Clinical trials: Painful
Low Back Pain
Photobiomodulation Therapy on Inflammatory Mediators on Low Back Pain
Low back pain (LBP) is ranked as one of the most prevalent health conditions. It is likely that some inflammatory mediators could be associated with pain and disability in these patients.
- Trial name
- NCT03859505
- Testing
- Active PBMT
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- Universidade Cidade de Sao Paulo
Low Back Pain
Evaluation of the Japet.W+ Medical Device for Low Back Pain Management
The JAPET.W+ medical device is a new dynamic distraction support system. It could be considered as a new solution in the therapeutic arsenal for managing common low back pain.
- Trial name
- EXODOMICILE (NCT07195422)
- Testing
- Japet.W+, Control (Standard treatment)
- Where
- 2 sites in France
- Volunteers
- 102 people
- Sponsor
- Japet Medical Devices
Symptomatic Apical Periodontitis
Comparison of Postoperative Pain After Double Antibiotic Paste vs Calcium Hydroxide in Teeth With Symptomatic Apical Periodontitis
This randomized controlled trial aims to compare the mean postoperative pain after using double antibiotic paste (DAP) versus calcium hydroxide (CH) as an intracanal medicament in teeth with symptomatic apical periodontitis.
- Trial name
- NCT07867951
- Testing
- Calcium Hydroxide (Ca(OH)2), Double Antibiotic Paste
- Where
- Pakistan
- Volunteers
- 662 people
- Sponsor
- College of Physicians and Surgeons Pakistan
Acute Pain
Psychosocial Support for Acute Hospital Pain and Distress
The purpose of this randomized study is to determine the impact of three different types of psychosocial support delivered by social workers to patients reporting uncontrolled pain during a hospital stay.
- Trial name
- NCT02590029
- Testing
- Mindfulness, Suggestion, Psychoeducation
- Where
- United States
- Volunteers
- 244 people
- Sponsor
- University of Utah
Labor Pain, Nociceptive Pain
Nociception Level Index (NOL Index) for Obstetrical Pain Assessment Under Epidural Analgesia.
Pain has been defined by the International Association for the Study of Pain (IASP) as "an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage".
- Conditions
- Labor Pain, Nociceptive Pain, Epidural Analgesia, NOL Index
- Trial name
- NCT05898737
- Testing
- NOL-Index
- Where
- Belgium
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Post Operative Pain, Inguinal Hernia
Comparison of Two Different Analgesic Regional Block Techniques in Pediatric Patients Undergoing a Hernia Repair
Lower abdominal operations; especially inguinal hernia repairs are one of the most frequently performed operations in the daily practice of pediatric surgeries.Regional anesthesia techniques are frequently and effectively used…
- Trial name
- NCT05896072
- Testing
- Erector Spinae Plane Block, Caudal Block
- Where
- 7 sites in Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Abant Izzet Baysal University
Pain
Safety of Twice Daily Oxycodone Hydrochloride Controlled-release Tablets in Children With Moderate to Severe Malignant and/ or Nonmalignant Pain Requiring Opioids
The purpose of this study is to characterize the safety of oxycodone hydrochloride (HCl) controlled-release (CR) tablets in opioid tolerant pediatric patients aged 6 to 16 years, inclusive, with moderate to severe malignant…
- Trial name
- NCT01192295
- Testing
- Oxycodone HCl controlled-release tablets
- Where
- 47 sites in United States, Greece and 6 more
- Volunteers
- 155 people
- Sponsor
- Purdue Pharma LP
Metatarsalgia, Treatment
Orthopaedic Treatment in Propulsive Metatarsalgia
The goal of this clinical trial is to compare the effectiveness of two conservative orthopedic treatments in propulsive metatarsalgia.
- Conditions
- Metatarsalgia, Treatment, Foot, Foot Diseases
- Trial name
- NCT05713175
- Testing
- EVA plantar orthosis, Polypropylene plantar orthosis, Fixtoe device
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Universidad Complutense de Madrid
Hemodialysis, Arteriovenous Fistula Cannulation
Breathing Exercises for Pain and Anxiety During Arteriovenous Fistula Cannulation
This study aims to evaluate the effects of guided 4-7-8 and diaphragmatic breathing exercises performed during arteriovenous fistula cannulation on pain, anxiety, and comfort levels in patients undergoing hemodialysis treatment.
- Conditions
- Hemodialysis, Arteriovenous Fistula Cannulation, Breathing Exercises, Pain
- Trial name
- NCT07427875
- Testing
- Guided 4-7-8 Breathing Exercise, Guided Diaphragmatic Breathing Exercise, routine care
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Emine Kaplan Serin
Headache
Lokal Cold Application in Nitroglycerin-Induced Headache (NIH)
The study was planned to evaluate the effect of local cold application on headache severity in individuals who received intravenous nitroglycerin treatment, which mostly causes headache due to its vasoditator effect.
