Clinical trials: Palliative Cancer
Stem Cell Transplant
Inpatient Palliative Care for Patients Undergoing Hematopoietic Stem Cell Transplantation
This research study is evaluating the impact of early involvement of a palliative care team working with the transplant oncology team will have on the quality of life, symptoms, and mood of patients undergoing stem cell…
- Trial name
- NCT03641378
- Testing
- Palliative Care Intervention, Standard Transplant Care
- Where
- 3 sites in United States
- Volunteers
- 546 people
- Sponsor
- Massachusetts General Hospital
Pain, Nausea
Cannabis For Cancer-Related Symptoms
Clinical evidence is urgently needed to be able to advise patients on which cannabis-based products to take, or to avoid, in managing cancer-related symptoms.
- Conditions
- Pain, Nausea, Anxiety, Sleep Disturbance
- Trial name
- CAFCARS (NCT03948074)
- Testing
- Cannabis
- Where
- 8 sites in Canada
- Volunteers
- 91 people
- Sponsor
- Pippa Hawley
Colorectal Neoplasms
Study to Evaluate the Effects of Sorafenib if Combined With Chemotherapy (FOLFOX6 or FOLFIRI) in the Second-Line Treatment of Colorectal Cancer
The purpose of this study is to determine whether sorafenib in combination with chemotherapy has a positive effect on time to progression of the tumor or death for the treatment of large bowel cancer that has already progressed…
- Trial name
- FOSCO (NCT00889343)
- Testing
- Sorafenib, Oxaliplatin or Irinotecan, Leucovorin
- Where
- 57 sites in Germany
- Volunteers
- 101 people
- Sponsor
- AIO-Studien-gGmbH
Cancer, Heart Failure
Implementing Spiritual Care in Inpatient Palliative Care
The goal of this observational study is to is to ascertain the spiritual needs of palliative patients in a standardized manner using the Spiritual Needs Questionnaire and to promptly address those needs by (specialized) spiritual…
- Conditions
- Cancer, Heart Failure, Chronic Obstructive Pulmonary Disease, Lateral Sclerosis
- Trial name
- SCPC (NCT06206551)
- Testing
- Spiritual Needs Questionnaire
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Muenster
Child, Only, Cancer
Digital Storytelling in Symptom Management Pediatric Oncology
The aim of this clinical study is to evaluate the effectiveness of the digital storytelling method in symptom management in children diagnosed with oncology.
- Conditions
- Child, Only, Cancer, Symptoms and Signs, Narration
- Trial name
- NCT06436651
- Testing
- Digital Storytelling
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Kocaeli University
Metastatic Cancer
Stereotactic Radiosurgery in Treating Patients With Spinal Metastases
RATIONALE: Stereotactic radiosurgery can send x-rays directly to the tumor and cause less damage to normal tissue. It may also help patients with spinal metastases live more comfortably.
- Trial name
- NCT00853528
- Testing
- questionnaire administration, diffusion tensor imaging, functional magnetic resonance imaging
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Boston Medical Center
Anxiety, Pain
Music and VR Effects on Pain, Anxiety, and Fear During Oral Mucositis Care in Leukaemic Children
Children undergoing leukaemia treatment are exposed to a wide range of chemotherapeutic agents and immunosuppressive therapies during treatment and are therefore at great risk for complications.
- Conditions
- Anxiety, Pain, Fear
- Trial name
- NCT06955338
- Testing
- Music intervention, Virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ege University
Neoplasms, Pain
REST: Reducing End-of-Life Symptoms With Touch
The purpose of this study is to determine whether massage therapy is effective in reducing pain and distress and improving quality of life among cancer patients at life's end.
- Trial name
- NCT00065195
- Testing
- Moving touch therapy, Nonmoving touch therapy
- Where
- 9 sites in United States
- Volunteers
- 440 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Unspecified Adult Solid Tumor, Protocol Specific
Palliative Care Intervention in Improving Quality of Life, Psychological Distress, and Communication in Patients With Solid Tumors Receiving Treatment
This pilot randomized clinical trial studies palliative care intervention in improving quality of life, psychological distress, and communication in patients with solid tumors receiving treatment on phase I trials.
- Trial name
- NCT01828775
- Testing
- palliative care, quality-of-life assessment, survey administration
- Where
- 2 sites in United States
- Volunteers
- 480 people
- Sponsor
- City of Hope Medical Center
Glioblastoma, Recurrent Brain Neoplasm
Palliative 4pi Radiotherapy in Treating Patients With Recurrent Glioblastoma Multiforme
This pilot clinical trial studies the feasibility of palliative 4pi radiotherapy in treating patients with glioblastoma multiforme that has come back after standard chemoradiation.
- Trial name
- NCT02575027
- Testing
- Palliative Radiation Therapy, Questionnaire Administration, Radiation Therapy Treatment Planning and Simulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Cancer, Congenital Heart Disease
Supporting Patient Provider Communication in Paediatric Care
Children with Cancer or congenital heart disease (CHD) experience complex, physical, psychosocial and behavioural symptoms and problems due to the illness, treatment, and medical procedures.
