Clinical trials: Palliative Cancer
Pelvic Cancer, Radiotherapy
Vorinostat and Palliative Radiotherapy
Phase I study. Side-effects when combined with standard palliative radiotherapy.
- Trial name
- PRAVO (NCT00455351)
- Testing
- Vorinostat
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
Cancer
Evaluation of Multidisciplinary Palliative Care on Terminal Cancer Patients in Taiwan
The purpose of the study is to compare the quality of dying and death of terminal cancer patients from the perspectives of medical staff and main care giver (family). The hypothesis is that their view points will be different.
- Trial name
- NCT01103700
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Cancer, Metastatic Cancer
Lattice Radiotherapy for Dose-Escalated Palliation of Bulky Tumors
The purpose of this research study is to determine if lattice radiation therapy (LRT) will provide better treatment for bulky (large) tumors than current standard of care radiotherapy.
- Conditions
- Cancer, Metastatic Cancer, Locally Advanced, Locally Advanced Solid Tumor
- Trial name
- NCT06416007
- Testing
- Lattice therapy (LRT)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Cincinnati
Dyspnea, Respiratory Insufficiency
Cognitive and Behavioral Intervention for the Management of Episodic Breathlessness in Patients With Advanced Disease
Episodic breathlessness is a common and distressing symptom in patients with advanced disease such as cancer, chronic obstructive pulmonary disease (COPD) and chronic heart failure.
- Conditions
- Dyspnea, Respiratory Insufficiency, Neoplasms, Pulmonary Disease, Chronic Obstructive
- Trial name
- CoBeMEB (NCT04630743)
- Testing
- Cognitive and Behavioral intervention for the Management of Episodic Breathlessness
- Where
- Germany
- Volunteers
- 49 people
- Sponsor
- University of Cologne
Quality of Life, Infection
Impact of AferBio® on Quality of Life and Chemotherapy Toxicity in Lung Cancer Patients
The AFERBIO study will evaluates safety and potential benefit of AferBio® in patients with non-small cell lung cancer undergoing at least a second-line palliative monochemotherapy.
- Conditions
- Quality of Life, Infection, Drug Toxicity
- Trial name
- AFERBIO (NCT03469063)
- Testing
- AferBio
- Where
- Brazil
- Volunteers
- 104 people
- Sponsor
- Barretos Cancer Hospital
Gastric Cancer (GC), Immunotherapy
Developing and Testing the Effectiveness of Smart Healthcare Assisted Individualized Symptom Management Education and Home-based Exercise on Frailty, Treatment-related Adverse Events and Quality of Life in Advanced Gastric Cancer Patients Receiving Immunotherapy
The goal of this randomized controlled intervention is to develop and evaluate the effectiveness of the nurse-led with AI chatbot Individualized Symptom Management Education and Home-based Exercise (AI-ISME\&HE) based on The…
- Trial name
- NCT07732543
- Testing
- AI-ISME&HE
- Volunteers
- 110 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Nursing Caries, Pain
Effect of Music on Pain in Cancer Patients in Palliative Care Service: a Randomized Controlled Study
Background: Palliative care services can be applied in chronic, life-threatening conditions such as cancer, and provide physical, mental and psychological support to patients worldwide.
- Conditions
- Nursing Caries, Pain, Music Therapy
- Trial name
- nursingcare (NCT04486443)
- Testing
- music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- gönül düzgün
Multiple Myeloma
Individualized Education for Bortezomib-Related Symptom Management in Multiple Myeloma
This study evaluated an individualized, nurse-delivered education program for managing treatment-related symptoms in patients with newly diagnosed multiple myeloma receiving bortezomib for the first time.
- Trial name
- NCT07774988
- Testing
- Individualized Nurse-Delivered Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Can Lafci
Advanced Cancer
Balance, Activity and Quality of Life
Background: Advanced cancer may cause functional limitations, subsequently leading to decreased ability to perform and engage in everyday activities, such as self-care, household, leisure and civic life.
- Trial name
- BAL (NCT04772690)
- Testing
- A resource-oriented intervention
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- REHPA, The Danish Knowledge Centre for Rehabilitation and Palliative Care
Metastatic Colo-rectal Cancer
LOTCOL Study: Local Treatment of Colo-rectal Liver Met
In this study the investigators will include colo-rectal cancer (CRC) patients starting last line of standard palliative chemotherapy.
