Clinical trials: Palliative Cancer
Pancreatic Cancer
EUS Guided Neurolysis Celiac Block w/wo Bupivacaine in Patient Being Treated Palliatively for Pancreatic Cancer
The goal of this project is to determine if EUS-CPN without Bupivacaine (versus EUS-CPN with Bupivacaine) can reduce pain scores and improve quality of life in patients with inoperable pancreatic cancer by reducing the morbidity…
- Trial name
- EUS-CPN (NCT02682082)
- Testing
- Endoscopic ultrasound-guided celiax plexus neurolysis, Bupivacaine
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Cachexia; Cancer, Advanced Cancer
Routine Evaluation of People Living With Cancer
People with incurable cancer often have complex individual needs, however there are several common themes encountered when considering this group.
- Conditions
- Cachexia; Cancer, Advanced Cancer, Quality of Life
- Trial name
- REVOLUTION (NCT04406662)
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- University of Edinburgh
Cancer
Living Well With Serious Illness "Wicokuje Sica Tuha Akisniya Wiconi": Wawokiya Health Advocate Intervention
Informed by a Community Advisory Board (CAB) and community assessments performed in the first phase of work funded through R01CA240080, this study will test a wawokiya (one who helps) health advocate (WHA)-based palliative care…
- Trial name
- NCT05208606
- Testing
- Wawokiya Health Advocate
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Brain Metastases, Brain Metastasis
Feasibility of a Cognitive Stepped Care Program for Adults With Brain Metastases
Background: Cognitive symptoms are common and often severe in patients with brain metastases, significantly impacting their quality of life and ability to manage cancer care.
- Trial name
- NCT07355348
- Testing
- Cognitive Stepped Care Program (CSCP)
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- University Health Network, Toronto
Cancer
Caregivers' and Cancer Survivors' Psychological Distress & Symptom Management
Sample: The sample will be 298 ethnically diverse (30% Hispanic) survivors who have a new diagnosis or localized recurrence of solid tumor cancer and elevated depression or anxiety and their informal caregivers.
- Trial name
- NCT03743415
- Testing
- Handbook, TIP-C plus Handbook
- Where
- United States
- Volunteers
- 908 people
- Sponsor
- University of Arizona
Cancer, Cachexia
Resting Energy Expenditure in Palliative Cancer Patients
The study purpose is to measure REE by indirect calorimetry and to determine limits of agreement with confidence intervals between measured REE and predictive equations for determination of energy requirements in patients with…
- Trial name
- REPAT (NCT06206785)
- Where
- Norway
- Volunteers
- 160 people
- Sponsor
- Norwegian University of Science and Technology
Neoplasms, Palliative Care
Acupuncture in Palliative Cancer Care
Research question: Can acupuncture improve symptom control and quality of life (QOL) in patients with advanced incurable cancer? The purposes of this study is to investigate the feasibility of performing a randomized trial with…
- Trial name
- NCT00302185
- Testing
- Acupuncture, Nurse-led supportive care
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- British Columbia Cancer Agency
Non-Small Cell Lung Cancer
A Randomized Phase III Study of Palliative Radiation of Advanced Central Tumors With Intentional Avoidance of the Esophagus
A randomized phase II study of palliative radiation of advanced central lung tumors with intentional avoidance of the esophagus.
- Trial name
- PROACTIVE (NCT02752126)
- Testing
- Conventional radiotherapy, Esophageal-Sparing Intensity-Modulated Radiotherapy
- Where
- 7 sites in Canada
- Volunteers
- 90 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hepatocellular Carcinoma Stage IIIB, Cholangiocarcinoma, Intrahepatic
Evaluation the Palliative Effects of Colchicine on Primary Hepatic Malignant Tumors Unable to Receive Curative Treatment
This trial is to evaluate the palliative effects of colchicine on primary hepatic malignancy using the Department of Health R.O.C. approved doses and methods of administration.
