Clinical trials: Palliative Cancer
Cancer
Palliative Care Study in Patients With Advanced Cancer
The purpose of this study is to determine whether patients with advanced cancers who receive AVR118 solution for injection into the skin can achieve improvement in quality of life.
- Trial name
- NCT00127517
- Testing
- peptide-nucleic acid solution AVR118
- Where
- 3 sites in United States
- Sponsor
- Advanced Viral Research Corp
Major Depressive Disorder, Advanced Cancer
Ketamine or Placebo in Patients With Major Depression and Advanced Cancer
Major depression (MD) is a psychiatric disorder characterized by a persistent feeling of sadness, anhedonia or a decreased perception of pleasurable experiences, as well as appetite alterations and weight variations, sleep…
- Trial name
- KODIAC (NCT04471818)
- Testing
- Ketamine
- Where
- Mexico
- Volunteers
- 19 people
- Sponsor
- Instituto Nacional de Cancerologia de Mexico
Advanced Malignant Neoplasm, Pain
Rectal Administration of Opioids Using the Macy Catheter in Reducing Pain in Patients With Advanced Cancer
This trial studies how well rectal administration of opioids using the Macy catheter works in reducing pain in patients with cancer that has spread to other anatomic sites or is no longer responding to treatment.
- Trial name
- NCT03592459
- Testing
- Macy Catheter, Pain Therapy, Questionnaire Administration
- Where
- United States
- Sponsor
- M.D. Anderson Cancer Center
Prostate Cancer
Symptom Management, Education and Telephone Follow-up, Quality of Life,
This study was planned as an experimental design study with pretest-posttest control group in order to determine the effects of education and telephone follow-up given to patients receiving androgen deprivation therapy (ADT) for…
- Trial name
- NCT05613881
- Testing
- Education and Telephone Follow-up
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Quality of Life Outcomes
Palliative Care Integration in Pediatric Oncology Phase 1 Clinical Trials
Although cure rates continue to rise, one in five children with cancer still die from their disease, so new therapies are urgently needed.
- Trial name
- NCT07696065
- Testing
- Pediatric Palliative Care Consultation
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Phoenix Children's Hospital
Metastatic Gastric Cancer, Surgery
Clinical Outcome of Palliative Surgery After Translational Therapy for Metastatic Gastric Cancer Versus Maintenance Chemotherapy for Metastatic Gastric Cancer
This single-center, prospective study was conducted to investigate the efficacy and safety of palliative surgery after translational therapy in the treatment of metastatic gastric cancer.
- Conditions
- Metastatic Gastric Cancer, Surgery, Chemotherapy
- Trial name
- NCT05230771
- Testing
- Palliative surgery after translational therapy, Chemotheraoy along
- Volunteers
- 120 people
- Sponsor
- Fujian Medical University
Lung Cancer
Effects of Palliative Care on Quality of Life and Symptom Control in Patients With Stage I, Stage II, or Stage IIIA Non-Small Cell Lung Cancer That Can Be Removed by Surgery
RATIONALE: Palliative care may be more effective than standard care in improving quality of life and symptoms in patients with lung cancer.
- Trial name
- NCT00823667
- Testing
- educational intervention, medical chart review, questionnaire administration
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- City of Hope Medical Center
Pain, Palliative Care
Efficacy and Safety Study of Fentanyl Transdermal (Fentanest®)
Eligible patients who agree to participate will migrate from oral opioids to transdermal patches and be followed for four weeks. Oral morphine will be provided as pain rescue medication.
- Trial name
- NCT00959400
- Testing
- Fentanyl Transdermal
- Where
- 5 sites in Brazil
- Sponsor
- Cristália Produtos Químicos Farmacêuticos Ltda.
Multidisciplinary Collaborative, Palliative Care Model
The Clinical Effect of Palliative Treatment on Patients With Terminal Cancer
This study proposed a multidisciplinary collaborative team combined with a palliative care model and proposed to establish a team composed of medical staff in various disciplines to make up for the defects of a conventional…
- Conditions
- Multidisciplinary Collaborative, Palliative Care Model, Quality of Life
- Trial name
- NCT05683236
- Testing
- Health education, Comfort care, Pain care
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shijiazhuang People's Hospital
Neoplasm Metastasis
Pilot Study to Test the Feasibility and the Efficacy of the German Language Adapted PRO-SELF© Plus Pain Control Program
The purpose of this pilot study is to refine and test an advanced and adapted German version of the PRO-SELF© Plus Pain Control Program (PCP), an educational intervention directed at cancer pain patients and their families to…
- Trial name
- PEINCA (NCT00920504)
- Testing
- German PRO-SELF(c) Plus Pain Control Program (PCP), Standard Care
- Where
- Germany
- Volunteers
- 39 people
- Sponsor
- University Hospital, Basel, Switzerland
Colorectal Cancer, Pancreatic Cancer
Quality of Life of Patients Over 75 Yars Undergoing Palliative Chemotherapy
The aim of this research is to evaluate the quality of life of patients over 75 years of age undergoing palliative chemotherapy for digestive cancer.
