Clinical trials: Palliative Cancer
Cancer
Early Intervention vs. Standard Palliative Care in Improving End-of-Life Care in Advanced Cancer Patients
RATIONALE: Palliative care may help patients with advanced cancer live more comfortably. PURPOSE: This randomized clinical trial is studying an early intervention palliative care program to see how well it works compared to a…
- Trial name
- NCT00253383
- Testing
- counseling intervention, educational intervention, psychosocial assessment and care
- Where
- 2 sites in United States
- Volunteers
- 329 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Cancer, Congestive Heart Failure
Expanding Access to Home-Based Palliative Care
This study will test the effectiveness of integrating an evidence-based model of home-based palliative (HBPC) within primary care clinics on patient and caregiver outcomes.
- Conditions
- Cancer, Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT03128060
- Testing
- Home-based palliative care, Enhanced usual care
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Southern California
Advanced Prostate Cancer, Lower Urinary Tract Symptoms
TUPKRP Combined With MAB Therapy for LUTS/PCa
Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide, accounting for 15% of all male cancers. In 2015, there were 220,800 estimated new cases of prostate cancer and 27,540 deaths by PCa, making…
- Conditions
- Advanced Prostate Cancer, Lower Urinary Tract Symptoms, Quality of Life, Overall Survival
- Trial name
- NCT03701659
- Testing
- Surgery combinate with Endocrine therapy, Endocrine therapy
- Volunteers
- 100 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Chronic Hepatitis B, Hepatocellular Carcinoma
Tenofovir Antiviral Therapy Following Transarterial Chemoembolization for HBV Related Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is one of the most common solid cancers worldwide, and chronic hepatitis B virus (HBV) infection is the most common etiology of HCC in Asia.
- Trial name
- NCT01872988
- Testing
- Tenofovir
- Where
- 4 sites in Taiwan
- Volunteers
- 320 people
- Sponsor
- Taichung Veterans General Hospital
Carcinoma, Hepatocellular
Oxaliplatin + 5-FluoroUracil/LeucoVorin (5-FU/LV) (FOLFOX4) Versus Doxorubicin as Palliative Chemotherapy in Advanced Hepatocellular Carcinoma Patients
Primary: Overall Survival (OS) Secondary: Time to Tumor Progression (TTP) Response Rate (RR) Improvement of Quality of Life (QoL) Safety Secondary resection rate
- Trial name
- EACH (NCT00471965)
- Testing
- Oxaliplatin + 5-Fluorouracil/Leucovorin, Doxorubicin
- Where
- 4 sites in China, South Korea and 2 more
- Volunteers
- 371 people
- Sponsor
- Sanofi
Inoperable Gastric Cancer
FOLFIRI Versus Docetaxel and Cisplatin as a Second-line Chemotherapy After Failure of First-line Chemotherapy in Advanced Gastric Cancer
Patients diagnosis with inoperable gastric cancers are treated with palliative chemotherapy. Palliative chemotherapy had proven to be better overall survivals and quality of life in unresectable advanced gastric cancer.
- Trial name
- NCT03067792
- Testing
- 5-fluorouracil, irinotecan and leucovorin, docetaxel and cisplatin
- Volunteers
- 52 people
- Sponsor
- Yonsei University
Cancer, Suffering
The Immediate Effect of Mindfulness-Based Supportive Therapy on Palliating Suffering in Palliative Care Cancer Patients
The was a parallel group, single-blinded, randomized controlled trial comparing the effectiveness of 30-minute mindfulness-based supportive therapy versus supportive listening in reducing suffering among patients with cancer.
- Trial name
- NCT05010239
- Testing
- 30-minute Mindfulness-Based Supportive Therapy, 30-minute supportive listening
- Where
- Malaysia
- Volunteers
- 68 people
- Sponsor
- University Malaysia Sarawak
Lung Cancer
Piloting 'mPal,' a Multilevel Strategy for Palliative Care Implementation
The purpose of this study is to assess the feasibility and acceptability of mPal, a multilevel implementation strategy to improve palliative care use among advanced stage lung cancer patients receiving cancer treatment.
- Trial name
- NCT05270395
- Testing
- mPal
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Laurie McLouth
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Early Palliative Care for Patients With Haematological Malignancies
Patients suffering from haematological disease present symptoms of discomfort and currently benefit from palliative care skills only for the management of their end-of-life.
