Clinical trials: Painful Procedures in Newborns
Hemophilia
Fascial Therapy in Elbow Hemophilic Arthropathy
Introduction: The common clinical manifestations of hemophilia are skeletal muscle bleeds, especially hematomas and hemarthrosis. Repeated episodes of joint bleeding in certain joints, causing a progressive joint deterioration.
- Trial name
- HeL-Fascial (NCT03009591)
- Testing
- Experimental group
- Where
- Spain
- Volunteers
- 69 people
- Sponsor
- Real Fundación Victoria Eugenia
Pain, Acute, Infant, Newborn
The Influence of Skin-to-skin Contact on Cortical Activity During Painful Procedures on Preterm Infants in the NICU
The aim of this study is to examine the effect of SSC compared to sucrose on pain induced activity in the preterm infant brain using: a) series of low intensity experimental stimuli (PinPrick);and b) medically required heel…
- Conditions
- Pain, Acute, Infant, Newborn, Electroencephalography
- Trial name
- iCAPmini (NCT03745963)
- Testing
- Skin-to-skin contact, 24% oral sucrose
- Where
- Canada
- Volunteers
- 126 people
- Sponsor
- IWK Health Centre
Postoperative Pain
Postoperative Pain in Neonates After Abdominal Surgery Using Quadratus Lumborum Block
Postoperative pain scores and analgesic requirements will be evaluated in neonates after abdominal surgery, with regional quadratus lumborum block performed at the beginning of the procedure.
- Trial name
- NCT03203031
- Testing
- General anesthesia, Quadratus lumborum block
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Hôpital Armand Trousseau
Chronic Pain, Sickle Cell Disease
Mindfulness-Based Intervention for Pain and Sleep in Adolescents and Young Adults With Sickle Cell Disease
This study examines the feasibility and acceptability of a mindfulness-based mobile intervention designed to support pain and sleep management among adolescents and young adults with sickle cell disease.
- Conditions
- Chronic Pain, Sickle Cell Disease, Sleep Disturbance
- Trial name
- REMedy (NCT07402811)
- Testing
- Mobile bindfulness-based intervention
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Illinois at Chicago
Pacifier
Pacifier Use in Mechanically Ventilated Term Newborns
Newborns on mechanical ventilator; It is stated that they need to calm and soothe themselves, their coordination in sucking and swallowing reflexes is not good, they have aspiration risks, their weight gain and discharge are…
- Trial name
- NCT06170957
- Testing
- Modified pacifier
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hitit University
Pain
Comparison of the Efficacy of Oral Sucrose Administration at Two Different Times of a Painful Procedure in Neonates.
The objective of this study is to compare the use of 24% sucrose in pain control in neonates from 32 weeks of gestation onwards according to the time of administration of sucrose in venous and arterial puncture for blood…
- Trial name
- NCT05323071
- Testing
- Sucrose 24%
- Where
- Spain
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Oihana Lopez Alonso
Retinopathy of Prematurity, Pain
Pain in Neonates During Screening for Retinopathy of Prematurity Using Two Methods
Retinopathy of prematurity screening is painful. Wide field digital retinal imaging (WFDRI) and binocular indirect ophthalmoscopy (BIO) are being used for screening examinations.
- Trial name
- RETCAM (NCT00895869)
- Where
- United Kingdom
- Volunteers
- 76 people
- Sponsor
- NHS Lothian
Molar Incisor Hypomineralization, Hypersensitivity
Intraosseous vs Infiltration Anesthesia in Molar-Incisor Hypomineralization (MIH) Children
This study aims to compare the effectiveness of intraosseous and infiltration anesthesia techniques administered using a computer-assisted anesthesia device (SleeperOne® 5; Dental HiTec, France) during restorative treatments of…
- Trial name
- MIH (NCT07352813)
- Testing
- Intraosseous anaesthesia using a computerized system, Infiltration anaesthesia using a computerized system
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Pain, Newborn
The Effects of Different Procedures on Pain Levels at Preterm and Term Infants in Neonatal Intensive Care Unit
Accurate assessment of pain in neonates in the neonatal intensive care unit (NICU) is vital because of the high prevalence of painful experiences, including both daily procedural pain and postoperative pain, in this population.
