Clinical trials: Painful
Hip Pain Chronic, Anesthesia
Hip Arthroscopy Pain Control Randomized Control Trial (RCT)
Femoroacetabular impingement is a pathologic process within the hip joint that results from a mechanical discord between the femoral head and neck and the acetabulum that results in chronic hip pain, hip labral tears and early…
- Conditions
- Hip Pain Chronic, Anesthesia, Bupivacaine
- Trial name
- NCT02947178
- Testing
- Fascial iliac regional soft tissue infiltration blockade, Pain Score Survey, Pill Count
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Back Pain, Neck Pain
An App-based Versus a Web-based Self-management Intervention or Usual Care in People With Low Back and/or Neck Pain on a Waiting List for Hospital-based Outpatient Rehabilitation
The purpose of this study is to evaluate the effectiveness of an individually tailored self-management intervention, the selfBACK app, in improving health status in patients on a waiting list for outpatient rehabilitation due to…
- Trial name
- NCT04463043
- Testing
- SelfBACK app, e-Help webpage, Usual care
- Where
- Norway
- Volunteers
- 294 people
- Sponsor
- Norwegian University of Science and Technology
Low Back Pain
Psychological Variables in Physiotherapy Treatment of Low Back Pain: A Comparison of Group and Individual Treatment
The purpose of the study is to determent whether there is a difference between two types of treatments in physiotherapy (individual vs group) for patients with low back pain (LBP), in terms of their sensation of how they have…
- Trial name
- NCT02138071
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- Bait Balev Hospital
Knee Osteoarthritis
Effects of MWM Vs Sustained Mobilization on Knee Osteoarthritis
This article focused on people diagnosed with grade III Knee OA with sample size of 68 patients , who will randomly divided into two groups .
- Trial name
- MWM (NCT07315464)
- Testing
- mulligan moblization, kaltenborn moblization
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Osteoarthritis, Knee
A Phase 1/2A, Single Dose Study Of PF-04383119 In Japanese Patients With Moderate To Severe Pain From Osteoarthritis Of The Knee
To evaluate the safety and tolerability of single IV doses of PF-04383119 in Japanese patients with moderate to severe pain from OA of the knee (Part I).
- Trial name
- NCT00669409
- Testing
- PF-04383119 (tanezumab)
- Where
- 12 sites in Japan
- Volunteers
- 83 people
- Sponsor
- Pfizer
Chronic Low Back Pain, Degenerative Disc Disease
Disc Prosthesis Versus Multidisciplinary Rehabilitation
Surgical methods offered to patients with chronic low back pain are controversial. In addition, new and expensive treatment methods like total disc replacemet (TDR) are a challenge for the health care services.
- Trial name
- NCT00394732
- Testing
- Total Disc Prosthesis, Multidisciplinary rehabilitation program
- Where
- 5 sites in Norway
- Volunteers
- 179 people
- Sponsor
- Ullevaal University Hospital
Postoperative Pain, Regional Anesthesia Morbidity
Rhomboid Intercostal and Subserratus Plane Block
This clinical trial will be conducted at Tanta University Hospitals, General Surgery Hospitals on female patients undergoing radical mastectomy . All the patients will receive general anesthesia.
- Trial name
- NCT04085263
- Testing
- Control group, Rhomboid intercostal and subserratus plane block group
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- Tanta University
Chronic Pain, Persistent Pain
Pleasant Touch Perception in Persistent Pain.
The goal of this observational study is to learn how individuals with chronic pain experience pleasant touch and how often they are exposed to such touch in their daily lives.
- Trial name
- NCT07551687
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Göteborg University
Postoperative Pain, Analgesia
Perioperative Multimodal Analgesia for Supratentorial Craniotomy
This randomized clinical trial aims to evaluate the effectiveness of scalp nerve blocks and dexmedetomidine in reducing opioid use and preventing postoperative delirium in patients undergoing supratentorial brain tumor surgery.
- Conditions
- Postoperative Pain, Analgesia, Supratentorial Brain Tumor
- Trial name
- NCT07441421
- Testing
- Dexmedetomidine, Scalp-Nerve Block
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Tiantan Hospital
Stroke
The Effect of Hand Massage on Pain, Anxiety, and Comfort Levels of Intensive Care Patients
This study titled "Evaluation of the Effect of Hand Massage on Patients' Pain, Anxiety and Comfort Levels" aims to determine the effect of hand massage on patients in intensive care units.
- Trial name
- NCT06808906
- Testing
- Hand Massage Application
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Sakarya University
Chronic Low Back Pain
A Study for Patient With Chronic Low Back Pain
The purpose of this study is to determine if duloxetine reduces the severity of chronic low back pain.
