Clinical trials: Painful Procedures in Newborns
Hernia, Umbilical, Clonidine
Clonidine in Ultrasound-guided Rectus Sheath Block for Outpatient Umbilical Hernioplasty
This clinical trial aims to evaluate the effectiveness of an ultrasound-guided nerve block technique as the sole anesthetic method for patients undergoing outpatient umbilical hernia surgery.
- Conditions
- Hernia, Umbilical, Clonidine, Pain, Postoperative, Ambulatory Surgical Procedures
- Trial name
- NCT07062497
- Testing
- Rectus Sheath Block, Rectus Sheath Block with Clonidine
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Neonatal Pain, Non-Pharmacological Pain Management
Effect of Two Non-pharmacological Method on Pain, Stress Procedure Duration in Newborn
This study is planned as a prospective, single-blind, randomized controlled experimental study matched according to gestational age, gender, and birth weight, to determine the effects of local heat application and oral sucrose…
- Trial name
- NCT07125690
- Testing
- local heat application, oral sucrose, mixed group
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Cryptorchidism
Comparing Oxygen Saturation in Post Anesthesia Care Unit After Different Methods of Pain Relief
To determine the which method of pain relief is better after current anesthesia care.
- Trial name
- NCT00435383
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Procedural Pain, Heel Prick
ShotBlocker and Warm Gel Pack During Neonatal Heel Prick (HEAL)
This study evaluated the effects of ShotBlocker and a warm gel pack on pain, comfort, and physiological parameters during heel prick testing in healthy term newborns.
- Conditions
- Procedural Pain, Heel Prick, Newborn
- Trial name
- HEAL (NCT07686627)
- Testing
- ShotBlocker, Warm Gel Pack
- Where
- Turkey (Türkiye)
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Marmara University
Pain, Infant ALL
The Effect of Non-pharmacological Methods on Pain
The research will be conducted using a randomized controlled experimental method.The preterm newborns included in the study will be randomized into three groups using the sealed envelope method.
- Conditions
- Pain, Infant ALL, Preterm
- Trial name
- NCT06455631
- Testing
- Facilitated Tucking, Oral Breast Milk , Kangaroo Care
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fenerbahce University
Chronic Kidney Diseases, Pain, Procedural
Effect of 4-7-8 Breathing on AV Fistula Needle Pain in Dialysis Patients
For many hemodialysis patients, needle insertion into the vascular access site (fistula) is a significant source of pain and anxiety.
- Conditions
- Chronic Kidney Diseases, Pain, Procedural, Arteriovenous Fistula
- Trial name
- NCT07700680
- Testing
- Breathing technique
- Volunteers
- 80 people
- Sponsor
- Izmir Kavram Vocational School
Pain Control in Heel Prick Procedure
Comparing 0.2 ml and 0.5 ml Oral 24% Sucrose Solution for Pain Relief During Heel Prick in Neonates With Historical Controls
The goal of this clinical trial is to determine whether a lower dose of oral 24% sucrose solution provides pain relief that is non-inferior to a higher dose during routine heel-prick procedures in term neonates.
- Trial name
- Sucrose (NCT07784322)
- Testing
- 24% oral sucrose
- Where
- Hong Kong
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kwong Wah Hospital
Chronic Pain, Sickle Cell Disease
Mindfulness-Based Intervention for Pain and Sleep in Adolescents and Young Adults With Sickle Cell Disease
This study examines the feasibility and acceptability of a mindfulness-based mobile intervention designed to support pain and sleep management among adolescents and young adults with sickle cell disease.
- Conditions
- Chronic Pain, Sickle Cell Disease, Sleep Disturbance
- Trial name
- REMedy (NCT07402811)
- Testing
- Mobile bindfulness-based intervention
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Illinois at Chicago
Hemophilia
Restricting Blood Flow in Improving Muscle Strength in Patients With Hemophilic Arthropathy
Background. The main physical sequela of patients with hemophilia is the development of a progressive, degenerative intra-articular lesion, known as hemophilic arthropathy).
- Trial name
- NCT05039008
- Testing
- Blood flow restriction
- Where
- Spain
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Hemophilia
Fascial Therapy in Elbow Hemophilic Arthropathy
Introduction: The common clinical manifestations of hemophilia are skeletal muscle bleeds, especially hematomas and hemarthrosis. Repeated episodes of joint bleeding in certain joints, causing a progressive joint deterioration.