- Trial name
- LOTCOL (NCT01867918)
- Testing
- Radiofrequency ablation, microwave, radiation therapy, Standard Chemotherapy
- Where
- Norway
- Volunteers
- 3 people
- Sponsor
- Oslo University Hospital
Cancer, Palliative Radiotherapy
Palliative Lattice Stereotactic Body Radiotherapy (SBRT)
Standard palliative radiotherapy regimens may provide limited durability of response in large tumors. Thus, there is a clinical need for a new approach.
- Trial name
- NCT04133415
- Testing
- Lattice stereotactic body radiation therapy, Peripheral blood
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Washington University School of Medicine
Secondary Bone Cancer, Bone Metastases
MRgFUS Versus EBRT in Patients With Metastatic Non-spinal Bone Disease
The objective of this trial is to collect and compare safety and effectiveness data of Magnetic Resonance guided Focused Ultrasound (MRgFUS) using the ExAblate 2100 device and radiotherapy in the treatment of metastatic bone…
- Trial name
- NCT03404362
- Testing
- Bone Metastases Pain treatment
- Where
- 2 sites in Italy
- Volunteers
- 198 people
- Sponsor
- University of Roma La Sapienza
Secondary Malignant Neoplasm of Bone
Pilot Study for Palliation of Pain in Bone Metastases by MR-HIFU
This study is to confirm the safety and technical of MRI guided High Intensity Focused Ultrasound (HIFU) for Palliation for Pain of Skeletal Metastases.
- Trial name
- NCT01117246
- Testing
- High Intensity Focused Ultrasound
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Philips Healthcare
HIV Infections, Cancer
A Multicenter Phase II/III, Placebo-Controlled Study of SNX-111 Administered Intrathecally to Cancer and AIDS Patients With Chronic Pain
To determine the safety and efficacy of SNX-111 in controlling severe, chronic pain in cancer and AIDS patients.
- Conditions
- HIV Infections, Cancer, Pain
- Trial name
- NCT00002160
- Testing
- Ziconotide
- Where
- 44 sites in United States
- Volunteers
- 100 people
- Sponsor
- Neurex
Cancer
Improving Adherence to ACS Guidelines on Nutrition and Physical Activity in Latinas With Cancer and Their Informal Caregivers
This research study is testing the feasibility and acceptability of a 12-week intervention that integrates telephone coaching and printed materials about the ACS guidelines and healthy lifestyle behaviors in order to manage…
- Trial name
- NCT04314479
- Testing
- Symptom Assessment and Health Coaching
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Arizona
Pain, Pancreatic Cancer
Safety and Efficacy of Cryoablation for Abdominal Pain Associated With Pancreatic Cancer
CUC10-PAN09 will evaluate the safety and efficacy of cryoablation therapy on the relief of epigastric/abdominal pain associated with pancreatic cancer.
- Trial name
- NCT01335945
- Testing
- Cryoablation
- Where
- 3 sites in United States
- Volunteers
- 14 people
- Sponsor
- Boston Scientific Corporation
Breast Neoplasms
Behavioral Symptom Management Program for Breast Cancer in Singapore and The US
Research indicates that up to two-thirds of patients with advanced cancer experience significant symptom burden (e.g., anxiety and depression, pain, fatigue), yet these symptoms are not adequately addressed.
- Trial name
- NCT02865148
- Testing
- Cognitive behavioral therapy
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Duke-NUS Graduate Medical School
Breast Cancer
TBP Study With Capecitabine Plus Minus Trastuzumab
This study is done in patients having Breast Cancer with metastasis (patients with positive receptor HER2) whose disease progressed after receiving Trastuzumab.
- Trial name
- NCT00148876
- Testing
- Capecitabine, Trastuzumab
- Where
- Germany
- Volunteers
- 482 people
- Sponsor
- GBG Forschungs GmbH
Malignant Bowel Obstruction
Palliative Management of Inoperable Malignant Bowel Obstruction
To identify the role of palliative medical management of inoperable malignant bowel obstruction (MBO) with Octreotide, Dexamethasone and Metoclopramide given together as triple therapy.
- Trial name
- NCT04027348
- Testing
- Dexamethasone, Metoclopramide, Octreotide
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Roswell Park Cancer Institute
Esophageal Cancer
Chemoradiotherapy for Advanced Esophageal Cancer
This study aims to show that the addition of carboplatin and paclitaxel chemotherapy to a palliative course of external beam radiation treatment improves both dysphagia relief and patient quality of life in patients with…
- Trial name
- PaRCUS (NCT02297217)
- Testing
- Carboplatin and Taxol (paclitaxel), External Beam Radiation
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- AHS Cancer Control Alberta
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