- Trial name
- NCT00767806
- Testing
- Duloxetine
- Where
- 26 sites in United States, Brazil and 5 more
- Volunteers
- 401 people
- Sponsor
- Eli Lilly and Company
Pain, Infection
Safety of Coronectomy vs Excision of Wisdom Teeth
The purpose of this study is to compare the surgical complications and neurosensory disturbance of coronectomy and conventional excision of wisdom teeth with roots in close proximity to inferior alveolar nerve.
- Conditions
- Pain, Infection, Alveolar Nerve Injury
- Trial name
- coronrct (NCT00752284)
- Testing
- Coronectomy, Total Excision
- Where
- China
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Tonsillectomy, Tonsillitis
EXPAREL® for Pain After Tonsillectomy
The purpose of this study is to determine whether liposomal bupivacaine (long acting injectable anesthetic) provides greater post operative pain relief compared to the standard post operative pain regiment for tonsillectomy…
- Conditions
- Tonsillectomy, Tonsillitis, Post-operative Pain
- Trial name
- NCT02444533
- Testing
- Liposomal Bupivacaine
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Pediatric, Radiography
Comparison of Post-operative Pain in Relation to Working Length Assessment by Electronic Apex Locator and Digital Radiography in Permanent Teeth Among Pediatric Patients
This randomized, double-blind clinical trial was conducted at the College of Dentistry, Jouf University, Kingdom of Saudi Arabia, between August 2024 and February 2025.
- Trial name
- NCT07181252
- Testing
- Working length of root
- Where
- Saudi Arabia
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Jouf University
Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
Clinical Evaluation of the Efficacy and Safety of a Medical Device in the Form of Rectal Suppositories (Prospidol®) for the Treatment of Symptoms Associated With Chronic Prostatitis/Chronic Pelvic Pain Syndrome.
The goal of this clinical trial is to evaluate whether a medical device is effective and safe in treating chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) in adult men.
- Trial name
- NCT07685847
- Testing
- Prospidol suppository
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- S&R Farmaceutici S.p.A.
Complex Regional Pain Syndrome
Randomized Controlled Trial of Ketamine Infusion With Continuous Epidural Infusion for Treatment of Complex Regional Pain Syndrome
The purpose of this study is to determine whether epidural and ketamine infusions are effective in the treatment of Complex Regional Pain Syndrome (CRPS).
- Trial name
- NCT02094352
- Testing
- Ketamine Infusion + Epidural Infusion, Control Group + Epidural infusion, Ketamine Booster Infusion
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Lumbar Disc Herniation
SI-6603 (Condoliase) Study for Lumbar Disc Herniation (Discovery 6603 Study)
This study is to evaluate the effectiveness of a single-dose intervertebral disc injection of SI-6603 in subjects with lumbar disc herniation (LDH)
- Trial name
- NCT03607838
- Testing
- SI-6603
- Where
- 67 sites in United States
- Volunteers
- 352 people
- Sponsor
- Seikagaku Corporation
Chronic Pain
Efficacy of Therapy Using Monopolar Dielectric Radiofrequency Signals on the Symptoms of Myofascial Trigger Points in Patients With Chronic Nonspecific Low Back Pain.
A total of 74 people diagnosed with non-specific chronic low back pain of more than 3 months of evolution and who are not currently undergoing any type of treatment will be recruited, with ages between 35 and 65 years.
- Trial name
- NCT05471258
- Testing
- Experimental: monopolar dielectric diathermy
- Where
- Spain
- Volunteers
- 74 people
- Sponsor
- Universidad de Almeria
Low Back Pain, Recurrent, Chronic Low Back Pain (CLBP)
Magnetic Resonance Elastography Of Chronic Low Back Pain Before And After Therapy
The purpose of this study is to quantify Magnetic Resonance Elastography (MRE)-derived mechanical property biomarkers of the lumbar paraspinal musculature and associated myofascial tissue regions before and after the intervention.
- Trial name
- NCT07712458
- Testing
- EMMA (Expert Manipulative Massage Automation)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Mayo Clinic
Metastatic Cancer, Pain
Percutaneous Cryoablation in Treating Patients With Painful Bone Metastases
RATIONALE: Percutaneous cryoablation may help relieve pain caused by bone metastases. PURPOSE: This clinical trial is studying the side effects and how well percutaneous cryoablation works in treating patients with painful bone…
- Conditions
- Metastatic Cancer, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00608855
- Testing
- questionnaire administration, cryosurgery, pain therapy
- Where
- 10 sites in United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
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