- Trial name
- HeL-Fascial (NCT03009591)
- Testing
- Experimental group
- Where
- Spain
- Volunteers
- 69 people
- Sponsor
- Real Fundación Victoria Eugenia
Sickle Cell Disease
Laboratory-based Hypnosis Intervention on Pain Responsivity in Adolescents With Sickle Cell Disease
The purpose of this study is to test the effects of a laboratory-based hypnosis session compared to an attention control condition on peripheral blood flow, autonomic stress responses, and acute pain responses in adolescents…
- Trial name
- NCT02987725
- Testing
- Hypnosis, Attention Control
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, Los Angeles
Sickle Cell Disease, Stress
The Feasibility of the PAINReportIt Guided Relaxation Intervention-Outpatient
Our goal is to improve the self-management of pain and stress in adult outpatients with sickle cell disease (SCD) by determining the feasibility of a self-managed guided relaxation (GR) stress reduction intervention using a…
- Conditions
- Sickle Cell Disease, Stress, Pain
- Trial name
- NCT02729363
- Testing
- Guided Relaxation video clip, Sickle Cell Disease Experience Discussion
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
Chronic Pain, Sickle Cell Disease
MBI for Pain and Sleep in Adolescents and Young Adults With Sickle Cell Disease
This study examines the efficacy of a mindfulness-based intervention designed to support pain and sleep management in adolescents and young adults with sickle cell disease.
- Conditions
- Chronic Pain, Sickle Cell Disease, Sleep
- Trial name
- REMedy_RCT (NCT07797582)
- Testing
- Mindfulness-based intervention
- Volunteers
- 48 people
- Sponsor
- University of Illinois at Chicago
Molar Incisor Hypomineralization, Hypersensitivity
Intraosseous vs Infiltration Anesthesia in Molar-Incisor Hypomineralization (MIH) Children
This study aims to compare the effectiveness of intraosseous and infiltration anesthesia techniques administered using a computer-assisted anesthesia device (SleeperOne® 5; Dental HiTec, France) during restorative treatments of…
- Trial name
- MIH (NCT07352813)
- Testing
- Intraosseous anaesthesia using a computerized system, Infiltration anaesthesia using a computerized system
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Sickle Cell Disease, Stress
The Feasibility of the PAINReportIt Guided Relaxation Intervention-INPATIENT
The goal of this research study is to improve the self-management of pain, stress, and cognitive/affective symptoms that may result in adult inpatients with sickle cell disease (SCD) by determining the feasibility of a…
- Conditions
- Sickle Cell Disease, Stress, Pain
- Trial name
- NCT02729350
- Testing
- Guided Relaxation video clip, Sickle Cell Disease Experience Discussion
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Florida
Pain
Musical Intervention During IV-line Placement in Neonates
The goal of this clinical trial is to test the effect of music in reducing the pain felt by newborn children during an intravenous line procedure. An intravenous line is a small tube brought into a vein by using a needle.
- Trial name
- NCT05926921
- Testing
- music
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Spaarne Gasthuis
Preterm Neonates, Heel Lance Procedures
Crochet Octopus in Reducing Procedural Pain During Heel Lance in Preterm Neonates
Neonates, particularly those hospitalized in neonatal intensive care units (NICUs), are subjected to numerous painful procedures essential for their diagnosis and monitoring.
- Conditions
- Preterm Neonates, Heel Lance Procedures, Procedural Pain
- Trial name
- RCT (NCT07828795)
- Testing
- Crochet Octopus
- Volunteers
- 98 people
- Sponsor
- Mansoura University
Procedural Pain, Preterm Infants
Effectiveness of Gentle Touch Technique on Pain Level During Painful Procedures in Preterm Infants
Preterm infants in neonatal intensive care units frequently undergo painful procedures that may affect their physiological stability, including pain level and respiratory parameters.
- Trial name
- NCT07470398
- Testing
- Gentle Touch Technique
- Where
- 3 sites in Iraq
- Volunteers
- 60 people
- Sponsor
- Karbala University
Pacifier
Pacifier Use in Mechanically Ventilated Term Newborns
Newborns on mechanical ventilator; It is stated that they need to calm and soothe themselves, their coordination in sucking and swallowing reflexes is not good, they have aspiration risks, their weight gain and discharge are…
- Trial name
- NCT06170957
- Testing
- Modified pacifier
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hitit University
Scoliosis, Pectus Excavatum
Hypnotherapy in Major Surgical Procedures
The purpose of this randomized controlled study is to test the feasibility of clinical hypnotherapy as a perioperative intervention for the reduction of pre-operative anxiety, post-operative pain, and other-related symptoms…
- Trial name
- NCT02376634
- Testing
- Hypnosis
- Where
- United States
- Sponsor
- Nationwide Children's Hospital