Clinical trials: Painful
Stage II and III Breast Cancer
Melatonin as Adjuvant Therapy in Breast Cancer Patients
The study evaluate the effect of melatonin in improving quality of life and reducing post operative pain and chemotherapy-induced toxicity in breast cancer patients.
- Trial name
- MIQOL-B (NCT01557478)
- Testing
- Melatonin
- Where
- 2 sites in Thailand
- Volunteers
- 166 people
- Sponsor
- Khon Kaen University
Postoperative Pain
Effect of Dexamethasone and Epinephrine on the Duration of Sciatic Nerve Blocks With Ropivacaine
The aim of the present study is to test that adding dexamethasone or epinephrine significantly prolongs the duration of sciatic nerve blocks with ropivacaine and that the magnitude of the effect differs among dexamethasone and…
- Trial name
- NCT02104778
- Testing
- Dexamethasone, Epinephrine
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Yeungnam University College of Medicine
Surgery, Incisional Hernia
Suture Techniques to Reduce the Incidence of Incisional Hernia: LTFU STITCH Trial
Rationale: Incisional hernias (IH) are a frequent complication after abdominal surgery. Prevalence of an IH varies depending on the previous abdominal procedure but could be as high as 70% in high-risk patients after open…
- Conditions
- Surgery, Incisional Hernia, Wound Infection, Fascial Dehiscence
- Trial name
- LTFU-STITCH (NCT06066385)
- Testing
- Small bites technique, Conventional large bites closure
- Where
- 9 sites in Netherlands
- Volunteers
- 560 people
- Sponsor
- Erasmus Medical Center
Piriformis Syndrome
Comparative Effects of Stecco-fascial Manipulation and Rolfing Structural Integration in Patients With Piriformis Syndrome
This study aims to compare the effectiveness of Stecco Fascial Manipulation and Rolfing Structural Integration in treating Piriformis syndrome, focusing on special outcomes like pain severity and functional outcomes.
- Trial name
- Piriformis (NCT07322185)
- Testing
- Experimental: GROUP A ( Stecco fascial Manipulation), Experimental: GROUP B (Rolfing Structural Integration)
- Where
- 3 sites in Pakistan
- Volunteers
- 42 people
- Sponsor
- Danyal Ahmad
Sacroiliac Joint Pain
Comparison Between Traditional Bipolar Radiofrequency and Cooled Radiofrequency in Sacroiliac Joint Pain Patients
Sacroiliac joint pain is contributor to chronic low back pain, accounting for 15-30% of cases. It is a synovial and syndesmotic articulation plays a role in load transfer between spine and lower extremities.
- Trial name
- NCT07749599
- Testing
- Traditional bipolar radiofrequency, Cooled radiofrequency
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Acute Pain
IV Acetaminophen as Adjuvant Analgesic to Hydromorphone - Emergency Department Patients
The goal of this randomized clinical trial is to compare the analgesic efficacy and side effect profile of IV acetaminophen as an analgesic adjunctive medication to IV hydromorphone for the treatment of acute pain experienced by…
- Trial name
- NCT03553498
- Testing
- IV acetaminophen, hydromorphone
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Albert Einstein College of Medicine
Pain Management
Evaluation of the Efficacy and Onset of Action of a Topical Anesthetic Marker
The goal of this clinical trial is to to demonstrate the efficacy of a topical anesthetic in reducing pain during the performance of a painful test on the participant's arm.
- Trial name
- NCT07273916
- Testing
- Cutaneous marker (Transcutol P+ 20%, Tetracaine 7%, Lidocaine 23%, and dye q.s.),
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hexsel Dermatology Clinic
Cervical Dystonia
Effect of Osteopathic Manipulative Medicine on Motor Function and Quality of Life in Cervical Dystonia
The purpose of the proposed research is to determine if Osteopathic manipulative medicine (OMM) used alone or in combination with the standard treatment of botulinum toxin intramuscular injections improves motor function and…
- Trial name
- NCT02420106
- Testing
- Osteopathic Manipulative Medicine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- New York Institute of Technology
Anxiety Acute, Chronic Pain
Canine-Assisted ANxiety Reduction IN Emergency Care IV
Prior literature demonstrates that human stress can be reduced with exposure to animals. This study challenges current dogma by introducing a widely available, low cost method of dog therapy to reduce patient and provider stress.
- Trial name
- CANINE IV (NCT04287452)
- Testing
- Control, Dog Therapy
- Where
- United States
- Sponsor
- Indiana University
This Study Aims to Examine the Effect of a Wearable Posture Corrector Device on Back Pain Body Image and Postural Awareness in Young Adult Women
Young Adult Women and Wearable Posture Corrector Device
To improve posture, methods such as strengthening specific muscles or focusing on body alignment are commonly used. In addition to elastic posture correctors, electronic posture reminders can also be utilized.
