Clinical trials: Palliative
Bone Metastases, Radiotherapy
Single frActIoN eighT Gray Palliative Radiotherapy With Modulated Intensity for Pain Reduction
Non-randomized, monocentric, observational study to evaluate the response in terms of reduction of painful symptoms from bone metastases to radiotherapy with high personalization of treatment: performed with modern technology…
- Conditions
- Bone Metastases, Radiotherapy, Technology
- Trial name
- SAINT (NCT03554135)
- Testing
- Personalization of palliative radiotherapy
- Volunteers
- 50 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hepatocellular Carcinoma, Hepatic Metastasis
Palliative Radiotherapy (RT) for Liver Metastases (Mets) and Hepatocellular Carcinoma (HCC)(COLD 4)
Palliative radiotherapy is radiation treatment given to help reduce pain or discomfort, or other symptoms related to cancer. This is used commonly for cancer that has spread to the bones and brain, and for many other primary…
- Trial name
- NCT00923897
- Testing
- Palliative RT
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Advanced Medical Illness
Integrating Palliative Care Social Workers Into Sub-Acute Settings: A Feasibility Trial
This is a feasibility trial utilizing a step wedge design of a social worker led palliative care intervention for 120 adult patients with advanced medical illness being cared for in a subacute nursing facility.
- Trial name
- ALIGN (NCT03546920)
- Testing
- ALIGN Intervention Phase
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Colorado, Denver
Multiple Sclerosis, Chronic Pain
MS Symptom Management Study
People with Multiple Sclerosis (MS) often have pain and/or fatigue. Unfortunately, available treatments provide inadequate relief for the majority of these individuals.
- Conditions
- Multiple Sclerosis, Chronic Pain, Fatigue
- Trial name
- ENHANCE (NCT02474940)
- Testing
- Intervention #1, Intervention #2, Intervention #3
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Washington
Heart Failure
The Effect of Video Training o Symptom Management With Heart Failure
The purpose of this clinical study is to compare the effect of video-assisted training on the quality of life and symptom management of patients over the age of 65.
- Trial name
- NCT06068725
- Testing
- Training videos
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Ege University
Palliative Care, Virtual Reality
Virtual Reality Within Palliative Care (VR-SPC)
Literature so far shows VR is largely acceptable and feasible to use in palliative care settings, especially for improving patient wellbeing and mental health.
- Conditions
- Palliative Care, Virtual Reality, Wellbeing
- Trial name
- VR-SPC (NCT07109050)
- Testing
- VR Headset
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Lincoln
Opioid Use, Constipation Drug Induced
Study on Quality of Life in Advanced Cancer Patients With Opioid-induced Constipation Treated With Naloxegol
Opioid-Induced Constipation (OIC) is often associated with a compromised quality of life of patients in palliative care (PC) setting.
- Conditions
- Opioid Use, Constipation Drug Induced, Cancer
- Trial name
- NCT04294550
- Testing
- Naloxegol
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Fondazione ANT Franco Pannuti ETS
Major Depressive Disorder, Advanced Cancer
Ketamine or Placebo in Patients With Major Depression and Advanced Cancer
Major depression (MD) is a psychiatric disorder characterized by a persistent feeling of sadness, anhedonia or a decreased perception of pleasurable experiences, as well as appetite alterations and weight variations, sleep…
- Trial name
- KODIAC (NCT04471818)
- Testing
- Ketamine
- Where
- Mexico
- Volunteers
- 19 people
- Sponsor
- Instituto Nacional de Cancerologia de Mexico
Relatives, Health Care Providers
A Complex Intervention Study on a Palliative Rehabilitation Blended Learning Program to Support Relatives and Health Care Providers of People With ALS and Cognitive Impairments in Coping With Challenges
A complex intervention study on a palliative rehabilitation blended learning program to support relatives and health care providers of people with ALS and cognitive impairments in coping with challenges.
- Conditions
- Relatives, Health Care Providers, Cognitive Impairment, Rehabilitation
- Trial name
- NCT04638608
- Testing
- EMBRACE (relatives), EMBRACE (Health care providers)
- Where
- Denmark
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Danish Rehabilitation Centre for Neuromuscular Diseases
Dyspnea
Interdisciplinary Approach for Refractory Dyspnoea
Dyspnoea is a very common symptom in many diseases, not only cardiorespiratory, but also renal or neurological diseases. It can be defined as " difficult, laboured and uncomfortable breathing […]. It is a subjective symptom.