- Trial name
- SiSom (NCT01280227)
- Testing
- SiSom
- Where
- Norway
- Volunteers
- 144 people
- Sponsor
- Oslo University Hospital
Platinum-resistant Ovarian Cancer, Recurrent Ovarian Cancer
H.O.P.E: Helping Ovarian Cancer Patients Cope
The purpose of this study is to test the effect of the gynecologic oncologists with palliative care specialist collaboration (GO-PC) intervention on patient quality of life.
- Conditions
- Platinum-resistant Ovarian Cancer, Recurrent Ovarian Cancer, Palliative Care
- Trial name
- NCT02090582
- Testing
- Structured Palliative Care, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- Duke University
Lung Cancer
Palliative 3-Dimensional Conformal Radiation Therapy in Reducing Radiation Side Effects in Patients With Lung Cancer. ICORG 06-34
RATIONALE: 3-dimensional conformal radiation therapy may lessen side effects caused by palliative radiation therapy and improve the quality of life of patients with lung cancer.
- Trial name
- NCT01176487
- Testing
- questionnaire administration, quality-of-life assessment, 3-dimensional conformal radiation therapy
- Where
- 2 sites in Ireland
- Volunteers
- 40 people
- Sponsor
- Cancer Trials Ireland
Renal Cell Carcinoma
Study of Sorafenib and Palliative Radiotherapy in Kidney Cancer That Spreads to the Bone
The purpose of this study is to investigate the use of a new anti-angiogenic drug called sorafenib, in combination with radiotherapy, for renal cell cancer that has spread to the bone and is causing significant pain.
- Trial name
- NCT00609934
- Testing
- Sorafenib, external beam radiotherapy
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University Health Network, Toronto
Advanced Cancer, End Stage Organ Failure
Emergency Medicine Palliative Care Access
This is a two-arm, multi-site randomized controlled trial of 1,350 older adults (50+ years) with either advanced cancer (defined as metastatic solid tumor) or poor prognosis end-stage organ failure (New York Heart Association…
- Trial name
- EMPallA (NCT03325985)
- Testing
- Nurse-led telephonic case management, Facilitated,outpatient specialty palliative care
- Where
- 18 sites in United States
- Volunteers
- 1,606 people
- Sponsor
- NYU Langone Health
Advanced Malignant Neoplasm, Caregiver
Preference of Room Setting and Waiting Time in Patients With Advanced, Locally Advanced, or Metastatic Cancer and Their Caregivers Who Are Seen in the Outpatient Supportive/Palliative Care Center
This trial studies the preference of room setting and waiting time in patients with cancer that has spread to nearby tissue or lymph nodes or other places in the body and their caregivers who are seen in the outpatient…
- Conditions
- Advanced Malignant Neoplasm, Caregiver, Locally Advanced Malignant Neoplasm, Metastatic Malignant Neoplasm
- Trial name
- NCT03671226
- Testing
- Questionnaire Administration
- Where
- United States
- Volunteers
- 406 people
- Sponsor
- M.D. Anderson Cancer Center
Cancer, Heart Failure
Improving Pharmacological Transition of Palliative Care Patients From Inpatient to Outpatient Care
The transition of palliative care patients from inpatient to outpatient care is aimed to be improved through structured pharmaceutical discharge management by a trained pharmacist.
- Conditions
- Cancer, Heart Failure, COPD
- Trial name
- EntMedPall (NCT06648733)
- Testing
- Structured pharmaceutical discharge management
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital Muenster
Older Patients, Colorectal Cancer
DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer
The goal of this phase III, open-label, non-inferiority randomized controlled clinical trial is compare upfront dose-reduced chemotherapy with the standard dose chemotherapy in older patients ( ≥70 years) with metastasized…
- Conditions
- Older Patients, Colorectal Cancer, Metastatic Cancer, Candidates for Palliative Chemotherapy
- Trial name
- DOSAGE (NCT06275958)
- Testing
- Doublet Chemotherapy, Standard Dose (100%), Doublet Chemotherapy, Dose-reduced (75%), Monotherapy, Standard Dose (100%)
- Where
- 36 sites in Netherlands
- Volunteers
- 587 people
- Sponsor
- Leiden University Medical Center
Advanced Cancer
Integration of Palliative Care in an Oncology and Hematology Unit
The main goal of this study is to assess retrospectively the integration of Palliative Care in an oncology and hematology unit. The investigators will study the last six month of life on advanced cancer patients and retrieve data…
- Trial name
- NCT04089306
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Symptoms and Signs, Cancer
Heuristic Tool To Improve Symptom Self-Management in Adolescents and Young Adults With Cancer
Determine the effects of the Computerized Symptom Assessment Tool (C-SCAT) versus usual care on the primary outcomes of self-efficacy for symptom management and symptom self-management behaviors
- Conditions
- Symptoms and Signs, Cancer, Childhood Cancer
- Trial name
- NCT05958316
- Testing
- Computerized Symptom Capture Tool (C-SCAT) Intervention, Usual Care Control
- Where
- 5 sites in United States
- Volunteers
- 126 people
- Sponsor
- Virginia Commonwealth University
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