- Conditions
- Hepatocellular Carcinoma Stage IIIB, Cholangiocarcinoma, Intrahepatic, Cholangiocarcinoma; With Hepatocellular Carcinoma, Hepatocellular Carcinoma Stage IV
- Trial name
- NCT04264260
- Testing
- Colchicine Tablets
- Where
- Taiwan
- Volunteers
- 42 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Carcinoma, Non-Small-Cell Lung
Prospective Trial of Induction Immunotherapy in Locally Advanced or Oligometastatic NSCLC Without a Primary Curative Option
In a certified lung- cancer center, patients with NSCLC and a potentially curative stage (including patients with oligometastatic disease) are prospectively enrolled if curative treatment (either definitive radio-chemotherapy or…
- Trial name
- KOMPASSneo (NCT04926584)
- Testing
- induction therapy
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Klinikum Esslingen
Head and Neck Cancer
A Randomized Comparative Study of a Weekly Versus Every Other Week Nurse Practitioner-led Symptom Management Clinic for Head and Neck Cancer Patients Undergoing Concurrent Chemotherapy and Radiation
A retrospective chart review of patients receiving concurrent chemoradiotherapy for oropharynx cancer was performed to compare clinical data for patients treated prior to the initiation of the NP clinic with those subsequently…
- Trial name
- NCT02085525
- Testing
- Nurse Practitioner Clinic
- Where
- United States
- Sponsor
- University of Michigan Rogel Cancer Center
Breast Cancer, Nursing
The Effect of the Mobile Application-based Support Program on the Outcomes of Breast Cancer Patients in the Pandemic
Breast cancer remains the most common type of cancer in the world. Cancer itself and chemotherapy treatment, which is one of the most important treatment steps, may cause unwanted physical, social and psychological effects…
- Trial name
- NCT05739175
- Testing
- Mobile Application with Interactive Nurse Support
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ankara University
Pancreatic Cancer, Adult
To Evaluate the Preliminary Efficacy of Our Digitally Enhanced CHW-led Intervention in Newly Diagnosed PDAC
The goal of this clinical trial is to learn if a community health worker led intervention that helps facilitate palliative care works to treat newly-diagnostic pancreatic cancer.
- Trial name
- NCT07591571
- Testing
- PAL-CHW-PDAC, Usual Care with Attention Control
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Loma Linda University
Lung Cancer
Effects of Palliative Care on Quality of Life and Symptom Control in Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery
RATIONALE: Palliative care may be more effective than standard care in improving quality of life and symptoms in patients with lung cancer.
- Trial name
- NCT00823732
- Testing
- educational intervention, medical chart review, questionnaire administration
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- City of Hope Medical Center
Quality of Life
Exploring The Role Of Palliative Care In Phase 1 Enrolled Pediatric Oncology Patients
This study is being conducted to learn more about the patient/family experience when opting to enroll in Phase I clinical trials and their quality of life (QOL) while receiving experimental therapy.
- Trial name
- NCT05412563
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- St. Jude Children's Research Hospital
Metastatic Prostate Cancer
PROMET-BR - Molecular Profiling of Metastatic Prostate Cancer: a Brazilian Cohort
PROMET-BR is an observational, retrospective and prospective real-world study in Brazil designed to characterize clinically relevant molecular alterations in metastatic prostate cancer and explore their association with patient…
- Trial name
- PROMET-BR (NCT07560215)
- Testing
- Archived FFPE tissue biopsy and/or newly acquired liquid biopsy for molecular profiling.
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- AstraZeneca
Cancer
Consultation to Announce the End of Chemotherapy and Specific Treatments in an Outpatient Setting: Evaluation of the Psychological Impact and Information Exchange.
The average 5-year survival rate for patients diagnosed with cancer in France is estimated at 53%. Nearly half of all patients diagnosed with cancer are not alive 5 years after diagnosis Discontinuation of anti-tumor treatments…
- Trial name
- CACTuS (NCT05293925)
- Testing
- announcement of cessation of treatment
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Institut Curie
Depressive Symptoms Mild to Moderate in Severity, Anxiety
Effects of Intranasal Ketamine on Depression and Anxiety in Palliative Care Cancer Patients
With progression of cancer, patients and their caregivers experience challenging emotional distress, which can make them feel depressed and very anxious. Patients with advanced cancer often do not have long to live.
- Conditions
- Depressive Symptoms Mild to Moderate in Severity, Anxiety, Quality of Life (QOL), Caregiver Burden
- Trial name
- Keta-Care (NCT06665568)
- Testing
- Intranasal ketamine hydrochloride
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Neoplasms
Oral Symptom Assessment Scale (OSAS): Validity and Reliability
Oral (mouth) symptoms are very common and often bothersome in patients with cancer. The best way to assess these symptoms is using a patient-rated symptom assessment scale.
- Trial name
- NCT04932317
- Where
- Ireland
- Volunteers
- 54 people
- Sponsor
- Our Lady's Hospice and Care Services
Malignant Solid Neoplasm
Interstitial Photodynamic Therapy Following Palliative Radiotherapy in Treating Patients With Inoperable Malignant Central Airway Obstruction
This phase I/II trial studies the side effects of interstitial photodynamic therapy following palliative radiotherapy and how well it works in treating patients with inoperable malignant central airway obstruction.
- Trial name
- NCT06306638
- Testing
- Biospecimen Collection, Computed Tomography, Endobronchial Ultrasound Bronchoscopy
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- Roswell Park Cancer Institute
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.