- Trial name
- NCT04707586
- Testing
- Cold Application
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Yasemin Kalkan Uğurlu
Music Therapy, Anxiety
Receptive Music Interventions During Intradermal Testing in Children
The study summary and design were to assess procedural anxiety and stress in parents and pain perception in children during intradermal testing.
- Conditions
- Music Therapy, Anxiety, Pain Management, Skin Tests
- Trial name
- NCT07013669
- Testing
- Receptive Music Therapy - Solfeggio Frequencies, Receptive Music Therapy - Traditional Turkish Music
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Hilal Gungor
Urine Specimen Collection
The Effect of Non-invasive Bladder Stimulation Technique on Collecting Urine Specimen in Infants Under One Year Old
Urinary tract infection (UTI) is common in early childhood. The American Academy of Pediatrics accepts suprapubic aspiration and bladder catheterization as the gold standard for the diagnosis of UTI.
- Trial name
- NCT05394454
- Testing
- Bladder stimulation technique
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Istanbul University - Cerrahpasa
Musculoskeletal Pain
Assessment of the Effects of Extensive Somatosensory Training on Pain Processing
Persistent pain may lead to several alterations in the brain activity and sensory perception (i.e. pain). Around 80% of professional musicians experience prolonged episodes of musculoskeletal pain throughout their careers, a…
- Trial name
- NCT04457466
- Testing
- Nerve Growth Factor
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Pain, Postoperative, Osteoarthritis
Pain Treatment After Total Knee Replacement - Continuous Epidural Versus Intravenous Patient Controlled Analgesia With Morphine
The study purpose is to compare the effectiveness of different methods for post-operative pain treatment after total knee replacement.
- Trial name
- NCT00270322
- Testing
- Marcaine 0.166% + Fentanyl 3.33 mcg/ml, Morphine sulphate
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rambam Health Care Campus
Hemophilia Arthropathy
Pain in Patients With Congenital Coagulopathies
Introduction. The development of joint hemorrhages in patients with congenital coagulopathies favor the development of an intra-articular, degenerative and progressive lesion (hemophilic arthropathy).
- Trial name
- He-PainSit (NCT03499522)
- Testing
- Observational group
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Real Fundación Victoria Eugenia
Angina Pectoris, Microvascular Angina
Angina in Non Coronary Artery Disease
Many patients undergoing coronary angiography are found to have no significant coronary artery disease (CAD) despite angina equivalent symptoms and/or electrocardiographic abnormalities suggestive of myocardial ischemia.
- Conditions
- Angina Pectoris, Microvascular Angina, Angina Pectoris, Variant
- Trial name
- HeartQuest (NCT01318629)
- Where
- Switzerland
- Volunteers
- 718 people
- Sponsor
- Luzerner Kantonsspital
Postoperative Pain Management, Penile Surgery-Related Pain
Anatomical Measurements of Pudendal Nerve Block in Children
This prospective observational study aims to investigate the relationship between anatomical parameters-specifically the distance from the anus to the needle insertion point and the depth required to reach the pudendal…
- Trial name
- NCT07348029
- Testing
- Neurostimulation-Guided Pudendal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Low Back Pain
Variable Approaches of Intradiscal O3-O2 Injection
Cost Intradiscal injection of ozone-oxygen mixture (O3-O2) which offers a rapid onset amelioration of symptoms, with a sustained duration pain relief in low back pain. Does change of injection approach make a difference?
- Trial name
- NCT03038529
- Testing
- Classic postrolateral extraarticular percutaneous approach for O3 injection, Postrolateral transforaminal approach (Yess approach ) for O3 injection
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
CRPS
Prospective, Randomized Controlled Trial on Perioperative Pregabalin to Reduce Late-onset CRPS After TKA
The Department of Anesthesiology is conducting a clinical trial to evaluate if pregabalin given prior to and for several days after Total Knee Arthroplasty (TKA) will reduce the prevalence of Complex Regional Pain Syndrome (CRPS)…
- Trial name
- PregTKA (NCT00558753)
- Testing
- pregabalin
- Volunteers
- 240 people
- Sponsor
- Rush University Medical Center
Patient With Neuropathic Pain
Impact of Oral Magnesium on Neuropathic Pain
Use lay language. The aim of this study is to evaluate on pain scores (neuropathic pain questionnaire and pain numeric scale) and on quality of life, the effect of oral magnesium intake on patients with neuropathic pain comparing…
- Trial name
- NCT01121653
- Testing
- Magnogene ® (magnesium)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Clermont-Ferrand
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