Clinical trials: Palliative Cancer
Stage IV Lung Cancer
Shortened High-dose Palliative Radiotherapy for Lung Cancer
The SHiP-Rt Study aims to investigate the safety and efficacy of reducing the number of RT fractions and RT duration, compared to the current standard of care (36Gy in 12 fractions over 16 days), by using shortened…
- Trial name
- SHiP-Rt (NCT06483308)
- Testing
- Radiotherapy
- Where
- 4 sites in United Kingdom
- Volunteers
- 37 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Cannabis Use, Cancer
Cannabis Use Registry to Improve Overall Understanding of Symptoms (CURIOUS)
Through partnership with Ontracka, the HealthPartners Institute Cancer Research Center created a secure and compliant app-based technology with the ability to seamlessly collect patient-level data on symptoms, cannabis use…
- Trial name
- CURIOUS (NCT07227324)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Locally Advanced Malignant Neoplasm, Metastatic Malignant Neoplasm
Ride to Care - Quality of Life With Transportation for RT
This trial studies how well Uber health intervention works in eliminating transportation barriers for disadvantaged patients with cancer that has spread to nearby tissue, lymph nodes, or other places in the body, undergoing…
- Trial name
- NCT03849742
- Testing
- Quality-of-Life Assessment, Questionnaire Administration, Supportive Care
- Sponsor
- University of California, San Francisco
Head Neck Cancer, Squamous Cell Cancer of Head and Neck (SCCHN)
Stereotactic MRI-guided Focused Ultrasound Mesencephalotomy
This phase 1 multi-site study investigates the safety and initial effectiveness of focused ultrasound lesioning of the contralateral mesencephalon for severe, opioid-resistant pain associated with head and neck cancer and…
- Conditions
- Head Neck Cancer, Squamous Cell Cancer of Head and Neck (SCCHN), Cancer Pain
- Trial name
- MRg-FUS (NCT07405645)
- Testing
- ExAblate Neuro
- Where
- 6 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia
Cancer
Low Intensity Aerobic Exercise and Active Exercises in Cancer Patients Receiving Palliative Care
To compare the effect of low intensity aerobic exercise and active ROM exercises on cancer related fatigue and its associated symptoms and quality of life in cancer patients receiving palliative care.
- Trial name
- NCT05059990
- Testing
- Low Intensity Aerobic Exercises Group, Active Exercises Group
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Metastatic Malignant Female Reproductive System Neoplasm
Single Fraction or Multi-fraction Palliative Radiation Therapy for the Improvement of Quality of Life in Patients With Metastatic Gynecologic Cancers
This phase II trial studies if a single session of palliative radiation therapy can help improve symptoms of gynecologic cancers that have spread to other places in the body (metastatic) and that affect quality of life as well or…
- Trial name
- NCT04516135
- Testing
- 3-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, Quality-of-Life Assessment
- Where
- 3 sites in United States
- Volunteers
- 28 people
- Sponsor
- M.D. Anderson Cancer Center
Cancer Pain
A Novel mHealth Approach to Assess and Manage Palliative Care Needs for Cancer Patients in Kigali
Palliative care is an approach that improves the quality of life of patients and their families facing the problem associated with life-threatening illness such as cancer, through the prevention and relief of suffering by means…
- Trial name
- NCT03367637
- Testing
- Standard palliative care, Smart Phone based symptom evaluation application
- Where
- Rwanda
- Sponsor
- Massachusetts General Hospital
Hepatocellular Carcinoma
Liposomal Doxorubicin Plus Gemcitabine Versus Oxaliplatin Plus Fluorouracil/Leucovorin for Hepatocellular Carcinoma
The purpose of this study is to determine that Liposomal Doxorubicin(LD) plus Gemcitabine(GEM) is superior to Oxaliplatin（OXA） Plus Fluorouracil/Leucovorin(FOLFOX4) in prolonging progression-free survival（PFS） in patients with…
- Trial name
- LD-FOX4/HCC (NCT02527772)
- Testing
- Liposomal Doxorubicin+Gemcitabine, FOLFOX4
- Sponsor
- Guangxi Medical University
Locally Advanced Pancreatic Cancer, Metastatic Pancreatic Cancer
Gemcitabine, Oxaliplatin and Capecitabine for Advanced Pancreatic Carcinoma
Gemcitabine is the mainstay of palliative chemotherapy for patients with advanced pancreatic cancer (APC). Recent randomized trials have shown increased clinical benefit with the addition of oxaliplatin and prolonged median…
- Trial name
- GEMOXEL (NCT00744640)
- Testing
- gemcitabine, oxaliplatin, capecitabine
- Where
- 8 sites in Switzerland
- Volunteers
- 46 people
- Sponsor
- University Hospital, Basel, Switzerland
Gastro-esophageal Cancer
Feasibility and Effect of Resistance Training and Protein Supplementation in Patients With Advanced Gastroesophageal Cancer
Patients with advanced gastroesophageal cancer are in great risk of losing skeletal muscle mass and developing cancer cachexia. Low skeletal muscle mass has a negative impact on quality of life, impairs physical function…
- Trial name
- NCT05650827
- Testing
- Resistance training, Protein supplement
- Where
- Denmark
- Volunteers
- 54 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Digestive System Neoplasms
IP rmhTNF-NC + Tislelizumab + Palliat RT for GIT Tumor Malignant Ascites After Failed Std Tx
This study is a prospective, non-randomized, dual-cohort Phase II clinical trial designed to explore the efficacy and safety of radiotherapy combined with intraperitoneal injection of Recombinant Mutant Human Tumor Necrosis…
- Trial name
- NCT07196540
- Testing
- Radiotherapy for large-volume abdominal lesions + whole peritoneal cavity low-dose radiotherapy + rmhTNF-NC + tislelizumab
- Volunteers
- 78 people
- Sponsor
- Sun Yat-sen University
Malignant Mesothelioma
Palliative Therapy With or Without Chemotherapy in Treating Patients With Malignant Mesothelioma
RATIONALE: Palliative therapy may help patients with advanced cancer live more comfortably. It is not yet known if palliative therapy is more effective with or without chemotherapy in treating patients who have malignant…
- Trial name
- NCT00030459
- Testing
- cisplatin, mitomycin C, vinblastine sulfate
- Where
- 9 sites in United Kingdom
- Sponsor
- British Thoracic Society
Palliative Care
Randomized Controlled Trial of Group Psychotherapy Interventions for Cancer Patients
The purpose of this study is to compare two types of group counseling for cancer patients: Meaning-Centered counseling and Supportive counseling.
