Clinical trials: Palliative
Gastric Cancer
Palliative Radiotherapy for Symptomatic Locally Advanced Gastric Cancer: A Phase II Trial
The hypothesis of this study is that a radiotherapy dose of 36Gy in 12 fractions, which equates to a BED of 48.6Gy, increases the response rates of symptom relief compared to historical controls.
- Trial name
- NCT01341756
- Testing
- Palliative Radiotherapy
- Where
- Singapore
- Volunteers
- 63 people
- Sponsor
- National University Hospital, Singapore
Aging Problems
Enhancing Care of the Aged and Dying in Prisons Ph II
The mission of corrections is to provide custody, control and care for incarcerated individuals. United States prisons are required by constitutional law to provide adequate care for growing numbers of older inmates who will…
- Trial name
- NCT03055429
- Testing
- Full Scale Unit
- Where
- 2 sites in United States
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Advanced Cancer
Balance, Activity and Quality of Life
Background: Advanced cancer may cause functional limitations, subsequently leading to decreased ability to perform and engage in everyday activities, such as self-care, household, leisure and civic life.
- Trial name
- BAL (NCT04772690)
- Testing
- A resource-oriented intervention
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- REHPA, The Danish Knowledge Centre for Rehabilitation and Palliative Care
Psychological Distress
Psilocybin Microdose for Psychological and Existential Distress in Palliative Care (PSYCHED-PAL-RCT)
About 30-50% of patients with advanced illness experience depression, anxiety, or decreased sense of purpose and autonomy. Together, these are called psychological distress.
- Trial name
- NCT07063862
- Testing
- Psilocybin
- Where
- 7 sites in Canada
- Volunteers
- 120 people
- Sponsor
- Bruyère Health Research Institute.
Myofascial Pain Syndromes, Cancer
Efficacy of Myofascial Pain Syndrome Treatment in Patients With Cancer in Palliative Care
Palliative Care is active holistic care offered to people who are in intense suffering related to their health, resulting from a serious life-threatening illness, with a focus on improving the quality of life.
- Trial name
- NCT04703803
- Testing
- 1% lidocaine injection in trigger points
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Gynaecological Cancer
Palliation in Gynae-oncology: Patients Expectations and Assessment of Care (PEACE)
The overall aim is to assess the feasibility and acceptability of collecting data on the patients and carers perception of care as well as to prospectively monitor end of life care.
- Trial name
- PEACE (NCT05142150)
- Testing
- Questionaire
- Where
- Norway
- Volunteers
- 73 people
- Sponsor
- Nordic Society of Gynaecological Oncology - Clinical Trials Unit
Cancer, Palliative Care
Music Therapy for Cancer Patients(Meraki_PC)
The overall aim of the study is to analyse the impact of a music therapy-based treatment on the emotional well-being and quality of life of cancer patients in palliative care (PC).
- Trial name
- Meraki_Cancer (NCT06345924)
- Testing
- MERAKI_PC
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- University of Valencia
Peripherally Inserted Central Catheter, Intravenous Access
Comparison Between Initial Routine PICC and General IV Access in Terminally Ill Cancer Patients
To establish the IV access strategy for terminally ill cancer patients, using comparisons of the safety, efficacy, and patient-perceived satisfaction between the initially routine PICC insertion group (routine PICC group) and…
- Trial name
- NCT03299868
- Testing
- peripherally inserted central catheter (PICC)
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Pusan National University Yangsan Hospital
Cholangiocarcinoma
the Impact of Early Palliative Care on the Survival of Locally Advanced and / or Metastatic Cholangiocarcinoma Patients
The prognosis for cholangiocarcinoma is bad. Potentially, early management by a palliative care team could increase overall survival.
- Trial name
- NCT04415190
- Testing
- early palliative care
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Central Hospital, Nancy, France
Pancreatic Cancer
Endoscopic Stenting Versus Surgical Bypass for Low Bile Duct Obstruction by Cancer of the Pancreatic Head
The prognosis of patients with unresectable pancreatic cancer is dismal. Hence, palliation of tumor-associated symptoms, in particular jaundice due to low bile duct obstruction and gastric outlet obstruction, is the primary aim…
- Trial name
- STENTBY (NCT00753441)
- Testing
- Surgical bypass, Endoscopic stenting
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Heidelberg University
Cholangiocarcinoma
Photodynamic Therapy (PDT) Trial for Palliation of Cholangiocarcinoma
This research study is a phase III double arm, multicenter, randomized controlled clinical trial comparing endoscopic retrograde cholangiopancreatography (ERCP) and stenting plus photodynamic therapy (PDT) versus ERCP with…
- Trial name
- PDT (NCT00907413)
- Testing
- ERCP and Photodynamic Therapy, ERCP only
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Weill Medical College of Cornell University
Cancer
Evaluate the Effectiveness of Low Level Laser Therapy (LLT) Combined With Acupuncture
evaluating The Investigational Therapy effects on quality of life, pain and patient's clinical status in adult cancer patients with solid tumors who are no longer candidates for active oncological therapies.