- Conditions
- Colorectal Cancer, Pancreatic Cancer, Biliary Cancer, Hepatic Cancer
- Trial name
- EQLVCPAL (NCT04517448)
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Centre Hospitalier de la côte Basque
Breast Cancer, Fatigue
Initial Assessment of an Internet-based Symptom Management Intervention in Early Stage Breast Cancer
In order to determine the acceptability of a breast cancer-specific cognitive behavioral therapy intervention, as well as to obtain preliminary data to assess efficacy in managing symptoms, the investigators will ask 45 breast…
- Conditions
- Breast Cancer, Fatigue, Insomnia, Pain
- Trial name
- PROSPECT (NCT02495155)
- Testing
- PROSPECT
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Michigan
Lung Cancers
An Evaluation of Dose-escalation for Intrathoracic Tumours
This is a pragmatic trial with patients randomized between standard of care palliative thoracic radiation therapy (RT) vs. hypofractionated, dose-escalated, esophageal-sparing (HD-ES) intensity modulated radiation therapy (IMRT).
- Trial name
- PREVENT-LUNG (NCT06794125)
- Testing
- Hypofractionated Radiation Therapy, Radiation Therapy
- Where
- 4 sites in Canada
- Volunteers
- 141 people
- Sponsor
- Chris Goodman
Cachexia, Cancer
Effectiveness of Nutritional Counselling and "Improved Atta" Supplementation in Cachexic Adult Indian Cancer Patients
Investigators are evaluating the nutritional role of IAtta supplementation along with nutritional counselling in delaying the progression of cachexia to refractory cachexia in adult cancer Indian patients.
- Trial name
- NCT02561143
- Testing
- Improved Atta, Wheat flour, Physical activity counseling
- Where
- 2 sites in India, United Kingdom
- Volunteers
- 150 people
- Sponsor
- University of Westminster
Cancer, Cancer (Active Cancer, Meaning Not Being Cancer Free), of Any Stage and Involving Any Treatment/Care Regimen; i.e. Curative, Life-extending, or Palliative
Is the 1939 Cancer Act Fit for Purpose in the Modern Technology Era?
The 1939 Cancer Act in the UK (England \& Wales) prohibits advertising of cancer treatments to the public, by anyone but the NHS.
- Conditions
- Cancer, Cancer (Active Cancer, Meaning Not Being Cancer Free), of Any Stage and Involving Any Treatment/Care Regimen; i.e. Curative, Life-extending, or Palliative, Cancer (Solid Tumors), Cancer (With or Without Metastasis)
- Trial name
- NCT07584824
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Royal Cornwall Hospitals Trust
End Stage Cancer
Artificial Intelligence-based Mortality Prediction Among Cancer Patients in the Hospice Ward
The purpose of this study is to develop a novel deep-learning-based survival prediction model employing patient activity data recorded by a wearable device.
- Trial name
- NCT04883879
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Medical University
Cancer, Chronic Heart Failure
Palliative Outcome Evaluation Muenster I
For patients with an advanced disease and their families an excellent and compassionate care is essential. However, in hospitals optimal end-of-life care is not yet fully realized and patient's needs are often not met.
- Conditions
- Cancer, Chronic Heart Failure, COPD Exacerbation, Palliative Care
- Trial name
- POEM I (NCT03286127)
- Testing
- specialized palliative care
- Where
- 5 sites in Germany
- Volunteers
- 347 people
- Sponsor
- University Hospital Muenster
Large Tumor, Palliative Radiotherapy
Lattice Radiotherapy for Adults With Large Tumors
The purpose of this study is to ask whether using a specialized radiation therapy technique called Lattice Radiation Therapy (LRT) can shrink large tumors when given with palliative radiation therapy.
- Trial name
- LRT (NCT07647679)
- Testing
- Lattice Radiation Therapy (LRT)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Duke University
Medical Oncology, Cardiology
Results From a Health System-wide Implementation of a Quality of Life Questionnaire
The purpose of this retrospective chart review pilot study is to research the results and scores of the QOL questionnaire implemented across Allina Health clinics.
- Conditions
- Medical Oncology, Cardiology, Integrative Medicine, Physical and Rehabilitation Medicine
- Trial name
- NCT02906423
- Testing
- PROMIS-10 questionnaire
- Where
- United States
- Volunteers
- 43,000 people, healthy volunteers welcome
- Sponsor
- Allina Health System
Hepatic Neoplasm Malignant
Oxaliplatin and Capecitabine on Top of Sorafenib Versus Sorafenib Alone in Advanced Hepatocellular Carcinoma Patients
Primary Objective: To evaluate the efficacy of SECOX regimen by adding oxaliplatin plus capecitabine to sorafenib versus sorafenib alone as palliative treatment for unresectable HCC patients to prolong overall survival (OS) for…
- Trial name
- SECOX (NCT01245582)
- Testing
- oxaliplatin (SR96669), capecitabine, sorafenib
- Sponsor
- Sanofi
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