Clinical trials: Palliative Cancer
Palliative Care, Advanced Cancer
A Feasibility Study of Death Education Intervention for Family Caregivers of Advanced Cancer Patients
Advanced cancer is the leading cause of death in the world and China. Family caregivers, as the closest individuals to advanced cancer patients, suffer from a range of psychological and spiritual issues due to patients' impending…
- Conditions
- Palliative Care, Advanced Cancer, Family Caregivers
- Trial name
- NCT07367984
- Testing
- Death education intervention for family caregivers of advanced cancer patients
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Glioblastoma, Malignant Glioma
Early Integration of Palliative Care Using the BEACON PROQOL in Patients With High Grade Glioma and Their Caregivers
This trial assesses the quality of life in patients with high grade glioma and their caregivers using a questionnaire called the Beacon Patient Related Outcomes Quality of Life (PROQOL).
- Conditions
- Glioblastoma, Malignant Glioma, WHO Grade III Glioma
- Trial name
- NCT04630379
- Testing
- Palliative Therapy, Quality-of-Life Assessment, Supportive Care
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Mayo Clinic
Cancer
Prognosis and Survival Estimates in Palliative Therapy
The accuracy of clinical survival estimates is tested in comparison to objective prognostic scores.
- Trial name
- NCT00871520
- Testing
- no specific interventions
- Where
- 3 sites in Germany
- Volunteers
- 612 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Quality of Life
Pilot Study of Living With Hope Program
Hope is important to palliative home care patients. Our research team has developed a Living with Hope Program that has been found to increase hope and quality of life in older persons with advanced cancer.
- Trial name
- NCT01697982
- Testing
- Living with Hope Program, LWH film
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- University of Alberta
Cancer
Integrated Short-Term Palliative Rehabilitation in Incurable Cancer
The goal of this intervention trial is to determine if palliative rehabilitation in addition to usual care is more effective than usual care at improving health-related quality of life in patients with incurable solid cancer.
- Trial name
- INSPIRE (NCT05984797)
- Testing
- Integrated Short-term Palliative Rehabilitation
- Where
- 11 sites in Denmark, France and 3 more
- Volunteers
- 340 people
- Sponsor
- King's College London
Bladder Cancer
Quality of Life and Symptom Management in Patients With Bladder Cancer
RATIONALE: Learning about quality of life and symptom management in patients with bladder cancer may help doctors learn about the effects of treatment and plan the best treatment.
- Trial name
- NCT00772018
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- David Latini
Sarcoma
NY-ESO-1-Specific T-cells in Treating Patients With Advanced NY-ESO-1-Expressing Sarcomas Receiving Palliative Radiation Therapy
This pilot, phase I trial studies the safety of cancer-testis antigen (NY-ESO-1)-specific T cells (a type of immune cell) in treating patients with NY-ESO-1-expressing sarcomas that have spread to other places in the body and are…
- Trial name
- NCT02319824
- Testing
- Autologous NY-ESO-1-specific CD8-positive T Lymphocytes, Laboratory Biomarker Analysis, Palliative Radiation Therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Fred Hutchinson Cancer Center
Bone Metastases, Multiple Myeloma
ExAblate (MRgFUS) Treatment of Metastatic Bone Tumors for the Palliation of Pain
A Pivotal Study to Evaluate the Effectiveness and Safety of ExAblate Treatment of Metastatic Bone and Multiple Myeloma Tumors for the Palliation of Pain in Patients Who are not Candidates for Radiation Therapy
- Trial name
- NCT00656305
- Testing
- ExAblate MRfFUS
- Where
- 14 sites in United States, Canada and 3 more
- Volunteers
- 147 people
- Sponsor
- InSightec
Advanced Breast Cancer, Advanced Prostate Cancer
Engage Psychosocial Intervention for Cancer Symptoms
The goal of this clinical trial is to test the efficacy a new psychosocial symptom management intervention called ENGAGE for patients with Stage IV breast, prostate, lung, or colorectal cancer.
