Clinical trials: Palliative Cancer
Cancer, Quality of Life
Financial Distress in Patients With Advanced Cancer
Advanced cancer has an adverse effect in virtually all dimensions of patients' lives (physical, psychosocial, spiritual, familial, role function).
- Trial name
- DIFIC (NCT01868100)
- Testing
- self-completion questionnaire
- Where
- France
- Volunteers
- 144 people
- Sponsor
- Hospices Civils de Lyon
Music Therapy, Palliative Care
Evaluation of the Effectiveness of Music Therapy on Anxiety Levels in Patients With Advanced Cancer Hospitalized in a Palliative Care Unit
A music therapy intervention can be either receptive or active. In both cases, somatic effects have been observed, with a direct impact on respiratory, cardiac and hemodynamic parameters, as well as psychological effects…
- Conditions
- Music Therapy, Palliative Care, Cancer, Anxiety
- Trial name
- CessataEl'ansi (NCT07806435)
- Testing
- depression management, Kigonki, questionnaire
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Esophagus Cancer
TTS Esophageal HILZO Stent: A Safety and Feasibility Study
A multicenter non-randomized prospective clinical study assessing the safety and feasibility of the esophageal through-the-scope HILZO Covered self-expandable metal stent placement for palliation of malignant dysphagia
- Trial name
- HILZO (NCT03269903)
- Testing
- HILZO esophageal stent
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Radboud University Medical Center
Prostate Cancer
Effects of an Interactive ICT-Platform for Assessment and Management of Symptoms in Patients Treated for Prostate Cancer
The purpose of this study is to evaluate the effects of an interactive ICT-platform for use in a smartphone or tablet in patients treated with radiotherapy for prostate cancer.
- Trial name
- PhONEME (NCT02477137)
- Testing
- smartphone or tablet
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Karolinska Institutet
Neoplasm Metastasis, Pain
Virtual Reality for Advanced Cancer Pain
Background Pain is commonly experienced by people who are living with advanced (incurable) cancer. There is evidence to suggest virtual reality could help to relieve this pain: however, this evidence is poor quality with the…
- Conditions
- Neoplasm Metastasis, Pain, Palliative Care
- Trial name
- VRcan (NCT06534580)
- Testing
- Virtual Reality
- Where
- 4 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- University College, London
Cancer
Using SMART Design to Improve Symptom Management Strategies Among Cancer Patients
The purpose of this study is to compare reflexology to meditative practices to reduce symptoms in cancer patients.
- Trial name
- NCT02759146
- Testing
- Reflexology, Meditative Practices
- Where
- 7 sites in United States
- Volunteers
- 347 people
- Sponsor
- Michigan State University
Palliative Care, Advanced Cancer
Coaching in Palliative Surgical Oncology
This study aims to evaluate the effectiveness of a serious illness coaching intervention (CONCORD) in improving quality of serious illness conversation (SIC), treatment decision-making, goal-concordant care delivery and quality…
- Trial name
- NCT07789093
- Testing
- CONCORD coaching intervention
- Where
- Singapore
- Volunteers
- 220 people
- Sponsor
- Singapore General Hospital
Advanced Solid Tumors, Advanced Solid Tumors Cancer
ET-SPACE Whole-Body Infrared Hyperthermia in Patients With Advanced Solid Tumors
This ambispective observational cohort study will evaluate biological changes, palliative outcomes, and safety associated with ET-SPACE whole-body infrared hyperthermia in patients with advanced solid tumors.
- Trial name
- HEAIS-009 (NCT07793214)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Zhejiang Hospital
GVHD, Chronic, Hematological Malignancy
Systematic Symptom Identification With Disease Specific PROM to Assess Symptoms of Chronic GVHD in Outpatient Care in Patients Post HSCT
A two sited feasibility study to test the feasibility of systematic symptom identification with disease specific and clinically developed PROM (Lee Symptom Scale) longitudinally with a 12 month follow up in outpatient care in…
- Trial name
- SIMPly-CARE (NCT04884204)
- Testing
- Lee Symptom Scala
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pelvic Cancer, Radiotherapy
Short Course Radiation Therapy in Palliative Treatment of Pelvic Cancer
Aim of the study is to assess efficacy of a short course radiation treatment in patients with symptomatic pelvic malignant lesions
- Conditions
- Pelvic Cancer, Radiotherapy, Palliative Care
- Trial name
- NCT03804333
- Testing
- standard treatment, short course treatment
- Where
- Italy
- Volunteers
- 54 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Colorectal Cancer, Bladder Cancer
Effects of a Neuroscience-based Technique on Cancer Patients Announced of a Palliative Disease Progression and Partners
The diagnosis and treatment trajectory of cancer can constitute a traumatic event because these can be perceived as sudden, catastrophic and life threatening.
