Clinical trials: Palliative Cancer
Nausea, Vomiting
Protreat-Trial: Prophylactic Antiemetic Treatment of Opioid-induced Nausea and Vomiting (OINV) in Palliative Care
Palliative cancer patients with tumor pain often suffer from nausea and vomiting when starting pain therapy with opioids. The objective of the clinical pilot trial is to evaluate the efficacy and tolerability of palonosetron in…
- Conditions
- Nausea, Vomiting, Pain, Advanced Cancer
- Trial name
- ProTreat (NCT05315999)
- Testing
- Palonosetron Hydrochloride
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Gerhild Becker
Caregiver, Psychological Impact of Cancer and Its Treatment
Palliative Care Intervention in Improving Symptom Control and Quality of Life in Patients With Stage II-IV Non-small Cell Lung Cancer and Their Family Caregivers
This clinical trial studies a palliative care intervention in improving symptom control and quality of life in patients with stage II-IV non-small cell lung cancer and their family caregivers.
- Conditions
- Caregiver, Psychological Impact of Cancer and Its Treatment, Recurrent Non-small Cell Lung Cancer, Stage IIA Non-small Cell Lung Cancer
- Trial name
- NCT02243748
- Testing
- Palliative Therapy, quality-of-life assessment, questionnaire administration
- Where
- 5 sites in United States
- Volunteers
- 361 people
- Sponsor
- City of Hope Medical Center
Anxiety, Nausea
Outpatient Oncology Aromatherapy for Symptom Management
The purpose of this research study is to determine whether using aromatherapy during chemotherapy infusion treatments in the outpatient Oncology setting promote relief of nausea and anxiety. The objectives of this study are: 1.
- Trial name
- NCT04449315
- Testing
- Young Living Lavender Essential Oil
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Central DuPage Hospital
Cancer Induced Bone Pain, Secondary Malignant Neoplasm of Bone
Thermal Testing in Bone Pain (TiBoP)
If cancer spreads to bones it can be very painful, especially when trying to move around. One of the best treatments is radiotherapy, which has to be given in a cancer centre.
- Conditions
- Cancer Induced Bone Pain, Secondary Malignant Neoplasm of Bone, Toxicity Due to Radiotherapy, Pain
- Trial name
- TiBoP (NCT02887833)
- Testing
- Clinical biomarker (thermal sensory testing)
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- University of Edinburgh
Cachexia, Cancer
Effectiveness of Nutritional Counselling and "Improved Atta" Supplementation in Cachexic Adult Indian Cancer Patients
Investigators are evaluating the nutritional role of IAtta supplementation along with nutritional counselling in delaying the progression of cachexia to refractory cachexia in adult cancer Indian patients.
- Trial name
- NCT02561143
- Testing
- Improved Atta, Wheat flour, Physical activity counseling
- Where
- 2 sites in India, United Kingdom
- Volunteers
- 150 people
- Sponsor
- University of Westminster
Lung Cancer, Nonsmall Cell, Lung Cancer
Palliative Thoracic ImmunoRT
The trial is designed as a prospective observational single arm study investigating stage IV non-small cell lung cancer patients who are routinely treated with a PD-1 inhibitor for indications approved by Health Canada.
- Trial name
- NCT03705806
- Testing
- Radiation combined with immunotherapy
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University Health Network, Toronto
Literacy, Bowel Symptoms
Effectiveness of Experiential Learning on Dietary Fiber Literacy
Acute symptom onset is the most common problem in colorectal cancer surgery, and it is also the source of the most painful impact on patients' lives.
- Trial name
- NCT04642417
- Testing
- dietary fiber literacy, routine care
- Where
- Taiwan
- Volunteers
- 66 people
- Sponsor
- National Taiwan University Hospital
Cancer, Cancer Cachexia
Effects of WB-EMS and Specific Dietary Supplements on Cancer Patients
Patients suffering from cancer often experience a loss of muscle mass and strength during disease and its therapy. Muscle wasting is the main characteristic of the so-called cancer cachexia syndrome and responsible for many…
- Conditions
- Cancer, Cancer Cachexia, Weight Loss, Muscle Loss
- Trial name
- NCT03151291
- Testing
- β-hydroxy-β-methylbutyrate (HMB), L-carnitine (LC), Eicosapentaenoic acid (EPA)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Non Small Cell Lung Carcinoma
Chemoradiotherapy in Patients With Localised Lung Cancer
The study compares 2 different methods of combined chemotherapy and radiotherapy for the treatment of localised lung cancer in patients not suitable for surgery. Hypothesis(es) to be tested: 1.
