Clinical trials: Painful Peripheral Neuropathy
Painful Diabetic Neuropathy
Trazodone in Painful Diabetic Neuropathy
The aim of the study is to collect preliminary information on the effect of low doses of trazodone on pain intensity in patients with painful diabetic neuropathy and to evaluate the neuropathic pain symptoms, anxiety, sleep…
- Trial name
- NCT03202979
- Testing
- Trazodone 20 mg, Trazodone 10 mg
- Where
- 20 sites in Czechia, Hungary and 1 more
- Volunteers
- 142 people
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Pudendal Neuralgia
Impact of Adding TENS to Conventional Physical Therapy Exercise on Pain Relief Among Patients With Pudendal Neuralgia.
Fifty two male participants, 30-50 years old, suffering from chronic pudendal neuralgia were randomly assigned either into experimental group (26 patients) received TENS plus the traditional physical therapy program( including…
- Trial name
- TENS (NCT04455659)
- Testing
- Trans-cutaneous Electrical Nerve Stimulation, Conventional physical therapy exercise
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Painful Polyneuropathy
Levetiracetam for Painful Polyneuropathy
Polyneuropathy of different etiologies is often associated with pain. The standard treatment of this pain is anticonvulsants or antidepressants, but none of these treatment are effective or tolerable for all patients.
- Trial name
- NCT00286260
- Testing
- levetiracetam
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Odense University Hospital
CRPS (Complex Regional Pain Syndromes)
Forward Looking InfraRed Imaging and Severity Score in Complex Regional Pain Syndrome
The goal of this interventional study is to explore the use of InfraRed (FLIR) imaging in determining pain intensity and severity in newly diagnosed complex regional pain syndrome patients.
- Trial name
- FLIR (NCT05852210)
- Testing
- Infrared Imaging
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hospital for Special Surgery, New York
Small-Fiber Neuropathy
Evaluation of Pregabalin in Idiopathic Small Fiber Neuropathy
Idiopathic Small Fiber Neuropathy (called SFN for short), is a condition where nerves that sense pain have become damaged, and often painful.
- Trial name
- NCT00787462
- Testing
- Pregabalin
- Where
- Canada
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Neuropathic Pain
Adrenocorticotropic Axis and Neuropathic Pain
Chronic pain is often associated with a chronic stress and HHSG axis plays a pivotal role in maintaining homeostasis. The literature reports that pain in patients treated with opioids, significant changes are taking place in this…
- Trial name
- HORMONES (NCT01543425)
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Sciatica, Electroacupuncture
Effectiveness of Electro-acupuncture and Manual Therapy on Pain and Fucntion in Patients With Sciatica
The aims of the study are: To study the pain efficacy of an electroacupuncture and manual therapy protocol versus the use of manual therapy in patients with sciatica.
- Conditions
- Sciatica, Electroacupuncture, Manual Therapy
- Trial name
- NCT04764890
- Testing
- Electroacupuncture, Manual therapy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- CEU San Pablo University
Sciatica Acute, Sciatica
COMPARISON OF EFFICACY OF DIFFERENT DRUG COMBINATIONS IN ACUTE SCIATICA
The goal of this clinical trial is to compare different combinations of diclofenac with diclofenac monotherapy in acute sciatica.
- Trial name
- EDCLAS (NCT05626140)
- Testing
- Lacosamide 50 MG Oral Tablet [Vimpat], Codeine Phosphate, Diclofenac Sodium
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Pakistan Institute of Medical Sciences
Pain, Neuropathic, Failed Back Surgery Syndrome
Coordinated Reset Spinal Cord Stimulation
The goal of this study is to evaluate whether a new spinal cord stimulation paradigm, called Coordinate Reset (CR) Stimulation, can provide equivalent or better pain relief with reduced energy requirements.
- Trial name
- NCT04997278
- Testing
- Coordinated Reset spinal cord stimulation
- Where
- United States
- Sponsor
- Stanford University
Diabetic Neuropathy, Painful
Tolerability of Switching to Duloxetine for the Management of Diabetic Nerve Pain
This study is to compare the tolerability of different methods for switching from another medication to duloxetine for the management of diabetic nerve pain.
- Trial name
- NCT00266643
- Testing
- duloxetine hydrochloride
- Where
- 20 sites in United States, Puerto Rico
- Volunteers
- 205 people
- Sponsor
- Eli Lilly and Company
Piriformis Syndrome
Comparative Effect of Active Release Technique Versus Self-myofascial Release in Improving Piriformis Syndrome
The goal of this Randomized controlled trial is to examine comparative effect of active release technique versus self-myofascial release in improving piriformis syndrome.