- Conditions
- Colorectal Cancer, Bladder Cancer, Prostate Cancer, Kidney Cancer
- Trial name
- NeuroPrevPTSD (NCT03652298)
- Testing
- Memory structuring intervention + Vagal breathing, support and attention (usual care)
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Centre Oscar Lambret
Colorectal Cancer Metastatic
Effectiveness Study of Resection of Primary Tumor in Stage IV Colorectal Cancer Patients
There is still no perfect treatment suggestion for patients with asymptomatic colorectal cancer with unresectable metastatic disease.
- Trial name
- NCT02149784
- Testing
- Surgical resection of primary tumor
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Sun Yat-sen University
Medical Oncology, Palliative Care
Improvement of Quality of Life by Cannabinoids in Oncologic Patients
The goal is to explore whether the application of cannabis extract Avextra 10/10 solution is suitable to contribute to an improvement in the symptom burden and well-being of oncological palliative care patients.
- Conditions
- Medical Oncology, Palliative Care, Quality of Life, Cannabinoids
- Trial name
- BELCANTO (NCT06097533)
- Testing
- Cannabisextrakt Avextra 10/10 Lösung
- Where
- 3 sites in Germany
- Volunteers
- 79 people
- Sponsor
- University Hospital Schleswig-Holstein
Pain, Cancer
Improvement of Self Management for Oncologic Patients With Pain
This study will test the SCION (Self care improvement through oncology nursing)-PAIN program, a multi-modular structured intervention to improve self management in oncologic patients with pain compared to care as usual (standard…
- Trial name
- NCT00779597
- Testing
- SCION (Self care improvement through oncology nursing)-PAIN program
- Where
- 3 sites in Germany
- Volunteers
- 208 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Metastasis, Locally Advanced Solid Tumor
Trial of XRD-0394, a Kinase Inhibitor, in Combination With Palliative Radiotherapy in Advanced Cancer Patients
XRD-0394 is a novel, potent, oral, small molecule dual inhibitor of ataxia telangiectasia mutated kinase (ATM) and deoxyribonucleic acid (DNA)-dependent protein kinase (DNA-PK) that has selectivity compared with other…
- Conditions
- Metastasis, Locally Advanced Solid Tumor, Recurrent Cancer
- Trial name
- NCT05002140
- Testing
- XRD-0394, Palliative radiotherapy
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- XRad Therapeutics Inc
Breast Cancer Stage I, Colorectal Cancer
Mind-Body Interventions for the Improvement of Quality of Life, Stress, and Sleep Quality Among Survivors of Breast, Prostate, Endometrial, or Colorectal Cancer
This clinical trial studies how well mind-body interventions work in improving quality of life (QOL), stress, and sleep quality among survivors of breast, prostate, endometrial, or colorectal cancer.
- Trial name
- NCT07745023
- Testing
- Media Intervention, Mind-body intervention, Meditation Therapy
- Volunteers
- 30 people
- Sponsor
- Roswell Park Cancer Institute
Head and Neck Squamous Cell Carcinoma
Pembrolizumab, INCB081776, and Radiation Therapy for Head and Neck Squamous Cell Carcinoma
This study is evaluating INCB081776 when given in combination with the checkpoint inhibitor pembrolizumab and palliative radiation therapy in patients with metastatic or recurrent metastatic or recurrent head and neck squamous…
- Trial name
- NCT06308913
- Testing
- INCB081776, Pembrolizumab, Palliative RT
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Wisconsin, Madison
Colorectal Cancer
An mHealth Symptom Management Intervention for Colorectal Cancer Patients (mCOPE)
The investigators have developed an innovative mobile health (mHealth) coping skills training protocol, mCOPE, that is adapted to meet the multiple symptom needs and stage-of-life challenges faced by young and middle-aged adults…
- Trial name
- NCT04763174
- Testing
- mHealth Coping Skills Training for Symptom Management (mCOPE)
- Where
- 2 sites in United States
- Volunteers
- 167 people
- Sponsor
- Duke University
Neoplasm Metastases, Metastases, Neoplasm
Palliative Dose Escalated Radiation for Painful Non-Spine Bone Metastases and Painful Non-Bone Metas
The investigators hypothesize that with dose escalation to 40-50 Gy in ten fractions, the complete pain response rate at one month can be increased to 40-50% in painful non-spinal bone metastases.
- Trial name
- NCT05419518
- Testing
- EXTERNAL BEAM RADIATION
- Where
- 7 sites in United States
- Volunteers
- 124 people
- Sponsor
- Rutgers, The State University of New Jersey
Dementia, Chronic Disease
Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2)
The objective of this protocol is to test the effectiveness of a Jumpstart intervention on patient-centered outcomes for patients with chronic illness by ensuring that they receive care that is concordant with their goals over…
- Conditions
- Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasms
- Trial name
- PICSI-H (NCT04283994)
- Testing
- Survey-based Patient/Clinician Jumpstart, EHR-based Clinician Jumpstart
- Where
- 3 sites in United States
- Volunteers
- 756 people
- Sponsor
- University of Washington
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