- Trial name
- NCT02686203
- Testing
- B-Cure Laser Pro and needles
- Volunteers
- 30 people
- Sponsor
- Erika Carmel ltd
Chronic Heart Failure
Collaborative Care to Alleviate Symptoms and Adjust to Illness in Chronic Heart Failure (CASA) Trial
Chronic heart failure is an important public health problem as it is a leading cause of disability, hospitalization, death, and costs.
- Trial name
- CASA (NCT01739686)
- Testing
- CASA Intervention
- Where
- 3 sites in United States
- Volunteers
- 317 people
- Sponsor
- Denver Research Institute
Palliative Care
Antithrombotic Therapy at the End of Life: The PEACE Study
"Antithrombotic Therapy at the End of Life: The PEACE Study" is a multicenter, non-profit, cross-sectional observational study. In the absence of shared guidelines, therapeutic decisions on antithrombotic drugs vary significantly…
- Trial name
- PEACE (NCT07338071)
- Testing
- antithrombotic drugs
- Where
- Italy
- Volunteers
- 410 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Head and Neck Cancer, Radiotherapy
Short Course Radiation Therapy in Palliative Treatment of Head and Neck Cancer
Aim of the study is to assess efficacy of a short course radiation treatment in patients with symptomatic head and neck (H\&N) malignant lesions
- Conditions
- Head and Neck Cancer, Radiotherapy, Palliative Care
- Trial name
- NCT03804073
- Testing
- standard treatment, short course treatment
- Where
- Italy
- Volunteers
- 82 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Respiratory Inflammation
Oral Essential Oils Efficacy in Acute Respiratory Symptoms
The goal of this clinical trial is to explore the impact of a dietary supplement containing essential oils on symptom severity in patients presenting to the ED with respiratory complaints.
- Trial name
- NCT07518394
- Testing
- essential oils of eucalyptus, thyme, cinnamon, lavender, winter savory, tea tree, camphor tree
- Where
- Tunisia
- Volunteers
- 105 people
- Sponsor
- University of Sfax
Neoplasia Prostate
PALLiON - PALLiative Care In ONcology
A major concern in today's oncology is the complexity of treatment that increases costs. A main contributor is the increasing use of chemo- and radiotherapy during end of life (EoL: the last 12 months of life).
- Trial name
- PALLiON (NCT03088202)
- Testing
- Educational program, Standardized care pathways, Early palliative care
- Where
- 12 sites in Norway
- Volunteers
- 659 people
- Sponsor
- Oslo University Hospital
Lung Disease
Evaluation of the Hospital2Home Palliative Care Service for Patients With Advanced Progressive Lung Disease
The investigators hypothesise that H2H will result in improved symptom control and quality of life and may be more cost-effective than standard best practice.
- Trial name
- H2H-ILD (NCT01450644)
- Testing
- The Hospital2Home Service
- Where
- 2 sites in United Kingdom
- Volunteers
- 52 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Metastatic Head and Neck Squamous Cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma
Durvalumab, Tremelimumab and Hypofractionated Radiation Therapy in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
This phase I/II trial studies the side effects of durvalumab, tremelimumab and hypofractionated radiation therapy in treating patients with head and neck squamous cell carcinoma that has come back (recurrent) or that has spread…
- Trial name
- NCT03522584
- Testing
- Durvalumab, Laboratory Biomarker Analysis, Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Washington
Renal Cell Carcinoma
Study of Sorafenib and Palliative Radiotherapy in Kidney Cancer That Spreads to the Bone
The purpose of this study is to investigate the use of a new anti-angiogenic drug called sorafenib, in combination with radiotherapy, for renal cell cancer that has spread to the bone and is causing significant pain.
- Trial name
- NCT00609934
- Testing
- Sorafenib, external beam radiotherapy
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University Health Network, Toronto