Clinical trials: Painful Bladder Syndrome (PBS)
Interstitial Cystitis, Bladder Pain Syndrome
Identifying Genetic Causes of IC/BPS
Interstitial cystitis (IC), also called Bladder Pain syndrome (BPS) is a common condition with no known cause or cure. Twin studies and family accounts have suggested that the condition may be genetic or passed down (inherited)…
- Trial name
- NCT00389142
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Boston Children's Hospital
Bladder Diseases, Interstitial Cystitis
Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS)
This is a randomized clinical trial study to test the efficacy and safety of amitriptyline in the treatment of patients newly diagnosed with painful bladder syndrome (PBS).
- Trial name
- IC01 (NCT00124306)
- Testing
- Amitriptyline
- Where
- 10 sites in United States, Canada
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Bladder Pain Syndrome, Painful Bladder Syndrome
Aerobic Exercise and Connective Tissue Massage in Painful Bladder Syndrome
The goal of this clinical trial is to learn if aerobic exercise training and connective tissue massage, in addition to patient education, can help treat women with bladder pain syndrome.
- Conditions
- Bladder Pain Syndrome, Painful Bladder Syndrome, Painful Bladder Syndrome (PBS), Interstitial Cystitis and Bladder Pain Syndrome
- Trial name
- NCT07839689
- Testing
- Patient Education, Aerobic Exercise Training, Connective Tissue Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Hacettepe University
Interstitial Cystitis, Mindfulness
Mindfulness-Based Therapy for Interstitial Cystitis/Bladder Pain Syndrome
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a poorly understood disease with unreliable treatments. Although it is not known what causes it for certain, we do know that life stressors may make the disease worse or…
- Conditions
- Interstitial Cystitis, Mindfulness, Complementary Medicine, Painful Bladder Syndrome
- Trial name
- NCT02457182
- Testing
- Mindfulness-based Stress Reduction (MBSR), Usual medical therapy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Painful Bladder Syndrome, Interstitial Cystitis
Study of URG101 in Painful Bladder Syndrome and Interstitial Cystitis
A double-blind, placebo-controlled study to evaluate changes in pain, urgency and urinary frequency following administration of URG101 compared to placebo.
- Conditions
- Painful Bladder Syndrome, Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT00517868
- Testing
- URG101
- Where
- 6 sites in United States
- Volunteers
- 28 people
- Sponsor
- Urigen
Cystitis, Interstitial
Safety and Efficacy of AGN 203818 for Pain Associated With Painful Bladder Syndrome/Interstitial Cystitis
This study will explore the safety and effectiveness of different doses of AGN 203818 in treating the pain associated with painful bladder syndrome/interstitial cystitis
- Trial name
- NCT00380783
- Testing
- AGN 203818
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Allergan
Cystitis, Interstitial, Dysmenorrhea
Chronic Pain Risk Associated With Menstrual Period Pain
The purpose of this study is to determine if some women with dysmenorrhea (painful periods) are at higher future risk of developing chronic pelvic pain (CPP) and if oral contraceptives (OC) can be used to reverse this chronic…
- Conditions
- Cystitis, Interstitial, Dysmenorrhea, Migraine Disorders, Pelvic Pain
- Trial name
- CRAMPP (NCT02214550)
- Testing
- cyclic microgestin 1/20, continuous microgestin 1/20
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Chronic Pelvic Pain Syndrome, Bladder Pain Syndrome
Chronic Bladder Pain Syndrome in Women: Can Doxycycline Help? A Prospective Study
Chronic bladder pain syndrome is a chronic disabling disorder characterized by chronic pelvic pain, pressure or discomfort perceived to be related to the urinary bladder accompanied by at least one other urinary symptom such as…
- Trial name
- NCT01879930
- Testing
- doxycycline
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Interstitial Cystitis
A Pilot Clinical Investigation of the Efficacy and Safety of Uracyst® Versus Placebo in Patients With Interstitial Cystitis/Painful Bladder Syndrome.
