid Requirements After Hip Surgery
Patients scheduled for primary hip replacement needs postoperative pain treatment, i.e. morphine. Morphine has side-effects: nausea, vomiting, sedation and dizziness.
- Trial name
- NCT00236223
- Testing
- Gabapentin + dexamethasone + ketamine
- Where
- 2 sites in Denmark
- Volunteers
- 48 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Lower Abdominal Surgery
Transversus Abdominis Plane Versus Caudal Block for Pediatrics
The transversus abdominis plane (TAP) block is a relatively simple technique that provides myocutaneous anesthesia that, as part of a multimodal analgesic treatment, may be useful in the prevention and treatment of parietal…
- Trial name
- NCT02398123
- Testing
- Transversus abdominis plane block, Caudal block, Bupivacaine
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Mansoura University
Chronic Low Back Pain
Prevalence of Potential Cytochrome P450 Pharmacokinetic Incident Drug-Drug Interactions Among Chronic Low Back Pain Patients Taking Opioid Analgesics and Associated Economic Outcomes
This study explored the prevalence of DDEs in a chronic pain population with cLBP and associated healthcare utilization and costs using a healthcare claims database.
- Trial name
- NCT01177280
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- NEMA Research, Inc.
Hip or Knee Replacement
'M'-Technique, Guided Imagery, or Standard of Care on Anxiety and Pain Pre- & Post-operatively in Elective Joint Replacement Patients
In the M-TIJRP protocol the investigators will utilize two Integrative Medicine modalities in a randomized, controlled study using either the 'M'-Technique® developed by Jane Buckle, PhD or Diane L.
- Trial name
- M•TIJRP (NCT01874379)
- Testing
- 'M'-Technique®, Guided Imagery, Standard of Care
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Saint Clare's Health System
Colorectal Disorders, Anorectal Disorder
A Multimodal Enhanced Recovery Program in Anorectal Surgery
The goal of this study is to establish whether an opioid-sparing Enhanced Recovery After Surgery (ERAS) program in ambulatory anorectal surgery can be safely introduced at a single tertiary referral center without an increase in…
- Conditions
- Colorectal Disorders, Anorectal Disorder, Patient Satisfaction, Pain, Postoperative
- Trial name
- ARSE (NCT03992079)
- Testing
- ReCOVER Enhanced Recovery Protocol
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Columbia University
Hip Pain, Groin Pain
Categorized PT for Non-arthritic Hip and Groin Pain
There is currently limited literature on a categorized physical therapy protocol for management of hip pain. Only a handful of studies have looked at the treatment of osteoarthritis of the hip with a standardized physical therapy…
- Trial name
- NCT04720846
- Testing
- Matrix-based physical therapy, Standard-of-care physical therapy
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Hospital for Special Surgery, New York
Anesthesia, Local
Conventional Versus Computer-Assisted Dental Anesthesia
The purpose of this clinical trial was to compare two methods of delivering local dental anesthesia in undergraduate dental students: a computer-controlled local anesthetic delivery (CCLAD) system and a conventional dental…
- Trial name
- NCT07731503
- Testing
- Computer-Controlled Local Anesthetic Delivery System, Conventional Aspirating Dental Syringe
- Where
- Mexico
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Montemorelos
Breast Cancer
The Effect of Art Therapy on Pain, Emesis, Anxiety and Quality of Life, Breast Cancer
The research sample consisted of 60 individuals, including the intervention group (n=30) and the control group (n=30), who received treatment at the Oncology Center of Sivas Cumhuriyet University Practice and Research Hospital.
- Trial name
- NCT05666583
- Testing
- Art therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Lomber Disc Herniation
Effectiveness of High Intensity Laser Therapy in Management of Lumbar Disc Herniation
Chronic lumbar radiculopathy is a multifactorial condition typically caused by lumbar disc herniation, where degenerative changes lead to nerve root compression, resulting in radiating pain, sensory disturbances, and motor…
- Trial name
- NCT07550569
- Testing
- Hiltherapy, physiotherapy
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Baskent University
Chronic Pain
Complementary and Integrative Pain Therapies and Functional Restoration (IMPPPORT) Trial)
This study aims to evaluate the benefit of a complementary and integrative health (CIH) pain management program when added to standard rehabilitative care (SC) compared to SC alone prior to an intensive functional restoration…
- Trial name
- IMPPPORT (NCT04656340)
- Testing
- non-medication, non-interventional therapies
- Volunteers
- 210 people
- Sponsor
- Madigan Army Medical Center
Low Back Pain, Mechanical, Degenerative Disc Disease Lumbar
Fusion or Not - a Study on Low Back Pain
Problems from the musculoskeletal system are one of the most common reasons for disability and sick leave. These problems include low back pain. Low back pain affects as many as 8 out of 10 individuals at some point in life.
- Trial name
- NCT06709391
- Testing
- Fusion surgery, Non-fusion surgery
- Where
- 4 sites in Sweden
- Volunteers
- 90 people
- Sponsor
- Uppsala University
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