Clinical trials: Painful Peripheral Neuropathy
Spinal Nerve Root Disorder Nos
Concurrent Treatment for Patients With Cervical Radiculopathy
This study evaluates the effectiveness of two treatment interventions in patients with cervical radiculopathy. One group will receive a concurrent approach using traction and neuromobilizations.
- Trial name
- NCT03636009
- Testing
- concurrent traction and neuromobilization technique, sequential traction and neuromobilization technique, active exercise program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Indianapolis
Herpes Zoster
Burden of Herpes Zoster and Post-herpetic Neuralgia Among People ≥ 50 Years Old in France
The purpose of this study is to assess the burden of Herpes zoster (HZ) and post-herpetic neuralgia (PHN) among people ≥ 50 years old in France, in terms of healthcare resources used, medical direct and indirect costs, as well as…
- Trial name
- NCT02487472
- Testing
- Data collection
- Volunteers
- 106 people
- Sponsor
- GlaxoSmithKline
Neuropathic Pain, Pain
Optimized Programming in Spinal Cord Stimulation (SCS) System
The objective of this study is to evaluate extent, location, and perception of paresthesia as a function of anode/cathode configuration.
- Trial name
- OP (NCT00871819)
- Testing
- Precision Spinal Cord Stimulation (SCS)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Stroke
Effects of Task-Based Mirror Therapy for Post-stroke Shoulder-Hand Syndrome
The study aims to determine the effects of task-based mirror therapy on edema, pain and upper limb motor function with shoulder-hand syndrome in post stroke patients.
- Trial name
- NCT07428811
- Testing
- Task based mirror therapy, Conventional exercises
- Where
- 2 sites in Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Neuropathic Pain
Spinal Cord Stimulation and Physiotherapy for Treatment of Neuropathic Pain
The study evaluates the combined effect of optimized pharmacological treatment, spinal cord stimulation and physiotherapy on pain relief, health-related quality of life and physical function in patients with neuropathic pain.
- Trial name
- SCS-PHYSIO (NCT03740763)
- Testing
- Spinal Cord Stimulation (SCS), Physiotherapy
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Göteborg University
Diabete Type 2
Normast3 for Adults With Diabetic Polyneuropathy
The goal of this clinical trial is to find out if a new supplement called Normast® 3 can help reduce nerve pain and improve nerve function in adults with diabetic polyneuropathy (DPN).
- Trial name
- NCT07689214
- Testing
- Normast® 3 - a food for special medical purposes (FSMP) containing co-micronized palmitoylethanolamide (PEA) with rutin and hydroxytyrosol. It is designed to support the management of diabetic polyneu
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Roma La Sapienza
Lumbar Radiculopathy
Effects of Neural Flossing and PNF on Lumbar Radiculopathy
the goal of this clinical trial is to determine the effects of neural flossing with and without proprioceptive neuromuscular facilitation on pain, range of motion and disability in patients with lumbar radiculopathy.
- Trial name
- NCT05922228
- Testing
- neural flossing with proprioceptive neuromuscular facilitation, Neural flossing without proprioceptive neuromuscular facilitation
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Diabetic Neuropathies, Polyneuropathies
Neuropathic Pain Management
This is a prospective, randomized, double blind, comparative, experimental controlled Phase 3 clinical trial to assess the efficacy, safety and superiority of F0343 (gabapentin combined with B vitamins) compared to gabapentin…
- Trial name
- M-F0434 (NCT01263132)
- Testing
- F0434, Gabapentin
- Where
- Mexico
- Volunteers
- 104 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Postherpetic Neuralgia
Efficacy and Safety of LX9211 in Participants With Postherpetic Neuralgia
Evaluation of the efficacy of LX9211 compared to placebo in reducing pain related to postherpetic neuralgia over an 11 week assessment period.
- Trial name
- RELIEF-PHN1 (NCT04662281)
- Testing
- LX9211
- Where
- 32 sites in United States, Czechia and 1 more
- Volunteers
- 79 people
- Sponsor
- Lexicon Pharmaceuticals
Cluneal Syndrome
Proximal Versus Distal Superior Cluneal Nerve Block in Entrapment Neuropathy
Superior cluneal nerve (SCN) entrapment is an underdiagnosed cause of chronic low back and gluteal pain. Although diagnostic nerve block is considered the gold standard for confirming SCN entrapment, there is no consensus…
- Trial name
- NCT07372430
- Testing
- Ultrasound-guided distal superior cluneal nerve injection, Ultrasound-guided proximal superior cluneal nerve injection
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Neuropathic Pain
Electroencephalography Based Neurofeedback in Chronic Neuropathic Pain
Chronic neuropathic pain is a global health concern, affecting millions of patients worldwide. It is often extremely debilitating and poses a diagnostic and therapeutic challenge.