- Trial name
- NCT00494910
- Testing
- Meaning Centered Group Psychotherapy, Supportive Group Psychotherapy
- Where
- United States
- Volunteers
- 253 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cancer, Palliative Care
Music Therapy for Cancer Patients(Meraki_PC)
The overall aim of the study is to analyse the impact of a music therapy-based treatment on the emotional well-being and quality of life of cancer patients in palliative care (PC).
- Trial name
- Meraki_Cancer (NCT06345924)
- Testing
- MERAKI_PC
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- University of Valencia
Head and Neck Cancer
Photodynamic Therapy in Treating Patients With Recurrent, Refractory, or Second Primary Head and Neck Cancer That Cannot Be Treated With Surgery or Radiation Therapy
RATIONALE: Photodynamic therapy uses light and drugs that make cancer cells more sensitive to light to kill tumor cells. This may be an effective palliative treatment for head and neck cancer.
- Trial name
- NCT00003856
- Testing
- temoporfin
- Where
- 7 sites in United States
- Volunteers
- 75 people
- Sponsor
- Quintiles, Inc.
Gastric Cancer
Palliative Radiotherapy for Symptomatic Locally Advanced Gastric Cancer: A Phase II Trial
The hypothesis of this study is that a radiotherapy dose of 36Gy in 12 fractions, which equates to a BED of 48.6Gy, increases the response rates of symptom relief compared to historical controls.
- Trial name
- NCT01341756
- Testing
- Palliative Radiotherapy
- Where
- Singapore
- Volunteers
- 63 people
- Sponsor
- National University Hospital, Singapore
Palliative, Advanced Cancer
Immunotherapy And Palliative Radiotherapy Combined In Patients With Advanced Malignancy
Immunotherapy includes a class of medication called checkpoint inhibitors, which are a relatively new medication therapy for many types of cancer which are metastatic, meaning it has spread to other parts of the body.Immune…
- Conditions
- Palliative, Advanced Cancer, Immunotherapy, Radiation Therapy
- Trial name
- NCT03042156
- Testing
- Palliative Radiation Therapy
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University Health Network, Toronto
Head and Neck Carcinoma, Localized Head and Neck Carcinoma
Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy for Palliative Head and Neck Cancer Treatment (PULS-Pal)
This trial tests how well personalized ultra fractionated stereotactic adaptive radiotherapy (PULSAR) works together with HyperArc© radiation treatment planning technology for palliative (holistic pain and symptom control) tumor…
- Conditions
- Head and Neck Carcinoma, Localized Head and Neck Carcinoma, Metastatic Head and Neck Carcinoma, Recurrent Head and Neck Carcinoma
- Trial name
- PULS-Pal (NCT06572423)
- Testing
- Personalized ultrafractionated stereotactic adaptive radiotherapy, Volume Modulated Arc Therapy, Computed Tomography
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Cancer
Palliative Care and Oncology Survey on Terminology
The term '"cancer survivors" is widely used but has different definitions. One definition describes "cancer survivors" as individuals from the time of diagnosis throughout their lives, which includes people living with cancer and…
- Trial name
- POST (NCT05871996)
- Testing
- Palliative Care and Oncology Survey on Terminology (POST)
- Where
- 3 sites in Ireland, United Kingdom
- Volunteers
- 1,532 people
- Sponsor
- Our Lady's Hospice and Care Services
Cholangiocarcinoma, Biliary Stricture
Photodynamic Therapy (PDT) for Palliation of Cholangiocarcinoma
Successful palliation of biliary obstruction is the main goal for reducing morbidity and mortality in patients with biliary disease and biliary obstruction related to cholangiocarcinoma.
- Conditions
- Cholangiocarcinoma, Biliary Stricture, Biliary Obstruction, Bile Duct Cancer
- Trial name
- NCT01755013
- Testing
- Photodynamic Therapy
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Weill Medical College of Cornell University
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