Clinical trials: Painful
Brain Damage, Hypoxic, Stroke
ESWT for Shoulder Pain in Patients With Brain Damage
This study aimed to investigate the efficacy and safety of extracorporeal shockwave therapy (ESWT) for upper extremity pain related to spasticity in patients with spinal cord injury.
- Conditions
- Brain Damage, Hypoxic, Stroke, Brain Tumor, ICH
- Trial name
- NCT04320108
- Testing
- Extracorporeal shockwave therapy
- Where
- South Korea
- Volunteers
- 6 people
- Sponsor
- Bundang CHA Hospital
Neck Pain, Chronic Neck Pain
Effects of Different Exercise Protocols on Physical and Cognitive Changes in People With Chronic Neck Pain
This study aims to investigate the effects of different exercise approaches on physical status, cognitive functions, brain structures, and blood biomarkers in individuals with chronic neck pain.
- Trial name
- NCT07432425
- Testing
- Aerobic exercise, Strengthening exercise, Posture and strentching exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Hacettepe University
Sinus Disease, Rhinitis
Virtual Reality Induced Analgesia for Nasal Procedures
In-office nasal procedures can cause pain and discomfort to otolaryngology patients. While local anesthesia is the mainstay choice for main management, patients may have allergies or contraindications to the anesthetic agents…
- Conditions
- Sinus Disease, Rhinitis, Turbinate; Hypertrophy Mucous Membrane, Deviated Nasal Septum Acquired
- Trial name
- NCT06812676
- Testing
- Virtual Reality Goggles
- Where
- Saudi Arabia
- Volunteers
- 64 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Forward Head Posture, Neck Pain
Effectiveness of a Telerehabilitation Program Based on Specific Neck Exercises in Patients With Forward Head Posture.
The aim of this study is to compare the effects of a 12-session telerehabilitation program based on Specific Neck Exercises (SNE) with Spinertial to a control group on range of motion, cervical proprioception, and posture in…
- Trial name
- NCT06407089
- Testing
- Spinertial Group
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Universitat Internacional de Catalunya
Pain, Depression
Virtual Reality Effect in Geriatric Individuals
This study aimed to determine the effect of a virtual reality experience on pain, depression and functional adequacy in geriatric individuals living in a nursing home.
- Trial name
- NCT04268589
- Testing
- virtual reality game
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Experimental Pain in Healthy Human Subjects
Intra- and Inter-individual Differences of Pain
Pain is a highly subjective and variable phenomenon. Different persons perceive objectively identical nociceptive stimuli differently.
- Trial name
- NCT05616091
- Testing
- painful stimulation by using a laser device (DEKA Stimul 1340, Calenzano, Italy)
- Where
- Germany
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Postoperative Pain
Effect of Mu-opioid Receptor Genetics on 3 Doses of Spinal Morphine for Postoperative Analgesia After Cesarean Section
HYPOTHESIS: The response to a given dose of morphine given via a spinal anesthetic for cesarean section will be affected by the genetics of the woman's mu-opioid receptor Most women undergoing elective cesarean section (CS)…
- Trial name
- NCT01465191
- Testing
- Morphine
- Where
- 2 sites in United States
- Volunteers
- 169 people
- Sponsor
- Columbia University
Pain
Efficacy of Lumiracoxib in Relieving Moderate to Severe Post-dental Surgery Pain, Compared to Both Placebo and Celecoxib
This study will assess the safety and efficacy of lumiracoxib 400 mg in relieving moderate to severe post-dental surgery pain, compared to both placebo and celecoxib 400 mg.
- Trial name
- NCT00348491
- Testing
- Lumiracoxib
- Where
- United States
- Volunteers
- 364 people
- Sponsor
- Novartis Pharmaceuticals
Procedural Pain
To Explore the Optimal Dose of Dexmedetomidine for Skull Pin Fixation in Intracranial Surgery
Skull pin fixation is commonly used in intracranial surgery, which can increase the surgical field of view. Because skull pin fixation is a very irritating and painful medical treatment, it often results in tachycardia (>150-160…
- Trial name
- NCT06837818
- Testing
- Dexmedetomidine
- Volunteers
- 40 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Postoperative Pain, Psychological Factors
Psychosocial Factors and Postoperative Pain in Aesthetic Breast Surgery
This study investigates the relationship between psychosocial factors, particularly self-esteem and personality traits, and postoperative pain in patients undergoing aesthetic breast surgery.