- Conditions
- Advanced Breast Cancer, Advanced Prostate Cancer, Advanced Lung Cancer, Advanced Colorectal Carcinoma
- Trial name
- Engage (NCT06555588)
- Testing
- ENGAGE, Supportive Care
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- Duke University
Advanced Cancer
A Structured Early Palliative Care Intervention for Patients With Advanced Cancer - a Randomized Controlled Trial With a Nested Qualitative Study (SENS Trial)
It is assumed that an early palliative care structured by SENS (a systematic, problem-based assessment system) in addition to standard oncology care compared with standard oncology care alone relieves distress in patients with…
- Trial name
- SENS (NCT01983956)
- Testing
- SENS model
- Where
- 3 sites in Switzerland
- Volunteers
- 150 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Breast Cancer
Monalizumab and Trastuzumab In Metastatic HER2-pOSitive breAst Cancer: MIMOSA-trial
In this phase II clinical trial the efficacy of the combination of monalizumab and trastuzumab is assessed in patients with metastatic or locally incurable HER2-positive breast cancer
- Trial name
- MIMOSA (NCT04307329)
- Testing
- Monalizumab, Trastuzumab
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- The Netherlands Cancer Institute
Breast Cancer Female
Telenursing and Breast Cancer: The Turkish Case
This study aims to determine the effectiveness of telenursing services on chemotherapy symptoms and comfort levels in patients with breast cancer in Turkey.
- Trial name
- NCT04480229
- Testing
- Telenursing and Counseling
- Volunteers
- 96 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Pelvic Cancer, Radiotherapy
Vorinostat and Palliative Radiotherapy
Phase I study. Side-effects when combined with standard palliative radiotherapy.
- Trial name
- PRAVO (NCT00455351)
- Testing
- Vorinostat
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
Palliative Care
Improvement of Support to Caregivers of Cancer Patients in Basic Palliative Care at Home
The aim of the project is to evaluate the use of the caregiver-led 'CSNAT intervention' to identify, prioritize and address support needs among caregivers of cancer patients who are starting in basic palliative care at home in…
- Trial name
- PiH (NCT03548012)
- Testing
- The Carer Support Needs Assessment Tool (CSNAT) intervention
- Where
- 10 sites in Denmark
- Volunteers
- 135 people
- Sponsor
- Bispebjerg Hospital
Cancer Pain, Pain
Evaluation of ESMO Guidelines Applicability and Adherence in Cancer Pain Management in the Palliative Care Setting
Palliative care (PC) is focused on improving the Quality of Life (QoL) of patients living with a life-threatening illness. Each year, an estimated 40 million people need PC management in the world.
- Conditions
- Cancer Pain, Pain, Cancer
- Trial name
- NCT04795739
- Where
- 8 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Antea Foundation
Advanced Cancer, Metastatic Disease
Symptom Trajectory Approaches to Research
The goal of this observational study is to understand how cancer makes children feel over time. The main things the researchers hope to learn are: When and how often do children have different feelings or sickness; Why do these…
- Conditions
- Advanced Cancer, Metastatic Disease, Cancer Treatment, Progressive Disease
- Trial name
- STAR (NCT07804875)
- Testing
- Health surveys
- Where
- 5 sites in United States
- Volunteers
- 228 people
- Sponsor
- University of Wisconsin, Madison
Leukemia, Childhood, Solid Tumor, Childhood
Observational MyPal-Child Study on the ePRO-based Early Palliative Care Digital System in Paediatric Oncology Patients
The main aim of the study is the evaluation of the feasibility of comprehensive service which has been developed while considering patient-orientated needs.
- Trial name
- MyPal4Kids (NCT04381221)
- Where
- 3 sites in Czechia, Germany
- Volunteers
- 100 people
- Sponsor
- Centre for Research and Technology Hellas
HER2 Negative Gastric Cancer
Comparison of Efficacy and Frequency of Adverse Events of 1st Line Palliative Chemotherapy EOX and mDCF Regimens in Advanced HER2-negative Gastric Carcinoma
The purpose of the study is to compare efficacy and safety of palliative chemotherapy EOX and mDCF regimens in the first-line treatment of patients with advanced HER2-negative gastric and gastroesophageal junction (GEJ)…
- Trial name
- NCT02445209
- Testing
- EOX, mDCF
- Volunteers
- 56 people
- Sponsor
- Jagiellonian University
Hematopoietic and Lymphoid Cell Neoplasm, Locally Advanced Malignant Solid Neoplasm
Assessment of Verbal Comprehension and Cognitive Processes in Patients Admitted to the Palliative and Supportive Care Unit
This study investigates the use electroencephalography (EEG - a test that measures brain waves) to learn if patients who appear unresponsive (do not respond to noises, words, or touch) retain any consciousness.
- Conditions
- Hematopoietic and Lymphoid Cell Neoplasm, Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm
- Trial name
- NCT05091632
- Testing
- Electroencephalography, Questionnaire Administration
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Palliative Medicine, Pediatric ALL
Paediatric Palliative Care Pain Management in the Community
To describe the the barriers and facilitators experienced by carers and healthcare professionals when managing medicines for pain relief for infants, children, and young people approaching the end of life in out of hospital…
- Trial name
- PARAMOUNT (NCT04519632)
- Testing
- Qualitative study
- Where
- United Kingdom
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Southampton
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