- Trial name
- NCT07816952
- Testing
- Wearable posture corrector device
- Volunteers
- 90 people
- Sponsor
- Pamukkale University
Effect of Reflexology on Premenstrual Syndrome Symptoms
The Effect of Reflexology on Premenstrual Syndrome Symptoms, Pain and Quality of Life
This study was planned as a randomized controlled experimental study to examine the effect of reflexology on premenstrual syndrome symptoms, pain and quality of life in women with premenstrual syndrome between January 2025 and…
- Trial name
- NCT06961552
- Testing
- reflexology masaj group
- Volunteers
- 70 people
- Sponsor
- Saglik Bilimleri Universitesi
Healthy, Neck Pain
The Effect of Experimental Neck Pain in Healthy Participants
This study investigates if/how an experimentally applied muscle pain/soreness, lasting for some days may affect brain activity, balance, movement patterns, muscle function and pain sensitivity in a healthy population
- Trial name
- NCT03848247
- Testing
- Injection of Isotonic saline, Injection of NGF
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Chronic Pain
Feasibility Study of an Online Self-management Program for Chronic Non-cancer Pain
Based on a mixed-methods design, the objective of this trial is to assess the feasibility and acceptability of the "Agir pour moi" program, an 8-week online self-management program for chronic non-cancer pain (CNCP).
- Trial name
- NCT05319652
- Testing
- Pain self-management program
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- CHU de Quebec-Universite Laval
Opioid Use, Pain, Postoperative
Pain in Breast Surgery Intervention
This study will be a randomized control trial providing an educational component to study participants and a pre-operative and post-operative survey with a goal to show an improvement in pain control, decrease in narcotic use…
- Trial name
- NCT04058938
- Testing
- Educational handout instrument, Control
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Pain, Postoperative
Ketorolac Applied by Continuous IV Infusion for Treatment of Moderately Severe Postoperative Pain Following Bunionectomy
This clinical study is a randomized, double-blind, double-dummy, parallel group, multi-center, active and placebo-controlled trial evaluating the analgesic efficacy and safety of NTM-001 in subjects with moderately severe…
- Trial name
- NCT05324358
- Testing
- Ketorolac Tromethamine, Morphine Sulfate
- Where
- 10 sites in United States
- Volunteers
- 341 people
- Sponsor
- Neumentum, Inc.
Hepatic Resection, Acute Pain
Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic Resection
To determine whether the addition of erector spinae plane (ESP) catheters to existing multimodal analgesic regimen with intrathecal morphine provides superior postoperative analgesia in patients undergoing hepatic resection…
- Conditions
- Hepatic Resection, Acute Pain, Anesthesia, Anesthesia, Local
- Trial name
- NCT04849455
- Testing
- 0.2% ropivacaine local anesthetic continuous erector spinae plane block, 0.2% ropivacaine local anesthetic superficially taped continuous erector spinae plane block, Spinal Morphine
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Diego
Cesarean Delivery
Postoperative Cesarean Delivery Pain Relief; Diclofenac Versus Bupivacaine
This randomized controlled trial, compared postoperative pain score in patient undergoing cesarean delivery between bupivacaine peritoneal and subcutaneous infiltration and diclofenac intramuscular injection
- Trial name
- NCT03039426
- Testing
- Bupivacaine, Diclofenac
- Where
- 2 sites in Thailand
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Neck Pain, Pain, Neck
Evaluation of the Effect of the OMT Exercises Education for Pain in Participants With Cervical Pain
The purpose of this randomized pragmatic clinical trial is to assess the effectiveness of the association of the osteopathic manipulative treatment in individuals with chronic non-specific neck pain who receive a exercice program…
- Trial name
- NCT03085355
- Testing
- Exercises and PNE, Osteopathic manipulative treatment
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Instituto Brasileiro de Osteopatia
Thoracoabdominal Wall Pain, Secondary to Parietal Pleura or Parietal Peritoneum Disease
A Study of Stereotactic Radiosurgery (SRS) to Treat Pain in the Chest and/or Stomach Wall
The researchers are doing this study to find out whether stereotactic radiosurgery (SRS) is a safe, practical (feasible), and effective treatment for people with chronic TAWP.
- Trial name
- NCT05985148
- Testing
- Single-fraction stereotactic radiosurgery (SRS)
- Where
- 7 sites in United States
- Volunteers
- 18 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cancer, Breakthrough Cancer Pain
Inhaled Cannabinoids Versus Immediate-release Oral Opioids for the Management of Breakthrough Cancer Pain
Breakthrough cancer pain (BTcP) is a rapid onset, high intensity and short duration pain episode, which takes place within stable background pain control.
- Trial name
- REBORN (NCT03564548)
- Testing
- PPP001, Morphine sulfate or Hydromorphone or Oxycodone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Tetra Bio-Pharma
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