- Trial name
- NCT00193921
- Testing
- Vinorelbine, High dose Radiotherapy, Gemcitabine
- Where
- 8 sites in Australia
- Volunteers
- 82 people
- Sponsor
- Trans Tasman Radiation Oncology Group
Other Cancer, Gastrointestinal Cancer
Symptom Management Implementation of Patient Reported Outcomes in Oncology
Deficits in the management of common symptoms cause substantial morbidity for cancer patients.Because the health care delivery system is structured to be reactive and not proactive, there are missed opportunities to optimize…
- Conditions
- Other Cancer, Gastrointestinal Cancer, Thoracic Cancer, Gynecologic Cancer
- Trial name
- SIMPRO (NCT03850912)
- Testing
- Stakeholder Survey (Control Period), Stakeholder Survey (Intervention Period), Qualitative Interview
- Where
- 6 sites in United States
- Volunteers
- 42,808 people
- Sponsor
- Dana-Farber Cancer Institute
Glioblastoma
Easing Psychosocial Burden for Informal Caregivers
The overall goal of this study is to determine the best time to offer Meaning-Centered Psychotherapy (MCP), an intervention that has proven to be helpful in improving spiritual well-being and decreasing existential distress among…
- Trial name
- NCT03454295
- Testing
- Focus Group, Meaning-Centered Psychotherapy for Cancer Caregivers / MCP-C, Enhanced Usual Care / EUC
- Where
- 3 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Metastatic Cancer, Palliatives Treatments
Towards an Early Integration of Palliative Care in Oncology
The primary objective of the study is to describe the nature and to estimate the prevalence the health needs of patients with metastatic cancer and their main caregivers, between the period from diagnosis to death.
- Trial name
- BESACE (NCT05339945)
- Where
- France
- Volunteers
- 361 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Caregiver, Malignant Pleural Neoplasm
Embedded Palliative Care in Managing Symptoms in Participants With Recurrent Stage III-IV Thoracic Malignancies and Their Caregivers
This trial studies how well embedded palliative care works in managing symptoms in participants with stage III-IV thoracic malignancies that has come back and their caregivers.
- Conditions
- Caregiver, Malignant Pleural Neoplasm, Metastatic Thymic Carcinoma, Recurrent Lung Carcinoma
- Trial name
- NCT04662645
- Testing
- Palliative Therapy, Questionnaire Administration
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Tumor Size Greater Than or Equal to 5 cm
Efficacy and Toxicity of SCART
This study is expected to enroll patients for a period of five years, with a total of 30 participants. It is a prospective observational study involving cancer patients with tumors having a longest diameter greater than or equal…
- Trial name
- NCT06341257
- Testing
- Stereotactic Central/Core Ablative Radiation Therapy (SCART)
- Where
- Taiwan
- Sponsor
- Taichung Veterans General Hospital
Platelet Transfusion, Palliative Care
Retrospective Descriptive Study of Platelet Transfusion in Patients With Palliative Hematologic Malignancies at the University Hospital of Besançon
Development of palliative care is less effective for patients with hematologic malignancies. Limited data is available for end of life care in this population, moreover with thrombocytopenic patients.
- Trial name
- NCT03814486
- Testing
- descriptive
- Where
- France
- Volunteers
- 119 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Metastatic Breast Cancer
A Multicentre Phase I-II Study to Investigate the Combination of Bendamustine With Weekly Paclitaxel as First or Second Line Therapy in Patients With Metastatic Breast Cancer
The aim of the study is to establish a feasible combination of bendamustine and paclitaxel in a weekly schedule. The two agents have different toxicity profiles and are well tolerated when given in a weekly fashion.
- Trial name
- RiTa (NCT00661739)
- Testing
- Bendamustine
- Volunteers
- 38 people
- Sponsor
- GBG Forschungs GmbH
Neurocognitive Deficit, Quality of Life
WHOle Brain Irradiation or STEreotactic Radiosurgery for Five or More Brain Metastases (WHOBI-STER)
This work aims to evaluate neurocognitive performance, daily activity and quality of life and local control among patients with brain metastasis (MBM) ≥ 5 due to solid tumors treated with Stereotactic RadioSurgery (SRS) or Whole…
- Conditions
- Neurocognitive Deficit, Quality of Life, Activities of Daily Living
- Trial name
- WHOBI-STER (NCT04891471)
- Testing
- Stereotactic RadioTherapy, Whole Brain Irradiation
- Where
- 4 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Mediterranean Institute of Oncology
Breast Cancer, Bone Metastasis
Chemoradiation for Bone Metastasis
Pain from bone metastases of breast cancer origin is treated with localized radiation. Modulating doses and schedules has shown little efficacy in improving results.
- Conditions
- Breast Cancer, Bone Metastasis, Pain
- Trial name
- NCT01784393
- Testing
- chemoradiation
- Where
- Israel
- Volunteers
- 29 people
- Sponsor
- Rabin Medical Center
Cancer (Active Cancer, Meaning Not Being Cancer Free), of Any Stage and Involving Any Treatment/Care Regimen; i.e. Curative, Life-extending, or Palliative, Cancer (Solid Tumors)
WellSpan-THRIVE Cancer QOL Study
Cancer affects millions of people worldwide and can significantly impact not only survival, but also day-to-day quality of life.
- Conditions
- Cancer (Active Cancer, Meaning Not Being Cancer Free), of Any Stage and Involving Any Treatment/Care Regimen; i.e. Curative, Life-extending, or Palliative, Cancer (Solid Tumors), Cancer (With or Without Metastasis), Cancer - Ovarian
- Trial name
- THRIVE (NCT07433660)
- Where
- 5 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- WellSpan Health
Nausea, Vomiting and Anxiety Associated With Medical Oncology Patients
The Use of Aromatherapy for Symptom Management
The purpose of this pilot study is to introduce the use of aromatherapy/essential oils to medical oncology patients at Central DuPage Hospital to assess their perceived effectiveness to relieve symptoms of nausea or vomiting…
- Trial name
- NCT02163369
- Testing
- Peppermint and Lavender Essential Oils
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Central DuPage Hospital
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