- Conditions
- Pain, Newborn, Preterm, Term
- Trial name
- PAIN (NCT05077345)
- Where
- Turkey (Türkiye)
- Volunteers
- 196 people
- Sponsor
- Sanko University
Mechanically Ventilated Neonates, Painful Procedures in Newborns
Codeine in Mechanically Ventilated Neonates
The purpose of this study is to determine the absorption and bioavailability of codeine in relation to postnatal (PNA) and postconceptional (PCA) age; determine the parent drug (codeine), its active metabolites, their formation…
- Trial name
- NCT01322204
- Testing
- Codeine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Neonatal Pain, Non-Pharmacological Pain Management
Effect of Two Non-pharmacological Method on Pain, Stress Procedure Duration in Newborn
This study is planned as a prospective, single-blind, randomized controlled experimental study matched according to gestational age, gender, and birth weight, to determine the effects of local heat application and oral sucrose…
- Trial name
- NCT07125690
- Testing
- local heat application, oral sucrose, mixed group
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Sickle Cell Disease
Laboratory-based Hypnosis Intervention on Pain Responsivity in Adolescents With Sickle Cell Disease
The purpose of this study is to test the effects of a laboratory-based hypnosis session compared to an attention control condition on peripheral blood flow, autonomic stress responses, and acute pain responses in adolescents…
- Trial name
- NCT02987725
- Testing
- Hypnosis, Attention Control
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, Los Angeles
Pain, Preterm
The Nonpharmacological Methods in Reducing the Pain Caused by Orogastric Tube Insertion in Preterm Infants
According to the World Health Organization, preterm birth (from 20 to 37 gestation week) is a significant global health problem, as preterm infants represent an estimated 15 million infants per year worldwide.
- Conditions
- Pain, Preterm, Premature
- Trial name
- NCT04006743
- Testing
- The swaddling group, The expressed breast milk group, The facilitated tucking group
- Where
- Turkey (Türkiye)
- Volunteers
- 187 people
- Sponsor
- Akdeniz University
Pain
Music Therapy for Pain Management for Minor Procedures in Neonates.
The aim of this study is to assess the effectiveness and safety of music therapy as adjuvant therapy for pain management in newborns undergoing minor painful procedures.
- Trial name
- NCT04313179
- Testing
- Music therapy, Sucrose
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- New York City Health and Hospitals Corporation
Pain Management
Impact of Breast Milk on Cortical Pain Response in Newborns
Background:Newborns are exposed to painful procedures for many different reasons in the first days of their life. If pain is not relieved effectively in these newborns, neurodevelopmental and behavioral problems may occur in the…
- Trial name
- NCT05961904
- Testing
- Breastmilk
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Neuropathic Pain, Sickle Cell Disease
Sickle Cell Pain: Intervention With Capsaicin Exposure
This study evaluates the safety and feasibility of using high dose topical capsaicin patches for the treatment of neuropathic pain in pediatric patients with sickle cell disease, as well as the feasibility of using a number of…
- Trial name
- SPICE (NCT03899246)
- Testing
- Eight Percent Topical Capsaicin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Michigan
Heel Lance Procedures, Pain Management
The Effect of Su Jok Therapy on Pain During Heel LanceProcedure in Newborn
Objective: To determine the effect of Su Jok therapy on pain levels during the heel lance procedure in newborns. The study will be conducted as a randomized controlled experimental trial with a pretest-posttest control group…
- Trial name
- NCT07164820
- Testing
- Su Jok Application
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Heel Lance Procedures
Vibration and During Heel Lance Procedures in Newborns
This study aimed to evaluate the effect of applying vibration on pain during heel lance procedures in newborns. .
- Trial name
- NCT04674982
- Testing
- a vibrating device
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Hemophilia
Blood Flow Restriction in Improving Muscle Strength of Patients With Hemophilic Knee Arthropathy
Background. The main physical sequela of patients with hemophilia is the development of a progressive, degenerative intra-articular lesion, known as hemophilic arthropathy).
- Trial name
- NCT06261632
- Testing
- Blood flow restriction
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Sickle Cell Disease, Stress
The Feasibility of the PAINReportIt Guided Relaxation Intervention-Outpatient
Our goal is to improve the self-management of pain and stress in adult outpatients with sickle cell disease (SCD) by determining the feasibility of a self-managed guided relaxation (GR) stress reduction intervention using a…
- Conditions
- Sickle Cell Disease, Stress, Pain
- Trial name
- NCT02729363
- Testing
- Guided Relaxation video clip, Sickle Cell Disease Experience Discussion
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida