Clinical trials: Palliative Cancer
Advanced Cancer
Palliative Care Referral System (PCRS) for Cancer Patients With Advanced Disease
Early palliative care (EPC) in the clinical pathway of advanced cancer patients improves symptom control, quality of life and has a positive impact on overall quality of care.
- Trial name
- PCRSS (NCT04936568)
- Testing
- Palliative Care Referral System - PCRS
- Where
- Italy
- Volunteers
- 380 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Neoplasms
A Psychosocial Intervention Plus Early Palliative Care in the Reduction of Depression of Advanced Cancer Patients
The purpose of this study is to determine whether a brief psychosocial intervention together with early palliative care are feasible, acceptable and effective in the reduction of depressive symptoms of patients with advanced…
- Trial name
- PREPArE (NCT02133274)
- Testing
- Brief Psychosocial Intervention, Early Palliative Care
- Where
- Brazil
- Volunteers
- 63 people
- Sponsor
- Barretos Cancer Hospital
Cancer
Existential Issues in Elderly People With Cancer
The purpose is to describe, interpret and provide a detailed understanding of what it means to be elderly people with cancer who receive treatment in specialized health care.
- Trial name
- NCT01309815
- Where
- Norway
- Volunteers
- 21 people
- Sponsor
- Sykehuset Innlandet HF
Solid Cancer in a Palliative Situation With Ascites
Serum-Ascites Albumin Gradient Analysis in Cancer Patients in Palliative Care
Current recommendations do not recommend the concomitant administration of albumin after ascites puncture in patients with ascites neoplasia unlike cirrhotic ascites.
- Trial name
- AGASA-SP (NCT03463655)
- Testing
- cirrhotic albumin, serum albumin
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Institut Paoli-Calmettes
Unresectable Hilar Cholangiocarcinoma
Quality of Life in Patients With Unresectable Hilar Cholangiocarcinoma on Palliative Metallic Stent Versus Plastic Stent
The purpose of this study is to compare the quality of life in patients with unresectable hilar cholangiocarcinoma on palliative metallic stent versus plastic Stent.
- Trial name
- NCT00746538
- Testing
- biliary stent
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Khon Kaen University
Cancer (With or Without Metastasis), Interstitial Lung Disease (ILD)
Hypnosis on Breathlessness Mastery in Patients With Persistent Dyspnea
Persistent dyspnea is a debilitating symptom, that is common and difficult to treat. This symptom is found in many different diseases including chronic obstructive pulmonary disease (COPD), interstitial lung disease (ILD)…
- Conditions
- Cancer (With or Without Metastasis), Interstitial Lung Disease (ILD), Chronic Heart Failure (CHF), COPD
- Trial name
- HYPNEA (NCT07173348)
- Testing
- Hypnosis
- Where
- Switzerland
- Volunteers
- 82 people
- Sponsor
- University Hospital, Geneva
Cancer
Surgery for Cancer With Option of Palliative Care Expert
Frequently people diagnosed with cancer experience physical and emotional symptoms during the course of their disease. These symptoms can be very distressing to both the patient and the family members.
- Trial name
- SCOPE (NCT03436290)
- Testing
- Palliative Care Intervention
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Vanderbilt University Medical Center
Pain, Cancer
Study to Compare the Safety and Tolerability of Sativex® in Patients With Cancer Related Pain
The purpose of this study is to assess the safety and tolerability of long term therapy with Sativex® and GW-2000-02.
- Trial name
- NCT00675948
- Testing
- Sativex, GW-2000-02
- Where
- United Kingdom
- Volunteers
- 43 people
- Sponsor
- Jazz Pharmaceuticals
Delirium, Locally Advanced Malignant Neoplasm
Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care
This phase II/IIII trial studies how well haloperidol and lorazepam work in controlling symptoms of persistent agitated delirium in patients with cancer that has spread to other places in the body undergoing palliative care.
- Conditions
- Delirium, Locally Advanced Malignant Neoplasm, Metastatic Malignant Neoplasm, Recurrent Malignant Neoplasm
- Trial name
- NCT03743649
- Testing
- Haloperidol, Lorazepam, Quality-of-Life Assessment
- Where
- 3 sites in United States, Brazil
- Volunteers
- 110 people
- Sponsor
- M.D. Anderson Cancer Center
Metastatic Cancer, Palliative Care
Impact of a Booklet-Question List on Cancer Patients or Their Families Seeking Prognostic Information During a Palliative Care Consultation
Prospective, randomized, multicentre phase III study to evaluate the level and type of information requested by patients or families during a palliative care consultation after they have been given the Booklet-Question List (BQL).
- Trial name
- QUEPAL (NCT02854293)
- Testing
- Booklet-Question List
- Where
- 5 sites in France
- Volunteers
- 121 people
- Sponsor
- Institut Curie
Advanced Cancer
The PediQUEST Response Intervention Study
PediQUEST Response proposes a new system of care that expects to improve quality of life in children, adolescents, and young adults with advanced cancer and their parents.
- Trial name
- NCT03408314
- Testing
- PediQUEST Response, Usual Cancer Care
- Where
- 6 sites in United States
- Volunteers
- 194 people
- Sponsor
- Joanne Wolfe, MD, MPH
Nausea, Vomiting
Does Acupressure Help Reduce Nausea and Vomiting in Palliative Care Patients? Formal Study
Pilot study completed - power calculation performed. Now formal double blind randomized study comparing active with placebo wristbands for nausea in palliative care patients to be carried out.
- Trial name
- NCT00550251
- Testing
- Acupressure Wrist Bands (Sea-Bands)
- Where
- United Kingdom
- Volunteers
- 58 people
- Sponsor
- Sue Ryder Care
Prostate Cancer
Leuprolide Acetate 3.75 mg Depot to Treat Prostate Cancer
The purpose of this study is to look at the efficacy and safety of leuprolide acetate in patients with prostate cancer.
- Trial name
- NCT00128531
- Testing
- leuprolide acetate
- Where
- 28 sites in United States, Austria and 7 more
- Volunteers
- 120 people
- Sponsor
- GP-Pharm
Intractable Pain, Palliative Care
Resiniferatoxin to Treat Severe Pain Associated With Advanced Cancer
This study will examine the safety of giving the experimental drug, resiniferatoxin (RTX), to treat severe pain in patients with advanced cancer. RTX is a chemical extracted from a cactus-like plant.
- Trial name
- NCT00804154
- Testing
- Intrathecal Resiniferatoxin
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Oesophageal Cancer, Oesophageal Disease
EndoVE endosCopic Treatment for Oesophageal and Gastric canceR
This project aims to establish the safety and efficacy of treating patients with inoperable oesophageal cancer or gastric cancer, using an endoscopic electroporation system (EndoVE) to facilitate direct chemotherapy tumour…
- Conditions
- Oesophageal Cancer, Oesophageal Disease, Gastric Cancer
- Trial name
- VECTOR (NCT04649372)
- Testing
- EndoVE
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Mirai Medical
Chronic Insomnia
The Effectiveness of Online Treatment for Insomnia in Cancer Survivors
Chronic insomnia affects more than 25% of cancer survivors, a rate double that of the general population. The Pan-Canadian sleep guideline for adults with cancer recommends Cognitive-Behavioral Therapy for Insomnia (CBT-I) as the…
- Trial name
- NCT02272712
- Testing
- Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 202 people
- Sponsor
- Ottawa Hospital Research Institute
Esophageal Cancer
A Trial of Palliative Chemotherapy, Radiation and Immune Treatment for Oesophageal Cancer: PALEO Study
The purpose of this study is to investigate the effects of the addition of the stereotactic body radiotherapy and durvalumab to a well tolerated 2 week chemotherapy and radiation treatment regimen in people with esophageal cancer…
- Trial name
- PALEO (NCT06290505)
- Testing
- Durvalumab
- Where
- 9 sites in Australia, New Zealand
- Volunteers
- 54 people
- Sponsor
- Australasian Gastro-Intestinal Trials Group
Pancreatic Cancer Metastatic
Conversion Surgery Vs. Palliative Care in Pancreatic Cancer Oligometastatic to the Liver
This study investigates the impact of surgical resection compared to palliative care in patients with oligometastatic pancreatic cancer limited to the liver.
- Trial name
- SONAR (NCT06690528)
- Testing
- Surgical resection of both the primary tumor and liver metastases
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- Azienda Ospedaliera di Padova
Breast Cancer Early Stage Breast Cancer (Stage 1-3), Endocrine Therapy
Symptom Monitoring Using Patient-Report to Improve Medication Use
This is an intervention targeting patients at risk for non-adherence to endocrine therapy after primary treatments for hormone-positive breast cancer.
- Trial name
- SyMPTOM (NCT06765707)
- Testing
- Pharmacist delivered symptom monitoring and management
- Where
- 4 sites in United States
- Volunteers
- 225 people
- Sponsor
- Medical College of Wisconsin
Stem Cell Transplant
In Person and mHealth Coping Skills Training for Symptom Management and Steps in Stem Cell Transplant Patients
Hematopoietic stem cell transplant (HCT) is an aggressive treatment for life-threatening cancers. HCT improves survival, but most HCT patients experience significant physical disability, which is exacerbated by persistent…
- Trial name
- Symptoms-Steps (NCT03859765)
- Testing
- HCT Symptoms and Steps
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
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