- Trial name
- NCT04015817
- Testing
- paramedical and non-pharmacological services
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- Ligue Pulmonaire Neuchâteloise
Advanced Gastric Cancer
A Randomized Controlled Trial of Integrated Early Palliative Care for Advanced Gastric Cancer Patients
Cancer patients and their families constantly face physical, psychosocial, economic, and existential problems, but palliative care to solve and prevent them is currently applied only at a late stage in Korean medical practice…
- Trial name
- NCT05584592
- Testing
- Intergrate early palliatuve care + Conventional chemotherapy, Conventional chemotherapy
- Where
- South Korea
- Volunteers
- 170 people
- Sponsor
- Yonsei University
Cancer
Influence of Dietary and Palliative Care Consultation on the Quality of Life (Qol), Performance Status, and Nutritional Status of Cancer Patients in Bangladesh
Cancer patients are more likely to have malnutrition, which has been associated with poorer quality of life, higher morbidity, mortality rates, and impaired efficacy and tolerance to therapy.
- Trial name
- Consult Cancer (NCT06971263)
- Testing
- Consultation on both nutrition, and palliative care, Counselling on nutrition and healthy diet
- Where
- 3 sites in Bangladesh
- Volunteers
- 215 people
- Sponsor
- Jahangirnagar University
Gastric Cancer, Bleeding
The Use of Proton Pump Inhibitor on the Prevention of Gastric Cancer Bleeding
The aim of this study is the effect of proton pump inhibitor (PPI) with respect to gastric cancer bleeding in inoperable patients.
- Trial name
- NCT02150447
- Testing
- Proton pump inhibitor
- Where
- 4 sites in South Korea
- Volunteers
- 394 people
- Sponsor
- National Cancer Center, Korea
End of Life, Support, Family
User Testing of an End of Life Medication Support Intervention for Lay Carers (Palliate).
The aim of this study is to evaluate the acceptability, safety and efficiency of the Palliate intervention. The Palliate intervention is a nurse-led process that includes training and documentation materials to support lay carers…
- Trial name
- NCT06526637
- Testing
- Paper Package, V1 + Preparation Sheet, V2 + Video Training
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Advance Care Planning, Palliative Care
Testing a Video Decision Support Tool to Supplement Goals-of-Care Discussions
Subject preferences for care at the end-of-life show wide variability. In the setting of advanced disease, some subjects prefer all life-sustaining care while others forgo such procedures.
- Trial name
- NCT01391429
- Testing
- Video Decision Support Tool
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Boston Medical Center
Family Caregivers
Supporting Family Carers to People Living With Symptoms of Dementia at Home up to the End of Life
This is a qualitative study that will seek to gain further understanding of the support needs of family carers to people living with symptoms of dementia up to the end of life.
- Trial name
- NCT03666611
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Breast Cancer Survivorship
To Live Better After Breast Cancer Treatment
The most common cancer among women in Sweden is breast cancer. Advances in treatment have improved survival, but these advances have come at a steep price since most treatments impose substantial morbidity and burden on patients…
- Trial name
- NCT06471452
- Testing
- Interaktor
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Unresectable Hilar Cholangiocarcinoma
Quality of Life in Patients With Unresectable Hilar Cholangiocarcinoma on Palliative Metallic Stent Versus Plastic Stent
The purpose of this study is to compare the quality of life in patients with unresectable hilar cholangiocarcinoma on palliative metallic stent versus plastic Stent.
- Trial name
- NCT00746538
- Testing
- biliary stent
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Khon Kaen University
Palliative Care
Impact of Medicalized Residential Care (LAM) on the Development of Care Plans for Vulnerable Patients in Palliative Care
The aim of the research is to identify the factors influencing the development of care plans for vulnerable patients admitted to medicalized care facilities (LAM) and in palliative care.
- Trial name
- LAM-SP (NCT07342985)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Sarcoma, Thoracic Cancer
Palliative Lattice Stereotactic Body Radiotherapy (SBRT) for Patients With Sarcoma, Thoracic, Abdominal, and Pelvic Cancers
This is a study evaluating the safety and efficacy of Lattice SBRT for patients with large tumors (≥ 4.5 cm) planning to undergo palliative radiotherapy.
- Conditions
- Sarcoma, Thoracic Cancer, Abdominal Cancer, Pelvic Cancer
- Trial name
- NCT04553471
- Testing
- Stereotactic body radiotherapy, Research blood draw
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Washington University School of Medicine