- Trial name
- NCT05742633
- Testing
- Active release technique, Self-myofascial release
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- Sehat Medical Complex
Neuropathic Pain
Lidocaine and Neuroma Pain Related Modalities
Background Subanesthetics concentrations of lidocaine are able to produce a differential block of the ectopic discharges, but not propagation of impulses, suppressing differentially the associated neuropathic pain symptoms.
- Trial name
- NCT02300038
- Testing
- Lidocaine (Xylocaine), NaCl
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Painful Diabetic Neuropathy, Diabetes
A Safety Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Painful Diabetic Neuropathy
Study CLO-311 is a multicenter, open-label, single-arm study to assess the long-term use of Clonidine Gel in the treatment of pain associated with PDN.
- Trial name
- NCT02355158
- Testing
- clonidine hydrochloride topical gel, 0.1%
- Where
- 20 sites in United States
- Volunteers
- 197 people
- Sponsor
- BioDelivery Sciences International
Patients With Neuropathic Pain Due to Peripheral Neuropathy
Investigating Modulation of Neuropathic Pain by Transcranial Magnetic Stimulation: a Multimodal Imaging and Electrophysiological Approach
The proposed project will combine functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) to identify neurobiological mechanisms underlying how repetitive transcranial magnetic stimulation (rTMS) applied to…
- Trial name
- NCT07758348
- Testing
- repetitive TMS
- Volunteers
- 52 people
- Sponsor
- National Taiwan University Hospital
Cervical Radiculopathy
Spinal Mobilization and PNF Comparison on Pain, Disability in Patients With Cervical Radiculopathy
As in this modern era of digitalization; mobile phones, touch pads and computers devices use is increasing, neck pain that radiates into upper limb is also becoming common due to such devices long term use in bad postures or…
- Trial name
- NCT06866821
- Testing
- SMWAM's and PNF C-R Technique, PNF C-R Technique and PT Protocol
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Dry Eye, Neuropathic Pain
Effect of Trigeminal Nerve Stimulation on Corneal Nerves and Chronic Ocular Pain
Individuals with dry eye tend to present with ocular pain which persists despite the use of topical treatment. This could be secondary to somatosensory impairment attributable to neuropathic pain.
- Conditions
- Dry Eye, Neuropathic Pain, Eye Pain
- Trial name
- NCT04648085
- Testing
- Trigeminal Nerve Stimulation
- Where
- Mexico
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Sciatica, Lumbar Disc Herniation
Electroacupuncture for Insomnia in Patients With Chronic Sciatica Due to Lumbar Disc Herniation: a Randomized Controlled Trial
The goal of this clinical trial is to learn if electroacupuncture can improve sleep in people with chronic sciatica caused by lumbar disc herniation. It will also assess the safety of this treatment.
- Conditions
- Sciatica, Lumbar Disc Herniation, Insomnia
- Trial name
- NCT07576348
- Testing
- Electroacupuncture
- Volunteers
- 114 people
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Spinal Stenosis Lumbar, Neuropathic Pain
Neuropathic Pain Severity and Its Association With Radiological Findings in Lumbar Spinal Stenosis
This cross-sectional observational study aims to evaluate neuropathic pain severity in patients with lumbar spinal stenosis (LSS) and to investigate its association with radiological findings.
- Trial name
- NCT07855445
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Carpal Tunnel Syndrome
Oral Gabapentin and Median Nerve Mobilization in the Treatment of Carpal Tunnel Syndrome
The present randomized clinical trial will perform a comparison of the pain reduction effects produced by the application of a non invasive and non pharmacological median nerve neural mobilization (physiotherapy treatment), to…
- Trial name
- NCT04285281
- Testing
- Gabapentin oral capsules, Median nerve neural mobilization
- Where
- Venezuela
- Volunteers
- 126 people
- Sponsor
- Universidad Europea de Madrid
Painful Diabetic Peripheral Neuropathy
The Effects of Ceylon Cinnamon (Cinnamomum Verum) Supplementation on Blood Glucose, Lipid Profile Levels, Body Mass Index, and Pain Intensity Among Adult Individuals With Painful Diabetic Peripheral Neuropathy
Background: Painful diabetic peripheral neuropathy (PDPN) is a severe, disabling complication of type 2 diabetes mellitus (T2DM), closely associated with insulin resistance, chronic neuroinflammation, and oxidative stress.
- Trial name
- PDPN- CC-RCT (NCT07743073)
- Testing
- Ceylon Cinnamon Supplement
- Where
- Jordan
- Volunteers
- 164 people
- Sponsor
- JAWAD AHMAD ABU-SHENNAR