- Conditions
- Acute Myeloid Leukemia, Myelodysplastic Syndrome, Diffuse Large B Cell Lymphoma, Palliative Care
- Trial name
- CALVI (NCT03800095)
- Testing
- Early palliative care integration
- Where
- 6 sites in France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Clermont-Ferrand
Advanced Cancer
A Primary Palliative Care Intervention for Patients With Advanced Cancer
The overall goal of this study is to test whether a nurse-led intervention to improve provision of primary palliative care within oncology practices (CONNECT) can decrease morbidity for patients with advanced cancer and their…
- Trial name
- CONNECT (NCT02712229)
- Testing
- CONNECT
- Where
- United States
- Volunteers
- 1,290 people
- Sponsor
- University of Pittsburgh
Incurable Cancer
DOMUS: A Trial of Accelerated Transition From Oncological Treatment to Continuing Palliative Care at Home
Danish studies have shown that the majority of palliative cancer patients wish to be cared for and spend the rest of their lives at home.
- Trial name
- DOMUS (NCT01885637)
- Testing
- Transition program
- Where
- Denmark
- Volunteers
- 340 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Gynecological Cancer
Investigation of the Effects of Online Education Application on Gynecological Cancer Patients Receiving Chemotherapy
The aim of the study was to examine the effect of online nursing education given to women diagnosed with gynecological cancer and receiving chemotherapy. It was conducted as a randomized controlled experimental study.
- Trial name
- NCT06574256
- Testing
- Chemotherapy symptom Management Online Education
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Manisa Celal Bayar University
Lung Cancer, Non-small Cell Lung Cancer
Prospective Study to Determine Impact of Early Palliative Care Consult on Quality of Life (QOL), Cancer Related Symptoms In Advanced Lung Cancer Patients: Thoracic Pilot Project
The goal of this study is to learn about the quality of life (QOL) in participants with advanced lung cancer.
- Trial name
- NCT02459002
- Testing
- QOL Questionnaire, Caregiver Satisfaction Questionnaire
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- M.D. Anderson Cancer Center
Terminal Cancer
Nasal Fentanyl and Buccal Midazolam for Dying Patients
When patients are dying they become unable to take oral medication and if they develop symptoms (e.g. pain or agitation) they need to be given a subcutaneous injection of medication.
- Trial name
- NCT02009306
- Testing
- PecFent and Epistatus, Standard subcutaneous medication, Epistatus Alone
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Cancer, Advanced Solid Tumors, Malnutrition
A Nutrition and Exercise Program With Olanzapine Compared to Olanzapine Alone: A Trial in Patients With Advanced Tumors
Cancer patients have a higher risk of malnutrition because of their illness and treatments. This can lead to weight loss, weak muscles, less effective cancer therapy, or stronger side effects.
- Trial name
- SwissNutriAct2 (NCT07722806)
- Testing
- Standardized nutritional program, standardized exercize program, Whey protein supplement with added leucine and β-hydroxy-β-methylbutyrate (HMB)
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Kantonsspital Winterthur KSW
Self Care, Family Caregivers
Feasibility Study of a Home-based Physical Activity Intervention for Family Caregivers of People With Advanced Cancer
The purpose of this study is to develop an individually tailored home-based physical activity intervention for family caregivers of people with advanced cancer and assess the feasibility of a future randomized controlled trial…
- Trial name
- NCT02211092
- Testing
- Physical activity intervention, Usual care
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Jewish General Hospital
Malignant Neoplasms of Independent (Primary) Multiple Sites
Difference in the Estimation of Prognosis
Objectives: Primary Objective: The primary objective is to identify the difference in the estimation of prognosis of advanced cancer patients between medical oncologists, gynecological oncologists, and palliative care physicians
- Trial name
- NCT03115528
- Testing
- Estimation of Prognosis Questionnaire
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cancer-Related Pain
The Effectiveness of Progressive Muscle Relaxation Technique in Reducing Cancer-related Pain
This randomized controlled trial was designed to evaluate the effectiveness of the Progressive Muscle Relaxation (PMR) technique in reducing Cancer-related Pain (CRP) in patients receiving palliative care in Jordan.
- Trial name
- NCT04436705
- Testing
- Progressive Muscle Relaxation (PMR) technique
- Volunteers
- 148 people
- Sponsor
- University of Jordan
Leukemia, Acute, AML, Adult
Palliative Care Oncology in Patients With Relapsed, Refractory, and High-Risk Leukemias or MDS
The purpose of this study is to estimate the potential benefit of early and continued palliative care (PC) consultation on end of life issues.
- Conditions
- Leukemia, Acute, AML, Adult, ALL, Adult, Myelodysplastic Syndromes
- Trial name
- NCT04482894
- Testing
- Palliative Care Visits
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Virginia
Gastric Cancer
Electrochemotherapy for Non-curable Gastric Cancer
This is an explorative, phase I clinical trial. The aim of this study is to establish the safety and efficacy of electrochemotherapy for non-curable gastric cancer.
- Trial name
- NCT04139070
- Testing
- Bleomycin
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- Zealand University Hospital