This is a pilot clinical investigation. Patients who meet the eligibility criteria and provide signed informed consent will be randomized to receive either an active product (Uracyst®) or placebo intravesically via a bladder…
- Trial name
- NCT00527917
- Testing
- Uracyst
- Where
- 13 sites in Canada
- Volunteers
- 65 people
- Sponsor
- Watson Pharmaceuticals
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Interstitial Cystitis/Painful Bladder Syndrome
Retrospective Results of Micronized Adipose Tissue in Patients With Interstitial Cystitis
Interstitial cystitis (IC) is a chronic, urological condition characterized by bladder pain, and persistent urinary symptoms. Its complex pathophysiology involves autoimmune mechanisms, urothelial barrier dysfunctions…
- Trial name
- IC_&_MAT_MSCs (NCT07104981)
- Testing
- Mesenchymal Stem Cell Transplantation
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Roma La Sapienza
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma
Evaluation of Radiobiological Effects in Skin Toxicities Head and Neck Cancer Patients With PBS Proton Therapy
This purpose of this study is to examine skin reactions (called radiation dermatitis) that occur during pencil beam scanning (PBS) proton therapy.
- Conditions
- Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma, Head and Neck Carcinoma
- Trial name
- NCT06183268
- Testing
- Spot Delete
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Covenant Health Cancer Center
Interstitial Cystitis, Bladder Pain Syndrome
Efficacy and Safety of AQX-1125 in IC/BPS
The primary objective of this study is to evaluate the effect of 6 weeks of treatment with once daily administration of AQX-1125 compared to placebo on average daily pain in subjects with interstitial cystitis/bladder pain…
- Trial name
- LEADERSHIP (NCT01882543)
- Testing
- AQX-1125
- Where
- 29 sites in United States, Canada
- Volunteers
- 69 people
- Sponsor
- Aquinox Pharmaceuticals (Canada) Inc.
Interstitial Cystitis
Low Energy Shock Wave for the Treatment of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)
To investigate the efficacy and safety of LESW on participants with IC/BPS
- Trial name
- NCT03619486
- Testing
- Low energy shock wave
- Where
- Taiwan
- Volunteers
- 49 people
- Sponsor
- Chang Gung Memorial Hospital
Interstitial Cystitis, Painful Bladder Syndrome
Bladder Capacity as Objective Measure of Intravesical Treatment of Newly Diagnosed IC
A comparative study of subjective outcomes following intravesical treatment of interstitial cystitis (IC) is lacking in the literature.
- Trial name
- NCT05223244
- Testing
- bupivacaine, triamcinolone, and heparin (BTH), dimethyl sulfoxide (DMSO)
- Volunteers
- 83 people
- Sponsor
- Endeavor Health
Interstitial Cystitis/Bladder Pain Syndrome, Underactive Bladder
SNM vs. HBOT for Refractory IC/BPS
This study is for people with long-term bladder pain and urinary problems (known as Interstitial Cystitis/Bladder Pain Syndrome or IC/BPS) that have not improved with other treatments.
- Trial name
- NCT07091266
- Testing
- Sacral Neuromodulation (SNM), Hyperbaric Oxygen Therapy (HBOT)
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Shiyan City Renmin Hospital
Interstitial Cystitis
A Study to Test if Fremanezumab Reduces Pain in Patients With Interstitial Cystitis-Bladder Pain Syndrome
The primary objective of the study is to evaluate the efficacy of fremanezumab in reducing pain in patients with interstitial cystitis-bladder pain syndrome (IC-BPS).
- Trial name
- NCT04447729
- Testing
- fremanezumab
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Interstitial Cystitis Bladder Pain Syndromes
PTNS Versus Sham Efficacy in Treatment of BPS
This is a prospective, single center, double-blind, randomized, controlled trial comparing the efficacy of percutaneous tibial nerve stimulation to sham in the treatment of Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC)…
- Trial name
- NCT02747420
- Testing
- NURO TM
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Interstitial Cystitis, Bladder Pain Syndrome
Platelet Enriched Plasma for Treatment of Interstitial Cystitis
A prospective randomized trial will be conducted aiming at evaluation the efficacy and safety of platelet enriched plasma for management of bladder pain syndrome .
- Conditions
- Interstitial Cystitis, Bladder Pain Syndrome, Platelet Enriched Plasma
- Trial name
- NCT04118946
- Testing
- platelet enriched plasma
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Mansoura University
Urinary Frequency/Urgency, Bladder Irritable
Mirabegron for the Treatment of Pain Motivated Urinary Frequency and Urgency in Women
The specific purpose of this study is to provide objective data in prospective open label design (n=40) to support the use of Mirabegron as a treatment for pain related urinary frequency and urgency.
- Conditions
- Urinary Frequency/Urgency, Bladder Irritable, Bladder Pain Syndrome
- Trial name
- NCT02981459
- Testing
- Mirabegron
- Where
- United States
- Sponsor
- State University of New York at Buffalo