- Conditions
- Postoperative Pain, Psychological Factors, Breast Surgery, Aesthetic Surgery
- Trial name
- NCT06707818
- Testing
- Preoperative Interventions, Intraoperative Interventions, Postoperative Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- V.K.V. American Hospital, Istanbul
Knee Osteoarthritis
New Options for Treating Knee Osteoarthritis Pain
This study will be a single-site, four-arm, randomized, placebo-controlled clinical trial. Knee osteoarthritis patients (N=164) will be randomized to Reiki, Sham Reiki (placebo control), mindfulness meditation (active control)…
- Trial name
- NCT05541718
- Testing
- Reiki, Mindfulness Meditation
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- University of Utah
Chronic Pain, Cancer
Cancer Chronic Pain Predicted by Emotional and Cognitive Status
The aim of this study is to investigate the predictive dimension of cognitive-emotional status of cancer patients on the chronic pain development 6 months after different cancer treatment protocol (surgery, chemotherapy…
- Trial name
- CanoPEe (NCT02777697)
- Testing
- chronic pain
- Where
- France
- Volunteers
- 89 people
- Sponsor
- University Hospital, Clermont-Ferrand
Knee Osteoarthritis
Pain Compared Between the First and the Second Surgery in Staged BTKA
postoperative pain and analgesic consumption between the first and the second surgery would be compared in patients undergoing staged bilateral total knee arthroplasty (BTKA).
- Trial name
- NCT01457313
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Seoul National University Bundang Hospital
Migraine
An Open Label Extension of a Study Comparing Topiramate and Amitriptyline in Migraine Prevention.
The purpose of this study is to assess the long-term safety and effectiveness of topiramate for the prevention of migraine headaches in adults. Topiramate has been approved to prevent migraine headaches in adults.
- Trial name
- NCT00210860
- Testing
- topiramate
- Volunteers
- 142 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Spondylosis, Osteoarthritis
Medial Branch Radiofrequency Ablation and Lumbar Multifidi
The purpose of this study is to evaluate the effects of lumbar medial branch radiofrequency ablation (RFA) on lumbar multifidi muscle size and clinical spinal stability.
- Trial name
- NCT03744260
- Testing
- Patients undergo ultrasound and lumbar MRI
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Columbia University
Pain, Cardiac Ischemia
Development and Usability Testing of a Progressive WebApp for Women With Heart Disease
The overall goal of this program of research is to develop and systematically evaluate an integrated smartphone and web-based intervention (at heart [formerly called HEARTPA♀N]) to provide evidence-informed symptom triage and…
- Conditions
- Pain, Cardiac Ischemia, Women, Pain, Chronic
- Trial name
- at heart (NCT03800082)
- Testing
- at heart (changed from HEARTPA♀N during usability testing)
- Where
- Canada
- Volunteers
- 98 people
- Sponsor
- University of Toronto
Trigeminal Neuralgia, Pain
Clinical Trial of Hyperbaric Oxygen Treatment in Trigeminal Neuralgia Patients
The purpose of this study is to determine whether the hyperbaric oxygen treatment reduces pain and improve the life quality in trigeminal neuralgia patients.
- Trial name
- NCT00866424
- Testing
- Hyperbaric oxygen, Mock hyperbaric chamber
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xijing Hospital
Angina
Shockwave Treatment for Advanced Angina in Maastricht
There is an increasing number of patients with a coronary anatomy that does not allow additional revascularization procedures, while the patients suffer from angina pectoris at rest or at minimal exercise levels despite optimised…
- Trial name
- SWAAM (NCT01361659)
- Testing
- shockwave treatment
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Maastricht University Medical Center
Pulpotomies Primary Teeth, Anxiety
Dental Game Impact on Kids' Pulpotomy Pain and Anxiety
The aim of this study is to evaluate the effect of a dental simulation game on reducing pain and anxiety during primary teeth pulpotomy.
- Conditions
- Pulpotomies Primary Teeth, Anxiety, Pain
- Trial name
- Electronic (NCT07072559)
- Testing
- dental simulation game, tell show do
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Local Anesthesia
Optimal Lidocaine Buffering to Reduce Injection Pain in Local Anesthesia
The purpose of this study is to determine the optimal amount of lidocaine buffering needed to decrease injection pain when administering local anesthesia.
- Trial name
- NCT02647892
- Testing
- lidocaine, sodium bicarbonate
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Nebraska
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