- Trial name
- NCT01560039
- Testing
- TMS, Neurofeedback
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Neuropathic Pain
Injection Therapy for Neuropathic Pain
Shoulder, neck, back and temporal pain and herpes zoster pain are neuropathic pain. Preliminary clinical studies have confirmed that injection of freshly prepared HA35 can relieve neuropathic pain.
- Trial name
- NCT05809700
- Testing
- Freshly manufactured 35 kDa hyaluronan fragment
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Dove Medical Press Ltd
Complex Regional Pain Syndrome I of Upper Limb, Pain
THE EFFECTS OF FUNCTIONAL ELECTRICAL STIMULATION-ASSISTED BICYCLE ERGOMETRY IN PATIENTS DIAGNOSED WITH COMPLEX REGIONAL PAIN SYNDROME.(CRPS)
The goal of this clinical study is to evaluate the effectiveness of functional electrical stimulation (FES)-assisted cycling in patients with post-stroke Complex Regional Pain Syndrome (CRPS) Type 1.
- Trial name
- CRPS (NCT07570199)
- Testing
- Functional Electrical Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Zeynep Nur Köseoğlu
Stroke, Ischemic, Coronary Artery Disease
BuqitongluO Granule for Qi Deficiency and Blood Stasis Syndrome
The main purpose of this trial is to evaluate the efficacy and safety of Buqitongluo Granule in treating qi deficiency and blood stasis syndrome, and explore the effect of the improvement of qi deficiency and blood stasis…
- Conditions
- Stroke, Ischemic, Coronary Artery Disease, Angina Pectoris, Stable, Diabetic Peripheral Neuropathy
- Trial name
- BOSS (NCT04408261)
- Testing
- Buqitongluo Granule, Standard care
- Where
- China
- Volunteers
- 432 people
- Sponsor
- Dongzhimen Hospital, Beijing
Postherpetic Neuralgia, Neuropathic Pain
Erector Spinae Plane Block Versus Transcutaneous Radiofrequency in Postherpetic Neuralgia
This observational study aims to compare the effectiveness of ultrasound-guided erector spinae plane (ESP) block and transcutaneous radiofrequency (RF) treatment in patients with postherpetic neuralgia.
- Conditions
- Postherpetic Neuralgia, Neuropathic Pain, Herpes Zoster
- Trial name
- NCT07400640
- Testing
- Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Diskapi Teaching and Research Hospital
Neuropathic Pain Induced by Mastectomy
Lidocaine IV Injection With Different Doses for Patients With Neuropathic Pain After Mastectomy
cancer has become the most common malignancy affecting women worldwide, and its incidence is increasing annually. According to the Global Cancer Observatory (GLOBOCAN) 2020 published by the International Agency for Research on…
- Trial name
- NCT07475520
- Testing
- Lidocaine 2%, Lidocaine
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Diabetes Mellitus, Diabetic Neuropathy
Effects of Ankle Block on Postoperative Analgesia in Diabetic and Non-Diabetic Patients
This prospective observational study aims to evaluate the effects of ultrasound-guided ankle block on sensory and motor block characteristics and postoperative analgesic outcomes in patients undergoing lower extremity surgery.
- Conditions
- Diabetes Mellitus, Diabetic Neuropathy, Postoperative Pain Management
- Trial name
- ANKLE-DM (NCT07404124)
- Testing
- Ultrasound-Guided Ankle Block
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Diabetic Peripheral Neuropathy
Exercise Effects on Pain, Sleep and Depression in Diabetic Peripheral Neuropathy
It is known that the pain experienced by individuals with diabetic neuropathy negatively impacts sleep and quality of life, leading to numerous psychosocial problems such as anxiety and depression.
- Trial name
- NCT07291596
- Testing
- Ankle-Foot Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Amasya University
Neuropathic Pain
Ketamine and Neuropathic Pain
The primary outcome is to compare the analgesic efficacy of intravenous ketamine treatment to that of a placebo in patients with refractory neuropathic pain. The secondary outcomes are: 1.
- Trial name
- KETAPAIN (NCT02467517)
- Testing
- Ketamine, Magnesium Sulfate
- Where
- France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Clermont-Ferrand
Transcranial Magnetic Stimulation, Complex Regional Pain Syndrome of Upper Limb (Disorder)
CRPS - Diagnostics, Pathophysiological Mechanisms, and Response to Treatment With Noninvasive Brain Stimulation
This is a sham controlled, randomized, double-blind, navigated repetitive Transcranial Magnetic Stimulation (nrTMS) study for the treatment of complex regional pain syndrome (CRPS types 1 and 2).
- Trial name
- NCT04439669
- Testing
- Active nrTMS and open phase
- Where
- 2 sites in Finland
- Volunteers
- 62 people
- Sponsor
- Helsinki University Central Hospital